A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

Friend, Stephen H., Bernards, Rene, Rogelj, Snezna, Weinberg, Robert A., Rapaport, Joyce M., Albert, Daniel M., Dryja, Thaddeus P.·1986·Nature

Cited by (1,001)

Items 801–900 of 1,001

  1. Transforming growth factor-beta inhibits phosphorylation of the retinoblastoma susceptibility gene product in human monocytic leukemia cell line JOSK-I.
    Yusuke Furukawa, S Uenoyama, Masatsugu Ohta, Atsuko Tsunoda, James D. Griffin, Masaki Saito · 1992 · Journal of Biological Chemistry
  2. Human Retinoblastoma Gene: Long-Range Mapping and Analysis of Its Deletion in a Breast Cancer Cell Line
    Robert Bookstein, Eva Y.-H.P. Lee, Alessandra Peccei, Wen‐Hwa Lee · 1989 · Molecular and Cellular Biology
  3. Growth and spread of hepatocellular carcinoma: A review of 240 consecutive autopsy cases
    Kei Yuki, Setsuo Hirohashi, Michiie Sakamoto, Toshio Kanai, Yukío Shimosato · 1990 · Cancer
  4. Cancer genomics
    Barbara L. Weber · 2002 · Cancer Cell
  5. Epigenetic and Copy Number Variation Analysis in Retinoblastoma by MS-MLPA
    Gabriella Livide, Maria Carmela Epistolato, Mariangela Amenduni, Vittoria Disciglio, Annabella Marozza, Maria Antonietta Mencarelli, Paolo Toti, Stefano Lazzi, Theodora Hadjistilianou, Sonia De Francesco et al. · 2012 · Pathology & Oncology Research
  6. Genetic and Epigenetic Discoveries in Human Retinoblastoma
    Justina D. McEvoy, Michael A. Dyer · 2015 · Critical Reviews™ in Oncogenesis
  7. RB silencing compromises the DNA damage-induced G2/M checkpoint and causes deregulated expression of the ECT2 oncogene
    T Eguchi, Tohru Takaki, Hiraku Itadani, H Kotani · 2006 · Oncogene
  8. Association of Loss of Heterozygosity at the p53 Locus with Chemoresistance in Osteosarcomas
    Akiteru Goto, Hiroaki Kanda, Yuichi Ishikawa, Seiichi Matsumoto, Noriyoshi Kawaguchi, Rikuo Machinami, Yo Kato, Tomoyuki Kitagawa · 1998 · Japanese Journal of Cancer Research
  9. Cloning of Breakpoints of a Chromosome Translocation Identifies the AN2 Locus
    Manfred Gessler, Kalle O. J. Simola, G.A.P. Bruns · 1989 · Science
  10. Deletion of a splice donor site ablates expression of the following exon and produces an unphosphorylated RB protein unable to bind SV40 T antigen.
    Jin‐Yuh Shew, Phang‐Lang Chen, Robert Bookstein, E Y Lee, Wen‐Hwa Lee · 1990 · PubMed
  11. Retinoblastoma protein is essential for early meiotic events in Arabidopsis
    Zhong Chen, James D. Higgins, Jeanie Tan Li Hui, Jing Li, F. Chris H. Franklin, Frédéric Berger · 2011 · The EMBO Journal
  12. Retinoblastoma: Problems and Perspectives from India
    S. Sahu, S Banavali, Suresh K. Pai, C. N. Nair, Purna Arun Kurkure, Shorouq Motwani, Suresh Hariram Advani · 1998 · Pediatric Hematology and Oncology
  13. Interaction of retinoblastoma protein family members with large T-antigen of primate polyomaviruses
    M. K. White, Kamel Khalili · 2006 · Oncogene
  14. p107 in the public eye: an Rb understudy and more
    Stacey E. Wirt, Julien Sage · 2010 · Cell Division
  15. Epimutation and cancer: A new carcinogenic mechanism of Lynch syndrome
    Kouji Banno, Iori Kisu, Megumi Yanokura, Kosuke Tsuji, Kenta Masuda, Arisa Ueki, Yusuke Kobayashi, Wataru Yamagami, Hiroyuki Nomura, Eiichiro Tominaga et al. · 2012 · International Journal of Oncology
  16. Molecular Genetics of RB1 ——The Retinoblastoma Gene
    Yannek I. Leiderman, Szilárd Kiss, Shizuo Mukai · 2007 · Seminars in Ophthalmology
  17. Multistage carcinogenesis in Barrett's esophagus
    Carlo C. Maley · 2006 · Cancer Letters
  18. Mutational activation of the c-K-ras gene in human pancreatic carcinoma
    Darryl K. Shibata, Gabriel Capellá, Manuel Perucho · 1990 · Baillière s Clinical Gastroenterology
  19. DNA Methylation and cancer
    Charles Spruck, William M. Rideout, Peter A. Jones · 1993 · Birkhäuser Basel eBooks
  20. Expression of the RB gene under the control of MuLV-LTR suppresses tumorigenicity of WERI-Rb-27 retinoblastoma cells in immunodefective mice.
    János Sümegi, É. Uzvölgyi, George Klein · 1990 · PubMed
  21. PERSPECTIVES ON CLASSIC ARTICLES: Metastasis Suppressor Genes
    Patricia Schriver Steeg · 2004 · JNCI Journal of the National Cancer Institute
  22. Solitary mast cell tumor of the lung
    Hideo Kudo, Shojiroh Morinaga, Yukío Shimosato, Masayuki Noguchi, Yasuyuki Mizutani, Hisao Asamura, Tsuguo Naruke · 1988 · Cancer
  23. PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation
    E Suzuki, Issei Imoto, Atiphan Pimkhaokham, T Nakagawa, Nobuyuki Kamata, Ken‐ichi Kozaki, Teruo Amagasa, Johji Inazawa · 2007 · Oncogene
  24. Phacoemulsification of posterior polar cataracts--a surgical challenge
    M W Lee · 2003 · British Journal of Ophthalmology
  25. Cell cycle alterations and lung cancer.
    Bruno Vincenzi, Gaia Schiavon, Marianna Silletta, Daniele Santini, Giuseppe Perrone, Mariapia Di Marino, Silvia Angeletti, Alfonso Baldi, Giuseppe Tonini · 2006 · PubMed
  26. Homozygous deletion, rearrangement and hypermethylation implicate chromosome region 3p14.3‐3p21.3 in sporadic breast‐cancer development
    Dorothy L. Buchhagen, Luping Qiu, Polly R. Etkind · 1994 · International Journal of Cancer
  27. Targeted therapies in myeloid leukemia
    A M John, Nicholas Shaun B. Thomas, Ghulam Jeelani Mufti, Rose Ann Padua · 2004 · Seminars in Cancer Biology
  28. Expression of Somatostatin Receptor Subtype 1–5 Genes in Human Pancreatic Cancer
    William E. Fisher, Trisha Doran, Peter Muscarella, László G. Boros, Edwin Christopher Ellison, William J. Schirmer · 1998 · JNCI Journal of the National Cancer Institute
  29. Multiple Dispersed Spontaneous Mutations: a Novel Pathway of Mutation in a Malignant Human Cell Line
    Janet C Harwood, A Tachibana, Mark Meuth · 1991 · Molecular and Cellular Biology
  30. Evidence that the familial adenomatous polyposis gene is involved in a subset of colon cancers with a complementable defect in c-myc regulation.
    Michael D. Erisman, J K Scott, Susan M. Astrin · 1989 · Proceedings of the National Academy of Sciences
  31. Inflammation, a silent killer in cancer is not so silent!
    Bharat Bhushan Aggarwal · 2009 · Current Opinion in Pharmacology
  32. Merkel Cell Polyomavirus: Oncogenesis in a Stable Genome
    M Ahmed, Camille H. Cushman, James A. DeCaprio · 2021 · Viruses
  33. Subsequent malignancies and their effect on survival in patients with retinoblastoma
    Eric T. Shinohara, Todd A. DeWees, Stephanie Mabry Perkins · 2013 · Pediatric Blood & Cancer
  34. Cdh11 Acts as a Tumor Suppressor in a Murine Retinoblastoma Model by Facilitating Tumor Cell Death
    M. Marchong, Christine Yurkowski, Clement Ma, Clarellen Spencer, S. Pajovic, B. Gallie · 2010 · PLoS Genetics
  35. Promoter hypermethylation of p73 and p53 genes in cervical cancer patients among north Indian population
    Abhimanyu Kumar Jha, Mohsen Nikbakht, Veena Jain, Alka Sehgal, Neena Capalash, Jagdeep Kaur · 2012 · Molecular Biology Reports
  36. Disparities in Retinoblastoma Presentation, Treatment, and Outcomes in Developed and Less-Developed Countries
    Gobind Singh, Anthony B. Daniels · 2016 · Seminars in Ophthalmology
  37. Loss of heterozygosity on chromosomes 3, 9, 13, and 17, including the retinoblastoma locus, in uveal melanoma.
    Andrea G. M. Scholes, Triantafillos Liloglou, Paul J. Maloney, Suzanne Hagan, Janice Nunn, Paul Stephenson Hiscott, Bertil E Damato, Ian Grierson, John K. Field · 2001 · PubMed
  38. Insights from mouse models into human retinoblastoma
    David P MacPherson · 2008 · Cell Division
  39. An increased relative frequency of retinoblastoma at a rural regional referral hospital in Miraj, Maharashtra, India
    Kirk R. Schultz, Shashi Ranade, Joseph Philip Neglia, Yaddanapudi Ravindranath · 1993 · Cancer
  40. Inheritance of Sinclair swine cutaneous malignant melanoma.
    R. G. Tissot, Craig W. Beattie, Max S. Amoss · 1987 · PubMed
  41. Loss of allelic heterozygosity on distal chromosome 1p in Merkel cell carcinoma
    Paul R. Harnett, John Henry Kearsley, Nicholas K. Hayward, Nicholas C. Dracopoli, Richard F. Kefford · 1991 · Cancer Genetics and Cytogenetics
  42. Detection of a Novel Cell Cycle-regulated Kinase Activity That Associates with the Amino Terminus of the Retinoblastoma Protein in G2/M Phases
    Jacqueline M. Sterner, Yoshihiko Murata, Hyung Goo Kim, Sarah B. Kennett, Dennis J. Templeton, Jonathan M. Horowitz · 1995 · Journal of Biological Chemistry
  43. Smallest region of overlap in Wilms tumor deletions uniquely implicates an 11p13 zinc finger gene as the disease locus
    Carl C.T. Ton, Vicki Huff, Katherine M. Call, Susan Lerner Cohn, Louise C. Strong, David E. Housman, Grady F. Saunders · 1991 · Genomics
  44. Deletion of chromosome region 13q14 is transmissible and does not always predispose to retinoblastoma
    John Kenneth Cowell, Paul Rutland, John L. Hungerford, Marcelle Jay · 1988 · Human Genetics
  45. The Molecular Genetics of Lung Cancer
    David S. Shames, Mitsuo Sato, John Dorrance Minna · 2008 · Lung Cancer
  46. DREAM On: Cell Cycle Control in Development and Disease
    Hayley C Walston, Audra N. Iness, Larisa Litovchick · 2021 · Annual Review of Genetics
  47. Targeting mechanism of the retinoblastoma tumor suppressor by a prototypical viral oncoprotein
    Lucia Beatriz Chemes, Ignacio Enrique Sanchez, Clara Smal, Gonzalo de Prat Gay · 2010 · FEBS Journal
  48. Interphase Cytogenetic Analysis of Solid Tumors by Non-Isotopic DNA in situ Hybridization
    Janneke C. Alers, Herman van Dekken · 1996 · Progress in Histochemistry and Cytochemistry
  49. Mothers’ perceptions of children's quality of life following early diagnosis and treatment for retinoblastoma (Rb)
    Linda Sheppard, Christine Eiser, Judith E. Kingston · 2005 · Child Care Health and Development
  50. Detection of small RB1 gene deletions in retinoblastoma by multiplex PCR and high-resolution gel electrophoresis
    Dietmar Rudolf Lohmann, Bernhard Horsthemke, Gabriele Gillessen‐Kaesbach, Fritz H. Stefani, Heinz H�fler · 1992 · Human Genetics
  51. MOLECULAR GENETICS AND BIOCHEMICAL MECHANISMS IN BLADDER CANCER
    David Sidransky, Edward M. Messing · 1992 · Urologic Clinics of North America
  52. Construction of a detailed molecular map of the mouse X chromosome by microcloning and interspecific crosses.
    Neil Brockdorff, Elizabeth Fisher, Julian Cavanna, Mary Frances Lyon, Steve D. M. Brown · 1987 · The EMBO Journal
  53. Rate-limiting steps: The genetics of pediatric cancers
    Daniel A. Haber, David E. Housman · 1991 · Cell
  54. Imaging of head and neck neoplasms in children
    Caroline D. Robson · 2010 · Pediatric Radiology
  55. Quercetin inhibits angiogenesis-mediated human retinoblastoma growth by targeting vascular endothelial growth factor receptor
    Wei Song, Xiaofei Zhao, Jiarui Xu, Han Zhang · 2017 · Oncology Letters
  56. Genetically Engineered Pigs to Study Cancer
    Daniela Kalla, Alexander Kind, Angelika Schnieke · 2020 · International Journal of Molecular Sciences
  57. Rhabdomyosarcoma-associated locus and MYOD1 are syntenic but separate loci on the short arm of human chromosome 11.
    Heidi J. Scrable, D K Johnson, Eugene M. Rinchik, Webster K. Cavenee · 1990 · Proceedings of the National Academy of Sciences
  58. Adenovirus E1A is associated with a serine/threonine protein kinase
    Christine H. Herrmann, L K Su, Ed Harlow · 1991 · Journal of Virology
  59. Familial cancer syndromes and clusters
    Frederick P. Li · 1990 · Current Problems in Cancer
  60. Hyperphosphorylation of the Retinoblastoma Gene Product Is Determined by Domains Outside the Simian Virus 40 Large-T-Antigen-Binding Regions
    Paul A. Hamel, Brenda L. Cohen, Lilly M. Sorce, Brenda L. Gallie, Robert A. Phillips · 1990 · Molecular and Cellular Biology
  61. Physical mapping of the cystic fibrosis region by pulsed-field gel electrophoresis
    Mitchell L. Drumm, Cassandra L. Smith, Michael C. Dean, Jeffery L. Cole, Michael C. Iannuzzi, Francis S. Collins · 1988 · Genomics
  62. Retinoblastoma (rb) gene product expression in lymphomas. Correlation with Ki67 growth fraction
    Juan C. Martínez, Miguel Angel Piris, Margarita Sánchez‐Beato, Raquel Villuendas, Juan Luis Orradre, Patricia Algara, L Sánchez‐Verde, Pedro Martínez · 1993 · The Journal of Pathology
  63. Unraveling the Function of the Retinoblastoma Gene
    Eldad Zacksenhaus, Rod Bremner, Zhe Jiang, R. Montgomery Gill, Michelle M. Muncaster, Mary Sopta, Robert A. Phillips, Brenda L. Gallle · 1993 · Advances in cancer research
  64. Discovery of the PTEN Tumor Suppressor and Its Connection to the PI3K and AKT Oncogenes
    Ramon E. Parsons · 2020 · Cold Spring Harbor Perspectives in Medicine
  65. Recent progress in retinoblastoma: Pathogenesis, presentation, diagnosis and management
    Min Zhou, Jieling Tang, Jiayan Fan, Xuyang Wen, Jianfeng Shen, Renbing Jia, Peiwei Chai, Xianqun Fan · 2024 · Asia-Pacific Journal of Ophthalmology
  66. Biomarkers in osteosarcoma
    Colin Kong, Marc F. Hansen · 2008 · Expert Opinion on Medical Diagnostics
  67. A Small Molecule Disruptor of Rb/Raf-1 Interaction Inhibits Cell Proliferation, Angiogenesis, and Growth of Human Tumor Xenografts in Nude Mice
    Rebecca Kinkade, Piyali Dasgupta, Adam Carie, Daniele Pernazza, Melanie A. Carless, Smitha Pillai, Nicholas J. Lawrence, Saı̈d M. Sebti, Srikumar Chellappan · 2008 · Cancer Research
  68. Retinoblastoma: Update on Current Management
    Nathalie Cassoux, Livia Lumbroso-Le Rouïc, Christine Lévy‐Gabriel, Isabelle Aerts, François Doz, Laurence Desjardins · 2017 · Asia-Pacific Journal of Ophthalmology
  69. Retinoblastoma Tumor Suppressor Protein Roles in Epigenetic Regulation
    Frederick Guzman, Yasamin Fazeli, Meagan Khuu, Kelsey Salcido, Sarah Singh, Claudia A. Benavente · 2020 · Cancers
  70. The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis
    Dannenberg, Jan-Hermen, te Riele, Hein P. J. · 2006 · Results and Problems in Cell Differentiation
  71. Detection of oncogenic human papillomavirus in sporadic retinoblastoma
    Maristela Amaral Palazzi, José Andrés Yunes, Izilda Aparecida Cardinalli, G. P. Stangenhaus, Sílvia Regina Brandalise, S. A. Ferreira, João Simão Sobrinho, Luisa L. Villa · 2003 · Acta Ophthalmologica Scandinavica
  72. Abnormal constitutional karyotypes in patients with neuroblastoma: a report of four new cases and review of 47 others in the literature
    Daniel Satgé, Sam W. Moore, Charles A. Stiller, Felix K Niggli, Kathy Pritchard‐Jones, Nick P. Bown, Jean Bénard, Dominique Plantaz · 2003 · Cancer Genetics and Cytogenetics
  73. Two-hit model for sporadic congenital anomalies in mice with the disorganization mutation.
    Jeffrey L. Crosby, Don S. Varnum, Joseph H. Nadeau · 1993 · Europe PMC (PubMed Central)
  74. Proadipocyte cell lines: models of cellular proliferation and differentiation
    Miriam J. Smyth, Rodney L. Sparks, Walker Wharton · 1993 · Journal of Cell Science
  75. The Ocular Melanoma Story LIII Edward Jackson Memorial Lecture: Part II
    Daniel Myron Albert · 1997 · American Journal of Ophthalmology
  76. Coexpression of cdk2/cdc2 and retinoblastoma gene products in colorectal cancer
    Hirofumi Yamamoto, Takushi Monden, Kyoji Ikeda, Hikaru Izawa, Keiichi Fukuda, M Fukunaga, Naohiro Tomita, Takashi Shimano, Hitoshi Shiozaki, Morito Monden · 1995 · British Journal of Cancer
  77. Revisiting retinoblastoma protein phosphorylation during the mammalian cell cycle
    Stephen Cooper, James Alan Shayman · 2001 · Cellular and Molecular Life Sciences
  78. Insulin regulates leptin secretion from 3T3–L1 adipocytes by a PI 3 kinase independent mechanism
    Zeigerer, Anja, Rodeheffer, Matthew S., McGraw, Timothy E., Friedman, Jeffrey M. · 2008 · Experimental Cell Research
  79. Expanding Roles of the E2F-RB-p53 Pathway in Tumor Suppression
    Yaxuan Zhou, Rinka Nakajima, Mashiro Shirasawa, Mariana Fikriyanti, Lin Zhao, Ritsuko Iwanaga, Andrew P. Bradford, Kenta Kurayoshi, Keigo Araki, Kiyoshi Ohtani · 2023 · Biology
  80. p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb–Hdm2 interaction and apoptosis
    Rachel B. Delston, Katie A. Matatall, Yang Sun, Michael D. Onken, J. William Harbour · 2010 · Oncogene
  81. Myeloid Cell COX-2 deletion reduces mammary tumor growth through enhanced cytotoxic T-lymphocyte function
    Edward P. Chen, Nune Markosyan, Emma Connolly, John A. Lawson, Xuanwen Li, Gregory R. Grant, Tilo Großer, Garret A. FitzGerald, Emer M. Smyth · 2014 · Carcinogenesis
  82. Lessons from Retinoblastoma: Implications for Cancer, Development, Evolution, and Regenerative Medicine
    Michael A. Dyer · 2016 · Trends in Molecular Medicine
  83. Reduced expression of deleted colorectal carcinoma (DCC) protein in established colon cancers
    Takanori Goi, A Yamaguchi, Gizo Nakagawara, Takeshi Urano, Hiroshi Shiku, Kazuo Furukawa · 1998 · British Journal of Cancer
  84. Abnormal Chromosome Repair and Risk of Developing Cancer
    William W. Au · 1993 · Environmental Health Perspectives
  85. Genetics and cytogenetics of retinoblastoma
    John Kenneth Cowell, Annette Hogg · 1992 · Cancer Genetics and Cytogenetics
  86. Combined Hamartoma of the Retina and Retinal Pigment Epithelium in a Patient With Neurofibromatosis Type 2
    Arunan Sivalingam, James Jay Augsburger, George Perilongo, Robert Zimmerman, Gabor Barabas · 1991 · Journal of Pediatric Ophthalmology & Strabismus
  87. Microdeletion syndromes, balanced translocations, and gene mapping.
    Albert Schinzel · 1988 · Journal of Medical Genetics
  88. Mutations in the RB1 Gene and Their Effects on Transcription
    James M. Dunn, Robert A. Phillips, X. Zhu, A Becker, Brenda L. Gallie · 1989 · Molecular and Cellular Biology
  89. Tumor suppressor genes and their roles in breast cancer
    Laura A. Cox, Gang Chen, Eva Y. -H. P. Lee · 1994 · Breast Cancer Research and Treatment
  90. SV40 and cell cycle perturbations in malignant mesothelioma
    Joseph R. Testa, Antonio Giordano · 2001 · Seminars in Cancer Biology
  91. Super selective ophthalmic artery delivery of chemotherapy for intraocular retinoblastoma: 'chemosurgery'The first Stallard lecture
    D. H. Abramson · 2010 · British Journal of Ophthalmology
  92. The molecular biology of retinoblastoma
    Milam A. Brantley, J. William Harbour · 2001 · Ocular Immunology and Inflammation
  93. Update on pathology of retinoblastoma
    Lata Singh, Seema Kashyap · 2018 · International Journal of Ophthalmology
  94. The Biology of the Nuclear Envelope and Its Implications in Cancer Biology
    María Alvarado-Kristensson, Catalina Ana Rosselló · 2019 · International Journal of Molecular Sciences
  95. Downregulation and aberrant promoter methylation of p16INK4A: A possible novel heritable susceptibility marker to retinoblastoma
    Paola Indovina, Antonio Acquaviva, Giulia De Falco, Valeria Rizzo, Anna Onnis, Anna Luzzi, Francesca De Giorgi, Theodora Hadjistilianou, Paolo Toti, Valentina Tomei et al. · 2009 · Journal of Cellular Physiology
  96. Eye Cancer: Unique Insights into Oncogenesis The Cogan Lecture
    J. William Harbour · 2006 · Investigative Ophthalmology & Visual Science
  97. Attitudes of 47 mothers of pediatric oncology patients toward genetic testing for cancer predisposition.
    Andrea Farkas Patenaude, Laura A. Basili, Diane L. Fairclough, F P Li · 1996 · Journal of Clinical Oncology
  98. The Nevoid Basal Cell Carcinoma Syndrome: Genetics and Mechanism of Carcinogenesis
    Allen E. Bale · 1997 · Cancer Investigation
  99. Molecular analysis of the retinoblastoma gene in primary ovarian cancer cells
    Yie Liu, Mats Hbyman, Yisong Wang, Sture Falkmer, Christina Hising, László Székely, Stefan Einhorn · 1994 · International Journal of Cancer
  100. Frequent Microsatellite Instabilities and Analyses of the Related Genes in Familial Gastric Cancers
    Yoshimitsu Akiyama, Hiromi Nagasaki, Zenro Nihei, Takeo Iwama∥, Tadashi Nomizu, Joji Utsunomiya, Yasuhito Yuasa · 1996 · Japanese Journal of Cancer Research