The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Solution structure of the DNA- and RPA-binding domain of the human repair factor XPA
Abstract
The solution structure of the central domain of the human nucleotide excision repair protein XPA, which binds to damaged DNA and replication protein A (RPA), was determined by nuclear magnetic resonance (NMR) spectroscopy. The central domain consists of a zinc-containing subdomain and a C-terminal subdomain. The zinc-containing subdomain has a compact globular structure and is distinct from the zinc-fingers found in transcription factors. The C-terminal subdomain folds into a novel alpha/beta structure with a positively charged superficial cleft. From the NMR spectra of the complexes, DNA and RPA binding surfaces are suggested.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Hilton et al. recently demonstrated that in binding to ds-ssDNA junctions XPA employs a larger DNA-binding domain 102 than was previously described for repair substrates 103, 104.”
From Xeroderma Pigmentosa Group A (XPA), Nucleotide Excision Repair and Regulation by ATR in Response to Ultraviolet Irradiation (2017) · cites this paper as [104]
Citations
Cites
MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures
Kraulis, P. J. (1991) · Journal of Applied Crystallography · doi:10.1107/s0021889891004399 · Cited by 14,011
MOLMOL: A program for display and analysis of macromolecular structures
Koradi, R., Billeter, M., & Wüthrich, K. (1996) · Journal of Molecular Graphics · doi:10.1016/0263-7855(96)00009-4 · Cited by 7,156
AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR
Laskowski, R., Rullmann, J. A., MacArthur, M., Kaptein, R., & Thornton, J. (1996) · Journal of Biomolecular NMR · doi:10.1007/bf00228148 · Cited by 5,502
Nicholls, A. O., Sharp, K. A., & Honig, B. H. (1991) · Proteins Structure Function and Bioinformatics · doi:10.1002/prot.340110407 · Cited by 5,230
Raster3D Version 2.0. A program for photorealistic molecular graphics
Merritt, E. A., & Murphy, M. E. P. (1994) · Acta Crystallographica Section D Biological Crystallography · doi:10.1107/s0907444994006396 · Cited by 2,493
Mammalian DNA nucleotide excision repair reconstituted with purified protein components
Aboussekhra, A., Biggerstaff, M., Shivji, M. K. K., Vilpo, J. A., Moncollin, V., Podust, V. N., Protić, M., Hübscher, U., Egly, J.-M., & Wood, R. D. (1995) · Cell · doi:10.1016/0092-8674(95)90289-9 · Cited by 837
Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA
Bochkarev, A. V., Pfuetzner, R. A., Edwards, A. M., & Frappier, L. (1997) · Nature · doi:10.1038/385176a0 · Cited by 559
Proposed structure for the zinc-binding domains from transcription factor IIIA and related proteins.
Berg, J. M. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.1.99 · Cited by 412
RPA involvement in the damage-recognition and incision steps of nucleotide excision repair
He, Z., Henricksen, L. A., Wold, M. S., & Ingles, C. J. (1995) · Nature · doi:10.1038/374566a0 · Cited by 389
Tanaka, K., Miura, N., Satokata, I., Miyamoto, I., Yoshida, M. C., Satoh, Y., Kondo, S., Yasui, A., Okayama, H., & Okada, Y. (1990) · Nature · doi:10.1038/348073a0 · Cited by 388
Self-citation
Research works printed but not linked: 1
- Blake P.R., 1994, Adv. Biophys. Chem., 4, 1
Cited by
Sorted by citations
Structure, Recognition, and Processing of Cisplatin−DNA Adducts
Jamieson, E. R., & Lippard, S. J. (1999) · Chemical Reviews · doi:10.1021/cr980421n · Cited by 2,953
Molecular mechanism of nucleotide excision repair
de Laat, W. L., Jaspers, N. G. J., & Hoeijmakers, J. H. J. (1999) · Genes & Development · doi:10.1101/gad.13.7.768 · Cited by 1,122
Flexible nets: The roles of intrinsic disorder in protein interaction networks
Dunker, A. K., Cortese, M. S., Romero, P., Iakoucheva, L. M., & Uversky, V. N. (2005) · The FEBS Journal · doi:10.1111/j.1742-4658.2005.04948.x · Cited by 1,122
Bertin, G., & Averbeck, D. (2006) · Biochimie · doi:10.1016/j.biochi.2006.10.001 · Cited by 934
The many faces of the helix-turn-helix domain: Transcription regulation and beyond
Aravind, L., Anantharaman, V., BALAJI, S., Babu, M. M., & IYER, L. (2005) · FEMS Microbiology Reviews · doi:10.1016/j.femsre.2004.12.008 · Cited by 734
Metadata
- Authors
- Ikegami, T., Kuraoka, I., Saijo, M., Kodo, N., Kyogoku, Y., Morikawa, K., Tanaka, K., & Shirakawa, M.
- Affiliations
- Nara Institute of Science and Technology (JP)
- The University of Osaka (JP)
- Institute for Protein Research, The University of Osaka (JP)
- Biomolecular Engineering Research Institute (Japan) (JP)
- Corresponding author
- Shirakawa, Masahiro
- Venue
- Nature Structural & Molecular Biology
- Published
- 1998-08
- Volume
- 5
- Issue
- 8
- Pages
- 701-706
- ISSN
- 1545-9985 (ISSN-L)
- 1545-9993
- DOI
- 10.1038/1400
- OpenAlex
- W2020761966
- Cited by
- 139
- References
- 27
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 3 · 2023: 4 · 2022: 3 · 2021: 2 · 2020: 4 · 2019: 8 · 2018: 5 · 2017: 8 · 2016: 7 · 2015: 4 · 2014: 9 · 2013: 2 · 2012: 2
- FWCI
- 2.44
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nature Structural & Molecular Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA Repair Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Structure and Dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Structural Biology › Enzyme Structure and Function
- Keywords
- XPA, nucleotide excision repair, DNA repair, replication protein A, DNA binding, alpha/beta fold, protein structure, solution structure, protein-DNA complex
- MeSH terms
- Amino Acid Sequence, Binding Sites, DNA Repair, DNA-Binding Proteins, Humans, Metalloproteins, Models, Molecular, Molecular Sequence Data, Protein Conformation, Xeroderma Pigmentosum, Zinc, RNA-Binding Proteins, Sequence Homology, Amino Acid, Nuclear Magnetic Resonance, Biomolecular, Replication Protein A, Xeroderma Pigmentosum Group A Protein
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
