The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Electrolytic lesions of the amygdala block acquisition and expression of fear-potentiated startle even with extensive training but do not prevent reacquisition.
Abstract
Lesions of the amygdala have been shown to block the expression of fear-potentiated startle (increased acoustic startle in the presence of a cue previously paired with shock). In the present study, bilateral lesions of the central nucleus of the amygdala given after extensive training totally blocked the expression of fear-potentiated startle but did not prevent reacquisition. In contrast, when the lesions were made before any training, the lesioned rats did not show potentiated startle even with extensive training. Thus, the central nucleus of the amygdala normally seems to be required for the initial acquisition and expression of potentiated startle regardless of the degree of learning. However, reacquisition of potentiated startle can occur without the central nucleus, which implies the presence of a secondary brain system that can compensate for the loss of the central nucleus of the amygdala under some circumstances.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Functionally, CEA has been implicated in learning and expression of fear responses,105, 106, 107 as well as the expression of stress-induced anxiety behaviors.108, 109, 110, 111, 112, 113”
From Preferential loss of dorsal-hippocampus synapses underlies memory impairments provoked by short, multimodal stress (2014) · cites this paper as [106]
Citations
Cites
The Rat Brain in Stereotaxic Coordinates
Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585
Falk, J. L. (1973) · Contemporary Psychology · doi:10.1037/0011818 · Cited by 2,288
The amygdala: Neurobiological aspects of emotion, memory, and mental dysfunction.
Aggleton, J. P. (1992) · Wiley-Liss eBooks · Cited by 1,536
Marburg, O. (2007) · Stereotactic and Functional Neurosurgery · doi:10.1159/000105833 · Cited by 387
Memory: Interdisciplinary Approaches
(1989) · Springer eBooks · doi:10.1007/978-1-4612-3500-2 · Cited by 127
Cited by
Sorted by citations
Items 101–139 of 139
The beginning of an alternative view of the neurobiology of emotion
Mendoza, S. P., & Ruys, J. D. (2001) · Social Science Information · doi:10.1177/053901801040001003 · Cited by 10
Weber, M. F., & Richardson, R. (2004) · Behavioral Neuroscience · doi:10.1037/0735-7044.118.5.965 · Cited by 9
Williams, A. R., Kim, E. S., & Lattal, K. M. (2019) · Learning & Memory · doi:10.1101/lm.048439.118 · Cited by 12
Kamada, T., & Hata, T. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.07.027 · Cited by 9
Lelos, M. J., & Good, M. A. (2012) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2012.03.001 · Cited by 10
Liang, K. (2009) · The Chinese Journal of Physiology · doi:10.4077/cjp.2009.amk023 · Cited by 8
The functional value of sound and exploratory behaviour in detelencephalated pigeons
Ferrari, E. A. D. M., Faleiros, L., Cerutti, S. M., & de Oliveira, A. M. (1999) · Behavioural Brain Research · doi:10.1016/s0166-4328(98)00146-6 · Cited by 8
Luyten, L., Vansteenwegen, D., van Kuyck, K., & Bart (2011) · Acta Neurobiologiae Experimentalis · doi:10.55782/ane-2011-1855 · Cited by 7
Neural systems involved in fear and anxiety based on the fear-potentiated startle test
Davis, M. (2007) · Elsevier eBooks · doi:10.1016/b978-012372540-0/50013-3 · Cited by 6
Self-citationRole of corticosterone in trace and delay conditioned fear-potentiated startle in rats.
Burman, M. A., Hamilton, K. L., & Gewirtz, J. C. (2010) · Behavioral Neuroscience · doi:10.1037/a0018911 · Cited by 7
Pavlovian Fear Conditioning Function, Cause, and Treatment
Fanselow, M. S., & Sterlace, S. R. (2014) · eScholarship (California Digital Library) · Cited by 7
Pérez-Acosta, A. M. (2005) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) · Cited by 6
Maren, S. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809324-5.21090-0 · Cited by 5
Pistell, P. J., & Falls, W. A. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.07.012 · Cited by 4
Effects of lesions of the central nucleus of the amygdala on conditioned fear responses in rats
Tazumi, T., & Okaichi, H. (1998) · Japanese Journal of Animal Psychology · doi:10.2502/janip.48.55 · Cited by 4
Sex Differences in Retrieval of Context Fear: Behavioral and Neural Mechanisms
Keiser, A. A. (2018) · Deep Blue (University of Michigan) · Cited by 2
Tazumi, T., & Okaichi, H. (1999) · The Japanese journal of psychology · doi:10.4992/jjpsy.70.352 · Cited by 2
Involvement of the Amygdala in Two Different Forms of the Inhibitory Avoidance Task
Liang, K., Yen, C., Chang, C., & Chen, C.-C. (2008) · Springer eBooks · doi:10.1007/978-4-431-73242-6_10 · Cited by 1
Psychophysiological and fMRI investigations of tobacco cue reactivity.
Engelmann, J. M. (2010) · University of Minnesota Digital Conservancy (University of Minnesota)
Henn, J. C. (2002) · Research Online (University of Wollongong)
Electrophysiology of the rat medial prefrontal cortex and amygdala during behaviour
Magony, A. (2015) · University of Birmingham Institutional Research Archive (University of Birmingham)
MODULATION OF LOCUS COERULEAR NEURONAL ACTIVITY BY THE CENTRAL NUCLEUS OF THE AMYGDALA
Ramsooksingh, M. D. (2008) · D-Scholarship@Pitt (University of Pittsburgh)
Fear conditioning and extinction: Basic neuronal mechanisms related to PTSD
Davis, M. (1994) · European Neuropsychopharmacology · doi:10.1016/0924-977x(94)90075-2
Self-citationTazumi, T., & Okaichi, H. (2002) · PSYCHOLOGIA · doi:10.2117/psysoc.2002.80
Barnett, S. T. C. (2006) · UC Research Repository (University of Canterbury) · doi:10.26021/6083
Ganev, J. (2007) · UC Research Repository (University of Canterbury) · doi:10.26021/6092
김유라, Chae, J., & Lee, K. (2011) · 대한정신약물학회지
Tazumi, T. (2000) · Japanese Journal of Animal Psychology · doi:10.2502/janip.50.171
정지운, 김문수, & Lim, H. M. (2008) · 한국심리학회지: 인지 및 생물 · doi:10.22172/cogbio.2008.20.4.006
Optogenetic and pharmacological dissection of a neuropeptide circuit that gates sustained fear
Asok, A. (2024) · Library, Museums and Press - UDSpace (University of Delaware) · doi:10.58088/a0ja-xc85
Genetic analysis of emotional memory in AMPA and NMDA receptor mutant mice
Arcos-Díaz, D. P. (2011) · heiDOK (Heidelberg University) · doi:10.11588/heidok.00012751
Investigation of Cellular and Molecular Mechanisms Involved in Contextual Fear Memory Encoding
Chaaya, N. (2019) · Queensland University of Technology · doi:10.5204/thesis.eprints.134258
Jackson, J. M. (2005) · University of Canterbury Research Repository (University of Canterbury) · doi:10.26021/10962
Sandi, C. (2014) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.718297966.793492714
Fear, Pain and the Amygdaloid Complex
van Nobelen, M. (2009) · UC Research Repository (University of Canterbury) · doi:10.26021/7775
Luyo, Z. N. M., Heerbrandt, R. S., Boden, A. F., Keumeni, F. E. E., Britten, R. A., Wellman, L. L., & Sanford, L. D. (2026) · Life · doi:10.3390/life16101638
Metadata
- Authors
- Kim, M., & Davis, M.
- Affiliations
- Yale University (US)
- Venue
- Behavioral Neuroscience
- Published
- 1993
- Volume
- 107
- Issue
- 4
- Pages
- 580-595
- ISSN
- 0735-7044 (ISSN-L)
- 1939-0084
- OpenAlex
- W2038679538
- Cited by
- 139
- References
- 5
- Citations by year
- 2026: 1 · 2024: 1 · 2020: 3 · 2019: 2 · 2018: 3 · 2017: 3 · 2015: 2 · 2014: 4 · 2013: 4 · 2012: 3
- FWCI
- 2.64
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Behavioral Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (MH 25642, MH 47840, MH 00004, P01MH025642)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- amygdala, central amygdala, fear-potentiated startle, fear conditioning, acoustic startle response, reacquisition, learning acquisition, electrolytic lesions, rats
- MeSH terms
- Amygdala, Animals, Arousal, Brain Mapping, Brain Stem, Conditioning, Classical, Efferent Pathways, Fear, Male, Retention, Psychology, Reflex, Startle, Rats, Sprague-Dawley, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review