Patterns of transitions between relapse to and remission from heavy drinking over the first year after outpatient alcohol treatment and their relation to long-term outcomes.
Open accessAbstract
OBJECTIVES: Studying clinical course after alcohol use disorder (AUD) treatment is central to understanding longer-term recovery. This study's two main objectives were to (a) replicate a recent study that identified heterogeneity in patterns of remission from/relapse to heavy drinking during the first year after outpatient treatment in an independent data set and (b) extend these recent findings by testing associations between patterns of remission/relapse and long-term alcohol-related and functioning outcomes. METHOD: Latent profile analyses were conducted using data from Project MATCH (N = 952; M age = 38.9; 72.3% female) and COMBINE (N = 1,383; M age = 44.4; 69.1% male). Transitions between heavy and nonheavy drinking within consecutive 2-week periods over a 1-year posttreatment period were characterized for each participant. From this, latent profiles were identified based on participants' initial 2-week heavy drinking status, the number of observed transitions between 2-week periods of relapse and remission, and the average duration of observed remission/relapse episodes. RESULTS: In both MATCH and COMBINE, we identified six profiles: (a) "continuous remission," 25.3% of COMBINE sample/25.3% of MATCH sample; (b) "transition to remission," 19.6%/9.6%; (c) "few long transitions," 15.9%/33.7%; (d) "many short transitions," 13.2%/13.6%; (e) "transition to relapse," 7.2%/7.1%; and (f) "continuous relapse," 18.8%/10.5%. Profiles 1 and 2 had the best long-term outcomes, Profiles 5 and 6 had the worst, and Profiles 3 and 4 fell between these groups. CONCLUSIONS: That many individuals can remit from heavy drinking following one or more relapses to heavy drinking may be of direct interest to individuals in recovery from AUD. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
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Individuals with severe alcohol use disorder exhibit more psychiatric comorbidities and a higher risk of somatic diseases.
“exhibit more psychiatric comorbidities [26] alongside a higher risk of somatic diseases [27]”
From Psilocybin-assisted therapy for severe alcohol use disorder: protocol for a double-blind, randomized, placebo-controlled, 7-month parallel-group phase II superiority trial (2024) · cites this paper as [26]
Citation [26] is attached to the psychiatric-comorbidities claim; the somatic-disease claim has a separate citation. The Method > Measures section describes assessments of depressive symptoms and mental health, and the Results > COMBINE Latent Profile Analyses section reports poorer mental health for one heavy-drinking profile. Neither passage establishes that people with severe alcohol use disorder have more psychiatric comorbidities; searches for that severity–comorbidity relationship found no such passage. Page numbers were not available in our copy. (LLM, conf=0.73)
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“Moreover, individuals with sAUD are particularly prone to repeated relapse [25] and exhibit more psychiatric comorbidities [26] alongside a higher risk of somatic diseases [27], warranting a prioritization in search of better treatment alternatives.”
Background
- Authors
- Maisto, S. A., Hallgren, K. A., Roos, C. R., Swan, J. E., & Witkiewitz, K.
- Affiliations
- Syracuse University (US)
- University of Washington (US)
- Yale University (US)
- University of New Mexico (US)
- Venue
- Journal of Consulting and Clinical Psychology
- Published
- 2020-12
- Volume
- 88
- Issue
- 12
- Pages
- 1119-1132
- ISSN
- 0022-006X (ISSN-L)
- 1939-2117
- PMC
- PMC7900838
- OpenAlex
- W3114234989
- Cited by
- 21
- References
- 44
- Citations by year
- 2025: 4 · 2024: 7 · 2023: 1 · 2022: 2 · 2021: 7
- FWCI
- 1.79
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Journal of Consulting and Clinical Psychology (publishedVersion, other-oa)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism (R01 AA022328)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Keywords
- alcoholism, heavy drinking, relapse, remission, outpatient alcohol treatment, treatment outcomes, recovery trajectories, Project MATCH, combines, long-term outcomes
- MeSH terms
- Latent Class Analysis, Adult, Alcohol Drinking, Alcoholism, Ambulatory Care, Female, Humans, Male, Middle Aged, Recurrence, Treatment Outcome, Alcohol Abstinence
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