The DOI matches its Crossref record; 127 of the 127 references it cites were found in a registry or an index.
Meta-analysis of the efficacy of psychological and medical treatments for binge-eating disorder
Open accessAbstract
OBJECTIVE: To provide a comprehensive meta-analysis on the efficacy of psychological and medical treatments for binge-eating disorder (BED), including those targeting weight loss. METHOD: Through a systematic search before March 2018, 81 published and unpublished randomized-controlled trials (RCTs), totaling 7,515 individuals with BED (Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition [DSM-IV] and Fifth Edition [DSM-5]), were retrieved and analyzed using random-effect modeling. RESULTS: In RCTs with inactive control groups, psychotherapy, mostly consisting of cognitive-behavioral therapy, showed large-size effects for the reduction of binge-eating episodes and abstinence from binge eating, followed by structured self-help treatment with medium-to-large effects when compared with wait-list. Pharmacotherapy and pharmacological weight loss treatment mostly outperformed pill placebo conditions with small effects on binge-eating outcome. These results were confirmed for the most common treatments of cognitive-behavioral therapy, self-help treatment based on cognitive-behavioral therapy, and lisdexamfetamine. In RCTs with active control groups, there was limited evidence for the superiority of one treatment category or treatment. In a few studies, psychotherapy outperformed behavioral weight loss treatment in short- and long-term binge-eating outcome and led to lower longer-term abstinence than self-help treatment, while combined treatment revealed no additive effect on binge-eating outcome over time. Overall study quality was heterogeneous and the quality of evidence for binge-eating outcome was generally very low. CONCLUSIONS: This comprehensive meta-analysis demonstrated the efficacy of psychotherapy, structured self-help treatment, and pharmacotherapy for patients with BED. More high quality research on treatments for BED is warranted, with a focus on long-term maintenance of therapeutic gains, comparative efficacy, mechanisms through which treatments work, and complex models of care. (PsycINFO Database Record (c) 2018 APA, all rights reserved).
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Abstinence rates were somewhat lower in the current study (29.9%) compared to various RCTs for BED: guided selfhelp CBT-E (31% based on self-report, and 48% based on interviewdata) (Melisse, Berg, et al., 2023a), self-help CBT-ED (36% -46% based on interview-data) (de Zwaan et al., 2017; Hilbert et al., 2019), or inperson CBT-ED (36% -61% based on interview-data) (de Zwaan et al., 2017; Hilbert et”
From Effectiveness of web-based guided self-help cognitive behavioral therapy-enhanced for binge-eating disorder: An implementation study (2024) · cites this paper as Hilbert et al., 2019
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Consistent with convergent findings across CBT-based programs for BED (4), there was no significant differences in BMI across timepoints”
From The acceptability, feasibility, and preliminary efficacy of a supported online self-help treatment program for binge-eating disorder (2023) · cites this paper as [4]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Conducting Meta-Analyses in R with the metafor Package
Viechtbauer, W. (2010) · Journal of Statistical Software · doi:10.18637/jss.v036.i03 · Cited by 20,464
Diagnostic and Statistical Manual of Mental Disorders, 5th ed.
Carter, M. J. (2014) · Therapeutic Recreation Journal · Cited by 15,154
Duval, S., & Tweedie, R. (2000) · Biometrics · doi:10.1111/j.0006-341x.2000.00455.x · Cited by 14,099
Borenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R. (2021) · doi:10.1002/9781119558378 · Cited by 9,799
Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1. The Cochrane Collaboration
Higgins, J., Green, S. R., & Higgins, J. (2008) · Cited by 5,544
A Nonparametric “Trim and Fill” Method of Accounting for Publication Bias in Meta-Analysis
Duval, S., & Tweedie, R. (2000) · Journal of the American Statistical Association · doi:10.1080/01621459.2000.10473905 · Cited by 2,955
Mediators and Mechanisms of Change in Psychotherapy Research
Kazdin, A. E. (2007) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.3.022806.091432 · Cited by 2,504 · cited 1×
“More research is warranted to clarify comparative efficacy and identify through which mechanisms psychotherapies, ideally based on validated maintenance models, work for patients with BED, for example, through mediator analyses, experimental designs, or dismantling studies (Kazdin, 2007).”
BackgroundA Fail-Safe N for Effect Size in Meta-Analysis
Orwin, R. G. (1983) · Journal of Educational Statistics · doi:10.2307/1164923 · Cited by 2,064
How important are the common factors in psychotherapy? An update
Wampold, B. E. (2015) · World Psychiatry · doi:10.1002/wps.20238 · Cited by 1,728 · cited 4×
“This treatment had been conceptualized as a credible psychological placebo controlling for common factors (e.g., therapeutic alliance; Wampold, 2015), while lacking specific ingredients for the treatment of BED (Safer & Hugo, 2006).”
BackgroundResultInfluentialO'Neill, J., Tabish, H., Welch, V., Petticrew, M., Pottie, K., Clarke, M., Evans, T., Pardo Pardo, J., Waters, E., White, H., et al. (2014) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2013.08.005 · Cited by 1,657
Research works printed but not linked: 9
- [1]1. Review, 32, 558-565.
- [4]4. Effective Practice and Organisation of Care (EPOC). (2015). Suggested risk of bias criteria for EPOC reviews. EPOC resources for review authors. Oslo: Norwegian Knowledge Centre for the Health Services. Retrieved from http://www.epoc.cochrane.org/epoc- specific-resources-review-authors (accessed 25 July 2017).
- [75]75. Grilo, C. M., Masheb, R. M., Wilson, G. T., Gueorguieva, R., & White, M. A. (2011). Cognitive-behavioral therapy, behavioral weight loss, and sequential treatment for obese patients with binge-eating disorder: a randomized controlled trial. Journal of Consulting and Clinical Psychology, 79, 675-685.
- [87]87. Le Grange, D., Gorin, A., Dymek, M., & Stone, A. (2002). Does ecological momentary assessment improve cognitive behavioural therapy for binge eating disorder? A pilot study. European Eating Disorders Review, 10, 316-328.
- [101]101. McElroy, S. L., Hudson, J. I., Malhotra, S., Welge, J. A., Nelson, E. B., & Keck, P. E. Jr. (2003b). Citalopram in the treatment of binge-eating disorder: a placebo-controlled trial. Journal of Clinical Psychiatry, 64, 807-813.
- [103]103. McElroy, S. L., Kotwal, R., Guerdjikova, A. I., Welge, J. A., Nelson, E. B., Lake, K. A., . . . Hudson, J. I. (2006). Zonisamide in the treatment of binge eating disorder with obesity: a randomized controlled trial. Journal of Clinical Psychiatry, 67, 1897-1906.
- [104]104. McElroy, S. L., Kotwal, R., Hudson, J. I., Nelson, E. B., & Keck, P. E. (2004). Zonisamide in the treatment of binge-eating disorder: an open-label, prospective trial. Journal of Clinical Psychiatry, 65, 50-56.
- [130]130. White, M. A., & Grilo, C. M. (2013). Bupropion for overweight women with binge-eating disorder: a randomized, double-blind, placebo-controlled trial. Journal of Clinical Psychiatry, 74, 400-406.
- [134]134. Yu, Z., Snyder, J., Stuart, K., Wilburn, J., Pudwill, H., Williams, B., & Cortazzo, K. (2017). A web-based binge eating disorder intervention program reduced eating disorder risks in overweight or obese females-A pilot study. The FASEB Journal, 31, 360-360.
Cited by
Sorted by citations
Treasure, J. L., Duarte, T. A., & Schmidt, U. H. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30059-3 · Cited by 1,110
Leichsenring, F., Steinert, C., Rabung, S., & Ioannidis, J. P. A. (2022) · World Psychiatry · doi:10.1002/wps.20941 · Cited by 485
Treatment of eating disorders: A systematic meta-review of meta-analyses and network meta-analyses
Monteleone, A. M., Pellegrino, F., Croatto, G., Carfagno, M., Hilbert, A., Treasure, J. L., Wade, T. D., Bulik, C. M., Zipfel, S., Hay, P., et al. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104857 · Cited by 326
Self-citationGiel, K. E., Bulik, C. M., Fernandez-Aranda, F., Hay, P., Keski-Rahkonen, A., Schag, K., Schmidt, U., & Zipfel, S. (2022) · Nature Reviews Disease Primers · doi:10.1038/s41572-022-00344-y · Cited by 296
Current approach to eating disorders: a clinical update
Hay, P. (2020) · Internal Medicine Journal · doi:10.1111/imj.14691 · Cited by 266
Metadata
- Authors
- Hilbert, A., Petroff, D., Herpertz, S., Pietrowsky, R., Tuschen-Caffier, B., Vocks, S., & Schmidt, R.
- Affiliations
- European Medicines Agency (NL)
- Corresponding author
- Hilbert, Anja
- Venue
- Journal of Consulting and Clinical Psychology
- Published
- 2019-01
- Volume
- 87
- Issue
- 1
- Pages
- 91-105
- ISSN
- 0022-006X (ISSN-L)
- 1939-2117
- OpenAlex
- W2905971773
- Cited by
- 283
- References
- 127
- Citations by year
- 2026: 22 · 2025: 38 · 2024: 41 · 2023: 49 · 2022: 47 · 2021: 44 · 2020: 29 · 2019: 11
- FWCI
- 3.60
- Type
- journal article
- Language
- en
- Open access
- green
- ul.qucosa.de
- Licence
- other-oa
- Locations
- Journal of Consulting and Clinical Psychology (publishedVersion)
- PubMed (publishedVersion)
- Qucosa (Saxon State and University Library Dresden) (submittedVersion, other-oa)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- binge eating disorder, cognitive behavioral therapy, self-help treatment, pharmacotherapy, lisdexamfetamine, weight loss treatment, treatment efficacy, combined psychotherapy and pharmacotherapy
- MeSH terms
- Adult, Appetite Depressants, Female, Follow-Up Studies, Humans, Male, Obesity, Psychotherapy, Self Care, Self-Help Groups, Weight Loss, Randomized Controlled Trials as Topic, Treatment Outcome, Bariatric Surgery, Binge-Eating Disorder
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
