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Chronic psychosocial factors and acute physiological responses to laboratory-induced stress in healthy populations: a quantitative review of 30 years of investigations
Abstract
This meta-analysis included 729 studies from 161 articles investigating how acute stress responsivity (including stress reactivity and recovery of hypothalamic-pituitary-adrenal [HPA] axis, autonomic, and cardiovascular systems) changes with various chronic psychosocial exposures (job stress; general life stress; depression or hopelessness; anxiety, neuroticism, or negative affect; hostility, aggression, or Type-A behavior; fatigue, burnout, or exhaustion; positive psychological states or traits) in healthy populations. In either the overall meta-analysis or the methodologically strong subanalysis, positive psychological states or traits were associated with reduced HPA reactivity. Hostility, aggression, or Type-A behavior was associated with increased cardiovascular (heart rate or blood pressure) reactivity, whereas anxiety, neuroticism, or negative affect was associated with decreased cardiovascular reactivity. General life stress and anxiety, neuroticism, or negative affect were associated with poorer cardiovascular recovery. However, regarding the sympathetic nervous system and parasympathetic nervous system, there were no associations between the chronic psychosocial factors and stress reactivity or recovery. The results largely reflect an integrated stress response pattern of hypo- or hyperactivity depending on the specific nature of the psychosocial background.
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“For example, a quantitative review of 30 years of research showed that general life stress was associated with worse cardiovascular (heart rate and blood pressure) recovery from acute stress (Chida and Hamer, 2008).”
From More than a feeling: A unified view of stress measurement for population science (2018) · cites this paper as Chida and Hamer, 2008
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Metadata
- Authors
- Chida, Y., & Hamer, M.
- Affiliations
- University College London (GB)
- ORCID
- Hamer, Mark
- Venue
- Psychological Bulletin
- Published
- 2008
- Volume
- 134
- Issue
- 6
- Pages
- 829-885
- ISSN
- 0033-2909 (ISSN-L)
- 1939-1455
- OpenAlex
- W2048021011
- Cited by
- 667
- References
- 231
- Citations by year
- 2026: 9 · 2025: 27 · 2024: 18 · 2023: 73 · 2022: 26 · 2021: 29 · 2020: 43 · 2019: 43 · 2018: 46 · 2017: 36 · 2016: 43 · 2015: 40 · 2014: 34 · 2013: 38 · 2012: 50
- FWCI
- 16.68
- Type
- journal article
- Language
- en
- Update notices
- correction (2009-08-24)
- Open access
- closed
- Locations
- Psychological Bulletin (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Funders
- Kanae Foundation for the Promotion of Medical Science
- British Heart Foundation
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Keywords
- chronic psychosocial stress, acute stress response, HPA axis reactivity, cardiovascular reactivity, heart rate, blood pressure, stress recovery, hostility, aggression, Type A behavior pattern, anxiety, neuroticism, negative affect, depression, hopelessness, burnout, fatigue, positive psychological traits, sympathetic nervous system, parasympathetic nervous system, occupational stress, life events, integrated stress response
- MeSH terms
- Affect, Blood Pressure, Health Status, Heart Rate, Humans, Hypothalamo-Hypophyseal System, Laboratories, Life Change Events, Pituitary-Adrenal System, Psychology, Psychophysiology, Stress, Physiological, Type A Personality
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