Cited by 234Mental Health Research TopicsAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPsychometric Methodologies and Testing

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What can specificity designs say about causality in psychopathology research?

Garber, Judy, Hollon, Steven D.·1991·Psychological Bulletin

DOI 10.1037/0033-2909.110.1.129

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Abstract

Specificity designs in psychopathology research are used to examine whether a variable is unique to a given disorder. When nonspecificity is observed, it typically is assumed that the variable in question is not a cause of the disorder, but is instead a nonspecific consequence of general psychopathology. Such reasoning is flawed, however, because it fails to distinguish between testing a particular causal model containing the variable versus testing the causal status of the particular variable within the model. A variable may be nonspecific, but still causal, if it is one of several multiple interacting causes or if a nosological error has been made. A recognition of these complexities has implications for the nature of the psychopathology control group selected.

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Authors: Garber, J., & Hollon, S. D.
Affiliations: Vanderbilt University (US)
ORCID: Garber, Judy
Hollon, Steven D.
Venue: Psychological Bulletin
Publisher: American Psychological Association (APA)
Published: 1991
Volume: 110
Issue: 1
Pages: 129-136
ISSN: 0033-2909 (ISSN-L)
1939-1455
DOI: 10.1037/0033-2909.110.1.129
OpenAlex: W2024035006
Cited by: 233
References: 33
Citations by year: 2026: 4 · 2025: 7 · 2024: 5 · 2023: 8 · 2022: 6 · 2021: 5 · 2020: 4 · 2019: 6 · 2018: 5 · 2017: 2 · 2016: 5 · 2015: 9 · 2014: 6 · 2013: 8 · 2012: 7
FWCI: 17.51
Type: journal article
Language: en
Open access: closed
Locations: Psychological Bulletin (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Social Sciences › Decision Sciences › Management Science and Operations Research › Psychometric Methodologies and Testing
Keywords: non-specificity, causality, psychopathology, causal models, disease classification, control groups
MeSH terms: Mental Disorders, Depressive Disorder, Humans, Models, Psychological, Psychopathology, Risk Factors

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