The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Running before we can walk?
Open accessAbstract
Two years ago, a new proteomic test was heralded as the future of cancer diagnostics. But since then, doubts about its effectiveness have begun to grow. Erika Check reports.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Use of proteomic patterns in serum to identify ovarian cancer
Petricoin, E. F., Ardekani, A. M., Hitt, B. A., Levine, P. J., Fusaro, V. A., Steinberg, S. M., Mills, G. B., Simone, C., Fishman, D. A., Kohn, E. C., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)07746-2 · Cited by 3,236
Cited by
Sharing Detailed Research Data Is Associated with Increased Citation Rate
Piwowar, H. A., Day, R. S., & Fridsma, D. B. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000308 · Cited by 881
Advances in Urinary Proteome Analysis and Biomarker Discovery
Fliser, D., Novak, J., Thongboonkerd, V., Argile[Combining Acute Accent]s, A. G. A., Jankowski, V., Girolami, M. A., Jankowski, J., & Mischak, H. (2007) · Journal of the American Society of Nephrology · doi:10.1681/asn.2006090956 · Cited by 286
Lessons from Controversy: Ovarian Cancer Screening and Serum Proteomics
Ransohoff, D. F. (2005) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/dji054 · Cited by 264
Tammen, H., Schulte, I., Hess, R., Menzel, C., Kellmann, M., Mohring, T., & Schulz‐Knappe, P. (2005) · PROTEOMICS · doi:10.1002/pmic.200401219 · Cited by 260
Overinterpretation of Clinical Applicability in Molecular Diagnostic Research
Lumbreras, B., Parker, L. A., Porta, M., Pollán, M., Ioannidis, J. P. A., & Hernández-Aguado, I. (2009) · Clinical Chemistry · doi:10.1373/clinchem.2008.121517 · Cited by 65
Metadata
- Authors
- Check, E.
- Venue
- Nature
- Published
- 2004-06-03
- Volume
- 429
- Issue
- 6991
- Pages
- 496-497
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W1978694357
- Cited by
- 168
- References
- 1
- FWCI
- 12.01
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Running before we can walk? https://app.cochat.ai/papers/10.1038/429496a
- The paper
- Check, E. (2004). Running before we can walk? Nature. https://doi.org/10.1038/429496a
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
