Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
Bard, Frédérique, Cannon, Catherine, Barbour, Robin, Burke, Rae-Lyn, Games, Dora, Grajeda, Henry, Guido, Teresa, Hu, Kang +15 more·2000·Nature Medicine
DOI 10.1038/78682
Cited by (1,003)
Items 701–800 of 1,003
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- Neuroinflammation in Alzheimer's disease: protector or promoter?Norbert Žilka, M Ferencĭk, I Hulín · 2006 · Bratislavské lekárske listy/Bratislava medical journal
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- Neuroinflammation and tumor necrosis factor signaling in the pathophysiology of Alzheimer’s diseaseMalú G. Tansey, McAlpine · 2008 · Journal of Inflammation Research
- Dendrimeric Aβ1–15 is an effective immunogen in wildtype and APP-tg miceTimothy J. Seabrook, Katelyn Thomas, Liying Jiang, Jeanne K. Bloom, Edward Spooner, Marcel Maier, Gal Bitan, Cynthia Ann Lemere · 2006 · Neurobiology of Aging
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- Do age-associated changes in ‘physiologic’ autoantibodies contribute to infection, atherosclerosis, and Alzheimer's disease?Marc E. Weksler, Michèle Goodhardt · 2002 · Experimental Gerontology
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- Reversal of amyloid β toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid β antibodyNeelima B. Chauhan, George J. Siegel · 2002 · Journal of Neuroscience Research
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- Importance of GPCR-Mediated Microglial Activation in Alzheimer’s DiseaseMd. Ezazul Haque, In‐Su Kim, Md. Jakaria, Mahbuba Akther, Dong‐Kug Choi · 2018 · Frontiers in Cellular Neuroscience
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