Polyglutamine expansion down-regulates specific neuronal genes before pathologic changes in SCA1

Lin, Xi, Antalffy, Barbara, Kang, Dongcheul, Orr, Harry T., Zoghbi, Huda Y.·2000·Nature Neuroscience

Cited by (374)

Items 301–374 of 374

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    Joakim Iver Post, Trygve Brauns Leergaard, Veronika Ratz, Sven Ivar Walaas, Stephan von Hörsten, Lise Sofie Haug Nissen‐Meyer · 2019 · Journal of Huntington s Disease
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  5. Investigation of the Influence of TBP CAG/CAA Repeats in Conjunction with HTT CAG Repeats on Huntington’s Disease Age at Onset in a Brazilian Sample
    Iane dos Santos da Silva, Thays Andrade Apolinário, Luciana de Andrade Agostinho, Carmen Lúcia Antão Paiva · 2022 · Journal of Molecular Neuroscience
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  9. Alterations of Store-Operated Calcium Entry in Neurodegenerative Pathologies: History, Facts, and Prospects
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  10. Neurodegenerative Diseases: Insights from Drosophila and Mouse Models
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    Jean‐Marc Gallo, P. Nigel Leigh · 2007 · Handbook of clinical neurology
  12. Epigenetics, Stem Cells, Cellular Differentiation, and Associated Hereditary Neurological Disorders
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  20. Molecular Genetics and Inherited Ataxias: Redefining Phenotypes and Pathogenesis
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  23. Immunohistochemical Localisation of Tata-Binding Protein in Huntington’s Disease Cortex
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  26. Chapter IX Mapping neuropathology with inducible and constitutive transcription factors
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  27. Anti-Excitotoxic and Antioxidant TGF-Beta Family Neurotrophic Factors: In Vitro Screening Models of Motor Neuron Degeneration
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  28. Chapter 17 Kennedy's Disease
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  29. Application of a Drosophila model to study Huntington's disease pathogenesis in vivo
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  30. Polyglutamine Aggregates as a Model for Protein‐misfolding Diseases
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  31. Targeting Protein Quality Control Pathways in Spinal and Bulbar Muscular Atrophy
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  32. Computational analysis of ataxin proteins: new insight into their functional performance and ataxia development
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  35. Dynamics of ataxin-1 in spinocerebellar ataxia type 1
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  36. Characterization of Pathogenesis of SCA17 Transgenic Mice
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  37. Bioenergetic Defects and Oxidative Damage in Transgenic Mouse Models of Neurodegenerative Disorders
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  38. Gene therapies for spinocerebellar ataxia type 1
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  39. Impairment of Cellular Transcriptional Machinery in Poly(Q) Disorders
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  40. The role of the ubiquitin-proteasome system in neurodegenerative disorders
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  41. Lossof-IIISpectrinLeadstoPurkinjeCellDysfunction RecapitulatingtheBehaviorandNeuropathologyof SpinocerebellarAtaxiaType5inHumans
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  43. Molecular and genetic characterization of spinocerebellar ataxia type 5 (SCA5)
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  44. Identification and caracterization of ataxin-3 Molecular Interactors.
    Anabela Ferro · 2009
  45. Spinocerebellar ataxia 1: case and cohort-based studies in India
    Dhanya Kumaran, Gaiti Hasan · 2015 · Current Science
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    Paul F. Worth · 2002 · OpenGrey (Institut de l'Information Scientifique et Technique)
  47. Animal Models of Spinocerebellar Ataxia Type 1
    Puneet Opal, Harry T. Orr · 2014 · Elsevier eBooks
  48. Genetic and molecular mechanisms underlying spinocerebellar ataxias
    Justyna Jezierska · 2013 · University of Groningen research database (University of Groningen / Centre for Information Technology)
  49. Phosphorylation of Ataxin-1: A Link Between Basic Research and Clinical Application in Spinocerebellar Ataxia Type 1
    Kerri M. Carlson, Harry T. Orr · 2006 · Elsevier eBooks
  50. Pathogenesis of Spinocerebellar Ataxia Type 7: New Insights from Mouse Models and Ataxin-7 Function
    Dominique Helmlinger, Didier Devys · 2006 · Elsevier eBooks
  51. The Hereditary Ataxias
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  54. Dendritic Excitability and Protein Kinase C Activity Regulate Purkinje Neuron Dendrite Degeneration in Cerebellar Ataxia
    Ravi Chopra · 2020 · Deep Blue (University of Michigan)
  55. Differential effects of Wnt-β-catenin signaling in Purkinje cells and Bergmann glia in SCA1
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  56. Nervous System
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  57. Autosomal Dominant Spinocerebellar Ataxias and Episodic Ataxias
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  58. The molecular genetics of the spinocerebellar ataxias
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  59. Motor Circuit Abnormalities During Cerebellar Development
    Elizabeth P. Lackey, Alejandro G. Rey Hipolito, Roy V. Sillitoe · 2023 · Contemporary clinical neuroscience
  60. Recent Advancements in Targeted Delivery of Therapeutic Molecules in Neurodegenerative Disease–-Spinocerebellar Ataxia–-Opportunities and Challenges
    Satya Prakash, Meenakshi Malhotra · 2008 · Drug Target Insights
  61. Increased intrinsic membrane excitability is associated with hypertrophic olivary degeneration in spinocerebellar ataxia type 1
    Logan M Morrison, Haoran Huang, Hillary P. Handler, Min Fu, David D. Bushart, Samuel S. Pappas, Harry T. Orr, Vikram G. Shakkottai · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  62. Increased intrinsic membrane excitability is associated with olivary hypertrophy in spinocerebellar ataxia type 1
    Logan M Morrison, Haoran Huang, Hillary P. Handler, Min Fu, Deborah M. Jones, David D. Bushart, Samuel S. Pappas, Harry T. Orr, Vikram G. Shakkottai · 2024 · Human Molecular Genetics
  63. Alterations in store-operated calcium entry in neurodegenerative pathologies: history, facts, perspectives
    Vladimir A. Vigont, Elena V. Kaznacheyeva · 2024 · Биологические мембраны Журнал мембранной и клеточной биологии
  64. Clinical, laboratory, and genetic studies of families with Charcot-Marie-Tooth type 2C disease
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  65. Protein complexes in neurodegenerative diseases
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  66. Additional file 1 of Missense mutations in ITPR1 cause autosomal dominant congenital nonprogressive spinocerebellar ataxia
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  67. Additional file 2 of Missense mutations in ITPR1 cause autosomal dominant congenital nonprogressive spinocerebellar ataxia
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  68. Additional file 3 of Missense mutations in ITPR1 cause autosomal dominant congenital nonprogressive spinocerebellar ataxia
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  70. Dérégulation de la signalisation non génomique du récepteur aux androgènes dans un modèle SBMA in vitro
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  71. Molecular basis of transcriptional dysregulations in the spinocerebellar ataxia type 7, a neurodegenerative polyglutamine disorder
    Antoine Hache · 2020 · theses.fr (ABES)
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