Cited by 833Neutrophil, Myeloperoxidase and Oxidative MechanismsImmunodeficiency and Autoimmune DisordersBlood disorders and treatments

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Cloning the gene for an inherited human disorder—chronic granulomatous disease—on the basis of its chromosomal location

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Royer-Pokora, Brigitte, Kunkel, Louis M., Monaco, Anthony P., Goff, Sabra C., Newburger, Peter E., Baehner, Robert L., Cole, F. Sessions, Curnutte, John T., Orkin, Stuart H.·1986·Nature

DOI 10.1038/322032a0

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Abstract

The gene that is abnormal in the X-linked form of the phagocytic disorder chronic granulomatous disease has been cloned without reference to a specific protein by relying on its chromosomal map position. The transcript of the gene is expressed in the phagocytic lineage of haematopoietic cells and is absent or structurally abnormal in four patients with the disorder. The nucleotide sequence of complementary DNA clones predicts a polypeptide of at least 468 amino acids with no homology to proteins described previously.

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Molecular Cloning: A Laboratory Manual
Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589
DNA sequencing with chain-terminating inhibitors
Sanger, F., Nicklen, S., & Coulson, A. R. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.12.5463 · Cited by 68,572
Detection of specific sequences among DNA fragments separated by gel electrophoresis
Southern, E. M. (1975) · Journal of Molecular Biology · doi:10.1016/s0022-2836(75)80083-0 · Cited by 32,245
Molecular Cloning. A Laboratory Manual
Wood, E. (1983) · Biochemical Education · doi:10.1016/0307-4412(83)90068-7 · Cited by 29,534
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
Feinberg, A. P., & Vogelstein, B. (1983) · Analytical Biochemistry · doi:10.1016/0003-2697(83)90418-9 · Cited by 24,512
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
Chirgwin, J. M., Przybyla, A., MacDonald, R. J., & Rutter, W. J. (1979) · Biochemistry · doi:10.1021/bi00591a005 · Cited by 21,460
[57] Sequencing end-labeled DNA with base-specific chemical cleavages
Maxam, A. M., & Gilbert, W. (1980) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(80)65059-9 · Cited by 13,943
Construction of a genetic linkage map in man using restriction fragment length polymorphisms.
Botstein, D., White, R. L., Skolnick, M. H., & Davis, R. W. (1980) · Europe PMC (PubMed Central) · Cited by 8,327
Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter
Melton, D. A., Krieg, P. A., Rebagliati, M. R., Maniatis, T., Zinn, K., & Green, M. R. (1984) · Nucleic Acids Research · doi:10.1093/nar/12.18.7035 · Cited by 6,324
[2] New M13 vectors for cloning
Messing, J. W. (1983) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(83)01005-8 · Cited by 5,240

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Botstein, D., White, R. L., Skolnick, M. & Davis, R. W. Am. J. hum. Genet. 32, 314–331 (1980).
Francke, U. et al. Am. J. hum. Genet. 37, 250–267 (1985).

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Lau, Y. (1988) · Enlighten: Theses (The University of Glasgow)
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Сергеевич, Е. Е. (2020) · Научное обозрение Медицинские науки (Scientific Review Medical Sciences) · doi:10.17513/srms.1090
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Valente, E. M. (2003) · UCL Discovery (University College London)
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Casimir, C. M. (1999) · Blood cell biochemistry · doi:10.1007/978-1-4615-4889-8_6
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Cole, T. R. P. (2022) · doi:10.1093/med/9780198870197.003.0009
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Tsui, L., & Steve, W. S. (2001) · Biotechnology · doi:10.1002/9783527620876.ch2
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Metzler, D. E., Metzler, C. M., & Sauke, D. J. (2001) · Elsevier eBooks · doi:10.1016/b978-012492543-4/50029-5
Biochemie und Molekularbiologie 1986
(1987) · Nachrichten aus Chemie Technik und Laboratorium · doi:10.1002/nadc.19870350207
Review
(1991) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.1991.29.1.13
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Kruskal, B. A., & Ezekowitz, R. A. B. (1994) · Springer eBooks · doi:10.1007/978-94-011-0233-9_11
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Devor, E. J. (1993) · Cambridge University Press eBooks · doi:10.1017/chol9780521332866.013
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Übersichtsreferate
(1987) · Journal of Laboratory Medicine · doi:10.1515/labm.1987.11.7-8.280
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Lionakis, M. S. (2020) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.733574909.793572026
Blut
Petrides, P. E. (1988) · Springer-Lehrbuch · doi:10.1007/978-3-642-87858-9_30
Mapping the Human Genome
(1987) · The Lancet · doi:10.1016/s0140-6736(87)91676-x
Genomics and Pediatric Research
Boright, A. P. (2002) · Pediatric Research · doi:10.1203/01.pdr.0000042461.81761.0b
Blut
Petrides, P. E. (1988) · Springer-Lehrbuch · doi:10.1007/978-3-662-09348-1_30

Authors: Royer-Pokora, B., Kunkel, L. M., Monaco, A. P., Goff, S. C., Newburger, P. E., Baehner, R. L., Cole, F. S., Curnutte, J. T., & Orkin, S. H.
Affiliations: Harvard University (US)
University of Massachusetts Chan Medical School (US)
University of Michigan (US)
Boston Children's Hospital (US)
ORCID: Kunkel, Louis M.
Monaco, Anthony P.
Newburger, Peter E.
Orkin, Stuart H.
Venue: Nature
Publisher: Springer Science and Business Media LLC
Published: 1986-07
Volume: 322
Issue: 6074
Pages: 32-38
ISSN: 0028-0836 (ISSN-L)
1476-4687
DOI: 10.1038/322032a0
OpenAlex: W2040096357
Cited by: 833
References: 43
Citations by year: 2026: 7 · 2025: 5 · 2024: 2 · 2023: 13 · 2022: 5 · 2021: 17 · 2020: 8 · 2019: 13 · 2018: 10 · 2017: 11 · 2016: 18 · 2015: 12 · 2014: 16 · 2013: 19 · 2012: 14
FWCI: 26.84
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.springer.com/tdm (tdm)
Locations: Nature (publishedVersion)
PubMed (publishedVersion)
Deep Blue (University of Michigan) (submittedVersion)
Funders: National Cancer Institute (CA 38325)
National Institute of Allergy and Infectious Diseases (AI-21320)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD18661)
Topics: Life Sciences › Immunology and Microbiology › Immunology › Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Life Sciences › Immunology and Microbiology › Immunology › Immunodeficiency and Autoimmune Disorders
Health Sciences › Medicine › Hematology › Blood disorders and treatments
Keywords: chronic granulomatous disease, gene cloning, X-linked inheritance, chromosome mapping, phagocytes, gene expression, nucleotide sequence
MeSH terms: Amino Acid Sequence, Base Sequence, Chromosome Deletion, Chromosome Mapping, Cloning, Molecular, DNA, Gene Expression Regulation, Granulomatous Disease, Chronic, Humans, RNA, Tissue Distribution, Transcription, Genetic, Leukemia, Myeloid, Acute

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Cloning the gene for an inherited human disorder—chronic granulomatous disease—on the basis of its chromosomal location

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