The DOI matches its Crossref record; 78 of the 78 references it cites were found in a registry or an index.
Evidence for an Autoimmune Pathogenesis of Vitiligo
Abstract
Vitiligo is a depigmenting disorder characterized by the development of white patches in various distributions, which are due to the loss of melanocytes from the epidermis. A variety of arguments from clinical observations to research findings in human and animal models support the hypothesis of autoimmunity and are reviewed in this article. The association with autoimmune diseases and organ‐specific autoantibodies is well known. Various effective treatment options have an immunosuppressive effect. Today the autoimmune pathogenesis of the disease has become a rapidly evolving field of research. Detection of circulating melanocyte antibodies in human and animal models implicates a possible role of humoral immunity. Histological and immunohistochemical studies in perilesional skin suggest the involvement of cellular immunity in vitiligo. Recently, T‐cell analyses in peripheral blood further support this hypothesis. Interestingly, new insights in the association of vitiligo and melanoma may help to clarify the role of autoimmunity in the development of vitiligo.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Ahonen, P., Myllärniemi, S., Sipilä, I., & Perheentupa, J. (1990) · New England Journal of Medicine · doi:10.1056/nejm199006283222601 · Cited by 1,077
High Frequency of Skin-homing Melanocyte-specific Cytotoxic T Lymphocytes in Autoimmune Vitiligo
Ogg, G. S., Rod Dunbar, P., Romero, P., Chen, J.-L., & Cerundolo, V. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.188.6.1203 · Cited by 460
Melanocyte Destruction after Antigen-Specific Immunotherapy of Melanoma
Yee, C., Thompson, J. A., Roche, P., Byrd, D. R., Lee, P. P., Piepkorn, M., Kenyon, K., Davis, M. M., Riddell, S. R., & Greenberg, P. D. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.11.1637 · Cited by 428
New Insights into the Pathogenesis of Vitiligo: Imbalance of Epidermal Cytokines at Sites of Lesions
Moretti, S., Spallanzani, A., Amato, L., Hautmann, G., Gallerani, I., Fabiani, M., & Fabbri, P. (2002) · Pigment Cell Research · doi:10.1034/j.1600-0749.2002.1o049.x · Cited by 301
Poole, I. C. L., van den Wijngaard, R. M., Westerhof, W., & Das, P. K. (1996) · Europe PMC (PubMed Central) · Cited by 282
Local Immune Response in Skin of Generalized Vitiligo Patients
van den Wijngaard, R., Wankowicz-Kalinska, A., Le Poole, C., Tigges, B., Westerhof, W., & Das, P. (2000) · Laboratory Investigation · doi:10.1038/labinvest.3780138 · Cited by 272
Review of the etiopathomechanism of vitiligo: A convergence theory
Le Poole, I. C., Das, P. K., van den Wijngaard, R. M. J. G. J., Bos, J. D., & Westerhof, W. (1993) · Experimental Dermatology · doi:10.1111/j.1600-0625.1993.tb00023.x · Cited by 268
The effects of ultraviolet radiation on the human immune system: EFFECTS OF UV ON THE IMMUNE SYSTEM
Duthie, Kimber, & Norval (1999) · British Journal of Dermatology · doi:10.1046/j.1365-2133.1999.02898.x · Cited by 245
Coupling and Uncoupling of Tumor Immunity and Autoimmunity
Bowne, W. B., Srinivasan, R., Wolchok, J. D., Hawkins, W. G., Blachere, N. E., Dyall, R., Lewis, J. J., & Houghton, A. N. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.190.11.1717 · Cited by 239
Palermo, B., Campanelli, R., Garbelli, S., Mantovani, S., Lantelme, E., Brazzelli, V., Ardigó, M., Borroni, G., Martinetti, M., Badulli, C., et al. (2001) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2001.01408.x · Cited by 223
Cited by
Bergqvist, C., & Ezzedine, K. (2020) · Dermatology · doi:10.1159/000506103 · Cited by 799
Vitiligo: A comprehensive overview
Alikhan, A., Felsten, L. M., Daly, M., & Petronic-Rosic, V. (2011) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2010.11.061 · Cited by 708
Hua, C., Boussemart, L., Mateus, C., Routier, E., Boutros, C., Cazenave, H., Viollet, R., Thomas, M., Roy, S., Benannoune, N., et al. (2016) · JAMA Dermatology · doi:10.1001/jamadermatol.2015.2707 · Cited by 655
Costa, R., Carneiro, B. A., Agulnik, M., Rademaker, A. W., Pai, S. G., Villaflor, V. M., Cristofanilli, M., Sosman, J. A., & Giles, F. J. (2017) · Oncotarget · doi:10.18632/oncotarget.13315 · Cited by 123
Chung, H., Jung, H., Lee, J.-H., Oh, H. Y., Kim, O. B., Han, I.-O., & Oh, E.-S. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.541177 · Cited by 30
Metadata
- Authors
- Ongenae, K., Van Geel, N., & Naeyaert, J.
- Venue
- Pigment Cell Research
- Publisher
- Wiley
- Published
- 2003-03-05
- Volume
- 16
- Issue
- 2
- Pages
- 90-100
- ISSN
- 0893-5785 (ISSN-L)
- 1600-0749
- OpenAlex
- W2058630030
- Cited by
- 437
- References
- 78
- FWCI
- 7.37
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Evidence for an Autoimmune Pathogenesis of Vitiligo. https://app.cochat.ai/papers/10.1034/j.1600-0749.2003.00023.x
- The paper
- Ongenae, K., Van Geel, N., & Naeyaert, J. (2003). Evidence for an Autoimmune Pathogenesis of Vitiligo. Pigment Cell Research. https://doi.org/10.1034/j.1600-0749.2003.00023.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
