The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
A selective role for corticosterone in contextual-fear conditioning
Abstract
The contribution of corticosterone to contextual- and auditory-cue fear conditioning was examined. Adrenalectomized rats showed reduced contextual-fear conditioning when tested 24 hr after conditioning; however, neither immediate contextual- nor auditory-cue fear conditioning was impaired. Contextual-fear conditioning in adrenalectomized rats with corticosterone replacement during the 4-day interval separating surgery and conditioning matched the level of controls. Moreover, rats exposed to the context prior to adrenalectomy showed normal long-term contextual-fear conditioning. Corticosterone replacement administered after the conditioning episode also negated the effects of adrenalectomy. Thus, corticosterone's role in fear conditioning is selective: It appears to contribute to the neural processes that support the consolidation of a long-term memory representation of the context.
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“and show parallel biphasic effects upon memory (Pugh et al., 1997).”
From Central effects of stress hormones in health and disease: understanding the protective and damaging effects of stress and stress mediators (2008) · cites this paper as Pugh et al., 1997
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Cites
Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning.
Phillips, R. G., & LeDoux, J. E. (1992) · Behavioral Neuroscience · doi:10.1037/0735-7044.106.2.274 · Cited by 3,292
Spatial localization does not require the presence of local cues
Morris, R. G. M. (1981) · Learning and Motivation · doi:10.1016/0023-9690(81)90020-5 · Cited by 2,699
Modality-Specific Retrograde Amnesia of Fear
Kim, J. J., & Fanselow, M. S. (1992) · Science · doi:10.1126/science.1585183 · Cited by 2,483
Cremer, H., Lange, R., Christoph, A., Plomann, M., Vopper, G., Roes, J., Brown, R. W., Baldwin, S. A., Kraemer, P. J., Scheff, S. W., et al. (1994) · Nature · doi:10.1038/367455a0 · Cited by 1,007
Selective corticosteroid antagonists modulate specific aspects of spatial orientation learning.
Oitzl, M. S., & de Kloet, E. R. (1992) · Behavioral Neuroscience · doi:10.1037//0735-7044.106.1.62 · Cited by 649
Kim, J. J., Rison, R. A., & Fanselow, M. S. (1993) · Behavioral Neuroscience · doi:10.1037/0735-7044.107.6.1093 · Cited by 615
de Kloet, E. R., & Reul, J. M. H. M. (1987) · Psychoneuroendocrinology · doi:10.1016/0306-4530(87)90040-0 · Cited by 595
Selden, N. R. W., Everitt, B. J., Jarrard, L. E., & Robbins, T. W. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90379-3 · Cited by 578
Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAM
Lüthi, A., Laurent, J., Figurovt, A., Mullert, D., & Schachnert, M. (1994) · Nature · doi:10.1038/372777a0 · Cited by 564
Factors governing one-trial contextual conditioning
Fanselow, M. S. (1990) · Animal Learning & Behavior · doi:10.3758/bf03205285 · Cited by 564
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Metadata
- Authors
- Pugh, C. R., Tremblay, D., Fleshner, M., & Rudy, J. W.
- Affiliations
- University of Colorado Boulder (US)
- Venue
- Behavioral Neuroscience
- Published
- 1997-06
- Volume
- 111
- Issue
- 3
- Pages
- 503-511
- ISSN
- 0735-7044 (ISSN-L)
- 1939-0084
- OpenAlex
- W2057143757
- Cited by
- 272
- References
- 38
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 1 · 2022: 3 · 2021: 7 · 2020: 6 · 2019: 6 · 2018: 9 · 2017: 6 · 2016: 8 · 2015: 11 · 2014: 17 · 2013: 10 · 2012: 6
- FWCI
- 5.67
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Behavioral Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01mh049407-03)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Keywords
- corticosterone, contextual fear conditioning, adrenalectomy, corticosterone replacement, memory consolidation, long-term memory, glucocorticoids, rats
- MeSH terms
- Acoustic Stimulation, Adrenalectomy, Animals, Arousal, Association Learning, Conditioning, Classical, Corticosterone, Fear, Female, Male, Mental Recall, Retention, Psychology, Rats
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