Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts

Paloneva, Juha, Kestilä, Marjo, Wu, Jun, Salminen, Antti, Böhling, Tom, Ruotsalainen, Vesa, Hakola, Panu, Bakker, Alexander B.H. +5 more·2000·Nature Genetics

DOI 10.1038/77153

Cited by (462)

Items 201–300 of 462

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Frank M. Cichocki, Ewa Sitnicka, Yenan T. Bryceson · 2014 · Seminars in Immunology
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Courtney L. Long, Mary Beth Humphrey · 2012 · BoneKEy Reports
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Hao Deng, Wen Li Zheng, Joseph J. Jankovic · 2015 · Ageing Research Reviews
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Yijing Zhou, Fengping Dong, Thomas A. Lanz, Veronica Reinhart, M Li, L Liu, J Zou, Hualin Simon Xi, Yingwei Mao · 2017 · Molecular Psychiatry
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Marco Colonna, Isaiah R. Turnbull, Julia Klesney‐Tait · 2007 · Advances in experimental medicine and biology
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Gaël Nicolas, Camille Charbonnier, Dominique Campion · 2016 · Human Heredity
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Lopez‐Atalaya, Jose P., Askew, Katharine E., Sierra, Amanda, Gomez‐Nicola, Diego · 2018 · Developmental Neurobiology
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Colonna, Marco · 2003 · Journal of Clinical Investigation
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Elysa M. Wolf, B. Fingleton, A. Hasty · 2022 · Frontiers in Oncology
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Masahiro Ohgidani, Takahiro A. Kato, Shigenobu Kanba · 2015 · Frontiers in Cellular Neuroscience
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Troy T. Rohn · 2013 · Oxidative Medicine and Cellular Longevity
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Ilaria Prada, Gabriela Naum-Onganı́a, Cecilia Buonsanti, Paola Panina‐Bordignon, Jacopo Meldolesi · 2006 · Neuroscience
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Nagihan Bostancı, Georgios N. Belibasakis · 2012 · FEMS Immunology & Medical Microbiology
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Zixuan Wang, Qi Wan, Ang Xing · 2020 · NeuroMolecular Medicine
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Faris Yaghmoor · 2014 · Journal of Alzheimer’s Disease & Parkinsonism
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Zhihong Chen, Lingkai Su, Qingan Xu, Jenny Katz, Suzanne M. Michalek, Mingwen Fan, Xu Feng, Ping Zhang · 2015 · Journal of Biological Chemistry
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John R. Webb, S H Lee, Silvia Marina Vidal · 2002 · Genes and Immunity
Compartmentalization of ITAM and integrin signaling by adapter molecules
Natalie Bezman, Gary A. Koretzky · 2007 · Immunological Reviews
Insights into NK cell biology from human genetics and disease associations
Stephanie M. Wood, Hans‐Gustaf Ljunggren, Yenan T. Bryceson · 2011 · Cellular and Molecular Life Sciences
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Jane P. F. Bai, Alexander V. Alekseyenko, Alexander Statnikov, I‐Ming Wang, Peggy H. Wong · 2013 · The AAPS Journal
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Huan Liao, Christine Klaus, Harald Neumann · 2020 · International Journal of Molecular Sciences
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S. Ishikawa · 2004 · International Immunology
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Frame, Gabrielle, Bretland, Katie A., Dengler-Crish, Christine M. · 2020 · Connective Tissue Research
Therapeutic Effect of Modulating TREM-1 via Anti-inflammation and Autophagy in Parkinson’s Disease
Chien‐Wei Feng, Nan‐Fu Chen, Chun‐Sung Sung, Hsiao‐Mei Kuo, San‐Nan Yang, Chien‐Liang Chen, Han-Chun Hung, Bing‐Hung Chen, Zhi‐Hong Wen, Wu-Fu Chen · 2019 · Frontiers in Neuroscience
Functional involvement of γ-secretase in signaling of the triggering receptor expressed on myeloid cells-2 (TREM2)
Konstantin Glebov, Patrick Wunderlich, Ilker Karaca, Jochen Walter · 2016 · Journal of Neuroinflammation
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Yvette Zarb, Sucheta Sridhar, Sina Nassiri, Sebastian G. Utz, Johanna Schaffenrath, Upasana Maheshwari, Elisabeth Jane Rushing, K. Peter R. Nilsson, Mauro Delorenzi, Marco Colonna et al. · 2021 · Science Advances
Critical Negative Regulation of Type 1 T Cell Immunity and Immunopathology by Signaling Adaptor DAP12 during Intracellular Infection
Maziar Divangahi, Tony Yang, Kapilan Kugathasan, Sarah M. McCormick, Shunsuke Takenaka, Gordon J. Gaschler, Ali A. Ashkar, Martin R. Stämpfli, Jack Gauldie, Jonathan L. Bramson et al. · 2007 · The Journal of Immunology
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Stefanie Fruhwürth, Line Sinnathamby Reinert, Carl Öberg, Marcelina Sakr, Marcus Henricsson, Henrik Zetterberg, Søren R. Paludan · 2023 · Science Advances
Glial cells and adaptive immunity in frontotemporal dementia with tau pathology
Iain James Hartnell, David L Blum, James A. R. Nicoll, Guillaume Dorothée, Delphine Boche · 2020 · Brain
CSF1R mutations identified in three families with autosomal dominantly inherited leukoencephalopathy
Jun Mitsui, Takashi Matsukawa, Hiroyuki Ishiura, Koichiro Higasa, Jun Yoshimura, Taro Saito, Budrul Ahsan, Yuji Takahashi, Jun Goto, Atsushi Iwata et al. · 2012 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
Hepatic gene expression profiling reveals perturbed calcium signaling in a mouse model lacking both LDL receptor and Apobec1 genes
Ranjan Dutta, Uma Singh, Tong-Bin Li, Myriam Fornage, Ba-Bie Teng · 2003 · Atherosclerosis
Hereditary diffuse leucoencephalopathy with spheroids
Nicole Hancock · 2003 · Journal of Neurology Neurosurgery & Psychiatry
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Alessandra Mirarchi, Elisabetta Albi, Tommaso Beccari, Cataldo Arcuri · 2023 · International Journal of Molecular Sciences
Treml4, an Ig Superfamily Member, Mediates Presentation of Several Antigens to T Cells In Vivo, Including Protective Immunity to HER2 Protein
Hiroaki Hemmi, Neeha Zaidi, Bei Wang, Ines Grazina de Matos, Christopher J. Fiorese, Ashira Lubkin, Lori D. Zbytnuik, Koji Suda, Kenneth Zhang, Masaki Noda et al. · 2011 · The Journal of Immunology
Microglia phagocytose oligodendrocyte progenitor cells and synapses during early postnatal development: implications for white versus gray matter maturation
Irfan, Muhammad, Evonuk, Kirsten S., DeSilva, Tara M. · 2022 · The FEBS Journal
Cardiac and skeletal muscles show molecularly distinct responses to cancer cachexia
Angie M. Y. Shum, David C. Y. Fung, Susan Corley, Max C. McGill, Nicholas L. Bentley, Timothy C. Tan, Marc Ronald Wilkins, Patsie Polly · 2015 · Physiological Genomics
Modulation of Hepatic Granulomatous Responses by Transgene Expression of DAP12 or TREM-1-Ig Molecules
Hitoshi Nochi, Naoko Aoki, Kensuke Oikawa, Mitsuru Yanai, Yumi Takiyama, Yoshiaki Atsuta, Hiroya Kobayashi, Keisuke Sato, Masatoshi Tateno, Takeo Matsuno et al. · 2003 · American Journal Of Pathology
Natural killer cells in the central nervous system
Zhiyuan Ning, Ying Liu, Daji Guo, Wei‐Jye Lin, Yamei Tang · 2023 · Cell Communication and Signaling
Variable expression of microglial DAP12 and TREM2 genes in Nasu-Hakola disease
Atsushi Sasaki, Akiyoshi Kakita, Kunihiro Yoshida, Takuya Konno, Takeshi Ikeuchi, Shintaro Hayashi, Hidenori Matsuo, Kei Shioda · 2015 · Neurogenetics
Insight into the role of phosphatidylserine in complement-mediated synapse loss in Alzheimer’s disease
Dimitra Sokolova, Thomas Childs, Soyon Youngae Hong · 2021 · Faculty Reviews
Immune Semaphorins: Increasing Members and Their Diverse Roles
Hitoshi Kikutani, Kazuhiro Suzuki, Atsushi Kumanogoh · 2007 · Advances in immunology
Database for the mutations of the Finnish disease heritage
Kati Sipilä, Perttì Aula · 2001 · Human Mutation
The Primary Microglial Leukodystrophies: A Review
Isidró Ferrer · 2022 · International Journal of Molecular Sciences
Non-pathological roles of microglial TREM2/DAP12: TREM2/DAP12 regulates the physiological functions of microglia from development to aging
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Philippe Petry, Alexander Oschwald, Katrin Kierdorf · 2023 · European Journal of Immunology
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Huiping Shi, Bojing Shao · 2023 · Cells
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Peter J. Amos, Susan Fung, Amanda Case, Jerusalem Kifelew, Leah Osnis, C S Smith, Kevin Green, Alipi V. Naydenov, Macarena S. Aloi, Jesse J. Hubbard et al. · 2017 · ASN NEURO
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Mullane, Kevin, Williams, Michael · 2018 · Biochemical Pharmacology
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Han, Jie, Wang, Miaomiao, Ren, Manru, Lou, Haiyan · 2017 · International Journal of Neuroscience
Siglecs that Associate with DAP12
Takashi Angata · 2020 · Advances in experimental medicine and biology
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Takako Nakano-Yokomizo, Satoko Tahara‐Hanaoka, Chigusa Nakahashi-Oda, Tsukasa Nabekura, Nadia K. Tchao, Momoko Kadosaki, Naoya Totsuka, Naoki Kurita, Kiyotaka Nakamagoe, Akira Tamaoka et al. · 2011 · The Journal of Experimental Medicine
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Antoni Olona, Subhankar Mukhopadhyay, Charlotte Hateley, Fernando O. Martínez, Siamon Gordon, Jacques V. Behmoaras · 2021 · BMC Biology
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Giuseppina D’Alessandro, Francesco Marrocco, Cristina Limatola · 2022 · Frontiers in Immunology
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Ruth Elliott, Fan Li, Isabelle C. Dragomir, Ming Ming Chua, Brian D. Gregory, Susan Reich Weiss · 2013 · PLoS ONE
Dual functions of microglia in the formation and refinement of neural circuits during development
Hiroyuki Konishi, Hiroshi Kiyama, Masaki Ueno · 2018 · International Journal of Developmental Neuroscience
Neuroinflammatory Pathways in the ALS-FTD Continuum: A Focus on Genetic Variants
Fabiola De Marchi, Giacomo Tondo, Lucia Corrado, Federico Menegon, Davide Aprile, Matteo Anselmi, Sandra D’Alfonso, Cristoforo Comi, Letizia Mazzini · 2023 · Genes
Nasu-Hakola Disease (PLOSL)
Henning Madry, Johannes Prudlo, Aleksandr Grgic, J??rgen Freyschmidt · 2006 · Clinical Orthopaedics and Related Research
Unraveling the genes implicated in Alzheimer's disease
Mohan Giri, Abhilasha Shah, Bibhuti Upreti, Jayanti Chamling Rai · 2017 · Biomedical Reports
Innate immunity to cytomegalovirus: the Cmv1 locus and its role in natural killer cell function
Seung Hwan Lee, John R. Webb, Silvia Marina Vidal · 2002 · Microbes and Infection
EVOO Polyphenols Exert Anti-Inflammatory Effects on the Microglia Cell through TREM2 Signaling Pathway
Manuela Leri, Marzia Vasarri, Federica Carnemolla, Francesco Oriente, Serena Cabaro, Maria Stio, Donatella Degl’Innocenti, Massimo Stefani, Monica Bucciantini · 2023 · Pharmaceuticals
Congenital and Acquired Disorders Presenting as Psychosis in Children and Young Adults
Sheldon Benjamin, Margo D. Lauterbach, Aimee L. Stanislawski-Zygaj · 2013 · Child and Adolescent Psychiatric Clinics of North America
Impaired Fracture Healing Caused by Deficiency of the Immunoreceptor Adaptor Protein DAP12
Masayuki Kamimura, Yu Mori, Akiko Sugahara–Tobinai, Toshiyuki Takai, Eiji Itoi · 2015 · PLoS ONE
SWI and phase imaging reveal intracranial calcifications in the P301L mouse model of human tauopathy
Ni, Ruiqing, Zarb, Yvette, Kuhn, Gisela A., Müller, Ralph, Yundung, Yankey, Nitsch, Roger M., Kulic, Luka, Keller, Annika, Klohs, Jan · 2020 · Magnetic Resonance Materials in Physics, Biology and Medicine
VPatho: a deep learning-based two-stage approach for accurate prediction of gain-of-function and loss-of-function variants
Fang Ge, Chen Li, Shahid Iqbal, Muhammad Arif, Fuyi Li, Maha A. Thafar, Zihao Yan, Apilak Worachartcheewan, Xiaofeng Xu, Jiangning Song et al. · 2022 · Briefings in Bioinformatics
Absence of TREM2 polymorphisms in patients with Alzheimer's disease and Frontotemporal Lobar Degeneration
Chiara Fenoglio, Daniela Galimberti, Laura M. Piccio, Diego Scalabrini, Paola Panina‐Bordignon, Cecilia Buonsanti, Eliana Venturelli, Carlo Lovati, Gianluigi Forloni, Claudio Bruno Mariani et al. · 2006 · Neuroscience Letters
Disease and Region Specificity of Granulin Immunopositivities in Alzheimer Disease and Frontotemporal Lobar Degeneration
Qinwen Mao, Dongyang Wang, Yanqing Li, Missia Kohler, Jayson Wilson, Zachary Parton, Bella Shmaltsuyeva, Demirkan Besim Gursel, Rosa Rademakers, Sandra Weıntraub et al. · 2017 · Journal of Neuropathology & Experimental Neurology
Small nuclear RNA-mediated modulation of splicing reveals a therapeutic strategy for a TREM2 mutation and its post-transcriptional regulation
Motoaki Yanaizu, Kenji Sakai, Youhei Tosaki, Yoshihiro Kino, Jun‐ichi Satoh · 2018 · Scientific Reports
Transcript profiles of dendritic cells of PLOSL patients link demyelinating CNS disorders with abnormalities in pathways of actin bundling and immune response
A. Kiialainen, V. Veckman, J. Saharinen, J. Paloneva, Massimiliano Gentile, P. Hakola, D. Hemelsoet, B. Ridha, O. Kopra, I. Julkunen et al. · 2007 · Journal of molecular medicine
Chromosome 19q13 and multiple sclerosis susceptibility in Finland: a linkage and two-stage association study
Karoliina Reunanen, Saara Finnilä, M Laaksonen, Marja‐Liisa Sumelahti, Juhani Wikstrom, Tomi Pastinen, Satu Kuokkanen, Janna Saarela, Pekka Uimari, Juhani Ruutiainen et al. · 2002 · Journal of Neuroimmunology
Synaptic pruning by microglia: lessons from genetic studies in mice
de Deus, Junia Lara, Faborode, Oluwaseun Samuel, Nandi, Sayan · 2024 · Developmental Neuroscience
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Hye-Won Yang, Danyeong Kim, YoungSoon Yang, Eva Bagyinszky, Seong Soo A. An · 2025 · International Journal of Molecular Sciences
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Shin‐ichi Toyabe, Utako Kaneko, Makoto Uchiyama · 2004 · Journal of Autoimmunity
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Adrienne Anginot, Romain Dacquin, M. Mazzorana, Pierre Jurdic · 2007 · PLoS ONE
Proteomic Analysis of Lymphoblastoid Cells from Nasu-Hakola Patients: A Step Forward in Our Understanding of This Neurodegenerative Disorder
Serena Giuliano, Anna Maria Agresta, Antonella De Palma, Simona Viglio, Pierluigi Mauri, Marco Fumagalli, Paolo Iadarola, Lorenza Montalbetti, Roberta Salvini, Anna Bardoni · 2014 · PLoS ONE
Polycystic Lipomembranous Osteodysplasia with Sclerosing Leukoencephalopathy (PLOSL): A new report of an Italian woman and review of the literature
Veronika Bock, A. Botturi, Paola Gaviani, E. Lamperti, Carmelo Maccagnano, Laura M. Piccio, Antonio Silvani, Andrea Salmaggi · 2013 · Journal of the Neurological Sciences
Trem2/Tyrobp Signaling Protects Against Aortic Dissection and Rupture by Inhibiting Macrophage Activation in Mice
Zenghui Zhang, Maoxiong Wu, Lei Yao, Weibin Zhou, Xiao Liu, Zhiteng Chen, Ping Hua, Lei‐Bo Xu, Lei Lv, Chi-Yu Liu et al. · 2024 · Arteriosclerosis Thrombosis and Vascular Biology
Osteoclast Biology: Regulation of Formation and Function
Yongwon Choi, Roberta Faccio, Steven L. Teitelbaum, Hiroshi Takayanagi · 2015 · Elsevier eBooks
A follow-up study of chromosome 19q13 in multiple sclerosis susceptibility
Alessandro Bonetti, Keijo J. Koivisto, Tuula Pirttilä, Irina Elovaara, Mauri Reunanen, Mikko Laaksonen, Juhani Ruutiainen, Leena Peltonen, Terhi Rantamäki, Pentti J. Tienari · 2009 · Journal of Neuroimmunology
CD11b promotes the differentiation of osteoclasts induced by RANKL through the spleen tyrosine kinase signalling pathway
Guoxi Yang, Xiaoyong Chen, Yan Zhao, Qingsheng Zhu, Chongfei Yang · 2017 · Journal of Cellular and Molecular Medicine
DAP12 impacts trafficking and surface stability of killer immunoglobulin-like receptors on natural killer cells
Tiernan J. Mulrooney, Phillip E. Posch, Carolyn Katovich Hurley · 2013 · Journal of Leukocyte Biology
TREM2 in Neurodegenerative Diseases: Mechanisms and Therapeutic Potential
Ling Li, Xiaoxiao Zheng, Hongyue Ma, Mingxia Zhu, Xiuli Li, Xiaodan Sun, Xinhong Feng · 2025 · Cells
The Differential Diagnosis of Childhood- and Young Adult-Onset Disorders That Include Psychosis
Margo D. Lauterbach, Aimee L. Stanislawski-Zygaj, Sheldon Benjamin · 2008 · Journal of Neuropsychiatry
Function and mechanism of TREM2 in bacterial infection
Zehua Wu, Shiyue Yang, Xiangming Fang, Qiang Shu, Qixing Chen · 2024 · PLoS Pathogens
Blood circulating miR-28-5p and let-7d-5p associate with premature ageing in Down syndrome
Cristina Morsiani, Maria Giulia Bacalini, Salvatore Collura, María Moreno‐Villanueva, Nicolle Breusing, Alexander Bürkle, Tilman Grune, Claudio Franceschi, Magda de Eguileor, Miriam Capri · 2022 · Mechanisms of Ageing and Development
Pattern of DAP12 Expression in Leukocytes from Both Healthy and Systemic Lupus Erythematosus Patients
Nicolas SCHLEINITZ, Laurent Chiche, Sophie Guia, Gaëlle Bouvier, Julie Vernier, Alexis Morice, Elisabeth Houssaint, J.‐R. Harle, Gilles Kaplanski, Félix A. Montero‐Julian et al. · 2009 · PLoS ONE
Phenotypic Expansion in Nasu-Hakola Disease: Immunological Findings in Three Patients and Proposal of a Unifying Pathogenic Hypothesis
Edoardo Errichiello, Efthimios Dardiotis, Fiorenza Mannino, Juha Paloneva, Teresa Mattina, Orsetta Zuffardi · 2019 · Frontiers in Immunology
The Role of Microglia in Inherited White-Matter Disorders and Connections to Frontotemporal Dementia
Daniel W. Sirkis, Luke W. Bonham, Jennifer S. Yokoyama · 2021 · The Application of Clinical Genetics
Role of Microglia in Central Nervous System Development and Plasticity
Dorothy P. Schafer, Beth Stevens, Mariko L. Bennett, F. Chris Bennett · 2024 · Cold Spring Harbor Perspectives in Biology
Primary Microglia Dysfunction or Microgliopathy: A Cause of Dementias and Other Neurological or Psychiatric Disorders
Marino Muxfeldt Bianchin, Zhezu Snow · 2022 · Neuroscience
Understanding Microglia–Neuron Cross Talk: Relevance of the Microglia–Neuron Cocultures
Fernando Correa, Míriam Hernangómez, Carmen Guaza · 2013 · Methods in molecular biology
Computational analysis of human disease-associated genes and their protein products
K Sreekumar · 2001 · Current Opinion in Genetics & Development
Poly-γ-glutamic acid suppresses osteoclastogenesis in human osteoclast precursors and prevents joint damage in a collagen-induced murine arthritis model
Bitnara Lee, Sungsin Jo, Sung-Min Kim, Mi‐La Cho, Sung‐Hwan Park, Jeehee Youn, Jong Dae Ji, Tae‐Hwan Kim · 2018 · Immunology Letters
Role of triggering receptor expressed on myeloid cells 2 (TREM2) in neurodegenerative dementias
Sadat Shafi, Archu Singh, Abdallah Mohammad Ibrahim, Noora Alhajri, Tareq Abu Izneid, Faheem Hyder Pottoo · 2021 · European Journal of Neuroscience
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Yanxia Liu, Sandra Theil, Melanie Ibach, Jochen Walter · 2024 · Cellular and Molecular Life Sciences