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Probability of relapse after recovery from an episode of depression
Abstract
Examined relapse rates in those individuals who have experienced an episode of unipolar depression as a function of the number of previous episodes, gender, age at onset of the episode (less than 40 vs. greater than 40), time since a previous episode, and depression level at time of interview. From of 6,742 participants, 2,046 were interviewed; of these, 1,130 had at least one, 513 reported a second and 173 reported a third episode. The probability for relapse was positively related to number of previous episodes, being female, depression level at time of interview, but not to age at onset (less than 40 vs. greater than 40). Women were also more likely to have more severe episodes. Participants with elevated depression symptoms reported a greater number of previous episodes. Following the first episode, there was a decline in hazard rate for men but not women; following the second episode, there was no change in vulnerability for men; for women, the results were ambiguous.
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“Many studies showed that sociodemographic factors such as younger age, women, and those who have never been married were at higher risk of recurrence [7, 11–15]; however, results of other studies on these risk factors have been inconsistent.”
From Predictors of recurrence of major depressive disorder (2020) · cites this paper as [17]
In the citing paper
“In terms of age at onset and gender, the results of our study replicated results of several earlier studies showing that age at onset of first MDE [17, 18, 59–60] and gender [16, 18, 59–61] did not predict subsequent episode of MDE.”
From Predictors of recurrence of major depressive disorder (2020) · cites this paper as [17]
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Self-citation
Metadata
- Authors
- Lewinsohn, P. M., Zeiss, A. M., & Duncan, E. M.
- Affiliations
- Oregon Research Institute (US)
- ORCID
- Zeiss, Antonette M.
- Venue
- Journal of Abnormal Psychology
- Published
- 1989-05
- Volume
- 98
- Issue
- 2
- Pages
- 107-116
- ISSN
- 0021-843X (ISSN-L)
- 1939-1846
- OpenAlex
- W2022630246
- Cited by
- 149
- References
- 0
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 2 · 2022: 2 · 2021: 3 · 2020: 2 · 2019: 1 · 2018: 3 · 2017: 4 · 2016: 3 · 2015: 4 · 2014: 5 · 2013: 3 · 2012: 1
- FWCI
- 3.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Abnormal Psychology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (MH 35672)
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- relapse, major depressive disorder, recurrent depression, gender differences, age of onset, depression severity, hazard function
- MeSH terms
- Actuarial Analysis, Adolescent, Adult, Aged, Depressive Disorder, Female, Humans, Male, Middle Aged, Oregon, Probability, Recurrence, Retrospective Studies, Sex Factors
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