Braking WAVEs
Integrity signals
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Claims the paper makes
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Each is checked against this paper’s own text: does it say what the citing paper says it does?
CYFIP1 is a member of the WAVE regulatory complex (WRC), representing a link between translational regulation and the actin cytoskeleton.
“It is a member of the WAVE regulatory complex (WRC), thus representing a link between translational regulation and the actin cytoskeleton.”
From New insights into the regulatory function of CYFIP1 in the context of WAVE- and FMRP-containing complexes (2017) · cites this paper as Cory and Ridley, 2002
The rest of the WRC complex resulting from the scission (e.g. WAVE and HSPC300) is actively involved in actin polymerization, together with Arp2/3.
“At the same time, the rest of the WRC complex resulting from the scission (e.g. WAVE and HSPC300) is actively involved in actin polymerization, together with Arp2/3 (Cory and Ridley, 2002).”
From New insights into the regulatory function of CYFIP1 in the context of WAVE- and FMRP-containing complexes (2017) · cites this paper as Cory and Ridley, 2002
Cited by
Sorted by citations
CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome
Abekhoukh, S., & Bardoni, B. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00081 · Cited by 110 · see citing works
Dendritic spine actin cytoskeleton in autism spectrum disorder
Joensuu, M., Lanoue, V., & Hotulainen, P. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.08.023 · Cited by 65 · see citing works
Abekhoukh, S., Sahin, H. B., Grossi, M., Zongaro, S., Maurin, T., Madrigal, I., Kazue-Sugioka, D., Raas-Rothschild, A., Doulazmi, M., Carrera, P., et al. (2017) · Disease Models & Mechanisms · doi:10.1242/dmm.025809 · Cited by 59 · see citing works
“This latter subcomplex interacts with Arp2/3, triggering actin polymerization (Cory and Ridley, 2002).”
Influential
- Authors
- Cory, G. O. C., & Ridley, A. J.
- Affiliations
- The Royal Free Hospital (GB)
- Corresponding author
- Ridley, Anne J.
- ORCID
- Ridley, Anne J.
- Venue
- Nature
- Published
- 2002-08-15
- Volume
- 418
- Issue
- 6899
- Pages
- 732-733
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2069870851
- Cited by
- 72
- References
- 0
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 1 · 2023: 3 · 2021: 1 · 2020: 3 · 2019: 2 · 2018: 3 · 2017: 4 · 2016: 1 · 2015: 4 · 2014: 5 · 2013: 4 · 2012: 3
- FWCI
- 1.10
- Type
- journal article
- Language
- en
- Update notices
- correction (2002-09-26)
- Open access
- closed
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (King's College London) (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Kinase Regulation and GTPase Signaling
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Microtubule and mitosis dynamics
- Keywords
- cell motility, cell shape, actin cytoskeleton, membrane protrusions, cell polarity, cell adhesion
- MeSH terms
- Actins, Animals, Carrier Proteins, Cell Movement, Humans, Microfilament Proteins, Protein Binding, Proteins, Signal Transduction, Oncogene Proteins, cdc42 GTP-Binding Protein, rac1 GTP-Binding Protein, Macromolecular Substances, Adaptor Proteins, Signal Transducing, Wiskott-Aldrich Syndrome Protein Family, Wiskott-Aldrich Syndrome Protein
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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