Virus treatment questioned after gene therapy death

Lehrman, Sally·1999·Nature

Cited by (577)

Items 101–200 of 577

  1. Cowpea mosaic virus nanoparticles for cancer imaging and therapy
    Perrin H. Beatty, John D. Lewis · 2019 · Advanced Drug Delivery Reviews
  2. Targeted Gene Delivery Mediated by Folate-polyethylenimine-block-poly(ethylene glycol) with Receptor Selectivity
    Han Lei Cheng, Jingling Zhu, Xuan Zeng, Jing Yue, Xian‐Zheng Zhang, Ren‐Xi Zhuo · 2009 · Bioconjugate Chemistry
  3. State-of-the-art human gene therapy: part I. Gene delivery technologies.
    Dan Wang, Guangping Gao · 2014 · PubMed
  4. Gene Therapy for Regenerative Medicine
    Hossein Hosseinkhani, Abraham Jacob Domb, Ghorbanali Sharifzadeh, Victoria Nahum · 2023 · Pharmaceutics
  5. Influence of acyl chain length on transfection mediated by acylated PEI nanoparticles
    Surendra Nimesh, Anita Aggarwal, Pradeep Kumar · 2006 · International Journal of Pharmaceutics
  6. Oncolytic Adenovirus: Strategies and Insights for Vector Design and Immuno-Oncolytic Applications
    Hanni K. Uusi-Kerttula, Sarah L. Hulin-Curtis, James Anthony Davies, Alan L. Parker · 2015 · Viruses
  7. Gene therapy for therapeutic angiogenesis in critically ischaemic lower limb – on the way to the clinic
    Tuomas T. Rissanen, Ismo Vajanto, Seppo Ylä‐Herttuala · 2001 · European Journal of Clinical Investigation
  8. Nonviral gene transfection nanoparticles: function and applications in the brain
    Indrajit Roy, Michal K. Stachowiak, Earl J. Bergey · 2008 · Nanomedicine Nanotechnology Biology and Medicine
  9. Gellan gum blended PEI nanocomposites as gene delivery agents: Evidences from in vitro and in vivo studies
    Ritu Goyal, Sushil K. Tripathi, Shilpa Tyagi, K. Ravi Ram, Kausar Mahmood Ansari, Y. Shukla, Debapratim Kar Chowdhuri, Pradeep Kumar, K.C. Gupta · 2011 · European Journal of Pharmaceutics and Biopharmaceutics
  10. Prospects for immunisation against Marburg and Ebola viruses
    Thomas W. Geisbert, Daniel G. Bausch, Heinz Feldmann · 2010 · Reviews in Medical Virology
  11. In vivonucleic acid delivery with PEI and its derivatives: current status and perspectives
    Wing‐Fu Lai · 2011 · Expert Review of Medical Devices
  12. Synthetic multi-layer nanoparticles for CRISPR-Cas9 genome editing
    Hao Tang, Xiaohui Zhao, Xingyu Jiang · 2020 · Advanced Drug Delivery Reviews
  13. Comparison of chitosan/siRNA and trimethylchitosan/siRNA complexes behaviour in vitro
    Vincent Dehousse, Nancy Garbacki, Séverine Jaspart, Delphine Castagne, Géraldine Piel, Alain Colige, Brigitte Évrard · 2010 · International Journal of Biological Macromolecules
  14. Design, preparation and application of nucleic acid delivery carriers
    Jun Yang, Hongmei Liu, Xin Zhang · 2013 · Biotechnology Advances
  15. Systemic dissemination of viral vectors during intratumoral injection.
    Yong Wang, Jiayi Hu, Ava Krol, Yong-Ping Li, Chuan‐Yuan Li, Fan Yuan · 2003 · PubMed
  16. Single-cell electroporation: current trends, applications and future prospects
    Srabani Kar, L. Mohan, Koyel Dey, Pallavi Shinde, Hwan‐You Chang, Moeto Nagai, Tuhin Subhra Santra · 2018 · Journal of Micromechanics and Microengineering
  17. Therapeutic promise of engineered nonsense suppressor tRNAs
    Joseph J. Porter, Christina S. Heil, John D. Lueck · 2021 · Wiley Interdisciplinary Reviews - RNA
  18. Transplantation of microencapsulated genetically modified xenogeneic cells augments angiogenesis and improves heart function
    Hong Zhang, S-J Zhu, W. Wang, Y Wei, S-S Hu · 2007 · Gene Therapy
  19. Carbonate apatite-facilitated intracellularly delivered siRNA for efficient knockdown of functional genes
    Sharif Hossain, Anthony Stanislaus, Ming Jang Chua, Seiichi Tada, Yoh‐ichi Tagawa, Ezharul Hoque Chowdhury, Toshihiro Akaike · 2010 · Journal of Controlled Release
  20. Antiangiogenic gene therapy with systemically administered sFlt-1 plasmid DNA in engineered gelatin-based nanovectors
    Sushma Kommareddy, Mansoor M. Amiji · 2007 · Cancer Gene Therapy
  21. Polymeric nanoparticles for gene delivery
    Jaspreet K. Vasir, Vinod D. Labhasetwar · 2006 · Expert Opinion on Drug Delivery
  22. Polymer‐mediated gene therapy: Recent advances and merging of delivery techniques
    Janelle Wes Salameh, Le Zhou, Sarah M. Ward, Cristiam F. Santa Chalarca, Todd S. Emrick, Marxa Leão Figueiredo · 2019 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
  23. On the Gene Delivery Efficacies of pH-Sensitive Cationic Lipids via Endosomal Protonation
    Rajkumar Sunil Singh, Christine Gonçalves, Pierre Sandrin, Chantal Pichon, Patrick Midoux, Arabinda Chaudhuri · 2004 · Chemistry & Biology
  24. Intratumoral injection of interleukin-12 plasmid DNA, either naked or in complex with cationic lipid, results in similar tumor regression in a murine model.
    Fushun Shi, Alexander L. Rakhmilevich, Chuck P Heise · 2002 · PubMed
  25. Gene Transfer: How Can the Biological Barriers Be Overcome?
    J. Escoffre, J. Teissié, M. Rols · 2010 · Journal of Membrane Biology
  26. Replicating Adenoviruses in Cancer Therapy
    Matthias Dobbelstein · 2004 · Current topics in microbiology and immunology
  27. Polyethylenimine-mediated gene delivery to the lung and therapeutic applications
    Massimo Conese · 2008 · Drug Design Development and Therapy
  28. Experimental and Clinical Studies
    Nondita Sarkar · 2005
  29. Linear polyethylenimine-graft-chitosan copolymers as efficient DNA/siRNA delivery vectors in vitro and in vivo
    Sushil K. Tripathi, Ritu Goyal, Pradeep Kumar · 2011 · Nanomedicine Nanotechnology Biology and Medicine
  30. Targeting the tumor microenvironment to enhance antitumor immune responses
    Kevin Van der Jeught, Lukasz Bialkowski, Lidia Daszkiewicz, Katrijn Broos, Cleo Goyvaerts, Dries Renmans, Sandra Van Lint, Carlo Heirman, Kris Thielemans, Karine Breckpot · 2014 · Oncotarget
  31. Cationic fluorine-containing amphiphilic graft copolymers as DNA carriers
    Shengdong Xiong, Ling Li, Jiang Jiang · 2010 · Biomaterials
  32. RNA Interference Technologies and Therapeutics
    Marta López‐Fraga, Tamara Martı́nez, Ana Jiménez · 2009 · BioDrugs
  33. Nitric oxide and oral cancer: A review
    Sheetal Korde, Gokul Sridharan, Amol Ramchandra Gadbail, V. Poornima · 2012 · Oral Oncology
  34. Electroporator with automatic change of electric field direction improves gene electrotransfer in-vitro
    Matej Reberšek, Cécile Faurie, Maša Kandušer · 2007 · BioMedical Engineering OnLine
  35. Polyethylenimine-based Formulations for Delivery of Oligonucleotides
    Fei Hao, Yuhuan Li, Jing Zhu, Jingyao Sun, Brian Marshall, Robert J. Lee, Lesheng Teng, Zhaogang Yang, Jing Xie · 2018 · Current Medicinal Chemistry
  36. Tissue engineering and regenerative medicine –where do we stand?
    Raymund E. Horch, Ulrich Kneser, Elias Polykandriotis · 2012 · Journal of Cellular and Molecular Medicine
  37. Application of Non-Viral Vectors in Drug Delivery and Gene Therapy
    Shuaikai Ren, Mengjie Wang, Chunxin Wang, Yan Wang, Changjiao Sun, Zhanghua Zeng, Haixin Cui, Xiang Zhao · 2021 · Polymers
  38. Development of pH–responsive nanocarriers using trimethylchitosans and methacrylic acid copolymer for siRNA delivery
    Vincent Dehousse, Nancy Garbacki, Alain Colige, Brigitte Évrard · 2009 · Biomaterials
  39. Ectopic bone formation by electroporatic transfer of bone morphogenetic protein-4 gene
    Koshi N. Kishimoto, Yuji Watanabe, Harukazu Nakamura · 2002 · Bone
  40. Bioresponsive polymers for nonviral gene delivery.
    Haijun Yu, Ernst Wagner · 2009 · PubMed
  41. Effects of branched or linear architecture of bioreducible poly(amido amine)s on their in vitro gene delivery properties
    Federico Martello, Martin Piest, Johan F. J. Engbersen, Paolo Ferruti · 2012 · Journal of Controlled Release
  42. Emerging Concepts and Challenges in Rheumatoid Arthritis Gene Therapy
    Andrei A. Deviatkin, Yulia A. Vakulenko, Lyudmila V. Akhmadishina, Vadim V. Tarasov, Marina I. Beloukhova, Andrey A. Zamyatnin, Alexander N. Lukashev · 2020 · Biomedicines
  43. Charge-conversional zwitterionic copolymer as pH-sensitive shielding system for effective tumor treatment
    Jie Chen, Xuan Dong, Tianshi Feng, Lin Lin, Zhaopei Guo, Jialiang Xia, Huayu Tian, Xuesi Chen · 2015 · Acta Biomaterialia
  44. Target delivery of a gene into the brain using the RVG29-oligoarginine peptide
    Gong Cheng, Xiangning Li, Lingling Xu, Yu-Hui Zhang · 2012 · Biomaterials
  45. LDLR-Gene therapy for familial hypercholesterolaemia: problems, progress, and perspectives
    Faisal Ahmad Al-Allaf, Charles Coutelle, Simon N. Waddington, Anna Louise David, Richard Paul Harbottle, Michael Themis · 2010 · International Archives of Medicine
  46. Polylysine-modified polyethylenimine inducing tumor apoptosis as an efficient gene carrier
    Huayu Tian, Lin Lin, Zixue Jiao, Zhaopei Guo, Jie Chen, Shiqian Gao, Xiaojuan Zhu, Xuesi Chen · 2013 · Journal of Controlled Release
  47. Scalable recovery of plasmid DNA based on aqueous two‐phase separation
    Andreas Frerix, Markus Müller, Maria‐Regina Kula · 2005 · Biotechnology and Applied Biochemistry
  48. A calcium phosphate‐based gene delivery system
    Huihua Fu, Yunhua Hu, Tim McNelis, Jeffrey O. Hollinger · 2005 · Journal of Biomedical Materials Research Part A
  49. Calcium phosphate/PLGA-mPEG hybrid porous nanospheres: A promising vector with ultrahigh gene loading and transfection efficiency
    Kewei Wang, Linzhu Zhou, Ying Sun · 2009 · Journal of Materials Chemistry
  50. Mucocutaneous leishmaniasis: an imported infection among travellers to central and South America
    Sukhbir Ahluwalia, Stephen D Lawn, Jeevendra Kanagalingam · 2004 · BMJ
  51. Biodegradable mPEG-b-P(MCC-g-OEI) copolymers for efficient gene delivery
    Xuan Dong, Huayu Tian, Lei Chen, Jie Chen, Xuesi Chen · 2011 · Journal of Controlled Release
  52. Nanobiomaterial vectors for improving gene editing and gene therapy
    Shao Wei Hu, Tao Ding, Honghai Tang, Huiping Guo, Wenguo Cui, Yilai Shu · 2023 · Materials Today
  53. Optimization of Electroporation-Enhanced Intradermal Delivery of DNA Vaccine Using a Minimally Invasive Surface Device
    Feng Wu Lin, Xuefei Shen, Gleb Kichaev et al. · 2012 · Human Gene Therapy Methods
  54. Synthesis and Characteristics of Biodegradable Pyridinium Amphiphiles Used for in vitro DNA Delivery
    Astrid Roosjen, J. Šmisterová, C. Driessen, Joachim T. Anders, Anno Wagenaar, Dick Hoekstra, Ron Hulst, Jan B. F. N. Engberts · 2002 · European Journal of Organic Chemistry
  55. Recombinant herpes vector-mediated analgesia in a primate model of hyperalgesia
    David C. Yeomans, Ying Chun Lu, Charles E. Laurito · 2005 · Molecular Therapy
  56. Nanopharmacology in translational hematology and oncology
    Ioana Berindan‐Neagoe, Cornelia Braicu, Lucian Craciun, Alexandra Iulia Irimie, Yoshiyuki Takahashi · 2014 · International Journal of Nanomedicine
  57. The roles of traditional Chinese medicine in gene therapy
    Changquan Ling, Lina Wang, Yuan Wang, Yuanhui Zhang, Zi-fei Yin, Meng Wang, Chen Ling · 2014 · Journal of Chinese Integrative Medicine
  58. Degradable Hybrid Materials Based on Cationic Acylhydrazone Dynamic Covalent Polymers Promote DNA Complexation through Multivalent Interactions
    Camille Bouillon, Delphine Paolantoni, Jennifer C. Rote, Yannick Bessin, Larryn W. Peterson, Pascal Dumy, Sébastien Ulrich · 2014 · Chemistry - A European Journal
  59. Recent progress in cationic polymeric gene carriers for cancer therapy
    Caina Xu, Huayu Tian, Xuesi Chen · 2017 · Science China Chemistry
  60. Nonviral gene therapy targeting cardiovascular system
    Cheng‐Huang Su, Yih‐Jer Wu, Hsueh-Hsiao Wang, Hung‐I Yeh · 2012 · American Journal of Physiology-Heart and Circulatory Physiology
  61. Enhancing Stem Cell-Based Therapeutic Potential by Combining Various Bioengineering Technologies
    In‐Sun Hong · 2022 · Frontiers in Cell and Developmental Biology
  62. Effective particle-mediated vaccination against mouse melanoma by coadministration of plasmid DNA encoding Gp100 and granulocyte-macrophage colony-stimulating factor.
    Alexander L. Rakhmilevich, Michael Imboden, Zhengling Hao · 2001 · PubMed
  63. Designing gene delivery vectors for cardiovascular gene therapy
    Andrew Howard Baker · 2003 · Progress in Biophysics and Molecular Biology
  64. DNA intercalation in neutral multilamellar membranes
    Tanja Pott, D. Roux · 2002 · FEBS Letters
  65. Emerging immune targets for the therapy of allergic asthma
    David Brian Corry · 2002 · Nature Reviews Drug Discovery
  66. Interleukin-2: evaluation of routes of administration and current delivery systems in cancer therapy.
    M. Shaker, H. Younes · 2009 · Journal of Pharmacy and Science
  67. Epigenetic Modulation of Collagen 1A1: Therapeutic Implications in Fibrosis and Endometriosis1
    Ye Zheng, Zaraq Khan, Valentina Zanfagnin, Luiz F. Correa, Abigail A. Delaney, Gaurang S. Daftary · 2016 · Biology of Reproduction
  68. Peptide-Based and Polypeptide-Based Gene Delivery Systems
    Jie Chen, Xiuwen Guan, Yingying Hu, Huayu Tian, Xuesi Chen · 2017 · Topics in Current Chemistry
  69. Surface decorations of poly(amidoamine) dendrimer by various pendant moieties for improved delivery of nucleic acid materials
    Ali Dehshahri, Hossein Sadeghpour · 2015 · Colloids and Surfaces B Biointerfaces
  70. Scaffold-mediated non-viral delivery platform for CRISPR/Cas9-based genome editing
    Jiah Shin Chin, Wai Hon Chooi, Hongxia Wang, William Ong, Kam W. Leong, Sing Yian Chew · 2019 · Acta Biomaterialia
  71. Gene delivery systems—gene therapy vectors for cystic fibrosis
    Daniel Tatting Klink, Dirk Schindelhauer, Andreas Laner, Torry A. Tucker, Zsuzsanna M. Bebok, Erik M. Schwiebert, Alan Boyd, Bob J. Scholte · 2004 · Journal of Cystic Fibrosis
  72. Up regulation of ICAM-1 gene expression inhibits tumour growth and liver metastasis in colorectal carcinoma
    Akiko Tachimori, Nobuya Yamada, Yoji Sakate · 2005 · European Journal of Cancer
  73. Multi‐armed poly( L ‐glutamic acid)‐graft‐oligoethylenimine copolymers as efficient nonviral gene delivery vectors
    Lei Chen, Huayu Tian, Jie Chen, Xuesi Chen, Yubin Huang, Xiabin Jing · 2009 · The Journal of Gene Medicine
  74. Systemic administration of a PEGylated adenovirus vector with a cancer-specific promoter is effective in a mouse model of metastasis
    Xingang Yao, Yasuo Yoshioka, Tomohiro Morishige · 2009 · Gene Therapy
  75. TALE nickase mediates high efficient targeted transgene integration at the human multi-copy ribosomal DNA locus
    Yong Chao Wu, Tieli Gao, Xiaolin Wang, Youjin Hu, Xuyun Hu, Zhiqing Hu, Jialun Pang, Zhuo Li, Jinfeng Xue, Mai Feng et al. · 2014 · Biochemical and Biophysical Research Communications
  76. Optimizing gene delivery vectors for the treatment of heart disease
    Steven James Gray, Richard Jude Samulski · 2008 · Expert Opinion on Biological Therapy
  77. In situ IGF-1 gene delivery to cells emerging from the injured anterior cruciate ligament
    Andre Friedrich Steinert, Meike Weber, Manuela Kunz, Glyn D. Palmer, Ulrich Aran Nöth, Christopher H. Evans, Martha Meaney Murray · 2007 · Biomaterials
  78. Novel polyethyleneimine-R8-heparin nanogel for high-efficiency gene delivery in vitro and in vivo
    Linjiang Song, Xiuqi Liang, Suleixin Yang, Ning Wang, Tao He, Yan Wang, Lan Zhang, Qinjie Wu, Changyang Gong · 2017 · Drug Delivery
  79. Gene therapy and genome editing for lipoprotein disorders
    Chen Gurevitz, Archna Bajaj, Amit V. Khera, Ron Do, Heribert Schunkert, Kiran Musunuru, Robert S. Rosenson · 2025 · European Heart Journal
  80. Nanomedicine–emerging or re-emerging ethical issues? A discussion of four ethical themes
    Christian Lenk, Nikola Biller‐Andorno · 2006 · Medicine Health Care and Philosophy
  81. Gene therapy for Fabry disease
    C. Sitaskas, Jeffrey A. Medin · 2001 · Journal of Inherited Metabolic Disease
  82. Awakening gene therapy with Sleeping Beauty transposons.
    Jeffrey J. Essner, R. McIvor, P. Hackett · 2005 · Current opinion in pharmacology (Print)
  83. Gene therapy: principles, challenges and use in clinical practice
    Cihan Ay, Andreas Reinisch · 2024 · Wiener klinische Wochenschrift
  84. Development of a Novel Systemic Gene Delivery System for Cancer Therapy with a Tumor-specific Cleavable PEG-lipid
    Hiroto Hatakeyama, Hidetaka Akita, Kentaro Kogure, Hideyoshi Harashima · 2007 · YAKUGAKU ZASSHI
  85. Improving Gene Delivery Efficiency of Bioreducible Poly(amidoamine)s via Grafting with Dendritic Poly(amidoamine)s
    Yanan Xue, Min Liu, Peng Lin, Shi‐Wen Huang, Ren‐Xi Zhuo · 2009 · Macromolecular Bioscience
  86. Pluronic-based cationic block copolymer for forming pDNA polyplexes with enhanced cellular uptake and improved transfection efficiency
    Tsz Chung Lai, Kazunori Kataoka, Glen S. Kwon · 2011 · Biomaterials
  87. Atomic-Scale Molecular Dynamics Simulations of DNA–Polycation Complexes: Two Distinct Binding Patterns
    Diana A. Kondinskaia, Andrei Yu. Kostritskii, Alexey M. Nesterenko · 2016 · The Journal of Physical Chemistry B
  88. Intracavernous Delivery of Synthetic Angiopoietin-1 Protein as a Novel Therapeutic Strategy for Erectile Dysfunction in the Type II Diabetic db/db Mouse
    Hai‐Rong Jin, Woo Jean Kim, Jae Sook Song, Shuguang Piao, Munkhbayar Tumurbaatar, Sun Hwa Shin, Min Ji Choi, Buyankhuu Tuvshintur, Kang‐Moon Song, Mi‐Hye Kwon et al. · 2010 · The Journal of Sexual Medicine
  89. Perylene diimide-based treatment and diagnosis of diseases
    Zhining Zhao, Na Xu, Yan Wang, Guixia Ling, Peng Zhang · 2021 · Journal of Materials Chemistry B
  90. Integration of mesenchymal stem cells with nanobiomaterials for the repair of myocardial infarction
    Jin Han, Jooyeon Park, Byung‐Soo Kim · 2015 · Advanced Drug Delivery Reviews
  91. pH-Sensitive Multi-PEGylated Block Copolymer as a Bioresponsive pDNA Delivery Vector
    Tsz Chung Lai, Younsoo Bae, Takayuki Yoshida, Kazunori Kataoka, Glen S. Kwon · 2010 · Pharmaceutical Research
  92. Enhanced Intravenous Transgene Expression in Mouse Lung Using Cyclic-Head Cationic Lipids
    Bharat Kumar Majeti, Rajkumar Sunil Singh, Sudheer Kumar Yadav · 2004 · Chemistry & Biology
  93. Nanoparticles‐Assisted Stem Cell Therapy for Ischemic Heart Disease
    Kai Zhu, ­Jun Li­, Yulin Wang, Hao Lai, Chunsheng Wang · 2015 · Stem Cells International
  94. A Bacteria Deriving Peptide Modified Dendrigraft Poly- l -lysines (DGL) Self-Assembling Nanoplatform for Targeted Gene Delivery
    Yang Liu, Xi He, Yuyang Kuang, Sai An, Chenyu Wang, Yubo Guo, Haojun Ma, Jinning Lou, Chen Jiang · 2014 · Molecular Pharmaceutics
  95. A novel tetracycline-controlled transactivator–transrepressor system enables external control of oncolytic adenovirus replication
    Henry Fechner, X Wang, Mahmoud A. Srour, Ulrike Siemetzki, Holger Seltmann, Andreas P. Sutter, Hans Scherübl, Christos C. Zouboulis, R. Schwaab, Wolfgang Hillen et al. · 2003 · Gene Therapy
  96. Target Gene Therapy for α-Fetoprotein-Producing Hepatocellular Carcinoma by E1B55k-Attenuated Adenovirus
    Makoto Ohashi, Fumihiko Kanai, Keisuke Tateishi · 2001 · Biochemical and Biophysical Research Communications
  97. Ex Vivo Magnetofection With Magnetic Nanoparticles: A Novel Platform for Nonviral Tissue Engineering
    Shieh‐Yueh Yang, Jui‐Sheng Sun, Cheng‐Heng Liu, Yang‐Hwei Tsuang, Li‐Ting Chen, Chin‐Yih Hong, Hong‐Chang Yang, H. E. Horng · 2008 · Artificial Organs
  98. Visible and near infrared resonance plasmonic enhanced nanosecond laser optoporation of cancer cells
    Bastien St-Louis Lalonde, Étienne Boulais, Jean‐Jacques Lebrun · 2013 · Biomedical Optics Express
  99. Cationic Gemini Surfactants Based on Tartaric Acid: Synthesis, Aggregation, Monolayer Behaviour, and Interaction with DNA
    Peter J. J. A. Buijnsters, Cristina L. García Rodríguez, Egon Willighagen · 2002 · European Journal of Organic Chemistry
  100. Purification of adenovirus and adeno-associated virus: comparison of novel membrane-based technology to conventional techniques
    Aoife M. Duffy, Aideen O’Doherty, Timothy O’Brien, Pádraig Strappe · 2005 · Gene Therapy