Real-time momentary mood as a predictor of college students’ prescription drug misuse in daily life: Direct links and the moderating role of background mental health.
Open accessAbstract
The present study addressed calls for research to identify real-time predictors of prescription drug misuse (Schepis et al., 2020) by testing young adults' momentary reports of their negative mood and positive mood as predictors of event-level misuse in daily life. We implemented a 28-day ecological momentary assessment (EMA) procedure that collected individuals' mood and other contextual experiences in moments preceding prescription drug misuse. Consistent with models of problematic substance use as a means to reduce negativity (Khantzian, 1997), results from hierarchical generalized linear modeling (HGLM) indicated within-person links between higher than usual negative mood and greater likelihood of prescription misuse in daily life. Contrary to the hypothesis, misuse was also more likely when preceded by elevated positive mood. We found consistent support for the hypothesized between-person effects, with prescription misuse in daily life associated with higher average levels of negative mood, and lower average levels of positive mood, across the reporting period. We further predicted that individuals reporting greater levels of social anxiety, depression, and externalizing symptoms would evidence stronger links between their momentary negative mood and prescription misuse. Partial support for this moderation hypothesis was found, with the positive within-person link between negative mood and prescription misuse significantly stronger among individuals higher (vs. lower) on social anxiety and depression. Results provide support for intricate connections between young adults' momentary mood, mental health symptoms, and prescription drug misuse. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
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Papp et al found that students with higher levels of social anxiety presented a stronger association between negative affect and prescription misuse.
“Papp et al [76] found that students with higher levels of SA presented a stronger association between NA and prescription misuse.”
From Studies of Social Anxiety Using Ambulatory Assessment: Systematic Review (2024) · cites this paper as [76]
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Research works printed but not linked: 1
- Bolger N, & Laurenceau J-P (2013). Intensive longitudinal methods: An introduction to diary and experience sampling research. Guilford Press.
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Hart, A., Reis, D., Prestele, E., & Jacobson, N. C. (2022) · Journal of Medical Internet Research · doi:10.2196/34015 · Cited by 22 · see citing works
“For example, it allows for the recording of mood states before medication is misused [2].”
BackgroundStudies of Social Anxiety Using Ambulatory Assessment: Systematic Review
Fernández-Álvarez, J., Colombo, D., Gómez Penedo, J. M., Pierantonelli, M., Baños, R. M., & Botella, C. (2024) · JMIR Mental Health · doi:10.2196/46593 · Cited by 8 · see citing works
“Finally, Papp et al [76] found that students with higher levels of SA presented a stronger association between NA and prescription misuse.”
BackgroundA network of craving, negative emotions, and cognition in methamphetamine patients
Chen, J., Tian, Y., Li, Y., Zhu, R., Jia, L., Fu, F., Tang, S., Wang, X., Wang, D., & Zhang, X. Y. (2025) · Addictive Behaviors · doi:10.1016/j.addbeh.2025.108248 · Cited by 2 · see citing works
Guðmundsdóttir, B. G., Reynisdóttir, U. E., Sigurvinsdóttir, R., & Sigfúsdóttir, I. D. (2023) · Nordic Psychology · doi:10.1080/19012276.2023.2177712
“Although NMUPD, including stimulants, is predictive of later psychopathology risk (Liu et al., 2020; Schepis & Hakes, 2011), individuals who engage in NMUPS may do so to alleviate psychological distress (e.g. anxiety, depression) (Papp et al., 2021; Sattler & Wiegel, 2013; Teter et al., 2010).”
Background
- Authors
- Papp, L. M., Kouros, C. D., Witt, H. K., Curtin, J. J., Blumenstock, S. M., & Barringer, A.
- Affiliations
- University of Wisconsin–Madison (US)
- Venue
- Experimental and Clinical Psychopharmacology
- Published
- 2022-12
- Volume
- 30
- Issue
- 6
- Pages
- 787-796
- ISSN
- 1064-1297 (ISSN-L)
- 1936-2293
- PMC
- PMC8660934
- OpenAlex
- W3167615994
- Cited by
- 5
- References
- 0
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 1 · 2022: 1
- FWCI
- 0.65
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Experimental and Clinical Psychopharmacology (publishedVersion, other-oa)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- OSF Preprints (OSF Preprints) (submittedVersion)
- Funders
- National Institutes of Health (R01DA042093)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- prescription drug misuse, momentary mood, negative mood, positive mood, young adults, university students, social anxiety, depression, externalizing problems, problematic substance use, within-person effects, between-person effects, moderation
- MeSH terms
- Affect, Humans, Mental Health, Students, Substance-Related Disorders, Young Adult, Prescription Drug Misuse
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