Atomic structure of the MAP kinase ERK2 at 2.3 A resolution

Zhang, Faming, Strand, Arne, Robbins, David, Cobb, Melanie H., Goldsmith, Elizabeth J.·1994·Nature

Cited by (602)

Items 401–500 of 602

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    Hanna Brzeska, Brian M. Martin, Edward D. Korn · 1996 · Journal of Biological Chemistry
  2. Principles of Kinase Regulation
    Boštjan Kobe, Bruce E. Kemp · 2010 · Elsevier eBooks
  3. Functional divergence caused by mutations in an energetic hotspot in ERK2
    Clinton A. Taylor, Kevin W. Cormier, Shannon E. Keenan, Svetlana A. Earnest, Steve Stippec, Chonlarat Wichaidit, Yu-Chi Angela Juang, Junmei Wang, Stanislav Y. Shvartsman, Elizabeth J. Goldsmith et al. · 2019 · Proceedings of the National Academy of Sciences
  4. Active ERK 2 is sufficient to mediate growth arrest and differentiation signaling
    Pui–Kei Wu, Seung‐Keun Hong, Seunghee Yoon, Jong‐In Park · 2015 · FEBS Journal
  5. Effect of mutating the regulatory phosphoserine and conserved threonine on the activity of the expressed catalytic domain of Acanthamoeba myosin I heavy chain kinase
    Joanna Szczepanowska, Umamaheswari Ramachandran, Christopher J. Herring, James M. Gruschus, Jun Qin, Edward D. Korn, Hanna Brzeska · 1998 · Proceedings of the National Academy of Sciences
  6. Purification of a 12,020-Dalton Protein That Enhances the Activation of Mitogen-activated Protein (MAP) Kinase by MAP Kinase Kinase
    Anisa Scott, Clare M.M. Haystead, Timothy Haystead · 1995 · Journal of Biological Chemistry
  7. Conformational Diversity of Catalytic Cores of Protein Kinases
    Janusz M. Sowadski, Linda F. Epstein, Leszek Łankiewicz, Rolf Karlsson · 1999 · Pharmacology & Therapeutics
  8. A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host
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  9. Structure of extracellular signal-regulated kinase 2 in complex with ATP and ADP
    Jun Zhang, Paul Shapiro, Edwin V. Pozharski · 2012 · Acta Crystallographica Section F Structural Biology and Crystallization Communications
  10. Escherichia coli Isocitrate Dehydrogenase Kinase/Phosphatase
    Katrin Rittinger, Didier Négre, Gilles Divita, Marie Scarabel, Christelle Bonod‐Bidaud, Roger Sidney Goody, Alain J. Cozzone, Jc Cortay · 1996 · European Journal of Biochemistry
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  13. A method to predict residues conferring functional differences between related proteins: Application to MAP kinase pathways
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  14. Calculating Transfer Entropy from Variance–Covariance Matrices Provides Insight into Allosteric Communication in ERK2
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  15. Conformation selection by ATP-competitive inhibitors and allosteric communication in ERK2
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  16. Mammalian Raf‐1 is activated by mutations that restore Raf signaling in Drosophila
    Richard E. Cutler, Deborah K. Morrison · 1997 · The EMBO Journal
  17. Gene-regulating protein kinases as important anti-inflammatory targets
    Shripad S. Bhagwat, Anthony M. Manning, Merl F. Hoekstra, Alan J. Lewis · 1999 · Drug Discovery Today
  18. Phosphorylation of the Grb2- and Phosphatidylinositol 3-Kinase p85–binding p36/38 by Syk in Lck-Negative T Cells
    Maria von Willebrand, Scott Williams, Pankaj Tailor, Tomas Mustelin · 1998 · Cellular Signalling
  19. Analysis of crystal structure of Arabidopsis MPK6 and generation of its mutants with higher activity
    Bo Wang, Xinghua Qin, Juan Wu, Hongying Deng, Yuan Li, Hailian Yang, Zhongzhou Chen, Guoqin Liu, Dongtao Ren · 2016 · Scientific Reports
  20. The Two Non-Visual Arrestins Engage ERK2 Differently
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  21. Evaluation of broad spectrum protein kinase inhibitors to probe the architecture of the malarial cyclin dependent protein kinase Pfmrk
    Cassandra L. Woodard, Susan M. Keenan, Lucia Gerena, William Jeffrey Welsh, Jeanne A. Geyer, Norman C. Waters · 2007 · Bioorganic & Medicinal Chemistry Letters
  22. Exposure of protein kinase motifs that trigger binding of Hsp90 and Cdc37
    Thomas L. Prince, Robert L. Matts · 2005 · Biochemical and Biophysical Research Communications
  23. Rat ERK2 E320K
    C.A. Taylor th, Kevin W. Cormier, Y.-C. Juang, Elizabeth J. Goldsmith, Melanie H. Cobb · 2019 · Worldwide Protein Data Bank
  24. Activation Loop Plasticity and Active Site Coupling in the MAP Kinase, ERK2
    Laurel M. Pegram, Demian Riccardi, Natalie G. Ahn · 2023 · Journal of Molecular Biology
  25. Crystallization of MAP kinases
    Shoei‐Sheng Lee, Ting Zhou, Elizabeth J. Goldsmith · 2006 · Methods
  26. Active Mutants of the TCR-Mediated p38α Alternative Activation Site Show Changes in the Phosphorylation Lip and DEF Site Formation
    Netanel Tzarum, Ron Diskin, David Engelberg, Oded Livnah · 2010 · Journal of Molecular Biology
  27. Protein kinase superfamily — comparisons of sequence data with three-dimensional structures
    Lei Wei, Stevan R. Hubbard, Randall F. Smith, Leland Ellis · 1994 · Current Opinion in Structural Biology
  28. Crystallization and preliminary crystallographic analysis of recombinant human p38 MAP kinase
    Susan Pav, Della M. White, Sheri Rogers, K.M. Crane, Charles L. Cywin, J. Hopkins, M L Brown, Christopher A. Pargellis, L. Tong, William Sean Davidson · 1997 · Protein Science
  29. Myosin Light Chain Kinase
    James T. Stull, Joanna K. Krueger, Kristine E. Kamm, Zhong-Hua Gao, Gang Zhi, Roanna C. Padre · 1996 · Elsevier eBooks
  30. In vivo activation of recombinant cAPK catalytic subunit active site mutants by coexpression of the wild‐type enzyme, evidence for intermolecular cotranslational phosphorylation
    Andreas Girod, Volker Kinzel, Dirk Bossemeyer · 1996 · FEBS Letters
  31. Mitogen-activated protein kinase 4 of Leishmania parasite as a therapeutic target
    Parameswaran Saravanan, Santhosh Venkatesan, C. Gopi Mohan, Sanjukta Patra, Vikash Kumar Dubey · 2010 · European Journal of Medicinal Chemistry
  32. Interaction of Kinase-Interaction-Motif Protein Tyrosine Phosphatases with the Mitogen-Activated Protein Kinase ERK2
    Dana M. Francis, Dorothy Koveal, Antoni Tortajada, Rebecca Page, Wolfgang Peti · 2014 · PLoS ONE
  33. Pfnek3 functions as an atypical MAPKK in Plasmodium falciparum
    Huiyu Low, Yu Min Lye, Tiow‐Suan Sim · 2007 · Biochemical and Biophysical Research Communications
  34. Subdomain X of the Kinase Domain of Lck Binds CD45 and Facilitates Dephosphorylation
    Jackie Felberg, Dennis C. Lefebvre, Mindy Lam, Yanni Wang, David H.W. Ng, Darlene Birkenhead, Jennifer L. Cross, Pauline Johnson · 2004 · Journal of Biological Chemistry
  35. Development of a miniaturized diffusive gradients in thin films (DGT) device
    Nadia Alexa, Hao Zhang, Jamie R. Lead · 2009 · Analytica Chimica Acta
  36. Chapter 29. The MAP Kinase Family: New “MAPs” for Signal Transduction Pathways and Novel Targets for Drug Discovery
    Bernd Stein, David Anderson · 1996 · Annual reports in medicinal chemistry
  37. Large Scale Screening Assay for the Phosphorylation of Mitogen-Activated Protein Kinase in Cells
    Renate de Wit, Johannes Boonstra, Arie J. Verkleij, Jan A. Post · 1998 · SLAS DISCOVERY
  38. Structure Prediction and Validation of the ERK8 Kinase Domain
    Angela Strambi, Mattia Mori, Matteo Rossi, David Colecchia, Fabrizio Manetti, Francesca Carlomagno, Maurizio Botta, Mario Chiariello · 2013 · PLoS ONE
  39. Asp263 missense variants perturb the active site of human phosphoglucomutase 1
    Kyle M. Stiers, Abigail C. Graham, Bailee Nicole Kain, Lesa J. Beamer · 2017 · FEBS Journal
  40. Synergistic anticancer effect by targeting CDK2 and EGFR–ERK signaling
    Jinhuan Wu, Yuping Chen, Rui Li, Yaping Guan, M H Chen, Hui Yin, Xiaoning Yang, Mingpeng Jin, Bingsong Huang, Xin Ding et al. · 2023 · The Journal of Cell Biology
  41. Structure and dynamics of inactive and active MARK4: conformational switching through the activation process
    Sajjad Ahrari, Navid Mogharrab, Leila Navapour · 2019 · Journal of Biomolecular Structure and Dynamics
  42. Monophosphothreonyl extracellular signal-regulated kinases 1 and 2 (ERK1/2) are formed endogenously in intact cardiac myocytes and are enzymically active
    Peter H. Sugden, Thomais Markou, Stephen J. Fuller, El Li Tham, Jeffery D. Molkentin, Hugh F. Paterson, Angela Clerk · 2010 · Cellular Signalling
  43. Variants of the yeast MAPK Mpk1 are fully functional independently of activation loop phosphorylation
    Tal Goshen‐Lago, Anat Goldberg-Carp, Dganit Melamed Kadosh, Ilona Darlyuk‐Saadon, Chen Guang Bai, Natalie G. Ahn, Arie Admon, David Engelberg · 2016 · Molecular Biology of the Cell
  44. c-Jun N-terminal kinases 3 (JNK3) from orange-spotted grouper, Epinephelus coioides, inhibiting the replication of Singapore grouper iridovirus (SGIV) and SGIV-induced apoptosis
    Minglan Guo, Jingguang Wei, Yongcan Zhou, Qiwei Qin · 2016 · Developmental & Comparative Immunology
  45. Structural Consequences of Multisite Phosphorylation in the BAK1 Kinase Domain
    Alexander S. Moffett, Diwakar Shukla · 2020 · Biophysical Journal
  46. Isolation and characterization of an oilseed rape MAP kinase BnMPK3 involved in diverse environmental stresses
    Shunwu Yu, Lida Zhang, Kaijing Zuo, Dongqin Tang, Kexuan Tang · 2005 · Plant Science
  47. Identification of Csk tyrosine phosphorylation sites and a tyrosine residue important for kinase domain structure
    Vladimir Joukov, Mauno Vihinen, Satu Vainikka, Janusz M. Sowadski, Kari K. Alitalo, Mathias Bergman · 1997 · Biochemical Journal
  48. A novel mutation in the BMPR2 gene in familial pulmonary arterial hypertension
    Lijun Fu, Ai-qing Zhou, Meirong Huang, Shuhong Shen, Jie Shen, Zhi-fang ZHANG, Fen Li · 2008 · Chinese Medical Journal
  49. Functional analysis of domains in the Byr2 kinase
    Patricia Bauman, Charles F. Albright · 1998 · Biochimie
  50. Substrate recognition by casein kinase‐II: The role of histidine‐160
    Grażyna Dobrowolska, Flavio Meggio, Oriano Marin, Fred J. Lozeman, Dongxia Li, Lorenzo Alberto Pinna, Edwin G. Krebs · 1994 · FEBS Letters
  51. Identification, structure, and phylogenetic relationships of a mitogen-activated protein kinase homologue from the parasitic protist Entamoeba histolytica
    Doel Ray, Suman Dutta, Sampali Banerjee, Rahul Banerjee, Sanghamitra Raha · 2005 · Gene
  52. Digital Cloning: Identification of Human cDNAs Homologous to Novel Kinases through Expressed Sequence Tag Database Searching
    Hua‐Chien Chen, Hsing-Jien Kung, Dan R. Robinson · 1998 · Journal of Biomedical Science
  53. Integration of Hydrogen-Deuterium Exchange Mass Spectrometry with Molecular Dynamics Simulations and Ensemble Reweighting Enables High Resolution Protein-Ligand Modeling.
    Kyle C. Kihn, Olivia Purdy, Vincent M. Lowe, L. Slachtova, Ally K. Smith, Paul Shapiro, Daniel J. Deredge · 2024 · Journal of the American Society for Mass Spectrometry
  54. Using Caenorhabditis elegans as a model organism for evaluating extracellular signal-regulated kinase docking domain inhibitors
    Fengming Chen, Alexander D. MacKerell, Yuan Luo, Paul Shapiro · 2008 · Journal of Cell Communication and Signaling
  55. Interface Analysis of the Complex between ERK2 and PTP-SL
    Mihaela C. Balasu, Laurentiu N. Spiridon, Simona M. Miron, Constantin T. Craescu, Axel J. Scheidig, Andrei‐José Petrescu, Stefan Eugen Szedlacsek · 2009 · PLoS ONE
  56. Inhibition and activation of c-Src: the head and tail of a coin
    Yasuo Fukami, Tomomi Nagao, Tetsushi Iwasaki, Ken-Ichi Sato · 2002 · Pharmacology & Therapeutics
  57. Phosphorylation Effects on Flanking Charged Residues
    Alain Chavanieu, Noeleen E. Keane, Philip G. Quirk, Barry A. Levine, Bernard Calas, Lei Wei, Leland Ellis · 1994 · European Journal of Biochemistry
  58. 13 Cascade activation of the calmodulin kinase family
    Hisayuki Yokokura, Osamu Terada, Yasuhito Naito, Ryotaro Sugita, Hiroyoshi Hidaka · 1997 · Advances in second messenger and phosphoprotein research
  59. Glycogen Synthase Kinase 3 Gene Is Important in Growth and Molting of the Pacific White Shrimp Litopenaeus vannamei
    Ying Pang, Xiaojun Zhang, Jianbo Yuan, Xiaoxi Zhang, Manwen Su, Fuhua Li · 2021 · Frontiers in Marine Science
  60. Exploiting uncertainty measures in compounds activity prediction using support vector machines
    Sabina Podlewska, Wojciech Marian Czarnecki, Dawid Warszycki, Andrzej Jacek Bojarski · 2014 · Bioorganic & Medicinal Chemistry Letters
  61. Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d
    Deborah H. Brotherton, Venugopal Dhanaraj, Scott T. Wick, Leonardo Brizuela, Peter J. Domaille, Elena Volyanik, Xu Xu, Emilio Parisini, Brian O. Smith, Sharon J. Archer et al. · 1998 · Nature · Retracted
  62. Mutational Analysis of the Nucleotide Binding Site of the Epidermal Growth Factor Receptor and v-Src Protein-tyrosine Kinases
    Chung‐leung Chan, Gordon N. Gill · 1996 · Journal of Biological Chemistry
  63. Cell-cycle regulation and cell-type specification in the developing Drosophila compound eye
    Chonnettia Jones, Kevin Moses · 2004 · Seminars in Cell and Developmental Biology
  64. Detergent binding to unmyristylated protein kinase A—Structural implications for the role of Myristate
    Janusz M. Sowadski, Charles A. Ellis, Madhusudan · 1996 · Journal of Bioenergetics and Biomembranes
  65. Phosphoregulatory Tyrosine of Xenopus Mitogen‐Activated Protein Kinase is out of the Reach of the Enzyme Catalytic Center After Autophosphorylation
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  66. Structural basis for X-linked agammaglobulinemia (XLA): mutations at interacting Btk residues R562, W563, and A582
    Hina S. Maniar, Mauno Vihinen, A. D. B. WEBSTER, Lennart Nilsson, C.I.E. Smith · 1995 · Clinical Immunology and Immunopathology
  67. Pardaxin, an ionophore neurotoxin, induces PC12 cell death: activation of stress kinases and production of reactive oxygen species.
    Eugenia Bloch‐Shilderman, Hao Jiang, Philip Lazarovici · 2002 · PubMed
  68. Role of Intrinsically Disordered Regions in Acceleration of Protein–Protein Association
    Misiura, Mikita M., Kolomeisky, Anatoly B. · 2020 · The Journal of Physical Chemistry B
  69. Immunostimulatory efficacy and protective potential of putative TgERK7 protein in mice experimentally infected by Toxoplasma gondii
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  70. Assignment of Backbone Resonances in a Eukaryotic Protein Kinase – ERK2 as a Representative Example
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  71. A Dynamic Switch in Inactive p38γ Leads to an Excited State on the Pathway to an Active Kinase
    Phillip C. Aoto, Robyn L. Stanfield, Ian A. Wilson, H. Jane Dyson, Peter E. Wright · 2019 · Biochemistry
  72. Nuclear factor-erythroid 2-related factor 3 (NRF3) is low expressed in colorectal cancer and its down-regulation promotes colorectal cancer malignance through activating EGFR and p38/MAPK
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  73. Crystal Structure and Inhibitor Identifications Reveal Targeting Opportunity for the Atypical MAPK Kinase ERK3
    Martin Schröder, P. Filippakopoulos, Martin P. Schwalm, Carla Alamillo‐Ferrer, David H. Drewry, Stefan Knapp, A. Chaikuad · 2020 · International Journal of Molecular Sciences
  74. Conformation selection by ATP-competitive inhibitors and allosteric communication in ERK2
    Jake W. Anderson, David Vaisar, David N. M. Jones, Laurel M. Pegram, Guy P. A. Vigers, Huifen Chen, John G. Moffat, Natalie G. Ahn · 2023 · eLife
  75. 2 From phosphorylase to phosphorylase kinase
    Louise Napier Johnson, David Barford, David J. Owen, Martin E. M. Noble, Elspeth F. Garman · 1997 · Advances in second messenger and phosphoprotein research
  76. Epidermal growth factor receptor signaling cascade as target for tyrphostin (RG 50864) in epithelial cells
    Frédérique Nowak, Alain Jacquemin‐Sablon, Josiane Pierre · 1997 · Biochemical Pharmacology
  77. c-Jun N-terminal kinase (JNK) in Procambarus clarkii: Molecular characterization and involvement in oxidative stress-induced apoptosis during molting cycle
    Hongyan Tian, Wang Yuning, Wenping Yang, Fei Liu, Yebing Yu, Shengjie Ren, Aimin Wang, Dingdong Zhang · 2021 · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology
  78. Spotlight on the Ballet of Proteins: The Structural Dynamic Properties of Proteins Illuminated by Solution NMR
    Yuji Tokunaga, Thibault Viennet, Haribabu Arthanari, Koh Takeuchi · 2020 · International Journal of Molecular Sciences
  79. From Phosphorylase to Phosphorylase Kinase
    Louise Napier Johnson · 1997 · Springer eBooks
  80. Structural Studies of MAP Kinase Cascade Components
    Elizabeth J. Goldsmith, Xiaoshan Min, Haixia He, Tianjun Zhou · 2010 · Methods in molecular biology
  81. Structural Determinants of Substrate Selection by the Human Insulin‐Receptor Protein‐Tyrosine Kinase
    Noeleen E. Keane, Alain Chavanieu, Philip G. Quirk, James S. Evans, Barry A. Levine, Bernard Calas, Lei Wei, Leland Ellis · 1994 · European Journal of Biochemistry
  82. Role of Mitogen-Activated Protein Kinases and Protein Kinase C in Regulating Low-Density Lipoprotein Receptor Expression
    Kamal D. Mehta · 2002 · Gene Expression
  83. Phosphorylation-Sensitive Secondary Structure in a Synthetic Peptide Corresponding to the Activation Loop of MAP Kinase
    Alexander A. Tokmakov, Kenichi Sato, Yasuo Fukami · 1997 · Biochemical and Biophysical Research Communications
  84. Switching to Rac and Rho
    Christoph Block, Alfred Wittinghofer · 1995 · Structure
  85. Uncoupling p38α nuclear and cytoplasmic functions and identification of two p38α phosphorylation sites on β-catenin: implications for the Wnt signaling pathway in CRC models
    Martina Lepore Signorile, Candida Fasano, Giovanna Forte, Katia De Marco, Paola Sanese, Vittoria Disciglio, Elisabetta Di Nicola, Antonino Pantaleo, Cristiano Simone, Valentina Grossi · 2023 · Cell & Bioscience
  86. Apprehensions and emerging solutions in ML-based protein structure prediction
    Käthe M. Dahlström, Tiina Annamaria Salminen · 2024 · Current Opinion in Structural Biology
  87. Phosphorylation and ATP-binding induced conformational changes in the PrkC, Ser/Thr kinase from B. subtilis
    Paweł Gruszczyński, Michał Obuchowski, Rajmund Kaźmierkiewicz · 2010 · Journal of Computer-Aided Molecular Design
  88. Kinobead Profiling Reveals Reprogramming of BCR Signaling in Response to Therapy within Primary CLL Cells
    Adam J. Linley, Laura I. Karydis, Anil K. Mondru, Annalisa D’Avola, Humood Al Shmrany, Silvia Cicconi, Rebecca C. Griffin, Francesco Forconi, Andrew R. Pettitt, Nagesh Kalakonda et al. · 2021 · Clinical Cancer Research
  89. Peptide Inhibitors of the Mitogen-Activated Protein Kinase Pathway
    Yasuo Fukami, Alexander A. Tokmakov, Kumiko Konaka, Ken‐ichi Sato · 1999 · Pharmacology & Therapeutics
  90. Identification of a differentially expressed mRNA in axenic Leishmania panamensis amastigotes
    José Arturo Gutiérrez Triana, Fabìola Puentes, Alberto Moreno, Manuel Elkin Patarroyo, Luis Angel Murillo · 2001 · Memórias do Instituto Oswaldo Cruz
  91. Inhibition of MAPK Pathway by a Synthetic Peptide Corresponding to the Activation Segment of MAPK
    Alexander A. Tokmakov, Kenichi Sato, Kumiko Konaka, Yasuo Fukami · 1998 · Biochemical and Biophysical Research Communications
  92. An investigation of the role of Glu-842, Glu-844 and His-846 in the function of the cytoplasmic domain of the epidermal growth factor receptor
    John F. Timms, Martin E. M. Noble, Mary Gregoriou · 1995 · Biochemical Journal
  93. Isolation of temperature-sensitive mutations in the c-raf-1 catalytic domain and expression of conditionally active and dominant-defective forms of Raf-1 in cultured mammalian cells.
    Lu Kk, Alex Bazarov, Luke S. Yoon, John M. Sedivy · 1998 · PubMed
  94. Deregulation of mitogen-activated protein kinase at low pH due to a structural rearrangement of activation segment
    Alexander A. Tokmakov, Ken‐ichi Sato, Yasuo Fukami · 2000 · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
  95. Insulin receptor structural requirements for the formation of a ternary complex with IRS-1 and PI 3-kinase
    Peter A. Wilden, Ilsa I. Rovira, Dale E. Broadway · 1996 · Molecular and Cellular Endocrinology
  96. Kinetic Characterization of p34 /Cyclin B Kinase-Mediated Phosphorylation of Peptides Derived from Histone H1 Using Phosphocellulose Filter Binding and Scintillation Proximity Assays
    Jane E. Spencer-Fry, Gerard Brophy, Gerry O’Beirne, Neil D. Cook · 1997 · SLAS DISCOVERY
  97. Identification of a C-terminal Region That Is Required for the Nuclear Translocation of ERK2 by Passive Diffusion
    Sotaro Shibayama, Ryoko Shibata-Seita, Kenji Miura, Yutaka Kirino, Kunio Takishima · 2002 · Journal of Biological Chemistry
  98. Chapter 26. Protein Kinases and Phosphatases: Structural Biology and Synthetic Inhibitors
    Kenneth J. Murray, William J. Coates · 1994 · Annual reports in medicinal chemistry
  99. Design, synthesis and anti-cancer activity of novel 1,2,3-triazole hybrids of erlotinib against cervical cancer via MAPK signaling pathway
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