Do general anaesthetics act by competitive binding to specific receptors?
Franks, N. P., Lieb, W. R.·1984·Nature
DOI 10.1038/310599a0
Cited by (574)
Items 401–500 of 574
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- Do anesthetics act by competitive binding to specific receptors? Phase transition of firefly luciferase1Reported at the Fifth International Conference on the Cellular and Molecular Mechanisms of Anaesthesia, held in Calgary, June 1997.1Issaku Ueda, Atsuya Suzuki, Hiroshi Kamaya · 1998 · Toxicology Letters
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- New Observations on the Mechanism of Pressure-Anesthetic InteractionsE. B. Smith, F. Bowser‐Riley, Stephen R. Daniels · 1986 · Springer eBooks
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- The role of electrochemistry in solving the mystery of the relationship between molecular structure and anaesthetic potencyGabriele Melegari, Anu Gupta, Camilla Ferrari, Neha Kumari, Suryakant Mishra, Enrico Giuliani, Alberto Barbieri, Claudio Fontanesi · 2025 · Current Opinion in Electrochemistry
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- Chapter 41 Cholinergic agents in clinical anaesthesiologyLars Wiklund, Per Hartvig · 1990 · Progress in brain research
- Drug design: the present and the futureM. S. Tute · 1995 · Advances in Drug Research
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- Correspondence2002 · Hospital Medicine
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