Classical conditioning after cerebellar lesions in humans.

Abstract

We explored classical conditioning in human subjects who had lesions in their cerebellar circuitry. Seven patients with damage to cerebellar structures and matched control subjects underwent simple delay tone-airpuff conditioning. Eyelid conditioned response (CR) acquisition was severely disrupted in the patient group, whereas autonomic CRs and slow cortical potentials developing between conditioned stimulus (CS) and the unconditioned stimulus (UCS) were unaffected. Results are consistent with animal studies and earlier case reports indicating that intact cerebellar structures are necessary for the acquisition of classically conditioned motor responses.

Cited by (7)

1. Fears, phobias, and preparedness: toward an evolved module of fear and fear learning
   Öhman, Arne, Mineka, Susan · 2001 · Psychological Review
2. Untitled work
   2009
3. Close Interrelation of Motor Development and Cognitive Development and of the Cerebellum and Prefrontal Cortex
   Diamond, Adele · 2000 · Child Development
4. Cerebral Representation of One’s Own Past: Neural Networks Involved in Autobiographical Memory
   Fink, Gereon R., Markowitsch, Hans J., Reinkemeier, Mechthild, Bruckbauer, Thomas, Kessler, Josef, Heiss, Wolf-Dieter · 1996 · The Journal of Neuroscience
5. The Neuroscience of Mammalian Associative Learning
   Fanselow, Michael S., Poulos, Andrew M · 2005 · Annual Review of Psychology

See all 267