Inhibition of ongoing responses following frontal, nonfrontal, and basal ganglia lesions.
Abstract
The authors investigated the role of the frontal lobes and the basal ganglia in the inhibition of ongoing responses. Seventeen patients with frontal lesions (FG), 20 patients with lesions outside the frontal cortex (NFG), 8 patients with lesions to the basal ganglia (BG), and 20 orthopedic controls (OG) performed the stop-signal task that allows the estimation of the time it takes to inhibit an ongoing reaction (stop signal reaction time [SSRT]). The FG and the BG showed significantly longer SSRTs than the OG. Within the FG, patients with right and bilateral lesions showed significantly longer SSRTs than patients with left lesions. Results provide evidence for a role of the frontal lobes and the basal ganglia in the inhibition of ongoing responses.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Patients with damaged basal ganglia are slower to stop their responses than controls.
“In line with these animal findings, patients with damaged basal ganglia are slower to stop their responses than controls (Rieger et al. 2003).”
From Large-scale functional neural network correlates of response inhibition: an fMRI meta-analysis (2017) · cites this paper as Rieger et al. 2003
Basal ganglia lesions impaired stop performance in humans and rodents, while deep-brain stimulation of STN in Parkinson patients improved inhibitory control.
“Lesions to the basal ganglia impaired stop performance for both humans and rodents [26–28], whereas deep-brain stimulation of STN in Parkinson patients enhanced inhibitory control [29].”
From Response inhibition in the stop-signal paradigm (2008) · cites this paper as [27]
The citation lists haven’t been fetched yet
References 84 · Cited by 183
- Authors
- Rieger, M., Gauggel, S., & Burmeister, K.
- Affiliations
- Max Planck Society (DE)
- Philipps University of Marburg (DE)
- Venue
- Neuropsychology
- Published
- 2003
- Volume
- 17
- Issue
- 2
- Pages
- 272-282
- ISSN
- 0894-4105 (ISSN-L)
- 1931-1559
- OpenAlex
- W2918499786
- Cited by
- 183
- References
- 84
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 3 · 2023: 3 · 2022: 1 · 2021: 2 · 2020: 4 · 2019: 5 · 2018: 10 · 2017: 5 · 2016: 7 · 2015: 4 · 2014: 7 · 2013: 18 · 2012: 13
- FWCI
- 4.40
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuropsychology (publishedVersion)
- PubMed (publishedVersion)
- Max Planck Institute for Plasma Physics (submittedVersion)
- Max Planck Digital Library (submittedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- response inhibition, frontal lobe lesions, basal ganglia lesions, stop-signal task, stop-signal reaction time, hemispheric lateralization, executive function
- MeSH terms
- Adult, Aged, Basal Ganglia, Brain Damage, Chronic, Brain Neoplasms, Cerebrovascular Disorders, Female, Frontal Lobe, Humans, Functional Laterality, Male, Middle Aged, Neuropsychological Tests, Postoperative Complications, Psychomotor Performance, Reaction Time, Basal Ganglia Cerebrovascular Disease
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
