A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

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Items 901–1,000 of 1,001

  1. Frequent allelic deletion at a novel locus on chromosome 5 in human lung cancer
    Ilse Wieland, Malte Böhm · 1994 · Lung Cancer
  2. Linkage analysis of families with hereditary retinoblastoma: nonpenetrance of mutation, revealed by combined use of markers within and flanking the RB1 gene.
    Hans Scheffer, G.J. te Meerman, Yvonne C. M. Kruize, A H van den Berg, Dirk Penninga, Karel E.W.P. Tan, D. J. Derkinderen, Charles H. C. M. Buys · 1989 · Europe PMC (PubMed Central)
  3. Characterization of deletions at the retinoblastoma locus in patients with bilateral retinoblastoma
    Kai Kloss, Petra Währisch, Valerie Greger, Elmar P. Messmer, Henning Fritze, W Höpping, Eberhard Passarge, Bernhard Horsthemke · 1991 · American Journal of Medical Genetics
  4. Genetic aspects of prostate cancer
    Alain Latil, Rosette Lidereau · 1998 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
  5. Structure and expression of the Xenopus retinoblastoma gene
    Olivier Destrée, Kelvin T. Lam, L.Joselin Peterson-Maduro, Karin Eizema, Lisa Diller, Magdalena A. Gryka, Thierry Frébourg, Ellen K. Shibuya, Stephen Henry Friend · 1992 · Developmental Biology
  6. Detection of submicroscopic deletions and a DNA polymorphism at the retinoblastoma locus
    Bernhard Horsthemke, Valerie Greger, H.J. Barnert, Wolfgang H�pping, Eberhard Passarge · 1987 · Human Genetics
  7. Osteosarcoma: prognosis plateau warrants retinoblastoma pathway targeted therapy
    Sarah E. Ballatori, Philip W. Hinds · 2016 · Signal Transduction and Targeted Therapy
  8. Computational and Artificial Intelligence Techniques for Drug Discovery and Administration
    K. Balasubramanian · 2021 · Elsevier eBooks
  9. What is Drosophila Telling Us About Cancer?
    Cécilia de Lorenzo, Bernard M. Mechler, Peter J. Bryant · 1999 · Cancer and Metastasis Reviews
  10. The retinoblastoma protein—from bench to bedside
    Sibylle Mittnacht · 2005 · European Journal of Cell Biology
  11. Newly established human retinoblastoma cell lines exhibit an “immortalized” but not an invasive phenotype in vitro
    Sahine Griegel, Hong Chen, Roland Frötschl, Dieter F. Hülser, Valerie Greger, Bemhard Horsthemke, Manfred F. Rajewsky · 1990 · International Journal of Cancer
  12. A Transgenic Mouse Model for Trilateral Retinoblastoma
    J M O'Brien · 1990 · Archives of Ophthalmology
  13. Common Variants in RB1 Gene and Risk of Invasive Ovarian Cancer
    Honglin Song, Susan J. Ramus, Danielle Shadforth, Lydia Quaye, Susanne K. Kjær, Richard A. DiCioccio, Alison M. Dunning, Estrid Vilma Solyom Høgdall, Claus Kim Høgdall, Alice S. Whittemore et al. · 2006 · Cancer Research
  14. Overproduction of Rb Protein after the G 1 /S Boundary Causes G 2 Arrest
    Vassiliki Karantza, Anjli P. Maroo, David S. Fay, John M. Sedivy · 1993 · Molecular and Cellular Biology
  15. RBP1 Family Proteins Exhibit SUMOylation-Dependent Transcriptional Repression and Induce Cell Growth Inhibition Reminiscent of Senescence
    Olivier Binda, Jean-Sébastien Roy, Philip E. Branton · 2006 · Molecular and Cellular Biology
  16. Analysis of chromosome 6 deletions in lymphoid malignancies provides evidence for a region of minimal deletion within a 2-megabase segment of 6q21
    T G Sherratt, Maria Cristina Morelli, John Michael Boyle, Christine J. Harrison · 1997 · Chromosome Research
  17. Positive and negative controls on cell growth
    Robert A. Weinberg · 1989 · Biochemistry
  18. Genome imprinting and carcinogenesis
    Carmen Sapienza · 1991 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  19. A History of Cancer Research: Tumor Suppressor Genes
    Joseph S. Lipsick · 2020 · Cold Spring Harbor Perspectives in Biology
  20. Polyamine metabolism during exponential growth transition in Scots pine embryogenic cell culture
    Jaana Vuosku, Marjaana Suorsa, Maria Ruottinen, Suvi Sutela, Riina Muilu–Mäkelä, R. Julkunen-Tiitto, Tytti Sarjala, Peter B. Neubauer, Hely Häggman · 2012 · Tree Physiology
  21. Next-generation gene targeting in the mouse for functional genomics
    Yoichi Gondo, Ryutaro Fukumura, Takuya Murata, Shigeru Makino · 2009 · BMB Reports
  22. Matrix and Backstage: Cellular Substrates for Viral Vaccines
    Ingo Jordan, Volker Sandig · 2014 · Viruses
  23. Loss of heterozygosity at 11q23.1 and survival in breast cancer: Results of a large European study
    Kirsten Laake, Virpi Launonen, Dieter Niederacher, Sigfridur Gudlaugsdottir, Susanne Seitz, Pascale G. Rio, Marie-H�l�ne Champ�me, Ivan Bièche, Daniel Birnbaum, Gavin R. M. White et al. · 1999 · Genes Chromosomes and Cancer
  24. Temperature-Sensitive RB Mutations Linked to Incomplete Penetrance of Familial Retinoblastoma in 12 Families
    Gregory A. Otterson, Sanjay Modi, Kari Nguyen, Amy B. Coxon, Frederic J. Kaye · 1999 · The American Journal of Human Genetics
  25. Photoreceptor cell tumors in transgenic mice.
    Kim A. Howes, Jacques Lasudry, Daniel Myron Albert, Jolene J. Windle · 1994 · PubMed
  26. Matrigel promotes retinoblastoma cell growth in vitro and in vivo
    Adriana Albini, Antonella Melchiori, Angela Garofalo, Douglas McClain Noonan, Fulvio Basolo, Giulia Taraboletti, Gerald J. Chader, Raffaella Giavazzi · 1992 · International Journal of Cancer
  27. Molecular deletion of 9p sequences in non‐small cell lung cancer and malignant mesothelioma
    Robyn E. Lukeis, E. Dietzsch, Matthew T. Gillespie, O. Margaret Garson · 1993 · Genes Chromosomes and Cancer
  28. Invited review Oncogenes, growth, and the cell cycle: an overview
    George P. Studzinski · 1989 · Cell Proliferation
  29. Doxorubicin-Loaded Extracellular Vesicles Enhance Tumor Cell Death in Retinoblastoma
    Wissam Farhat, Vincent Yeung, Francesca Kahale, Mohit Parekh, JOHN CORTINAS, Lin Chen, Amy E. Ross, Joseph B. Ciolino · 2022 · Bioengineering
  30. Brain Abnormalities on MR Imaging in Patients with Retinoblastoma
    Firazia Rodjan, Pim de Graaf, Annette C. Moll, Saskia Marijke Imhof, Jonathan I. M. L. Verbeke, Esther Sánchez, Jonas A. Castelijns · 2010 · American Journal of Neuroradiology
  31. Molecular Pathobiology of Uveal Melanoma
    Justis P. Ehlers, J. William Harbour · 2005 · International Ophthalmology Clinics
  32. Conserved RB functions in development and tumor suppression
    Gabriel M. Gordon, Wei Du · 2011 · Protein & Cell
  33. A Parent-of-Origin Effect Impacts the Phenotype in Low Penetrance Retinoblastoma Families Segregating the c.1981C>T/p.Arg661Trp Mutation of RB1
    Philippine Eloy, Catherine Dehainault, Meriem Sefta, Isabelle Aerts, François Doz, Nathalie Cassoux, Livia Lumbroso-Le Rouïc, Dominique Stoppa‐Lyonnet, François Radvanyi, Gaël A. Millot et al. · 2016 · PLoS Genetics
  34. Roles of pRB in the Regulation of Nucleosome and Chromatin Structures
    Chiharu Uchida · 2016 · BioMed Research International
  35. Genetic susceptibility to cancer: ICRP Publication 79
    Approved by the Commission in May 1997 · 1998 · Annals of the ICRP
  36. Genetic testing and tumor surveillance for children with cancer predisposition syndromes
    Aarati Rao, Jennifer Rothman, Kim E. Nichols · 2008 · Current Opinion in Pediatrics
  37. Recent advances in retinoblastoma genetic research
    Kim E. Nichols, SUSAN E. WALTHER, Elizabeth Chao, Carol L. Shields, Arupa A. Ganguly · 2009 · Current Opinion in Ophthalmology
  38. The survival gene MED4 explains low penetrance retinoblastoma in patients with large RB1 deletion
    Catherine Dehainault, Alexandra Garancher, Laurent Castéra, Nathalie Cassoux, Isabelle Aerts, François Doz, Laurence Desjardins, Livia Lumbroso-Le Rouïc, Rocio Montes De Oca, Geneviève Almouzni et al. · 2014 · Human Molecular Genetics
  39. Regulation of Growth and Differentiation in Dictyostelium
    Yasuo Maeda · 2005 · International review of cytology
  40. Transcription and cancer
    Phillip M. Cox, Colin R. Goding · 1991 · British Journal of Cancer
  41. Bone tumors other than osteosarcoma after retinoblastoma
    Kathleen J. Helton, Barry D. Fletcher, Larry E. Kun, Jesse J. Jenkins, Charles B. Pratt · 1993 · Cancer
  42. Analysis of the p16INK4 and TP53 tumor suppressor genes in bone sarcoma pediatric patients
    Ana Patiño‐García, Luis Sierrasesúmaga · 1997 · Cancer Genetics and Cytogenetics
  43. Interaction between NF-kappa B- and serum response factor-binding elements activates an interleukin-2 receptor alpha-chain enhancer specifically in T lymphocytes.
    Anna A. Kuang, Kristine D. Novak, Sang‐Mo Kang, Kevin W. Bruhn, Michael J. Lenardo · 1993 · Molecular and Cellular Biology
  44. Molecular Genetic and Immunohistochemical Analysis of the Tumor Suppressor Genes Rb and p53 in Palmar and Aggressive Fibromatosis
    Elkay Muller, Massimo Castagnaro, D W Yandel, Hubert J. Wolfe, Benjamin Aaron Alman · 1996 · Diagnostic Molecular Pathology
  45. For our eyes only
    Ed Harlow · 1992 · Nature
  46. Infrequent Involvement of P53 Mutations and Loss of Heterozygosity of 17p in the Tumorigenesis of Renal Cell Carcinoma
    Τοyoaki Uchida, Chieki Wada, Toshiya Shitara, Shinichi Egawa, S Mashimo, Ken Koshiba · 1993 · The Journal of Urology
  47. Strategies for inhibiting multistage carcinogenesis based on signal transduction pathways
    I. Bernard Weinstein · 1988 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
  48. Consistent loss of the D5S89 locus mapping telomeric to the interleukin gene cluster and centromeric to EGR-1 in patients with 5q- chromosome
    L Nagarajan, Jiří Zavadil, David F. Claxton, Xinyan Y. Lu, Jeff Fairman, Janet A. Warrington, J.J. Wasmuth, A. Craig Chinault, CE Sever, ML Slovak · 1994 · Blood
  49. Genetic similarity between cancers and comorbid Mendelian diseases identifies candidate driver genes
    Rachel Melamed, Kevin Emmett, Chioma J. Madubata, Andrey Rzhetsky, Raúl Rabadán · 2015 · Nature Communications
  50. Genotype-phenotype analysis of ABCR variants in macular degeneration probands and siblings.
    Paul S. Bernstein, Mark Leppert, Nanda Singh, Michael C. Dean, Richard Alan Lewis, James R. Lupski, Rando L. Allikmets, Johanna M. Seddon · 2002 · PubMed
  51. Global issues and opportunities for optimized retinoblastoma care
    Brenda L. Gallie, Junyang Zhao, Kirk Vandezande, Abigail White, Helen S. L. Chan · 2007 · Pediatric Blood & Cancer
  52. Parental age and seasonal variation in the births of children with sporadic retinoblastoma: a mutation-epidemiologic study
    Ei Matsunaga, Kensei Minoda, M.S. Sasaki · 1990 · Human Genetics
  53. The Human as an Experimental System in Molecular Genetics
    Ray L. White, C. Thomas Caskey · 1988 · Science
  54. Molecular Detection of Chromosomal Translocations That Disrupt the Putative Retinoblastoma Susceptibility Locus
    Michael J. Higgins, M F Hansen, Webster K. Cavenee, Marc Lalande · 1989 · Molecular and Cellular Biology
  55. Progress in Thyroid Cancer Genomics: A 40-Year Journey
    James A. Fagin, Yuri E. Nikiforov · 2023 · Thyroid
  56. Inhibition of the Jagged/Notch pathway inhibits retinoblastoma cell proliferation via suppressing the PI3K/Akt, Src, p38MAPK and Wnt/β‑catenin signaling pathways.
    W. Xiao, Xiao-Yun Chen, Ming-Guang He · 2014 · Molecular Medicine Reports
  57. A Rapid and Sensitive Next-Generation Sequencing Method to Detect RB1 Mutations Improves Care for Retinoblastoma Patients and Their Families
    Wenhui L. Li, Jonathan David Buckley, Pedro Alfonso Sanchez-Lara, Dennis T. Maglinte, Lucy Viduetsky, Tatiana V. Tatarinova, Jennifer G. Aparicio, Jonathan W. Kim, Margaret Au, Dejerianne G. Ostrow et al. · 2016 · Journal of Molecular Diagnostics
  58. Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression
    Loredana Zocchi, Aditi Mehta, Stephanie Wu, Jie Wu, Yijun Gu, Jingtian Wang, Susie Suh, Robert C. Spitale, Claudia A. Benavente · 2020 · Oncogenesis
  59. Identification of candidate tumour suppressor gene loci for Hodgkin and Reed‐Sternberg cells by characterisation of homozygous deletions in classical Hodgkin lymphoma cell lines
    Maciej Giefing, J. Arnemann, José Ignacio Martín-Subero, Inga Nieländer, Stefanie Bug, Sylvia Hartmann, Norbert Arnold, Enrico Tiacci, Matthias Frank, Martin‐Leo Hansmann et al. · 2008 · British Journal of Haematology
  60. Changes in Retinoblastoma Cell Adhesion Associated with Optic Nerve Invasion
    Nikia A. Laurie, Adithi Mohan, Justina D. McEvoy, Damon R. Reed, Jiakun Zhang, Brett A. Schweers, Itsuki Ajioka, Virginia A. Valentine, Dianna A. Johnson, David H. Ellison et al. · 2009 · Molecular and Cellular Biology
  61. Dystonia-parkinsonism syndrome (XDP) locus: flanking markers in Xq12-q21.1.
    Kenneth G. Kupke, Manuel B. Graeber, U. Müller · 1992 · Europe PMC (PubMed Central)
  62. Osteosarcomas in transgenic mice expressing an alpha-amylase-SV40 T-antigen hybrid gene.
    Barbara B. Knowles, James W. McCarrick, Niles Wayne Fox, Davor Solter, Ivan Damjanov · 1990 · Europe PMC (PubMed Central)
  63. Allelic loss on chromosomes 2q, 3p and 21q: possibly a poor prognostic factor in oral squamous cell carcinoma
    Nobuharu Yamamoto, Jun-etsu Mizoe, Hideyuki Numasawa, Hirohiko Tsujii, Takahiko Shibahara, Hiroyasu Noma · 2003 · Oral Oncology
  64. Characterization of FAM10A4, a Member of the ST13 Tumor Suppressor Gene Family That Maps to the 13q14.3 Region Associated with B-Cell Leukemia, Multiple Myeloma, and Prostate Cancer
    Khalid Sossey‐Alaoui, Eiko Kitamura, Karen L. Head, John Kenneth Cowell · 2002 · Genomics
  65. Molecular genetics of human malignant melanoma
    Anthony P. Albino, Jane W. Fountain · 1993 · Cancer treatment and research
  66. Lessons from our children
    Sarah S. Donaldson · 1993 · International Journal of Radiation Oncology*Biology*Physics
  67. Somatic mosaicism in a patient with bilateral retinoblastoma.
    Valerie Greger, Eberhard Passarge, Bernhard Horsthemke · 1990 · Europe PMC (PubMed Central)
  68. Loss of constitutional heterozygosity in chromosome 10 in human glioblastoma
    Kunihiko Watanabe, Masakatsu Nagai, Susumu Wakai, T. Arai, K. Kawashima · 1990 · Acta Neuropathologica
  69. The two-hit theory hits 50
    Jonathan Chernoff · 2021 · Molecular Biology of the Cell
  70. Chromosome instability and deregulated proliferation: an unavoidable duo
    Courtney H. Coschi, Frederick A. Dick · 2012 · Cellular and Molecular Life Sciences
  71. Whole-Genome Sequencing of Retinoblastoma Reveals the Diversity of Rearrangements Disrupting RB1 and Uncovers a Treatment-Related Mutational Signature
    Helen Ruth Davies, Kevin D. Broad, Zerrin Onadim, Elizabeth A. Price, Xueqing Zou, Ibrahim Sheriff, Esin Kotiloğlu Karaa, Irene B. Scheimberg, Maddy Ashwin Reddy, Mandeep S. Sagoo et al. · 2021 · Cancers
  72. Familial Hyperparathyroidism
    Jenny E. Blau, William F. Simonds · 2021 · Frontiers in Endocrinology
  73. Mutations in the arginine-rich protein gene, in lung, breast, and prostate cancers, and in squamous cell carcinoma of the head and neck.
    Ravi Shridhar, Viji Shridhar, S Rivard, Jill M. Siegfried, Haline Pietraszkiewicz, John F. Ensley, Robert J. Pauley, David J. Grignon, Wael Sakr, O. J. Miller et al. · 1996 · PubMed
  74. Venturing Beyond the Sentence Level: Narrative Skills in Children with Hearing Loss
    Christina Reuterskiöld, Tina Ibertsson, Birgitta S. Sahlén · 2010 · The Volta Review
  75. Prognostic implications ofRB1tumour suppressor gene alterations in the clinical outcome of human osteosarcoma: a meta-analysis
    Wenqi Ren, Gu G · 2015 · European Journal of Cancer Care
  76. The origin of human retinoblastoma
    Rod Bremner, Julien Sage · 2014 · Nature
  77. Tumor suppressor genes in breast cancer.
    Steffi Oesterreich, Suzanne A.W. Fuqua · 1999 · Endocrine Related Cancer
  78. Karnofsky Memorial Lecture. Hereditary cancer: theme and variations.
    A G Knudson · 1997 · Journal of Clinical Oncology
  79. Paternal selection favoring mutant alleles of the retinoblastoma susceptibility gene
    Francis L. Munier, M. Anne Spence, Graziano Pescia, Aubin Balmer, Claude Gailloud, Francine Thonney, Guy van Melle, Hans Peter Rutz · 1992 · Human Genetics
  80. Latent Viruses and Mutated Oncogenes: No Evidence for Pathogenicity
    PETER H. DUESBERG, Jody R. Schwarz · 1992 · Progress in nucleic acid research and molecular biology
  81. Frequent allele loss on 9p21–22 defines a smallest common region in the vicinity of the CDKN2 gene in sporadic breast cancer
    Han‐Xiang An, Dieter Niederacher, Frauke Picard, Claudia R.C. van Roeyen, Hans Bender, Matthias W. Beckmann · 1996 · Genes Chromosomes and Cancer
  82. Frequent monoallelic loss of D13S319 in multiple myeloma patients shown by interphase fluorescence in situ hybridization
    Hong Chang, Derek Bouman, Cornelius F. Boerkoel, A. Keith Stewart, Jeremy Andrew Squire · 1999 · Leukemia
  83. Frequent loss of heterozygosity at chromosome 3p14.2–3p21 in human pancreatic islet cell tumours
    Marina N. Nikiforova, Yuri E. Nikiforov, Paul W. Biddinger, Douglas R. Gnepp, Luis Grosembacher, BERNARDO LEO WAJCHENBERG, James A. Fagin, Robert M. Cohen · 1999 · Clinical Endocrinology
  84. Smad7 Abrogates Transforming Growth Factor-β1-mediated Growth Inhibition in COLO-357 Cells through Functional Inactivation of the Retinoblastoma Protein
    Nichole Boyer Arnold, Murray Korc · 2005 · Journal of Biological Chemistry
  85. DNA-binding activity of retinoblastoma protein is intrinsic to its carboxyl-terminal region.
    N P Wang, Phang‐Lang Chen, Shi Huang, Larry A. Donoso, Wen‐Hwa Lee, Lee Ey · 1990 · PubMed
  86. RNA Polymerase III Transcription: Its Control by Tumor Suppressors and Its Deregulation by Transforming Agents
    Timothy R. P. Brown, Pamela Scott, Torsten Stein, Andrew G. Winter, Robert J. White · 2001 · Gene Expression
  87. Oncogenes and Tumor Suppressor Genes
    Georg Klein · 1988 · Acta Oncologica
  88. Growth factors and oncogenes in pancreatic cancer
    Nicholas Robert Lemoine, Peter A. Hall · 1990 · Baillière s Clinical Gastroenterology
  89. A sex chromosomal restriction-fragment-length marker linked to melanoma-determining Tu loci in Xiphophorus.
    Manfred Schartl · 1988 · Genetics
  90. Role of a tumor-suppressor gene in the negative control of anchorage-independent growth of Syrian hamster cells.
    Minoru Koi, Cynthia A. Afshari, Lois A. Annab, J. Carl Barrett · 1989 · Proceedings of the National Academy of Sciences
  91. A 230kb cosmid walk in the Duchenne muscular dystrophy gene: detection of a conserved sequence and of a possible deletion prone region
    Roland Heilig, Catherine Lemaire‐Vieille, Jean‐Louis Mandel · 1987 · Nucleic Acids Research
  92. Cross-species genomic and epigenomic landscape of retinoblastoma
    Claudia A. Benavente, Justina D. McEvoy, David Finkelstein, Lei Wei, Guolian Kang, Yong‐Dong Wang, Geoffrey A. M. Neale, Susan T. Ragsdale, Virginia A. Valentine, Armita Bahrami et al. · 2013 · Oncotarget
  93. Screening of RB1 gene mutations in Chinese patients with retinoblastoma and preliminary exploration of genotype-phenotype correlations.
    Ming-yan He, Yu An, Yijin Gao, Xiaowen Qian, Gang Li, Jiang Qian · 2014 · Europe PMC (PubMed Central)
  94. Reduction of circular RNA expression associated with human retinoblastoma
    Jiao Lyu, Yu Wang, Qiupeng Zheng, Peiyan Hua, Xiuyu Zhu, Jia-Kai Li, Jing Li, Xunda Ji, Peiquan Zhao · 2019 · Experimental Eye Research
  95. Allele-specific replication associated with aneuploidy in blood cells of patients with hematologic malignancies
    Avital Korenstein-Ilan, Aliza Amiel, Shadan Lalezari, Michael Lishner, Lydia Avivi · 2002 · Cancer Genetics and Cytogenetics
  96. The Structure of the Vertebrate Lens
    Jer R. Kuszak, M. Joseph Costello · 2004 · Cambridge University Press eBooks
  97. pRB, p107 and p130 as transcriptional regulators: Role in cell growth and differentiation
    Xavier Mayol, Xavier Graña · 1997 · Springer eBooks
  98. Detailed characterization of a homozygously deleted region corresponding to a candidate tumor suppressor locus at distal 17p13.3 in human lung cancer
    Hiroyuki Konishi, Miyabi Sugiyama, Kotaro Mizuno, Hiroko Saito, Yasushi Yatabe, Toshitada Takahashi, Hirotaka Osada, Takashi Takahashi · 2003 · Oncogene
  99. The second ETV6 allele is not necessarily deleted in acute leukemias with aETV6/ABL fusion
    Jürgen Hannemann, Lyn E. Healy, Susan A. Ridge, Leanne M. Wiedemann · 1998 · Genes Chromosomes and Cancer
  100. Regulation of cell lineage specification by the retinoblastoma tumor suppressor
    Skapek, S X, Pan, Y-R, Lee, E Y-H P · 2006 · Oncogene