Clearance of amyloid β-peptide from brain: transport or metabolism?

Zlokovic, Berislav V., Yamada, Shinya, Holtzman, David, Ghiso, Jorge, Frangione, Blas·2000·Nature Medicine

DOI 10.1038/77397

Cited by (188)

Items 101–188 of 188

Age-Related Decline in Brain and Hepatic Clearance of Amyloid-Beta is Rectified by the Cholinesterase Inhibitors Donepezil and Rivastigmine in Rats
Mohamed, Loqman A., Qosa, Hisham, Kaddoumi, Amal · 2015 · ACS Chemical Neuroscience
Interleukin-4 affects microglial autophagic flux
Run-Hong Tang, Rui-Qun Qi, Hua-Yan Liu · 2019 · Neural Regeneration Research
Method for measurement of the blood–brain barrier permeability in the perfused mouse brain: application to amyloid-β peptide in wild type and Alzheimer’s Tg2576 mice
Barbra LaRue, Elizabeth Hogg, Abhay P. Sagare, Suzana S. Jovanovic, Lawrence M. Maness, Calvin R. Maurer, Rashid Deane, Berislav V. Zloković · 2004 · Journal of Neuroscience Methods
HIV-1-induced amyloid beta accumulation in brain endothelial cells is attenuated by simvastatin
Ibolya Edit Andras, Sung Yong Eum, Wen Huang, Yu Zhong, Bernhard Hennig, Michal J. Toborek · 2009 · Molecular and Cellular Neuroscience
Monocytes and Alzheimer’s disease
Yu Feng, Lei Li, Xiaohong Sun · 2011 · Neuroscience Bulletin
Quercetin protects against the Aβ25–35-induced amnesic injury: Involvement of inactivation of RAGE-mediated pathway and conservation of the NVU
Rui Liu, Tiantai Zhang, Dan Zhou, Xiaoyu Bai, Weiling Zhou, Chao Huang, Jun-ke Song, Fang-rui Meng, Caixia Wu, Lin Li et al. · 2012 · Neuropharmacology
Alzheimer’s Disease: An Overview of Major Hypotheses and Therapeutic Options in Nanotechnology
Mugdha Agarwal, Rizwan Alam, Mohd Kabir Haider, Md. Zubbair Malik, Dae-Kwang Kim · 2020 · Nanomaterials
Docosahexaenoic Acid Reduces Amyloid-β Induced Toxicity in Cells of the Neurovascular Unit
Szilvia Veszelka, Andrea E. Tóth, Fruzsina R. Walter, Zsolt Datki, Emese Mózes, Lívia Fülöp, Zsolt Bozsó, Éva Hellinger, Mónika Vastag, Barbara Orsolits et al. · 2013 · Journal of Alzheimer s Disease
Is Beta-Amyloid Accumulation a Cause or Consequence of Alzheimer's Disease?
Shaoxun Wang, Paige N Mims, Richard J. Roman, Fan Fan · 2016 · PubMed
Metabolism of amyloid β peptide and pathogenesis of Alzheimer’s disease
Takaomi C. Saido · 2013 · Proceedings of the Japan Academy Series B
Targeting ApoE4/ApoE receptor LRP1 in Alzheimer's disease
Henna Martiskainen, Annakaisa Haapasalo, Kaisa M. A. Kurkinen, Jussi Pihlajamäki, Hilkka S. Soininen, Mikko O. Hiltunen · 2013 · Expert Opinion on Therapeutic Targets
The multi-faceted impact of methamphetamine on Alzheimer’s disease: From a triggering role to a possible therapeutic use
Mayuri Shukla, Bruno Vincent · 2020 · Ageing Research Reviews
Reference tissue normalization in longitudinal 18F-florbetapir positron emission tomography of late mild cognitive impairment
Sepideh Shokouhi, John W. Mckay, Suzanne L. Baker, Hakmook Kang, Aaron B. Brill, Harry E. Gwirtsman, William R. Riddle, Daniel O. Claassen, Baxter P. Rogers, Alzheimer’s Disease Neuroimaging Initiative · 2016 · Alzheimer s Research & Therapy
Common Pesticide, Dichlorodiphenyltrichloroethane (DDT), Increases Amyloid-β Levels by Impairing the Function of ABCA1 and IDE: Implication for Alzheimer’s Disease
Li, Gongbo, Kim, Chaeyoung, Kim, Jaekwang, Yoon, Hyejin, Zhou, Huadong, Kim, Jungsu · 2015 · Journal of Alzheimer's Disease
Ectodomain shedding of the receptor for advanced glycation end products: a novel therapeutic target for Alzheimer’s disease
Ling Zhang, R. Postina, Ying-Qun Wang · 2009 · Cellular and Molecular Life Sciences
Recent Insights on Alzheimer’s Disease Originating from Yeast Models
David Seynnaeve, Mara Del Vecchio, Gernot Fruhmann, Joke Verelst, Melody Cools, Jimmy Beckers, Daniel P. Mulvihill, Joris Winderickx, Vanessa Franssens · 2018 · International Journal of Molecular Sciences
Sevoflurane alters the expression of receptors and enzymes involved in Aβ clearance in rats
Y. Liu, M. Gao, Lang-Chuan Ma, Ling Zhang, N. Pan · 2013 · Acta Anaesthesiologica Scandinavica
Beta-amyloid deposition in the brains of rats chronically infused with thiorphan or lipopolysaccharide: the role of ascorbic acid in the vehicle
Beatrice Hauss‐Wegrzyniak, Gary L. Wenk · 2002 · Neuroscience Letters
Regulation of cholesterol efflux by amyloid β secretion
Gillian A. Scullion, Jill H. Fowler, K. Karali, Robin Coltman, Ryan Green, Colin Smith, Karen Horsburgh · 2010 · Journal of Neuroscience Research
Impairments in Brain-to-Blood Transport of Amyloid-β and Reabsorption of Cerebrospinal Fluid in an Animal Model of Alzheimer's Disease are Reversed by Antisense Directed Against Amyloid-β Protein Precursor
W. Banks, V. B. Kumar, S. Farr, R. Nakaoke, S. Robinson, J. Morley · 2011 · Journal of Alzheimer's Disease
Mitochondrial mechanisms in amyloid beta peptide-induced cerebrovascular degeneration
Ming‐Jen Hsu, Joen‐Rong Sheu, Chien‐Huang Lin, Ming‐Yi Shen, Chung Y. Hsu · 2009 · Biochimica et Biophysica Acta (BBA) - General Subjects
Relationships between the amyloid precursor protein and its various proteolytic fragments and neuronal systems
Sally Hunter, Carol Brayne · 2012 · Alzheimer s Research & Therapy
Decrease in HDL-C is Associated with Age and Household Income in Adults from the Korean National Health and Nutrition Examination Survey 2017: Correlation Analysis of Low HDL-C and Poverty
Kyung‐Hyun Cho, Hye‐Jeong Park, Suk‐Jeong Kim, Jae-Ryong Kim · 2019 · International Journal of Environmental Research and Public Health
Secretory proteostasis of the retinal pigmented epithelium: Impairment links to age-related macular degeneration
Luminita Paraoan, Umar Sharif, Emil Carlsson, Wasu Supharattanasitthi, Nur Musfirah Mahmud, Tengku Ain Kamalden, Paul Stephenson Hiscott, Malcolm Joseph Jackson, Ian Grierson · 2020 · Progress in Retinal and Eye Research
Cerebrospinal fluid dynamics
2021 · Croatian Medical Journal
Biomarkers Related to Endothelial Dysfunction and Vascular Cognitive Impairment: A Systematic Review
Rui Martins, Maria Clara Zanon Zotin, Guilherme Riccioppo Rodrigues, Octávio Marques Pontes‐Neto · 2020 · Dementia and Geriatric Cognitive Disorders
Impaired Orthotopic Glioma Growth and Vascularization in Transgenic Mouse Models of Alzheimer's Disease
Paris, Daniel, Ganey, Nowel, Banasiak, Magdalena, Laporte, Vincent, Patel, Nikunj, Mullan, Myles, Murphy, Susan F., Yee, Gi-Taek, Bachmeier, Corbin, Ganey, Christopher et al. · 2010 · The Journal of Neuroscience
Progressive neurovascular disturbances in the cerebral cortex of Alzheimer's disease-model mice: protection by atorvastatin and pitavastatin
Tomoko Kurata, Kazunori Miyazaki, Miki Kozuki, Nobutoshi Morimoto, Yasuyuki Ohta, Yoshio Ikeda, Koji Abe · 2011 · Neuroscience
Protection of the Blood-Brain Barrier by Pentosan Against Amyloid-β-Induced Toxicity
Mária A. Deli, Szilvia Veszelka, Boglárka Csiszár, Andrea E. Tóth, Ágnes Kittel, Mária Csete, Áron Sipos, Anikó Szalai, Lívia Fülöp, Botond Penke et al. · 2010 · Journal of Alzheimer s Disease
In Vitro Investigation of Amyloid-β Hepatobiliary Disposition in Sandwich-Cultured Primary Rat Hepatocytes
Loqman A. Mohamed, Amal Kaddoumi · 2013 · Drug Metabolism and Disposition
Amyloid-beta accumulation, neurogenesis, behavior, and the age of rats.
Russell M. Church, Miles C. Miller, David M. Freestone, Catharine Chiu, Doreen P. Osgood, Jason T. Machan, Arthur A. Messier, Conrad E. Johanson, Gerald D. Silverberg · 2014 · Behavioral Neuroscience
Amyloid Beta Hypothesis in Alzheimer's Disease: Major Culprits and Recent Therapeutic Strategies
Kalarickal Vijayan Dileep, Remya Chandra · 2019 · Current Drug Targets
Kaolin-induced chronic hydrocephalus accelerates amyloid deposition and vascular disease in transgenic rats expressing high levels of human APP
Gerald D. Silverberg, Miles C. Miller, Crissey L. Pascale, Ilias N Caralopoulos, Yüksel Ağca, Cansu Agca, Edward G. Stopa · 2015 · Fluids and Barriers of the CNS
Effects of a behaviorally active antibody on the brain uptake and clearance of amyloid beta proteins
William A. Banks, Patrizia Pagliari, Ryota Nakaoke, John Edward Morley · 2004 · Peptides
Studying the Neurovascular Unit: An Improved Blood–Brain Barrier Model
Christoph M. Zehendner, Heiko J. Luhmann, Christoph R.W. Kuhlmann · 2009 · Journal of Cerebral Blood Flow & Metabolism
Selection of peptides binding to the amyloid b-protein reveals potential inhibitors of amyloid formation
A. L. Schwarzman, Maria V. Tsiper, Luisa L. Gregori, Dmitry Goldgaber, Janusz Frackowiak, Bozena Mazur‐Kolecka, Anastasia E. Taraskina, С. Н. Пчелина, Michael Peter Vitek · 2005 · Amyloid
Cerebrovascular alterations in NAFLD: Is it increasing our risk of Alzheimer's disease?
Anna Hadjihambi · 2021 · Analytical Biochemistry
The ability of neuropeptide Y to mediate responses in the murine cutaneous microvasculature: an analysis of the contribution of Y1 and Y2 receptors
Duc Quyen Chu, Helen M. Cox, Soraia K.P. Costa, Herbert Herzog, Susan Diana Brain · 2003 · British Journal of Pharmacology
Altered dynamics of glymphatic flow in a mature-onset Tet-off APP mouse model of amyloidosis
Inès R. H. Ben-Nejma, A Keliris, Verdi Vanreusel, Peter Ponsaerts, Annemie Van der Linden, Georgios A. Keliris · 2023 · Alzheimer s Research & Therapy
Angiotensin II type 1 receptor deficiency protects against the impairment of blood–brain barrier in a mouse model of traumatic brain injury
Lijun Yang, Zeshang Chen, Xiangdong Wan, Minghao Liu, Jianliang Wu, Yan Chen, Gengshen Zhang, Zhenzeng Fan · 2021 · International Journal of Neuroscience
Single Photon Emission Computed Tomography and Positron Emission Tomography Imaging of Multi-drug Resistant P-glycoprotein—Monitoring a Transport Activity Important in Cancer, Blood–Brain Barrier Function and Alzheimer's Disease
David R Piwnica-Worms, Aparna Hemant Kesarwala, Andrea Pichler, Julie L. Prior, Vijay Sharma · 2006 · Neuroimaging Clinics of North America
Analysis of Cerebral Small Vessel Changes in AD Model Mice
Abu Zaffar Shibly, Abdullah Md. Sheikh, Makoto Michikawa, Shatera Tabassum, Abul Kalam Azad, Xiaojing Zhou, Yuchi Zhang, Shozo Yano, Atsushi Nagai · 2022 · Biomedicines
Endogenous Secretory Receptor for Advanced Glycation End-Products Inhibits Amyloid-β1-42 Uptake into Mouse Brain
Takahiro Sugihara, Seiichi Munesue, Yasuhiko Yamamoto, Shigeru Sakurai, Nasima Akhter, Yoji Kitamura, Kazuhiro Shiba, Takuo Watanabe, Hideto Yonekura, Yasuhiko Hayashi et al. · 2012 · Journal of Alzheimer s Disease
Cholesterol and 24S-hydroxycholesterol trafficking in Alzheimer’s disease
Walter J. Lukiw · 2006 · Expert Review of Neurotherapeutics
Dysfunctional Characteristics of Circulating Angiogenic Cells in Alzheimer's Disease
Soon‐Tae Lee, Kon Chu, Keun‐Hwa Jung, Daejong Jeon, Jae‐Jun Bahn, Jinhee Kim, Sang Kun Lee, Manho Kim, Jae‐Kyu Roh · 2010 · Journal of Alzheimer s Disease
Effect of mouse strain as a background for Alzheimer’s disease models on the clearance of amyloid-β
Hisham Qosa, Amal Kaddoumi · 2016 · Journal of Systems and Integrative Neuroscience
6-Phenoxy-2-phenylbenzoxazoles, novel inhibitors of receptor for advanced glycation end products (RAGE)
Kwang‐Hyun Choi, Kwang Su Lim, Juhee Shin, Seo Hee Kim, Young‐Ger Suh, Hyun‐Seok Hong, Hee Yeon Kim, Hee-Jin Ha, Young-Ho Kim, Jiyoun Lee et al. · 2015 · Bioorganic & Medicinal Chemistry
Perinatal Tissue-Derived Stem Cells: An Emerging Therapeutic Strategy for Challenging Neurodegenerative Diseases
Annalisa Bruno, Cristina Milillo, Federico Anaclerio, Carlotta Buccolini, Anastasia Dell’Elice, Ilaria Angilletta, Marco Gatta, Patrizia Ballerini, Ivana Antonucci · 2024 · International Journal of Molecular Sciences
Role of A β Transport and Clearance in the Pathogenesis and Treatment of Alzheimer’s Disease
David M. Holtzman, Berislav V. Zloković · 2007 · Springer eBooks
Overview of Preclinical and Clinical Trials of Nanoparticles for the Treatment of Brain Metastases
Muhammad Izhar, Mohamed Fathi Al Gharyani, Ahed H. Kattaa, Juan J. Cardona, Ruchit P. Jain, Elaheh Shaghaghian, Yusuke S. Hori, Fred C. Lam, Deya Abu-Reesh, Sara Coleman Emrich et al. · 2025 · Pharmaceutics
Physical Exercise May Increase Plasma Concentration of High-Density Lipoprotein-Cholesterol in Patients With Alzheimer’s Disease
Camilla Steen Jensen, Christian Sandøe Musaeus, Ruth Frikke‐Schmidt, Birgitte Bo Andersen, Nina Beyer, Hanne Gottrup, Peter Høgh, Karsten Vestergaard, Lene Wermuth, Kristian Steen Frederiksen et al. · 2020 · Frontiers in Neuroscience
Reduced estimated glomerular filtration rate in Alzheimer's disease
Enda Kerr, David Craig, Bernadette McGuinness, Kevin Dynan, Damian G. Fogarty, Janet A. Johnston, Anthony Peter Passmore · 2009 · International Journal of Geriatric Psychiatry
Extracellular Chaperones and Amyloids
Mark R. Wilson, Justin J. Yerbury, Stephen Poon · 2008 · Springer eBooks
Serum-Derived Immunoglobulins Neutralize Adverse Effects of Amyloid-β Peptide on the Integrity of a Blood-Brain Barrier In Vitro Model
Verena Poetsch, Winfried Neuhaus, Christian R. Noe · 2010 · Journal of Alzheimer s Disease
Understanding monocyte-driven neuroinflammation in Alzheimer’s disease using human cortical organoid microphysiological systems
Tian, Chunhui, Ao, Zheng, Cerneckis, Jonas, Cai, Hongwei, Chen, Lei, Niu, Hengyao, Takayama, Kazuo, Kim, Jungsu, Shi, Yanhong, Gu, Mingxia et al. · 2025 · Science Advances
Sensory gamma entrainment: Impact on amyloid protein and therapeutic mechanism
Jiaying Hu, Leyan Zheng, Ziyu Guan, Kexin Zhong, Fankai Huang, Qiankai Huang, Jing Yang, Weiyun Li, Shanshan Li · 2023 · Brain Research Bulletin
Modeling Effect of a γ-Secretase Inhibitor on Amyloid-β Dynamics Reveals Significant Role of an Amyloid Clearance Mechanism
Raibatak Das, Robert B. Nachbar, Leah Edelstein-keshet A, Jeffrey S. Saltzman, Matthew C. Wiener, Ansuman Bagchi, James A. Bailey, Daniel Coombs, Adam J. Simon, Richard J Hargreaves et al. · 2010 · Bulletin of Mathematical Biology
Targeted Chemotherapy in Drug-Resistant Tumors, Noninvasive Imaging of P-Glycoprotein-Mediated Functional Transport in Cancer, and Emerging Role of Pgp in Neurodegenerative Diseases
Jothilingam Sivapackiam, Seth T. Gammon, Scott E. Harpstrite, Vijay Sharma · 2009 · Methods in molecular biology
Impact of age, hypercholesterolemia, and the vitamin D receptor on brain endogenous β‐amyloid peptide accumulation in mice
Hao Peng, Paola Bukuroshi, Matthew R. Durk, Paul V. Grootendorst, Xiaoyu Yan, Sophie R. Pan, Inés A.M. de Lannoy, K. Sandy Pang · 2021 · Biopharmaceutics & Drug Disposition
Human Amyloid-β40 Kinetics after Intravenous and Intracerebroventricular Injections and Calcitriol Treatment in Rats In Vivo
H. B. Peng, K. Noh, Sophie R. Pan, V. Saldivia, Sylvia Serson, Anja Toscan, I. D. de Lannoy, K. Pang · 2020 · Drug Metabolism And Disposition
Uncovering the System Vulnerability and Criticality of Human Brain Under Dynamical Neuropathological Events in Alzheimer’s Disease
Jingwen Zhang, Qing Liu, Haorui Zhang, Michelle Dai, Qianqian Song, Defu Yang, Guorong Wu A, Minghan Chen · 2023 · Journal of Alzheimer s Disease
Traumatic brain injury and neurodegenerative diseases: the role of axonal injury and amyloid-β
Dexi Bi, Boying Gao, Yanan Shen, Zhibo Dai, Shichun Yang, Ligang Wang · 2025 · Brain Research
A mathematical model on Aβ blood–brain transport: Simulations of plaques’ formation in Alzheimer’s disease
Eleonora Ficiarà, Ilaria Stura, Caterina Guiot, Ezio Venturino · 2023 · Medical Hypotheses
Modulating Role of TTR in Aβ Toxicity, from Health to Disease
Isabel Cardoso, Luís Miguel Santos, Mobina Alemi · 2016 · InTech eBooks
Measuring Amyloid‐β Peptide Concentrations in Murine Brain with Improved ELISA Assay
Hao Peng, Inés A.M. de Lannoy, K. Sandy Pang · 2021 · Current Protocols
Differences in the amyloid-β-induced inflammatory response in microglia from C57BL/6 and A/J strains of mice
Sherri Dudal, Céline Morissette, Diane Lacombe, Patrick Tremblay, Francine Gervais · 2004 · Journal of Neuroimmunology
Integrating Data for Modeling Biological Complexity
Sally Hunter, Carol Brayne · 2013 · Springer eBooks
Disease Influence on BBB Transport in Neurodegenerative Disorders
Elizabeth C. M. de Lange · 2013 · AAPS advances in the pharmaceutical sciences series
Apolipoproteins in Different Amyloidoses
Marcin Sadowski, Thomas Wısnıewskı · 2007 · Springer eBooks
Understanding monocyte-driven neuroinflammation in Alzheimer’s disease using human brain organoid microphysiological systems
Chunhui Tian, Zheng Ao, Jonas Cerneckis, Hongwei Cai, Lei Chen, Henyao Niu, Kazuo Takayama, Jungsu Kim, Yanhong Shi, Mingxia Gu et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
Visualization of Cerebrospinal Fluid Dynamics in Normal and Spinal Pathophysiological Conditions Using Time Spatial Spin Labeling Inversion Pulse-MRI
Shinya Yamada · 2017 · Spinal Surgery
Cerebral Amyloid Deposition With 18F ‐Florbetapir PET Mediates Retinal Vascular Density and Cognitive Impairment in Alzheimer's Disease
Zhigeng Chen, Hai‐Long He, Zhongyuan Qi, Sheng Bi, Hongwei Yang, Xuanyu Chen, Tianze Xu, Zi‐Bing Jin, Shaozhen Yan, Jie Lu · 2025 · Human Brain Mapping
Co-Morbid Disease as Risk Factors Associated with Alzheimer’s Disease- An Overview
Anubhav Tyagi, Nikhila Shekhar, Sakshi Tyagi · 2025 · Current Behavioral Neuroscience Reports
Primary cilia–extracellular vesicle crosstalk in Alzheimer's disease: Emerging mechanisms and biomarker potential
Vishal Singh Guleria, Charisse N. Winston · 2026 · Alzheimer s & Dementia
Leptin, Insulin and Blood-Brain Barrier Relations in Obesity
W. Banks, N. Nonaka, S. Shioda, R. Nakaoke, J. Morley · 2005 · Elsevier eBooks
Cholesterol, β-amyloid, and Alzheimer's disease
Miguel A. Pappolla, Suzana S. Petanceska, Lawrence M. Refolo, Nicolas Guillermo Bazan · 2003 · Advances in cell aging and gerontology
A Conclusive Review on Amyloid Beta Peptide Induced Cerebrovascular Degeneration and the Mechanism in Mitochondria
Jayalal L.P. Merlin · 2013 · Journal of the Chosun Natural Science
Implications of Human Umbilical Cord Blood Cells: An Immunotherapeutic Strategy for Alzheimer's Disease
Donna Darlington · 2014 · Digital Commons - University of South Florida (University of South Florida)
Diseases Mediated by the BBB
William A. Banks · 2013 · Elsevier eBooks
The role of NPxY domains in LRP1 receptor maturation and function
Thorsten Pflanzner · 2011 · Gutenberg Open Science
Diseases Mediated by the BBB: From Alzheimer's to Obesity
William A. Banks · 2006 · Elsevier eBooks
Dynamics of brain-fluid circulation are altered in the mature-onset Tet-off APP mouse model of amyloidosis
Inès R. H. Ben-Nejma, A Keliris, Verdi Vanreusel, Peter Ponsaerts, Annemie Van der Linden, Georgios A. Keliris · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
Disease Influence on BBB Transport in Neurodegeneration
Elizabeth C. M. de Lange · 2022 · AAPS advances in the pharmaceutical sciences series
Additional file 2 of Microglia prevent beta-amyloid plaque formation in the early stage of an Alzheimer’s disease mouse model with suppression of glymphatic clearance
Weixi Feng, Yanli Zhang, Ze Wang, Hanrong Xu, Ting Wu, Charles Marshall, Junying Gao, Ming Xiao · 2020 · Figshare
Additional file 1 of Microglia prevent beta-amyloid plaque formation in the early stage of an Alzheimer’s disease mouse model with suppression of glymphatic clearance
Feng, Weixi, Zhang, Yanli, Ze Wang, Xu, Hanrong, Wu, Ting, Charles Marshall, Gao, Junying, Xiao, Ming · 2020 · Figshare
Additional file 1 of Altered dynamics of glymphatic flow in a mature-onset Tet-off APP mouse model of amyloidosis
Inès R. H. Ben-Nejma, A Keliris, Verdi Vanreusel, Peter Ponsaerts, Annemie Van der Linden, Georgios A. Keliris · 2023 · Figshare
Rôle de la neuroinflammation et du récepteur microglial TREM2 dans la progression de deux modèles de tauopathie
Audrey Vautheny · 2019 · theses.fr (ABES)
Modeling the control on the formation and dissolution of amyloid plaques in Alzheimer’s disease
Francesca Acotto, Iulia Martina Bulai, Francesca Gladiali · 2026 · Communications in Nonlinear Science and Numerical Simulation