Mice lacking brain-derived neurotrophic factor develop with sensory deficits

Ernfors, Patrik, Lee, Kuo-Fen, Jaenisch, Rudolf·1994·Nature

DOI 10.1038/368147a0

Cited by (1,000)

Items 501–600 of 1,000

REVIEW ■ : Neurotrophic Factors and the Specification of Neural Function
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Olle Lindvall, Per Odin · 1994 · Current Opinion in Neurobiology
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Licznerski, Pawel, Jonas, Elizabeth A. · 2018 · Proceedings of the National Academy of Sciences
Effects of glossopharyngeal nerve section on the expression of neurotrophins and their receptors in lingual taste buds of adult mice
Cindy L. Yee, Dianna L Bartel, Thomas E. Finger · 2005 · The Journal of Comparative Neurology
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Richard Lee Clough, Richa Sud, Noa Davis-Silberman, Ronna P. Hertzano, Karen B. Avraham, Matthew C. Holley, Sally J. Dawson · 2004 · Biochemical and Biophysical Research Communications
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Hans Johnson, Tomas G. M. Hökfelt, Brun Ulfhake · 1996 · European Journal of Neuroscience
The effect of NGF, BDNF and bFGF on expression of galanin in cultured rat dorsal root ganglia
Nóra Kerekes, Marc Landry, Malin Ryd Rinder, Tomas G. M. Hökfelt · 1997 · Brain Research
Alterations in responsiveness to ethanol and neurotrophic substances in fetal septohippocampal neurons following chronic prenatal ethanol exposure
Marieta Barrow Heaton, Michael Paiva, Douglas J. Swanson, Don W. Walker · 1995 · Developmental Brain Research
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Kazuyoshi Tsutsui · 2006 · The Journal of Steroid Biochemistry and Molecular Biology
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Albert I. Chen, Keling Zang, Eliezer Masliah, Louis French Reichardt · 2016 · Scientific Reports
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Malcolm Robert Macleod, Timothy E. Allsopp, Joyce McLuckie, John S. Kelly · 2001 · Brain Research
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Gisela Grosse, Susann Djalali, Dong Rui Deng, Markus Höltje, Britta Hinz, Katharina Schwartzkopff, Marcel Cygon, Thomas Rothe, Thomas Stroh, Rainer Hellweg et al. · 2005 · Developmental Brain Research
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Genetic Knockdown of Brain-Derived Neurotrophic Factor in 3xTg-AD Mice Does Not Alter Aβ or Tau Pathology
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Teresa Valdés‐Sánchez, Martina Kirstein, Ana Pérez‐Villalba, José A. Vega, Isabel Fariñas · 2010 · Developmental Biology
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Increased synaptic inhibition in dentate gyrus of mice with reduced levels of endogenous brain-derived neurotrophic factor
Klara Olofsdotter, Olle Lindvall, Fredrik Asztély · 2000 · Neuroscience
Effects of neonatal exposure to anti-nerve growth factor on the number and size distribution of trigeminal neurones projecting to the molar dental pulp in rats
Xiaobing Qian, John Philip Naftel · 1996 · Archives of Oral Biology
Neonatally wounded skin induces NGF-independent sensory neurite outgrowth in vitro
Margaret L. Reynolds, Debie Alvares, Jacqueta Middleton, Maria Fitzgerald · 1997 · Developmental Brain Research
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Robert J. McEvilly, Michael G. Rosenfeld · 1999 · Progress in nucleic acid research and molecular biology
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B. Bernier, Isabelle Bar, Claude Pieau, Catherine Lambert de Rouvroit, André M. Goffinet · 1999 · The Journal of Comparative Neurology
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Timothy T Cho, Albert I. Farbman · 1999 · Molecular Brain Research
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