Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts

Paloneva, Juha, Kestilä, Marjo, Wu, Jun, Salminen, Antti, Böhling, Tom, Ruotsalainen, Vesa, Hakola, Panu, Bakker, Alexander B.H. +5 more·2000·Nature Genetics
DOI 10.1038/77153

Cited by (462)

Items 301–400 of 462

  1. Microglia in physiological conditions and the importance of understanding their homeostatic functions in the arcuate nucleus
    Mara A. Guzmán‐Ruiz, Natalí N Guerrero Vargas, Ricardo Jair Ramírez Carreto, Juan Carlos González-Orozco, Bryan Adair Torres-Hernández, Michelle Valle-Rodríguez, Rosalinda Guevara‐Guzmán, Anahí Chavarría · 2024 · Frontiers in Immunology
  2. Analysis of dementia-related gene variants in APOE ε4 noncarrying Korean patients with early-onset Alzheimer's disease
    Jong Eun Park, Hee Jin Kim, Young-Eun Kim, Hyemin Jang, Soo Hyun Cho, Seung Joo Kim, Duk Lyul Na, Hong‐Hee Won, Chang‐Seok Ki, Sang Won Seo · 2019 · Neurobiology of Aging
  3. Pathologic basis of the preferential thinning of thecorpus callosum in adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP)
    Michiaki Kinoshita, Kiyomitsu Oyanagi, Yasufumi Kondo, Keisuke Ishizawa, Kenji Ishihara, Mari Yoshida, Teruhiko Inoue, Yoshio Mitsuyama, Kunihiro Yoshida, Mitsunori Yamada et al. · 2021 · eNeurologicalSci
  4. Osteopetroses and immunodeficiencies in humans
    ANNA MARIA VILLA, Paolo Vezzoni, Annalisa Frattini · 2006 · Current Opinion in Allergy and Clinical Immunology
  5. The lipid-sensor TREM2 aggravates disease in a model of LCMV-induced hepatitis
    Lindsay Kosack, Riem Gawish, Alexander Lercher, Bojan Vilagos, Anastasiya Hladik, Karin Lakovits, Anannya Bhattacharya, Christopher Schliehe, Ildikó Mesteri, Sylvia Knapp et al. · 2017 · Scientific Reports
  6. Characterization of Genetic Networks Associated with Alzheimer’s Disease
    Bin Zhang, Linh My Tran, Valur Emilsson, Jun Zhu · 2015 · Methods in molecular biology
  7. CSF1R Mutation p.G589R and the Distribution Pattern of Brain Calcification
    Kensuke Daida, Kenya Nishioka, Yuanzhe Li, Sho Nakajima, Ryota Tanaka, Nobutaka Hattori · 2017 · Internal Medicine
  8. Specific microglial phagocytic phenotype and decrease of lipid oxidation in white matter areas during aging: Implications of different microenvironments
    Paula Sanchez-Molina, Beatriz Almolda, Núria Benseny‐Cases, Berta González, Alex Perálvarez‐Marín, Bernardo Castellano · 2021 · Neurobiology of Aging
  9. A novel compound heterozygous mutation in the DAP12 gene in a patient with Nasu-Hakola disease
    Ryo Kuroda, Jun‐ichi Satoh, Takashi Yamamura, Toshiharu Anezaki, Tatsuhiro Terada, Kinya Yamazaki, Tomokazu Obi, Kouichi Mizoguchi · 2006 · Journal of the Neurological Sciences
  10. An Italian family with Nasu-Hakola disease
    Andrea Salmaggi, Elio Maccagnano, Anna Maria Musso, L. Di Lena, Juha Paloneva, Amerigo Boiardi · 2003 · Journal of Neurology
  11. Diseases of movement and system degenerations
    Paul G. Ince, Brent Clark, Janice L. Holton, Tamás Révész, Stephen B. Wharton · 2008 · CRC Press eBooks
  12. A Japanese Case with Nasu-Hakola Disease of DAP12 Gene Mutation Exhibiting Precuneus Hypoperfusion
    Kiyotaka Nakamagoe, Ayako Shioya, Tetsuto Yamaguchi, Hiroyuki Takahashi, Reiko Koide, Tatsuya Monzen, Jun‐ichi Satoh, Akira Tamaoka · 2011 · Internal Medicine
  13. Brain–Bone Axis in Physiological and Pathological Conditions
    Luca Massaccesi, Massimiliano Marco Corsi Romanelli, Emanuela Galliera · 2025 · International Journal of Molecular Sciences
  14. Construction of a microenvironment immune gene model for predicting the prognosis of endometrial cancer
    Yichen Wang, Jingkai Zhang, Yijun Zhou, Zhiguang Li, Dekang Lv, Quentin Liu · 2021 · BMC Cancer
  15. Reconstructing directed gene regulatory network by only gene expression data
    Lu Zhang, Xikang Feng, Yen Kaow Ng, Shuai Cheng Li · 2016 · BMC Genomics
  16. Transcriptome Profiling in the Hippocampi of Mice with Experimental Autoimmune Encephalomyelitis
    Poornima D. E. Weerasinghe-Mudiyanselage, Sohi Kang, Joong‐Sun Kim, Jong-Choon Kim, Sung‐Ho Kim, Hongbing Wang, Taekyun Shin, Changjong Moon · 2022 · International Journal of Molecular Sciences
  17. Unveiling the transcriptome alteration of POMC neuron in diet-induced obesity
    Peng Lyu, Zhishun Huang, Qingjun Feng, Yongfu Su, Mengying Zheng, Yannv Hong, Xiang Cai, Zhonglei Lu · 2020 · Experimental Cell Research
  18. Nasu-Hakola disease: a rare entity in Italy. Critical review of the literature.
    Lorenza Montalbetti, Debora Soragna, Maria Teresa Ratti, Paola Bini, Simona Buscone, Arrigo Moglia · 2004 · PubMed
  19. A clinicopathological and genetic study of sporadic diffuse leukoencephalopathy with spheroids: a report of two cases
    Takanori Kimura, Keisuke Ishizawa, Takashi Mitsufuji, Tohru Abe, Y. Nakazato, Kunihiro Yoshida, Atsushi Sasaki, Nobuo Araki · 2013 · Neuropathology and Applied Neurobiology
  20. Gray matter lesions in Nasu-Hakola disease: A report on three autopsy cases
    Naoya Aoki, Kuniaki Tsuchiya, Takashi Togo, Zen Kobayashi, Hirotake Uchikado, Omi Katsuse, Kyoko Suzuki, Hiroshige Fujishiro, Tetsuaki Arai, Eizo Iseki et al. · 2010 · Neuropathology
  21. Unraveling the Bone–Brain Communication Network
    Surajit Hansda, Hiranmoy Das · 2025 · Biology
  22. Lipomembranous fat necrosis: A distinctive and unique morphology (Review)
    Susumu Matsukuma, Ayano Matsunaga, Oh Takahashi, Sho Ogata · 2022 · Experimental and Therapeutic Medicine
  23. Monoallelic TYROBP deletion is a novel risk factor for Alzheimer’s disease
    Henna Martiskainen, Roosa-Maria Willman, Päivi Harju, Sami Heikkinen, Mette Heiskanen, Stephan A. Müller, Rosa Sinisalo, Mari Takalo, Petra M. Mäkinen, Teemu Kuulasmaa et al. · 2025 · Molecular Neurodegeneration
  24. Microglial phagocytosis in epilepsy: Mechanisms and impact
    Abhijeet S. Barath, Long‐Jun Wu · 2025 · The Journal of Physiology
  25. Microglia in Alzheimer’s Disease: A Favorable Cellular Target to Ameliorate Alzheimer’s Pathogenesis
    Dewan Md. Sumsuzzman, Md. Sahab Uddin, Md. Tanvir Kabir, Sharifa Hasana, Asma Perveen, Ibtesam S. Alanazi, Ghadeer Mohsen Albadrani, Mohamed M. Abdel‐Daim, Ghulam Md Ashraf · 2022 · Mediators of Inflammation
  26. Elucidation of the molecular interactions that enable stable assembly and structural diversity in multicomponent immune receptors
    Lam‐Kiu Fong, Matthew J. Chalkley, Sophia K. Tan, Michael Grabe, William F. DeGrado · 2021 · Proceedings of the National Academy of Sciences
  27. Synapse Regulation
    Haley A. Vecchiarelli, Luana Tenorio Lopes, Rosa Chiara Paolicelli, Beth Stevens, Hiroaki Wake, Marie‐Ève Tremblay · 2024 · Advances in neurobiology
  28. A proteomics approach to study mouse long bones: examining baseline differences and mechanical loading-induced bone formation in young-adult and old mice
    Christopher J. Chermside‐Scabbo, John T. Shuster, Petra Erdmann-Gilmore, Eric Tycksen, Qiang Zhang, R. Reid Townsend, Matthew J. Silva · 2024 · Aging
  29. Headmasters: Microglial regulation of learning and memory in health and disease
    Laetitia Weinhard, Paolo d’Errico, Tuan Leng Tay · 2018 · AIMS molecular science
  30. Overexpression of miR-101 May Target DUSP1 to Promote the Cartilage Degradation in Rheumatoid Arthritis
    Yan Ye, Chunde Bao, Wei Fan · 2019 · Journal of Computational Biology
  31. Regulation of Osteoclast Activity
    Roland Baron, William C. Horne · 2005 · Springer eBooks
  32. No evidence for shared etiology in two demyelinative disorders, MS and PLOSL
    Anna-Maija Sulonen, Suvi P. Kallio, Pekka Ellonen, Minna H. Suvela, Irina Elovaara, Keijo J. Koivisto, Tuula Pirttilä, Mauri Reunanen, Pentti J. Tienari, Aarno V. Palotie et al. · 2008 · Journal of Neuroimmunology
  33. Induction of Golli-MBP Expression in CNS Macrophages During Acute LPS-Induced CNS Inflammation and Experimental Autoimmune Encephalomyelitis (EAE)
    Tracey L. Papenfuss, J. Cameron Thrash, Patricia E. Danielson, Pamela E. Foye, Brian S. Hllbrush, J. Gregor Sutcliffe, Caroline C. Whitacre, Monica J. Carson · 2007 · The Scientific World JOURNAL
  34. An Introduction to CNS-Resident Microglia: Definitions, Assays, and Functional Roles in Health and Disease
    Deirdre S. Davis, Monica J. Carson · 2012 · Springer eBooks
  35. Bone matrix hypermineralization associated with low bone turnover in a case of Nasu-Hakola disease
    Mohammad Shboul, Paul Roschger, Rudolf Ganger, Lefteris Paschalis, Stamatia G. Rokidi, Shahin Zandieh, Jana Behunova, Christian Muschitz, Astrid Fahrleitner‐Pammer, Alvin Yu Jin Ng et al. · 2018 · Bone
  36. Leucoencéphalopathies génétiques de l’adulte
    Frédéric Sedel, Ayman Tourbah, Nicole Baumann, Bertrand Fontaine, Patrick R. Aubourg, Catherine Lubetzki, Olivier Lyon‐Caen · 2005 · Revue Neurologique
  37. DAP12 ITAM Motif Regulates Differentiation and Apoptosis in M1 Leukemia Cells
    Naoko Aoki, Shoji Kimura, Kensuke Oikawa, Hitoshi Nochi, Yoshiaki Atsuta, Hiroya Kobayashi, Keisuke Sato, Makoto Katagiri · 2002 · Biochemical and Biophysical Research Communications
  38. DAP12 deletion reduces neuronal SLIT2 and demyelination and enhances brain resilience in female tauopathy mice
    Hao Chen, Li Fan, Qi Guo, Man Ying Wong, Jingjie Zhu, Nessa R. Foxe, Winston T. Wang, Aviram Nessim, Gillian Carling, Bangyan Liu et al. · 2025 · Molecular Neurodegeneration
  39. Trem2 Enhances Demyelination in the Csf1r+/− Mouse Model of Leukoencephalopathy
    Fabrizio Biundo, Violeta Chiţu, Şölen Gökhan, Edward Chen, Jude Oppong‐Asare, E. Richard Stanley · 2023 · Biomedicines
  40. Multiomics analyses reveal pathological mechanisms of HBV infection and integration in liver cancer
    Mengbiao Guo, Linghao Zhao, Chen Jiang, Changchang Jia, Hui Liu, Weiping Zhou, Zhou Songyang, Yuanyan Xiong · 2023 · Journal of Medical Virology
  41. Spleen tyrosine kinase suppresses osteoblastic differentiation through MAPK and PKCα
    Kiyoshi Yoshida, Chikahisa Higuchi, Akio Nakura, Hideki Yoshikawa · 2011 · Biochemical and Biophysical Research Communications
  42. DAP12 Overexpression Induces Osteopenia and Impaired Early Hematopoiesis
    Geneviève Despars, Subramanya N. M. Pandruvada, Adrienne Anginot, Chantal Domenget, Pierre Jurdic, M. Mazzorana · 2013 · PLoS ONE
  43. Microglia: A CNS-Specific Tissue Macrophage
    Shweta S. Puntambekar, Jonathan M. Doose, Monica J. Carson · 2007 · Springer eBooks
  44. Intrapulmonary, Adenovirus-Mediated Overexpression of KARAP/DAP12 Enhances Fungal Clearance during Invasive Aspergillosis
    Kristin J. Carpenter, Karen F. Buckland, Zhou Xing, Cory M. Hogaboam · 2005 · Infection and Immunity
  45. Primary microgliopathy presenting as degenerative dementias: A case series of novel gene mutations from India
    Subasree Ramakrishnan, Faheem Arshad, Keerthana Bs, Arun Gokul Pon, Susan Bosco, Sandeep Kumar, Hariharakrishnan Chidambaram, Subhash Chandra Bose Chinnathambi, Karthik Kulanthaivelu, Gautham Arunachal et al. · 2024 · Dementia and Geriatric Cognitive Disorders Extra
  46. Intracellular Signaling by the Killer Immunoglobulin-Like Receptors and Ly49
    Daniel W. McVicar, Deborah N. Burshtyn · 2001 · Science Signaling
  47. Macrophage transplantation rescues RNASET2-deficient leukodystrophy by replacing deficient microglia in a zebrafish model
    Holly A. Rutherford, Diogo Candeias, Christopher James Arthur Duncan, Stephen A. Renshaw, Noémie Hamilton · 2024 · Proceedings of the National Academy of Sciences
  48. Systematic analysis of TREM2 and its carcinogenesis in pancreatic cancer
    Wanting Zheng, Wangjianfei Yu, Ruheng Hua, Jun He, Nuwa Wu, Siyun Tian, Wentao Huang, Qin L · 2024 · Translational Cancer Research
  49. The microglial innate immune receptor TREM2 participates in fear memory formation through excessive prelimbic cortical synaptic pruning
    Lele Zhang, Cheng Peng, Yuan-qing Chu, Zi-ming Zhou, Rong Hua, Yongmei Zhang · 2024 · Frontiers in Immunology
  50. CLEC4C p.K210del variant causes impaired cell surface transport in plasmacytoid dendritic cells of amyotrophic lateral sclerosis
    Su Min Lim, Young-Eun Kim, Won Jun Choi, Ki‐Wook Oh, Min‐Young Noh, Min‐Soo Kwon, Minyeop Nahm, Namshin Kim, Chang‐Seok Ki, Seung Hyun Kim · 2016 · Oncotarget
  51. Cross-species high-resolution transcriptome profiling suggests biomarkers and therapeutic targets for ulcerative colitis
    Reza Yarani, Oana Palasca, Nadezhda T. Doncheva, Christian Anthon, Bartosz Pilecki, Cecilie Amalie Brøgger Svane, Aashiq Hussain Mirza, Thomas Litman, Uffe Holmskov, Claus Heiner Bang‐Berthelsen et al. · 2023 · Frontiers in Molecular Biosciences
  52. Computational saturation mutagenesis to explore the effect of pathogenic mutations on extra-cellular domains of TREM2 associated with Alzheimer’s and Nasu-Hakola disease
    Preety Sthutika Swain, Sunita Panda, Sanghamitra Pati, Budheswar Dehury · 2023 · Journal of Molecular Modeling
  53. The PDGFR Receptor Family
    Violeta Chiţu, Cristina I. Caescu, E. Richard Stanley, Johan Lennartsson, Lars Rönnstrand, Carl‐Henrik Heldin · 2015 · Springer eBooks
  54. A Case of Nasu-Hakola Disease without Fractures or Consanguinity Diagnosed Using Exome Sequencing and Treated with Sodium Valproate
    Kiyohiro Yamazaki, Yuta Yoshino, Yoko Mori, Shinichiro Ochi, Taku Yoshida, Takashi Ishimaru, Shuichi Ueno · 2015 · Clinical Psychopharmacology and Neuroscience
  55. The Osteoclast
    Roberta Faccio, Yongwon Choi, Steven L. Teitelbaum, Hiroshi Takayanagi · 2010 · Elsevier eBooks
  56. Psychosis associated with leukodystrophies
    Patricia I. Rosebush, Rebecca Anglin, Michael F. Mazurek · 2010 · Cambridge University Press eBooks
  57. Involvement of semaphorins and their receptors in neurological diseases
    Noriko Takegahara, Atsushi Kumanogoh · 2010 · Clinical and Experimental Neuroimmunology
  58. Bioinformatics analysis indicates that microRNA‑628‑5p overexpression may alleviate Alzheimer's disease by targeting TYROBP
    Miao Liu, Shuling Li, Chun Ma, Xinna Wang, Shuang Yu, Haining Lin, Zhiying Guan, Lihua Yang · 2020 · Molecular Medicine Reports
  59. Regional cerebral blood flow in a patient with Nasu-Hakola disease
    Tohru Takeshita, Tatsuro Kaminaga, Tomoko Tatsumi, Yuki Hatanaka, Shigeru Furui · 2005 · Annals of Nuclear Medicine
  60. Modes of participation of macrophages in the formation of membranocystic lesions
    Toshitsugu Nakamura, Masayuki Fujiwara · 2002 · Apmis
  61. Heterozygous TYROBP deletion (PLOSLFIN) is not a strong risk factor for cognitive impairment
    Karri Kaivola, Lilja Jansson, Elmo Saarentaus, Anna Kiviharju, Ville Juhani Rantalainen, Johan Gunnar Eriksson, Timo E. Strandberg, Tuomo M. Polvikoski, Liisa Myllykangas, Pentti J. Tienari · 2017 · Neurobiology of Aging
  62. A virus finds its natural killer
    Jean‐Laurent Casanova, Emmanuelle Jouanguy, Laurent Abel · 2001 · Nature Genetics
  63. Screening and Identification of Key Biomarkers in Lower Grade Glioma via Bioinformatical Analysis
    Fangzhou Guo, Jun Yan, Guoyuan Ling, Hainan Chen, Qianrong Huang, Junbo Mu, Ligen Mo · 2022 · Applied Bionics and Biomechanics · Retracted
  64. The Downregulation of ITGAX Exacerbates Amyloid-β Plaque Deposition in Alzheimer’s Disease by Increasing Polarization of M1 Microglia
    Yufei Hu, Xupeng Wang, Zijun Zhao, Menglin Liu, Xiao‐Qin Ren, Xiao‐Hui Xian, Chunxiao Liu, Qiujun Wang · 2024 · Journal of Alzheimer s Disease
  65. Oligodendrocyte: Structure, Function and Pathology
    Nisha Patro, Ishan Kumar Patro, Poonam Tandon · 2022 · Springer eBooks
  66. DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity
    Wenjie Luo, Hao Chen, Li Fan, Qi Guo, Man Ying Wong, Fangmin Yu, Nessa R. Foxe, Winston T. Wang, Aviram Nessim, Gillian Carling et al. · 2023 · Research Square
  67. Monoallelic TYROBP deletion is a novel risk factor for Alzheimer’s disease
    Henna Martiskainen, Roosa-Maria Willman, Sami Heikkinen, Stephan A. Müller, Rosa Sinisalo, Mari Takalo, Petra M. Mäkinen, Teemu Kuulasmaa, Viivi Pekkala, Ana Galván del Rey et al. · 2024 · medRxiv
  68. Homozygous mutation in CSF1R causes brain abnormalities, neurodegeneration, and dysosteosclerosis (BANDDOS)
    Hossein Daghagh, Haniyeh Rahbar Kafshboran, Yousef Daneshmandpour, Maryam Nasiri Aghdam, Shahrzad Talebian, Jafar Nouri Nojadeh, Hamid Hamzeiy, Saskia Biskup, Ebrahim Sakhinia · 2022 · Bioimpacts
  69. Detecting the Unusual: Natural Killer Cells
    Armin Volz, Britta Radeloff · 2006 · Progress in nucleic acid research and molecular biology
  70. Origin and Development of Microglia
    Nisha Patro, Ishan Kumar Patro · 2022 · Springer eBooks
  71. Frontotemporal-TDP and LATE Neurocognitive Disorders: A Pathophysiological and Genetic Approach
    Genaro Gabriel Ortíz, Luis Javier Ramírez-Jirano, Raúl L. Arizaga, Daniela L. C. Delgado-Lara, Erandis D. Torres-Sánchez · 2023 · Brain Sciences
  72. Membranous lipodystrophy: skeletal findings on CT and MRI
    Ogonna Kenechi Nwawka, Robert J. Schneider, Manjula Bansal, Douglas N. Mintz, Joseph M. Lane · 2014 · Skeletal Radiology
  73. Rorschach assessment of personality functioning in patients with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy
    Tuula Ilonen, Panu Hakola, Matti Vanhanen, Jari Tiihonen · 2011 · Acta Neuropsychiatrica
  74. The C9ORF72 expansion does not affect the phenotype in Nasu-Hakola disease with the DAP12 mutation
    Eino Solje, Päivi H. Hartikainen, Miko Valori, Ritva L. Vanninen, Jari Tiihonen, Panu Hakola, Pentti J. Tienari, Anne Marja Remes · 2014 · Neurobiology of Aging
  75. Risk Factors for Alzheimer’s Disease
    A. A. Farooqui · 2017 · Elsevier eBooks
  76. Finnish neuroscience from past to present
    Esa R. Korpi, Dan Lindholm, Pertti Panula, Pentti J. Tienari, Matti Haltia · 2020 · European Journal of Neuroscience
  77. Gene Mapping and Human Disease
    Joseph Douglas Terwilliger · 2022 · Springer eBooks
  78. Maladies démyélinisantes d’origine génétique
    Pierre M. Labauge, Odile Boespflug‐Tanguy · 2010 · La Presse Médicale
  79. Neurodegeneration and the Ordered Assembly of Tau
    Michel Goedert · 2018 · Elsevier eBooks
  80. Neuroinflammation in Neurological Disorders
    Jun‐ichi Kira · 2013 · Advances in neurobiology
  81. Human monocyte‐derived microglia‐like ( iMG ) cells: A tool to explore microglial dynamics
    Sota Kyuragi, Shogo Inamine, Masahiro Ohgidani, Takahiro A. Kato · 2024 · Clinical and Experimental Neuroimmunology
  82. Reconstructing directed gene regulatory network by only gene expression data
    Lu Zhang, Yen Kaow Ng, Shuai Cheng Li · 2015 · IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
  83. Nasu-Hakola Disease as Suspected Cause for Bone Disease and Dementia
    Maryam Sahebari, Bita Abbasi, Ali Akhondpour Manteghi, Nafiseh Abdollahi · 2014 · JCR Journal of Clinical Rheumatology
  84. TRAPC : A novel Triggering Receptor expressed on Antigen Presenting Cells
    Rutger van der Holst · 2007 · Figshare
  85. Identification of the Meckel syndrome gene (MKS1) exposes a novel ciliopathy
    Mira Kyttälä · 2006 · Työväentutkimus Vuosikirja
  86. Transcriptome profiling of ulcerative colitis mouse model suggests biomarkers and therapeutic targets for human colitis
    Reza Yarani, Oana Palasca, Nadezhda T. Doncheva, Christian Anthon, Bartosz Pilecki, Cecilie Amalie Brøgger Svane, Aashiq Hussain Mirza, Thomas Litman, Uffe Holmskov, Claus Heiner Bang‐Berthelsen et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  87. The microglia receptor protein TREM2 is essential for protective innate immune responses against herpesvirus infection in the brain
    Stefanie Fruhwürth, Line Sinnathamby Reinert, Carl Öberg, Marcelina Sakr, Marcus Henricsson, Henrik Zetterberg, Søren R. Paludan · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  88. Impaired microglial TYROBP/DAP12 signaling exacerbates cortical cholinergic and noradrenergic axonal degeneration in Aβ amyloidosis
    Yu Hirota, Jun Yamamoto, Sho Takatori, Yasufumi Sakakibara, Kimi Takei, 佐治多美子, Michiko Sekiya, Taisuke Tomita, Koichi Iijima · 2026 · Molecular Neurodegeneration Advances
  89. Harnessing Microglial Repopulation: From Inflammatory Drivers to Therapeutic Allies in CNS Diseases
    Guanyu Li, Hong Liu, Zhida Lan, Y Z Yuan, J R Li, Ziwei Dai, Chao Huang, Cheng He, Shangyao Qin, Zhida Su · 2026 · Glia
  90. Microglial ITAM & ITIM Signaling in Neurodegenerative Disease and Brain Aging
    Aman Mangalmurti, Amelia Bonheur, John R. Lukens · 2026 · Journal of Molecular Biology
  91. Microglial TDP-43 mediates myelin refinement and represses Tyrobp cryptic exon inclusion in mice
    Anne‐Claire Compagnion, Andranik Ivanov, Anil Rana, Felipe I. Espinoza, Thomas Sandmann, Fanny Sandrine Martineau, Katia Monsorno, Roberta Facchinetti, Alessandro Matera, Lionel Rougé et al. · 2026 · Nature Neuroscience
  92. The genetics of frontotemporal dementia
    John Hardy, Parastoo Momeni, Amanda Myers, Bryan J. Traynor · 2006 · CRC Press eBooks
  93. 43‐year‐old‐man presenting repeated pathologic fractures of limbs, dementia and grand mal
    Naoji Amano · 2002 · Neuropathology
  94. Molecular Mechanisms of Synaptic Plasticity and Memory and Their Dysfunction in Alzheimer's Disease ☆
    Gabriel S. Stephens, Jason C. You, Chia-Hsuan Fu, Jeannie Chin · 2017 · Elsevier eBooks
  95. Identification of Key Pathways and Genes in Dementia via Integrated Bioinformatics Analysis
    Basavaraj Mallikarjunayya Vastrad, Chanabasayya Mallikarjunayya Vastrad · 2025 · SN Comprehensive Clinical Medicine
  96. Microglial Ontogeny and Functions in Shaping Brain Circuits
    Guillaume Hoeffel, Paola Squarzoni, Sonia Garel, Florent Ginhoux · 2014 · Springer eBooks
  97. Trem2 Variants and Risk of Alzheimer’s Disease
    Perez Martinez David Andres · 2014 · Brain Disorders & Therapy
  98. Developmental stages and pathways of NK cell maturation
    Bartosz J. Grzywacz, Jeffery S. Miller, Michael R. Verneris · 2010 · Elsevier eBooks
  99. Innate Immunity Signaling
    Tsuneya Ikezu · 2016 · Springer eBooks
  100. Alzheimer’s Disease
    Tsuneya Ikezu · 2016 · Springer eBooks