News in Brief

Drug Delivery with Carbon Nanotubes for In vivo Cancer Treatment

Liu, Z., Chen, K., Davis, C. R., Sherlock, S. P., Cao, Q., Chen, X. S., & Dai, H. (2008) · Cancer Research · doi:10.1158/0008-5472.can-08-1468 · Cited by 1,349 · see citing works

Nanoparticle-Aptamer Bioconjugates

Farokhzad, O. C., Jon, S., Khademhosseini, A., Tran, T.-N., LaVan, D. A., & Langer, R. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-2550 · Cited by 897 · see citing works

Biomaterials in Drug Delivery and Tissue Engineering: One Laboratory's Experience

Langer, R. (1999) · Accounts of Chemical Research · doi:10.1021/ar9800993 · Cited by 751 · see citing works

Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles

Singh, A. P., Biswas, A., Shukla, A., & Maiti, P. (2019) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-019-0068-3 · Cited by 645 · see citing works

Active Nanodiamond Hydrogels for Chemotherapeutic Delivery

Huang, H., Pierstorff, E. D., O̅sawa, E., & Ho, D. (2007) · Nano Letters · doi:10.1021/nl071521o · Cited by 557 · see citing works

Enzyme Encapsulation in Layer-by-Layer Engineered Polymer Multilayer Capsules

Caruso, F. S., Trau, D., Möhwald, H., et al. (2000) · Langmuir · doi:10.1021/la991161n · Cited by 532 · see citing works

Hydrophobic Interaction and Hydrogen Bonding Cooperatively Confer a Vancomycin Hydrogel: A Potential Candidate for Biomaterials

Xing, B., Yu, C., Chow, K., et al. (2002) · Journal of the American Chemical Society · doi:10.1021/ja028539f · Cited by 408 · see citing works

Targeted Delivery of Gemcitabine to Pancreatic Adenocarcinoma Using Cetuximab as a Targeting Agent

Patra, C. R., Bhattacharya, R., Wang, E., Katarya, A., Lau, J. S., Dutta, S. K., Muders, M. H., Wang, S., Buhrow, S. A., Safgren, S. L., et al. (2008) · Cancer Research · doi:10.1158/0008-5472.can-07-6102 · Cited by 372 · see citing works

Enhanced antiproliferative activity of transferrin-conjugated paclitaxel-loaded nanoparticles is mediated via sustained intracellular drug retention

Sahoo, S. K., & Labhasetwar, V. (2005) · Molecular Pharmaceutics · doi:10.1021/mp050032z · Cited by 340 · see citing works

How Autocatalysis Accelerates Drug Release from PLGA-Based Microparticles: A Quantitative Treatment

Siepmann, J., Elkharraz, K., Siepmann, F., & Klose, D. (2005) · Biomacromolecules · doi:10.1021/bm050228k · Cited by 308 · see citing works

Dendritic Molecular Capsules for Hydrophobic Compounds

Morgan, M. T., Carnahan, M. A., Immoos, C. E., Ribeiro, A. A., Finkelstein, S., Lee, S. J., & Grinstaff, M. W. (2003) · Journal of the American Chemical Society · doi:10.1021/ja0347383 · Cited by 252 · see citing works

Lipid Bilayers Driven to a Wrong Lane in Molecular Dynamics Simulations by Subtle Changes in Long-Range Electrostatic Interactions

Patra, M., Karttunen, M., Hyvönen, M., et al. (2004) · The Journal of Physical Chemistry B · doi:10.1021/jp031281a · Cited by 195 · see citing works

Polymeric Nanoparticle Preparation that Eradicates Tumors

McCarthy, J. R., Perez, J. M., Brückner, C., & Weissleder, R. (2005) · Nano Letters · doi:10.1021/nl0519229 · Cited by 192 · see citing works

Determination of the Bioavailability of Biotin Conjugated onto Shell Cross-Linked (SCK) Nanoparticles

Qi, K., Ma, Q., Remsen, E. E., Clark, C. G., & Wooley, K. L. (2004) · Journal of the American Chemical Society · doi:10.1021/ja039647k · Cited by 182 · see citing works

Microfluidic System for Studying the Interaction of Nanoparticles and Microparticles with Cells

Farokhzad, O. C., Khademhosseini, A., Jon, S., Hermmann, A., Cheng, J., Chin, C. D., Kiselyuk, A., Teply, B. A., Eng, G. M., & Langer, R. (2005) · Analytical Chemistry · doi:10.1021/ac050312q · Cited by 175 · see citing works

Microencapsulation of Uncharged Low Molecular Weight Organic Materials by Polyelectrolyte Multilayer Self-Assembly

Caruso, F., Yang, W., Trau, D., & Renneberg, R. (2000) · Langmuir · doi:10.1021/la000401s · Cited by 163 · see citing works

Application of thermally responsive polypeptides directed against c-Myc transcriptional function for cancer therapy

Bidwell, G. L., & Raucher, D. (2005) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-04-0253 · Cited by 145 · see citing works

Carbonated calcium phosphates are suitable pH-stabilising fillers for biodegradable polyesters

Schiller, C., & Epple, M. (2003) · Biomaterials · doi:10.1016/s0142-9612(02)00634-8 · Cited by 133 · see citing works

Chymotrypsin Responsive Hydrogel: Application of a Disulfide Exchange Protocol for the Preparation of Methacrylamide Containing Peptides

Plunkett, K. N., Berkowski, K. L., & Moore, J. S. (2005) · Biomacromolecules · doi:10.1021/bm049349v · Cited by 125 · see citing works

In-Situ AFM Studies of the Phase-Transition Behavior of Single Thermoresponsive Hydrogel Particles

Wiedemair, J., Serpe, M. J., Kim, J., et al. (2006) · Langmuir · doi:10.1021/la061288u · Cited by 125 · see citing works

Synthesis of Collagen-like Peptide Polymers by Native Chemical Ligation

Paramonov, S. E., Gauba, V., & Hartgerink, J. D. (2005) · Macromolecules · doi:10.1021/ma0514065 · Cited by 124 · see citing works

RB -mediated suppression of spontaneous multiple neuroendocrine neoplasia and lung metastases in Rb +/− mice

Nikitin, A. Y., Juarez-Perez, M. I., Li, S., Huang, L., & Lee, W. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.7.3916 · Cited by 118 · see citing works

Anti-neovascular therapy using novel peptides homing to angiogenic vessels

Oku, N., Asai, T., Watanabe, K., Kuromi, K., Nagatsuka, M., Kurohane, K., Kikkawa, H., Ogino, K., Tanaka, M., Ishikawa, D., et al. (2002) · Oncogene · doi:10.1038/sj.onc.1205347 · Cited by 116 · see citing works

Asymmetrical Flow Field-Flow Fractionation and Multiangle Light Scattering for Analysis of Gelatin Nanoparticle Drug Carrier Systems

Fraunhofer, W., Winter, G., & Coester, C. (2004) · Analytical Chemistry · doi:10.1021/ac0353031 · Cited by 115 · see citing works

Intravenous liposomal delivery of the snake venom disintegrin contortrostatin limits breast cancer progression

Swenson, S. D., Costa, F. K., Minea, R. O., Sherwìn, R. P., Ernst, W. A., Fujii, G., Yang, D., & Markland, F. S. (2004) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.499.3.4 · Cited by 112 · see citing works

Synthesis of Thermosensitive Water-Soluble Polystyrenics with Pendant Methoxyoligo(ethylene glycol) Groups by Nitroxide-Mediated Radical Polymerization

Zhao, B., Li, D., Hua, F., et al. (2005) · Macromolecules · doi:10.1021/ma0514572 · Cited by 103 · see citing works

Microcapsules from Self-Assembled Colloidal Particles Using Aqueous Phase-Separated Polymer Solutions

Poortinga, A. T. (2008) · Langmuir · doi:10.1021/la703441e · Cited by 102 · see citing works

Delivery of Acid Sphingomyelinase in Normal and Niemann-Pick Disease Mice Using Intercellular Adhesion Molecule-1-Targeted Polymer Nanocarriers

Garnacho, C., Dhami, R., Simone, E. A., Dziubla, T. D., Leferovich, J. M., Schuchman, E. H., Muzykantov, V. R., & Muro, S. (2008) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.107.133298 · Cited by 100 · see citing works

Determination of the Encapsulation Efficiency of Individual Vesicles Using Single-Vesicle Photolysis and Confocal Single-Molecule Detection

Sun, B., & Chiu, D. T.-Y. (2005) · Analytical Chemistry · doi:10.1021/ac048439n · Cited by 98 · see citing works

Electron-Beam Surface-Patterned Poly(ethylene glycol) Microhydrogels

Krsko, P., Sukhishvili, S. A., Mansfield, M. L., et al. (2003) · Langmuir · doi:10.1021/la034157r · Cited by 93 · see citing works

Surface Engineering of Poly(lactic acid) by Entrapment of Modifying Species

Quirk, R. A., Davies, M. C., Tendler, S. J. B., & Shakesheff, K. M. (2000) · Macromolecules · doi:10.1021/ma9916133 · Cited by 88 · see citing works

Synthesis and Evaluation of Novel Dendrimers with a Hydrophilic Interior as Nanocarriers for Drug Delivery

Dhanikula, R. S., & Hildgen, P. (2005) · Bioconjugate Chemistry · doi:10.1021/bc050184c · Cited by 85 · see citing works

Temperature-Induced Self-Association of Doubly Thermosensitive Diblock Copolymers with Pendant Methoxytris(oxyethylene) Groups in Dilute Aqueous Solutions

Hua, F., Jiang, X., & Zhao, B. (2006) · Macromolecules · doi:10.1021/ma060586v · Cited by 82 · see citing works

Synthesis and Characterisation of a Degradable Poly(lactic acid)−Poly(ethylene glycol) Copolymer with Biotinylated End Groups

Salem, A. K., Cannizzaro, S. M., Davies, M. C., Tendler, S. J. B., Roberts, C. J., Williams, P. M., & Shakesheff, K. M. (2001) · Biomacromolecules · doi:10.1021/bm010030+ · Cited by 81 · see citing works

Microdroplet Dissolution into a Second-Phase Solvent Using a Micropipet Technique: Test of the Epstein−Plesset Model for an Aniline−Water System

Duncan, P. B., & Needham, D. (2006) · Langmuir · doi:10.1021/la053314e · Cited by 81 · see citing works

Encapsulation and Sustained Release of a Model Drug, Indomethacin, Using CO2-Based Microencapsulation

Liu, H., Finn, N., & Yates, M. Z. (2004) · Langmuir · doi:10.1021/la047934b · Cited by 81 · see citing works

Fabrication of a Reversible Protein Array Directly from Cell Lysate Using a Stimuli-Responsive Polypeptide

Nath, N., & Chilkoti, A. (2003) · Analytical Chemistry · doi:10.1021/ac0261855 · Cited by 77 · see citing works

Alteration of Genomic Responses to Doxorubicin and Prevention of MDR in Breast Cancer Cells by a Polymer Excipient: Pluronic P85

Batrakova, E. V., Kelly, D. L., Li, S., et al. (2005) · Molecular Pharmaceutics · doi:10.1021/mp050050g · Cited by 75 · see citing works

Pulses of Fast Electrons as a Tool To Synthesize Poly(acrylic acid) Nanogels. Intramolecular Cross-Linking of Linear Polymer Chains in Additive-Free Aqueous Solution

Kadłubowski, S., Grobelny, J., Olejniczak, W., et al. (2003) · Macromolecules · doi:10.1021/ma021628s · Cited by 74 · see citing works

Synthesis of Functionalized Polyethers by Ring-Opening Metathesis Polymerization of Unsaturated Crown Ethers

Maynard, H. D., & Grubbs, R. H. (1999) · Macromolecules · doi:10.1021/ma990749y · Cited by 69 · see citing works

In vivocharacterization of a polymeric nanoparticle platform with potential oral drug delivery capabilities

Bisht, S., Feldmann, G., Koorstra, J.-B. M., Mullendore, M. E., Alvarez, H., Karikari, C. A., Rudek, M. A., Lee, C. K., Maitra, A., & Maitra, A. (2008) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-08-0476 · Cited by 68 · see citing works

Nuclear Localization Signal-Targeted Poly(ethylene glycol) Conjugates as Potential Carriers and Nuclear Localizing Agents for Carboplatin Analogues

Aronov, O., Horowitz, A. T., Gabizon, A., et al. (2004) · Bioconjugate Chemistry · doi:10.1021/bc0499331 · Cited by 56 · see citing works

Free Pyrene Probes in Gel and Fluid Membranes: Perspective through Atomistic Simulations

Čurdová, J., Čapková, P., Plášek, J., Repáková, J., & Vattulainen, I. (2007) · The Journal of Physical Chemistry B · doi:10.1021/jp065956w · Cited by 54 · see citing works

Self-Exploding Lipid-Coated Microgels

Geest, B. G. D., Stubbe, B. G., Jonas, A. M., et al. (2005) · Biomacromolecules · doi:10.1021/bm0507296 · Cited by 48 · see citing works

Synthesis and Characterization of PEG-Based Ether−Anhydride Terpolymers: Novel Polymers for Controlled Drug Delivery

Fu, J., Fiegel, J., & Hanes, J. S. (2004) · Macromolecules · doi:10.1021/ma049853s · Cited by 47 · see citing works

Characterization of Nanostructure of Stimuli-Responsive Polymeric Composite Membranes

Zhang, K., Huang, H., Yang, G., et al. (2004) · Biomacromolecules · doi:10.1021/bm034458f · Cited by 46 · see citing works

Synthesis, Characterization and Evaluation of Antimicrobial, Antioxidant & Anticancer Activities of Copper Doped Zinc Oxide Nanoparticles

Rishikesan, S., & Basha, M. A. M. (2020) · Acta chimica slovenica · doi:10.17344/acsi.2019.5379 · Cited by 45 · see citing works

Method for Quantifying the PEGylation of Gelatin Nanoparticle Drug Carrier Systems Using Asymmetrical Flow Field-Flow Fractionation and Refractive Index Detection

Zillies, J. C., Zwiorek, K., Winter, G., & Coester, C. (2007) · Analytical Chemistry · doi:10.1021/ac062135e · Cited by 45 · see citing works

Responsive Hybrid Hydrogels with Volume Transitions Modulated by a Titin Immunoglobulin Module

Chen, L., Kopec̆ek, J., & Stewart, R. J. (2000) · Bioconjugate Chemistry · doi:10.1021/bc000046h · Cited by 45 · see citing works

Layered Polyelectrolyte−Silica Coating for Nanocapsules

Sun, B., Mutch, S. A., Lorenz, R. M., et al. (2005) · Langmuir · doi:10.1021/la0513297 · Cited by 42 · see citing works

Single-Step Process to Produce Surface-Functionalized Polymeric Nanoparticles

Sussman, E. M., Clarke, M. B., & Shastri, V. P. (2007) · Langmuir · doi:10.1021/la701997x · Cited by 33 · see citing works

Influence of Ancillary Binding and Nonspecific Adsorption on Bioresponsive Hydrogel Microlenses

Kim, J., Singh, N., & Lyon, L. A. (2007) · Biomacromolecules · doi:10.1021/bm070005p · Cited by 31 · see citing works

Characterization of Surface-Modified Nanoparticles for in Vivo Biointeraction. A Sedimentation Field Flow Fractionation Study

Andersson, M., Fromell, K., Gullberg, E., et al. (2005) · Analytical Chemistry · doi:10.1021/ac050631h · Cited by 27 · see citing works

Visco-Elastic-Plastic Properties of Suture Fibers Made of PLA-PCL

Vieira, A. C., Medeiros, R. D., Guedes, R. M., Marques, A. T., & Tita, V. (2012) · Materials science forum · doi:10.4028/www.scientific.net/msf.730-732.56 · Cited by 25 · see citing works

Monte Carlo Simulations of Nanogels Formation by Intramolecular Recombination of Radicals on Polymer Chain. Dispersive Kinetics Controlled by Chain Dynamics

Jeszka, J. K., Kadłubowski, S., & Ulański, P. (2005) · Macromolecules · doi:10.1021/ma0518757 · Cited by 24 · see citing works

Encapsulation of Submicrometer-Sized 2-Methoxyestradiol Crystals into Polymer Multilayer Capsules for Biological Applications

Shi, X., Wang, S. H., Chen, X., et al. (2006) · Molecular Pharmaceutics · doi:10.1021/mp050078s · Cited by 21 · see citing works

Fast Initiation of Chemical Reactions with Laser-Induced Breakdown of a Nanoscale Partition

Sun, B., Lim, D. S. W., Kuo, J. S., et al. (2004) · Langmuir · doi:10.1021/la048444m · Cited by 15 · see citing works

Development of a Carbon Dioxide-Based Microencapsulation Technique for Aqueous and Ethanol-Based Latexes

Liu, H., & Yates, M. Z. (2002) · Langmuir · doi:10.1021/la0257945 · Cited by 11 · see citing works

Microfabricated Microneedles for Transdermal Drug Delivery

Prausnitz, M. R., Ackley, D. E., & Gyory, J. R. (2002) · CRC Press eBooks · doi:10.1201/9780203910337-45 · Cited by 11 · see citing works

A Quantitative Method for the Determination of Amphiphilic Drug Release Kinetics from Nanoparticles Using a Langmuir Balance

Lamprecht, A., Saulnier, P., Boury, F., Passirani, C., Proust, J. E., & Benoît, J. (2002) · Analytical Chemistry · doi:10.1021/ac025581k · Cited by 9 · see citing works

Iron oxide and gold nanoparticles in cancer therapy

Gotman, I. Y., Psakhie, S. G., Lozhkomoev, A. S., et al. (2016) · AIP conference proceedings · doi:10.1063/1.4960239 · Cited by 7 · see citing works

Light-Directed Movement of Polymer Microstructures

Northen, T. R., & Woodbury, N. W. (2005) · Langmuir · doi:10.1021/la047566b · Cited by 6 · see citing works

The Nai Fellow Profile: An Interview With Dr. Robert S. Langer

Langer, R., & Macuare, K. A. (2016) · Technology & Innovation · doi:10.21300/18.2-3.2016.219 · Cited by 2 · see citing works

An in-depth overview of controlled drug delivery systems

Hamzy, I. A., Alqhoson, A. I., Aljarbou, A. M., et al. (2022) · International Journal of Health Sciences · doi:10.53730/ijhs.v6ns10.15096 · Cited by 2 · see citing works

pH-triggered drug release from a nanosized metal–organic framework/graphene oxide composite

Sultana, N., Nizami, M. Z. I., Obata, S., & Nishina, Y. (2024) · Carbon Reports · doi:10.7209/carbon.040104 · Cited by 2 · see citing works

Airway local endoscopic pharmacological treatment; current applications and future concepts

Zarogoulidis, P., Kosmidis, C. S., Sapalidis, K. G., et al. (2022) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2701036 · Cited by 1 · see citing works

Potential therapeutic applications of targeting signal-transducing adaptor protein-2 in autoimmune diseases

Sasaki, Y., Kawahara, S., Sekine, Y., et al. (2023) · Exploration of Immunology · doi:10.37349/ei.2023.00125 · Cited by 1 · see citing works

Potential of targeting signal-transducing adaptor protein-2 in cancer therapeutic applications

Maemoto, T., Sasaki, Y., Okuyama, F., et al. (2024) · Exploration of Targeted Anti-tumor Therapy · doi:10.37349/etat.2024.00216 · Cited by 1 · see citing works

Advancements in macromolecular complexity and their implications for drug delivery systems

Hamzy, I. A., Alqhoson, A. I., Aljarbou, A. M., & Alhajri, M. A. (2018) · International Journal of Health Sciences · doi:10.53730/ijhs.v2ns1.15093 · Cited by 1 · see citing works

Plant Mediated Synthesis Cu-Ag-Ru Trimetallic Nanoparticles Using Andrographis Paniculata extract: Antibacterial, Anticancer and Photocatalytic Activities

Radhakrishnan, R., & Subramanium, S. (2024) · Oriental Journal Of Chemistry · doi:10.13005/ojc/400635 · Cited by 1 · see citing works

Stability of polyelectrolytes complexes nanoparticles based on chitosan – poly-2-acrylamido-2-methylprophane sulfonic acid in dilute sodium chloride solution

Wibowo, A., Jatmiko, A. T. P., Ananda, M. B., et al. (2021) · AIP conference proceedings · doi:10.1063/5.0062177

Emerging Frontiers in Formulation Development: Trends in Novel Drug-Delivery Systems for Enhanced Therapeutic Outcomes

Donthula, K. K., Thakkalapally, S., Rao, G. K., et al. (2026) · Journal of Drug Delivery and Therapeutics · doi:10.22270/jddt.v16i2.7550

Novel Cu(II) complexes bearing N,O-donor heteroaromatic ligands as potential anticancer drugs : a redox-active metallic core

Aparicio, J. P. (2019) · doi:10.70675/04c7447dzd372z4a28zbeb2z0ef393ef2da0

Nanotechnology-Driven Drug Delivery System: Recent Advances, Applications and Future Perspectives

Chandola, M., Dhaundhiyal, K., Ojha, A., et al. (2026) · Journal of Drug Delivery and Therapeutics · doi:10.22270/jddt.v16i4.7694

Nanotherapeutics in the treatment of cancer: transforming cancer care

Rad, M. K., Razani, E., & Bashash, D. (2026) · European Journal of Cancer Care · doi:10.48130/ejcc-0026-0007

Integration of photobiomodulation and nanomedicine: Recent advances and possible mechanisms for non-photoactive nanoparticles

Arshad, K., Golovynska, I., Golovynskyi, S., Qu, J., & Ohulchanskyy, T. Y. (2026) · PhotoniX Life · doi:10.3724/pxlife.2026-0006

Titan's Astrobiology

Raulin, F., McKay, C. P., Lunine, J. I., & Owen, T. (2009) · Springer eBooks · doi:10.1007/978-1-4020-9215-2_9 · Cited by 18 · see citing works

Question 2: Why an Astrobiological Study of Titan Will Help Us Understand the Origin of Life

Raulin, F. (2007) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-007-9077-2 · Cited by 15 · see citing works

Mars, Earth and Titan: Origins of Atmospheres

Owen, T. (2010) · EGU General Assembly Conference Abstracts

Extreme environments on Earth as analogues for life on other planets: astrobiology.

Gómez, F., Barták, M., & Bell, E. M. (2012) · CABI eBooks · doi:10.1079/9781845938147.0522 · Cited by 4 · see citing works

Early Atmospheres on Terrestrial Planets(Mars and Titan, International Symposium on Origins of Life and Astrobiology)

Hashimoto, G. L., Abe, Y., & Sugita, S. (2005) · Viva origino