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Phosphorylation-Dephosphorylation of Enzymes

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Okadaic acid: a new probe for the study of cellular regulation

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Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism

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The Protein Phosphatases Involved in Cellular Regulation. 1. Classification and Substrate Specificities

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An improved procedure for identifying and quantitating protein phosphatases in mammalian tissues

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Casein Kinases—Multipotential Protein Kinases

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Separation and Characterization of Two Phosphorylase Phosphatase Inhibitors from Rabbit Skeletal Muscle

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Glycogen Synthetase Activity in Skeletal Muscle

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The Protein Phosphatases Involved in Cellular Regulation. 6. Measurement of Type-1 and Type-2 Protein Phosphatases in Extracts of Mammalian Tissues; an Assessment of Their Physiological Roles

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The Role of Cyclic-AMP-Dependent Protein Kinase in the Regulation of Glycogen Metabolism in Mammalian Skeletal Muscle

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Glycogen Synthase from Rabbit Skeletal Muscle; Effect of Insulin on the State of phosphorylation of the Seven Phosphoserine Residues in vivo

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Czech, M. P., Klarlund, J. K., Yagaloff, K. A., Bradford, A. P., & Lewis, R. E. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)37908-0 · Cited by 197

The Purification and Properties of Rabbit Skeletal Muscle Glycogen Synthase

Nimmo, H. G., Proud, C. G., & Cohen, P. (1976) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1976.tb10761.x · Cited by 196

ATP x Mg-dependent protein phosphatase from rabbit skeletal muscle. II. Purification of the activating factor and its characterization as a bifunctional protein also displaying synthase kinase activity.

Vandenheede, J. R., Yang, S. D., Goris, J., & Merlevede, W. J. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)70200-2 · Cited by 194

The MgATP-Dependent Protein Phosphatase and Protein Phosphatase 1 Have Identical Substrate Specificities

STEWART, A. A., Hemmings, B. A., Cohen, P., Goris, J., & Merlevede, W. J. (2005) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1981.tb06217.x · Cited by 190

Reconstitution of a Mg‐ATP‐dependent protein phosphatase and its activation through a phosphorylation mechanism

Hemmings, B. A., Resink, T. J., & Cohen, P. (1982) · FEBS Letters · doi:10.1016/0014-5793(82)80760-6 · Cited by 185

Separation and Characterisation of Glycogen Synthase Kinase 3,Glycogen Synthase Kinase 4 and Glycogen Synthase Kinase 5 from Rabbit Skeletal Muscle

Cohen, P., Yellowlees, D. C., Aitken, A., Donella-Deana, A., Hemmings, B. A., & Parker, P. J. (1982) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1982.tb05902.x · Cited by 180

Phosphorylation of the Type‐II Regulatory Subunit of Cyclic‐AMP‐Dependent Protein Kinase by Glycogen Synthase Kinase 3 and Glycogen Synthase Kinase 5

Hemmings, B. A., Aitken, A., Cohen, P., RYMOND, M., & Hofmann, F. B. (1982) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1982.tb06896.x · Cited by 179

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Picton, C., Woodgett, J. R., Hemmings, B. A., & Cohen, P. (1982) · FEBS Letters · doi:10.1016/0014-5793(82)81332-x · Cited by 176

The AMP-activated protein kinase: a multisubstrate regulator of lipid metabolism

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UDP-glucose: glycogen α-4-glucosyltransferase I kinase activity of purified muscle protein kinase

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Complete Primary Structure of Protein Phosphatase Inhibitor‐1 from Rabbit Skeletal Muscle

Aitken, A., BILHAM, T., & Cohen, P. (1982) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1982.tb06771.x · Cited by 163

The catalytic subunits of protein phosphatase‐1 and protein phosphatase 2A are distinct gene products

Tung, H. Y. L., Resink, T. J., Hemmings, B. A., Shenolikar, S., & Cohen, P. (1984) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1984.tb07962.x · Cited by 160

Independent mechanisms account for the regulation by protein kinase C of the epidermal growth factor receptor affinity and tyrosine-protein kinase activity.

Davis, R. J. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)76563-6 · Cited by 160

Adenosine 3′:5′-cyclic monophosphate- and guanosine 3′:5′-cyclic monophosphate-dependent protein kinases: Possible homologous proteins

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Characterisation of a Reconstituted Mg‐ATP‐Dependent Protein Phosphatase

Resink, T. J., Hemmings, B. A., Tung, H. Y. L., & Cohen, P. (1983) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1983.tb07485.x · Cited by 154

Glycogen Synthase from Rabbit Skeletal Muscle

Parker, P. J., Embi, N., Caudwell, F. B., & Cohen, P. (1982) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1982.tb05904.x · Cited by 151

The Regulation of Glycogen Metabolism. Purification and Properties of Protein Phosphatase Inhibitor-2 from Rabbit Skeletal Muscle

Foulkes, J. G., & Cohen, P. (1980) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1980.tb04489.x · Cited by 150

The calmodulin‐dependent glycogen synthase kinase from rabbit skeletal muscle

Woodgett, J. R., Davison, M. T., & Cohen, P. (1983) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1983.tb07766.x · Cited by 146

The Proteink Phosphatases Involved in Cellur Regulation. 2. Glycogen Metabolism

INGERBRITSEN, T. S., Foulkes, J. G., & Cohen, P. (1983) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1983.tb07358.x · Cited by 145

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Payne, M. E., & Soderling, T. R. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)70605-x · Cited by 138

The Hormonal Control of Glycogen Metabolism

Foulkes, J. G., & Cohen, P. (1979) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1979.tb13109.x · Cited by 132

A multifunctional calmodulin‐dependent protein kinase

McGuinness, T. L., Lai, Y. Y., Greengard, P., Woodgett, J. R., & Cohen, P. (1983) · FEBS Letters · doi:10.1016/0014-5793(83)80846-1 · Cited by 131

Rabbit skeletal muscle glycogen synthase. I. Relationship between phosphorylation state and kinetic properties.

Roach, P. J., Takeda, Y., & Larner, J. (1976) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)33634-7 · Cited by 130

Regulation of protein phosphatase‐1G from rabbit/skeletal muscle

Hubbard, M. J., & COHEN, P. (1989) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1989.tb15263.x · Cited by 129

Purification of a Hepatic S6 Kinase from Cycloheximide-treated Rats

Price, D. J., Nemenoff, R. A., & Avruch, J. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)80075-8 · Cited by 128

Influence Of Epinephrine and Insulin on Uridine Diphosphate Glucose-α-Glucan Transferase and Phosphorylase in Muscle

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Picton, C., Aitken, A., BILHAM, T., & Cohen, P. (1982) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1982.tb05903.x · Cited by 123

Multiple phosphorylation of rabbit skeletal muscle glycogen synthase. Evidence for interactions among phosphorylation sites and the resolution of electrophoretically distinct forms of the subunit.

DePaoli-Roach, A. A., Ahmad, Z., Camici, M., Lawrence, J. C., & Roach, P. J. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)44513-3 · Cited by 119

S6 kinase in quiescent Swiss mouse 3T3 cells is activated by phosphorylation in response to serum treatment.

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Specificity of a protein phosphatase inhibitor from rabbit skeletal muscle

Cohen, P., Nimmo, G. A., & ANTONIW, J. F. (1977) · Biochemical Journal · doi:10.1042/bj1620435 · Cited by 114

Glycogen synthetase kinase 2 (GSK 2); The identification of a new protein kinase in skeletal muscle

Nimmo, H. G., & Cohen, P. (1974) · FEBS Letters · doi:10.1016/0014-5793(74)80450-3 · Cited by 112

Studies on UDPG-α-glucan Transglucosylase. V. Two Forms of the Enzyme in Dog Skeletal Muscle and Their Interconversion*

Rosell-Pérez, M., & Larner, J. (1964) · Biochemistry · doi:10.1021/bi00889a014 · Cited by 111

Glycogen Synthase Kinase-2 and Phosphorylase Kinase Are the Same Enzyme

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Poulter, L., Ang, S.-G., Gibson, B. W., Williams, D. H., Holmes, C. F. B., Caudwell, F. B., Pitcher, J. A., & COHEN, P. (1988) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1988.tb14222.x · Cited by 102

Characterization of a rabbit skeletal muscle protein kinase (PC0.7) able to phosphorylate glycogen synthase and phosvitin.

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Rabbit skeletal muscle phosphorylase kinase. Comparison of glycogen synthase and phosphorylase as substrates.

DePaoli-Roach, A. A., Roach, P. J., & Larner, J. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50717-1 · Cited by 93

The Insulin Receptor: Structure and Functio

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Tamura, S., KIKUCHI, H., Kikuchi, K., Hiraga, A., & Tsuiki, S. (1980) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1980.tb04435.x · Cited by 87

Regulation of glycogen synthetase. Specificity and stoichiometry of phosphorylation of the skeletal muscle enzyme by cyclic 3':5'-AMP-dependent protein kinase.

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Multiple phosphorylation of rabbit skeletal muscle glycogen synthase. Comparison of the actions of different protein kinases capable of catalyzing phosphorylation in vitro.

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Stimulation of protein phosphatase activity by insulin and growth factors in 3T3 cells.

Chan, C. P., McNall, S. J., Krebs, E. G., & Fischer, E. H. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.17.6257 · Cited by 82

A Reinvestigation of the Phosphorylation of Rabbit Skeletal‐Muscle Glycogen Synthase by Cyclic‐AMP‐Dependent Protein Kinase

Embi, N., Parker, P. J., & Cohen, P. (1981) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1981.tb05252.x · Cited by 82

Hormonal control of glycogen synthase in rat hemidiaphragms. Effects of insulin and epinephrine on the distribution of phosphate between two cyanogen bromide fragments.

Lawrence, J. C., Hiken, J., DePaoli-Roach, A. A., & Roach, P. J. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)44514-5 · Cited by 79

Purification and properties of cyclic AMP-independent glycogen synthase kinase 1 from rabbit skeletal muscle.

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Purification and Physicochemical Properties of ATP Citrate (pro‐3S) Lyase from Lactating Rat Mammary Gland and Studies of Its Reversible Phosphorylation

Guy, P. S., Cohen, P., & Hardie, D. G. (1981) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1981.tb05160.x · Cited by 73

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Antagonistic effects of insulin and beta-adrenergic agonists on the activity of protein phosphatase inhibitor-1 in skeletal muscle of the perfused rat hemicorpus.

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Phosphorylation of glycogen synthase by cyclic AMP-independent casein kinase-2 from rabbit skeletal muscle.

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Identification of phosphorylation sites in peptides using a gas-phase sequencer

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Insulin and Glycogen Synthase

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Phosphorylation of glycogen synthase and of the beta subunit of eukaryotic initiation factor two by a common protein kinase.

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