The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
ATM associates with and phosphorylates p53: mapping the region of interaction
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Cites
Kastan, M. B., Zhan, Q., El-Deiry, W. S., Carrier, F., Jacks, T., Walsh, W. V., Plunkett, B. S., Vogelstein, B., & Fornace, A. J. (1992) · Cell · doi:10.1016/0092-8674(92)90593-2 · Cited by 3,047 · cited 1×
“We and others have demonstrated that IR induction of p53 is dependent on the presence of ATM (Ref”
BackgroundA Single Ataxia Telangiectasia Gene with a Product Similar to PI-3 Kinase
Savitsky, K., Bar-Shira, A., Gilad, S., Rotman, G., Ziv, Y., Vanagaite, L., Tagle, D. A., Smith, S., Uziel, T., Sfez, S., et al. (1995) · Science · doi:10.1126/science.7792600 · Cited by 2,785
Self-citationDNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
Shieh, S.-Y., Ikeda, M., Taya, Y., & Prives, C. (1997) · Cell · doi:10.1016/s0092-8674(00)80416-x · Cited by 2,100
Self-citationDNA damage induces phosphorylation of the amino terminus of p53
Siliciano, J. D., Canman, C. E., Taya, Y., Sakaguchi, K., Appella, E., & Kastan, M. B. (1997) · Genes & Development · doi:10.1101/gad.11.24.3471 · Cited by 818
Self-citation
Research works printed but not linked: 16
- Lavin, M.F. & Shiloh, Y. The genetic defect in ataxia-telangiectasia. Annu. Rev. Immunol. 15, 177– 202 (1997). · DOI · Paper page
- Lavin, M.F. et al. Relationship of the ATM gene (mutated in ataxia-telangiectasia) to phosphalidylinositol 3-kinase. Trends Biochem. Sci. 20, 382–382 (1995). · DOI
- Khanna, K.K. et al. Interaction between ATM protein and c-Abl in response to DNA damage. Nature 387, 520– 523 (1997). · DOI · Paper page
- Morgan, S.E., Lovly, C., Pandita, T.K., Shiloh, Y. & Kastan, M.S. Fragments of ATM which have dominant-negative or complementing activity. Mol. Cell. Biol. 17, 2020– 2029 (1997). · DOI
- Baskaran, R. et al. Ataxia-telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation. Nature 387 , 516–519 (1997). · DOI · Paper page
- Khanna, K.K. & Lavin, M.F. Ionizing radiation and UV induction of p53 protein by different pathways in ataxia-telangiectasia cells. Oncogene 8, 3307–3312 ( 1993).
- Watters, D. et al. Cellular localization of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms. Oncogene 14, 1911–1921 ( 1997). · DOI
- Scott, S. et al. Cloning and expression of the ataxia-telangiectasia gene in baculovirus. Biochem. Biophys. Res. Commun. 245, 144–148 (1998). · doi:10.1006/bbrc.1998.8137
- Ruppert, J.M. & Stillman, B. Analysis of a protein-binding domain of p53. Mol. Cell. Biol. 13, 3811– 3820 (1993). · DOI
- Lees-Miller, S.P., Sakaguchi, K., Ullrich, S.J., Appella, E. & Anderson, C.W. Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53. Mol. Cell. Biol. 12, 5041– 5049 (1992). · DOI · Paper page
- Zhang, N. et al. Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype. Proc. Natl Acad. Sci. USA 94, 8021–8026 ( 1997). · DOI
- Zhang, N. et al. An anti-sense construct of full-length ATM cDNA imposes a radiosensitive phenotype on normal cells. Oncogene 17, 811–818 (1998). · DOI
- Liu, Z.G. et al. Three distinct signalling responses by murine fibroblasts to genotoxic stress. Nature 384, 273– 276 (1996). · DOI · Paper page
- Agarwal, M.L., Taylor, W.R., Chernov, M.V., Chernova, O.B. & Stark, G.R. The p53 network. J. Biol. Chem. 273, 1–4 ( 1998). · DOI · Paper page
- Waterman, M.J.F., Stavridi, E.S., Waterman, J.L.F. & Halazonetis, T.D. ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins. Nature Genet. 19, 175–178 (1998). · DOI · Paper page
- Frangioni, J.V. & Neel, B.G. Solubilization and purification of enzymatically active glutathione S transferase (pGEX) fusion proteins. Anal. Biochem. 216, 179 –187 (1993). · DOI · Paper page
Cited by
The DNA damage response: putting checkpoints in perspective
Zhou, B.-B. S., & Elledge, S. J. (2000) · Nature · doi:10.1038/35044005 · Cited by 3,213
ATM and related protein kinases: safeguarding genome integrity
Shiloh, Y. (2003) · Nature Reviews Cancer · doi:10.1038/nrc1011 · Cited by 2,577
Post-translational modification of p53 in tumorigenesis
Bode, A. M., & Dong, Z. (2004) · Nature Reviews Cancer · doi:10.1038/nrc1455 · Cited by 1,270
ATR-Mediated Checkpoint Pathways Regulate Phosphorylation and Activation of Human Chk1
Zhao, H., & Piwnica-Worms, H. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.13.4129-4139.2001 · Cited by 1,091
Regulation of p53 in response to DNA damage
Lakin, N. D., & Jackson, S. P. (1999) · Oncogene · doi:10.1038/sj.onc.1203015 · Cited by 987
Metadata
- Authors
- Khanna., K. K., Keating, K. E., Kozlov, S., Scott, S., Gatei, M., Hobson, K., Taya, Y., Gabrielli, B., Chan, D., Lees-Miller, S. P., & Lavin, M. F.
- Venue
- Nature Genetics
- Published
- 1998-12
- Volume
- 20
- Issue
- 4
- Pages
- 398-400
- ISSN
- 1061-4036 (ISSN-L)
- 1546-1718
- DOI
- 10.1038/3882
- OpenAlex
- W1994163195
- Cited by
- 486
- References
- 4
- FWCI
- 14.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
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- CoChat. (2026). Citation check: ATM associates with and phosphorylates p53: mapping the region of interaction. https://app.cochat.ai/papers/10.1038/3882
- The paper
- Khanna., K. K., Keating, K. E., Kozlov, S., Scott, S., Gatei, M., Hobson, K., Taya, Y., Gabrielli, B., Chan, D., Lees-Miller, S. P., & Lavin, M. F. (1998). ATM associates with and phosphorylates p53: mapping the region of interaction. Nature Genetics. https://doi.org/10.1038/3882
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
