The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Mechanism of Testosterone Action in Erythropoiesis
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In the citing paper
“For example, administration of graded doses of testosterone to healthy young and older men, whose endogenous testosterone production was suppressed by administration of a long-acting gonadotropin releasing hormone agonist, dose dependently increased hemoglobin and hematocrit but did not change EPO levels consistently after 20 weeks even at supraphysiologic doses of testosterone (4).”
From Testosterone induces erythrocytosis via increased erythropoietin and suppressed hepcidin: evidence for a new erythropoietin/hemoglobin set point (2014) · cites this paper as [4]
In the citing paper
“especially in older men, who experience greater increments in hemoglobin and hematocrit in response to testosterone administration than young men (4).”
From Testosterone induces erythrocytosis via increased erythropoietin and suppressed hepcidin: evidence for a new erythropoietin/hemoglobin set point (2014) · cites this paper as [4]
In the citing paper
“In the case of testosterone therapy or supplementation, this new set point appears become established after 3 months of treatment (4,10).”
From Testosterone induces erythrocytosis via increased erythropoietin and suppressed hepcidin: evidence for a new erythropoietin/hemoglobin set point (2014) · cites this paper as [4]
Citations
Cites
Role of the kidney in erythropoiesis
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Studies on Erythropoiesis. III. Factors Controlling Erythropoietin Production
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Self-citationPolycythemic Response in Normal Adult Rats to a Nonprotein Plasma Extract from Anemic Rabbits
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INHIBITION OF ERYTHROPOIESIS BY ESTROGENS
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Presence of Plasma Erythropoietin in Hypoxic Rats with or without Kidney(s) and/or Spleen
MIRAND, E. A., & Prentice, T. C. (1957) · Experimental Biology and Medicine · doi:10.3181/00379727-96-23390 · Cited by 91
Self-citationThe effect of oestrone on normal and castrated male rats
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EFFECT OF SEX AND GONADOTROPIC HORMONES UPON THE BLOOD PICTURE OF THE RAT
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Self-citationHumoral Control of Erythropoietic Activity in Man During and After Altitude Exposure.
REYNAFARJE, C., Ramos, J. F., Faura, J., & Villavicencio, D. (1964) · Experimental Biology and Medicine · doi:10.3181/00379727-116-29331 · Cited by 63
A Plasma Extract with Erythropoietic Activity
Gordon, A. S., Piliero, S. J., Kleinberg, W., & Freedman, H. H. (1954) · Experimental Biology and Medicine · doi:10.3181/00379727-86-21066 · Cited by 62
Self-citation
Research works printed but not linked: 5
- Gordon, A. S., Rec. Prog. Hormone Res., 10, 339 (1954).
- Shahidi, N. T., and Diamond, L. K., J. Dis. Child., 98, 293 (1959).
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Cited by
Sorted by citations
Items 101–144 of 144
Developments and challenges for new and emergent preparations for male hypogonadism treatment
Corona, G., Sparano, C., Rastrelli, G., Vignozzi, L., & Maggi, M. (2023) · Expert Opinion on Investigational Drugs · doi:10.1080/13543784.2023.2276760 · Cited by 4
“Originally, T was demonstrated to increase erythropoietin levels [38], but this finding was later confirmed in some [39] but not all studies [40].”
ResultNutritional supplements in renal failure
Stenzel, K. H. (1977) · The American Journal of Medicine · doi:10.1016/0002-9343(77)90417-x · Cited by 4
Szubartowska, E., Gromysz-Kałkowska, K., & Stȩpień, M. (1991) · Comparative Biochemistry and Physiology Part C Comparative Pharmacology · doi:10.1016/0742-8413(91)90046-v · Cited by 4
Virus-induced Murine Leukemia: Its Inhibition and Suppression by Serum Containing Erythropoietin
Stansly, P. G., & Schiop, P. E. (1966) · Science · doi:10.1126/science.152.3725.1082 · Cited by 4
Majluf‐Cruz, A., Hurtado, R., Vargas-Vorácková, F., & Labardini-Méndez, J. R. (1999) · European Journal Of Haematology · doi:10.1111/j.1600-0609.1999.tb01749.x · Cited by 4
Čeponis, J., Wang, C., Swerdloff, R. S., & Liu, P. Y. (2017) · Endocrinology · doi:10.1007/978-3-319-29456-8_11-1 · Cited by 3
Erythropoietin and Erythropoiesis
Gurney, C. W. (1969) · Vitamins and hormones · doi:10.1016/s0083-6729(08)60778-5 · Cited by 3
Morpurgo, B., Gvaryahu, G., & Robinzon, B. (1992) · Copeia · doi:10.2307/1446632 · Cited by 3
Čeponis, J., Wang, C., Swerdloff, R. S., & Liu, P. Y. (2017) · Endocrinology · doi:10.1007/978-3-319-44441-3_11 · Cited by 3
Regulation of Extrarenal Erythropoietin Production
Fried, W. I. (1989) · Advances in experimental medicine and biology · doi:10.1007/978-1-4613-0623-8_6 · Cited by 3
Peschle, C., Barba, P., Cillo, C., Magli, M. C., Migliaccio, G., Pizzella, F., & RAPPAPORT, I. (1979) · Life Sciences · doi:10.1016/0024-3205(79)90053-5 · Cited by 3
Recent Advances in Erythropoietin Physiology
Peschle, C., Magli, M. C., Cillo, C., Lettieri, F., Pizzella, F., Migliaccio, G., Soricelli, A., Scala, G., Mastroberardino, G., & Sasso, G. F. (1978) · Springer eBooks · doi:10.1007/978-1-4612-6301-2_35 · Cited by 3
Murphy, G. P., MIRAND, E. A., Kenny, G. M., Niemat, S., & Staubitz, W. J. (1970) · The Journal of Urology · doi:10.1016/s0022-5347(17)62028-7 · Cited by 3
Self-citationGurney, C. W. (1968) · Advances in metabolic disorders · doi:10.1016/b978-1-4831-9943-6.50014-1 · Cited by 3
Hypoerythropoietinemia and Anemia
Frenkel, E. P. (1970) · Archives of Internal Medicine · doi:10.1001/archinte.125.6.1050 · Cited by 2
Effect of methenolone acetate on erythropoietin responsive cells in rat bone marrow
Mori, M., Chiba, S., Suzuki, S., Kosaka, K., Miura, Y., & Takaku, F. (1974) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(74)90202-2 · Cited by 2
Fredrickson, T. N., & Goetinck, P. F. (1973) · Elsevier eBooks · doi:10.1016/b978-0-12-453801-6.50013-7 · Cited by 2
Naets, J. P. (1969) · Elsevier eBooks · doi:10.1016/b978-1-4832-2826-6.50011-6 · Cited by 2
Gromysz-Kałkowska, K., Szubartowska, E., & Kaczanowska, E. (1989) · Comparative Biochemistry and Physiology Part C Comparative Pharmacology · doi:10.1016/0742-8413(89)90208-9 · Cited by 2
Studies on Hemopoietic Stem Cells in Mice Treated with Testosterone Propionate and Anticancer Drugs
Bogliolo, G. V., Massa, G., Sobrero, A. F., & Pannacciulli, I. M. (1982) · Tumori Journal · doi:10.1177/030089168206800401 · Cited by 2
Einflüsse der Androgene auf Organe außerhalb der Genitalsphäre und des Endokriniums
Voss, H. E. V. (1973) · Springer eBooks · doi:10.1007/978-3-642-80666-7_9 · Cited by 2
In Vitro Modulation of Human Erythropoiesis by Lymphocyte-Rich Fractions of Blood
Zanjani, E. D., Nomdedeu, B., Rinehart, J. J., Gormus, B. J., & Kaplan, M. E. (1978) · Springer eBooks · doi:10.1007/978-1-4612-6301-2_3 · Cited by 2
Rosenfeld, J. B. (1977) · Pharmacology & Therapeutics Part C Clinical Pharmacology and Therapeutics · doi:10.1016/s0362-5486(77)80012-5 · Cited by 1
Wang, L., Zhang, H., Yang, R., Luo, Y., & Cao, X. (2022) · Biology Bulletin · doi:10.1134/s1062359022050120 · Cited by 1
“Sex differences of RBC parameters were observed at 3-21- week-old, it might be that testosterone activates erythropoiesis by promoting erythropoietin production (Mirand et al., 1965).”
BackgroundNeumann, E., Honetz, N., & Wurm, B. (1974) · Annals of Hematology · doi:10.1007/bf01633672 · Cited by 1
The effect of central nervous system stimulation on plasma erythropoietin levels in rhesus monkeys
MIRAND, E. A., Murphy, G. P., & Bernardis, L. L. (1967) · Cellular and Molecular Life Sciences · doi:10.1007/bf02137983 · Cited by 1
Self-citationInhibition of erythropoietin production by cyproterone acetate
Harvey, S. R., MIRAND, E. A., & Murphy, G. P. (1973) · Urology · doi:10.1016/0090-4295(73)90597-9 · Cited by 1
Self-citationMcDonald, T. P. (1968) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1968.tb15175.x · Cited by 1
Alexanian, R., Nadell, J., & Alfrey, C. P. (2016)
Effect of Testosterone Treatment and Hypophysectomy on the Leucocyte Count in Irradiated Rats
Robinson, E., & Growers, I. (1968) · Acta Radiologica Therapy Physics Biology · doi:10.3109/02841866809133208
Effect of hypothalamic lesions on erythropoietin production in weanling and adult rats
MIRAND, E. A., & Bernardis, L. L. (1967) · Cellular and Molecular Life Sciences · doi:10.1007/bf02144192
Self-citationEffects of Testosterone and Erythropoietin on Erythroid Colony Formation in
Moriyama, Y., & Fisher, J. W. (2016)
Koller, F., Duckert, F., Kappert, A., Schmutzler, R., Schoop, W., Vollmar, J., & Widmer, L. (1971) · Verhandlungen der Deutschen Gesellschaft für Innere Medizin · doi:10.1007/978-3-642-85466-8_20
ROLE OF ERYTHROPOIETIN IN ERYTHROPOIESIS
MIRAND, E. A. (1972) · Elsevier eBooks · doi:10.1016/b978-0-12-293060-7.50013-x
Self-citationPolycythemia: a mystery solved by history
Kalal, C. R., Patel, A., Wagh, A., Joshi, H., Jain, S. S., Surude, R. G., Bhatia, S. J., & Bhatt, C. B. (2020) · International Journal of Research in Medical Sciences · doi:10.18203/2320-6012.ijrms20204266
“Historical studies in preclinical models have suggested that testosterone does induce a motivating factor for erythropoiesis, which was measured by a bioassay employing a polycythemia mouse model in these studies.(6) But, human studies haven’t provided clear evidence that testosterone stimulates EPO secretion.”
BackgroundMethodKrantz, S. B., & Gräber, S. E. (1974) · Elsevier eBooks · doi:10.1016/b978-0-12-595705-2.50022-7
Szubartowska, E., Gromysz-Kałkowska, K., Kaczanowska, E., & Wójcik, K. (1989) · Comparative Biochemistry and Physiology Part C Comparative Pharmacology · doi:10.1016/0742-8413(89)90016-9
Gromysz-Kałkowska, K., & Szubartowska, E. (1992) · Comparative Biochemistry and Physiology Part C Comparative Pharmacology · doi:10.1016/0742-8413(92)90258-9
Al-Obaidi, W. M. L. (2023) · Journal of the faculty of Education · doi:10.60037/edu.v1i15.1202
“Testosterone is steroid hormone one the important androgens group increased during the injured with PCOs as well as the research illustration it is important role as a regulator of erythropoiesis process human [8,9] .”
BackgroundEldeify, A., Ali, A. O., Fawaz, M. M., & Mohamed, A. E. A. (2023) · SVU- International Journal of Veterinary Sciences · doi:10.21608/svu.2023.231385.1292
Ateş, B. Ö., Ayaroğlu, P., & Cöngöloğlu, M. A. (2025) · International Journal of Developmental Neuroscience · doi:10.1002/jdn.70058
Čeponis, J., Wang, C., Swerdloff, R., & Liu, P. Y. (2026) · Endocrinology · doi:10.1007/978-3-319-29456-8_11-2
The Control of Red Cell Production
Gurney, C. W. (1970) · Springer eBooks · doi:10.1007/978-1-4684-7873-0_1
Asbell (1996) · doi:10.1002/(sici)1097-0045(199610)29:4
Metadata
- Authors
- MIRAND, E. A., GORDON, A. S., & WENIG, J.
- Affiliations
- Roswell Park Comprehensive Cancer Center (US)
- New York University (US)
- Venue
- Nature
- Published
- 1965-04
- Volume
- 206
- Issue
- 4981
- Pages
- 270-272
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2095110446
- Cited by
- 145
- References
- 27
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 7 · 2022: 1 · 2021: 1 · 2020: 7 · 2019: 1 · 2018: 3 · 2017: 4 · 2016: 2 · 2015: 1 · 2013: 2 · 2012: 3
- FWCI
- 15.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Hematology › Erythropoietin and Anemia Treatment
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
- Keywords
- testosterone, erythropoiesis, erythropoietin, androgen action
- MeSH terms
- Animals, Blood, Erythropoiesis, Iron, Iron Isotopes, Rabbits, Rodentia, Testosterone, Mice, Rats, In Vitro Techniques
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