Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

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1. Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms
   Sastre, Magdalena, Klockgether, Thomas, Heneka, Michael T. · 2006 · International Journal of Developmental Neuroscience
2. NEURODEGENERATIVE DISEASES: New Concepts of Pathogenesis and Their Therapeutic Implications
   Daniel Skovronsky, Virginia M.‐Y. Lee, John Q. Trojanowski · 2006 · Annual Review of Pathology Mechanisms of Disease
3. Reversible memory loss in a mouse transgenic model of Alzheimer’s disease
   Kotilinek, Linda A., Bacskai, Brian, Westerman, Marcus, Kawarabayashi, Takeshi, Younkin, Linda, Hyman, Bradley T., Younkin, Steven, Ashe, Karen H. · 2002 · The Journal of Neuroscience
4. Targeting protein aggregation for the treatment of degenerative diseases
   Yvonne S. Eisele, Cecília Monteiro, Colleen Fearns, Sandra E. Encalada, R. Luke Wiseman, Evan T. Powers, Jeffery W. Kelly · 2015 · Nature Reviews Drug Discovery
5. Therapeutically effective antibodies against amyloid-β peptide target amyloid-β residues 4–10 and inhibit cytotoxicity and fibrillogenesis
   JoAnne McLaurin, Roxana Cecal, Meredith E. Kierstead, X. Tian, Amie L. Phinney, Marilena Manea, J.E. French, Mark H. L. Lambermon, Audrey A. Darabie, M.E. Brown et al. · 2002 · Nature Medicine
6. Epitope and isotype specificities of antibodies to β-amyloid peptide for protection against Alzheimer's disease-like neuropathology
   Bard, Frédérique, Barbour, Robin, Cannon, Catherine, Carretto, Robert, Fox, Michael, Games, Dora, Guido, Teresa, Hoenow, Kathleen, Hu, Kang, Johnson-Wood, Kelly et al. · 2003 · Proceedings of the National Academy of Sciences
7. The benefits and limitations of animal models for translational research in neurodegenerative diseases
   Jucker, Mathias · 2010 · Nature Medicine
8. Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage.
   Donna M. Wilcock, Amyn M. Rojiani, Arnon Rosenthal, Sangeetha Subbarao, Melissa J. Freeman, Marcia N. Gordon, David Morgan · 2004 · Journal of Neuroinflammation
9. Microglial Beclin 1 Regulates Retromer Trafficking and Phagocytosis and Is Impaired in Alzheimer’s Disease
   Lucin, Kurt M., O’Brien, Caitlin E., Bieri, Gregor, Czirr, Eva, Mosher, Kira I., Abbey, Rachelle J., Mastroeni, Diego F., Rogers, Joseph, Spencer, Brian, Masliah, Eliezer et al. · 2013 · Neuron
10. Alzheimer Disease: Mechanistic Understanding Predicts Novel Therapies
    Dennis J. Selkoe · 2004 · Annals of Internal Medicine
11. Microglia and inflammatory mechanisms in the clearance of amyloid β peptide
    Rogers, Joseph, Strohmeyer, Ron, Kovelowski, C.J., Li, Rena · 2002 · Glia
12. Antibodies Targeted to the Brain with Image-Guided Focused Ultrasound Reduces Amyloid-β Plaque Load in the TgCRND8 Mouse Model of Alzheimer's Disease
    Jessica F. Jordão, Carlos A. Ayala‐Grosso, Kelly A. Markham, Yuexi Huang, Rajiv Chopra, JoAnne McLaurin, Kullervo Hynynen, Isabelle Aubert · 2010 · PLoS ONE
13. How chronic inflammation can affect the brain and support the development of Alzheimer's disease in old age: the role of microglia and astrocytes
    Blasko, Imrich, Stampfer‐Kountchev, Michaela, Robatscher, Peter, Veerhuis, Robert, Eikelenboom, Piet, Grubeck‐Loebenstein, Beatrix · 2004 · Aging Cell
14. Tau Aggregation and Its Interplay with Amyloid-β
    Nisbet, Rebecca M., Polanco, Juan-Carlos, Ittner, Lars M., Götz, Jürgen · 2015 · Acta Neuropathologica
15. Alzheimer's Disease
    Dennis J. Selkoe · 2011 · Cold Spring Harbor Perspectives in Biology
16. A -related angiitis: primary angiitis of the central nervous system associated with cerebral amyloid angiopathy
    Scolding, N. J. · 2005 · Brain
17. Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease
    Gouras, Gunnar K., Tampellini, Davide, Takahashi, Reisuke H., Capetillo-Zarate, Estibaliz · 2010 · Acta Neuropathologica
18. Il10 Deficiency Rebalances Innate Immunity to Mitigate Alzheimer-Like Pathology
    Guillot-Sestier, Marie-Victoire, Doty, Kevin R., Gate, David, Rodriguez, Javier, Leung, Brian P., Rezai-Zadeh, Kavon, Town, Terrence · 2015 · Neuron
19. Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-β
    Joseph W. Arndt, Fang Qian, Benjamin A. Smith, Chao Quan, Krishna Praneeth Kilambi, Martin W. Bush, Thomas Walz, R. Blake Pepinsky, Thierry Bussière, Stefan Hamann et al. · 2018 · Scientific Reports
20. Nitrated α–Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons
    Eric J. Benner, Rebecca Banerjee, Ashley D. Reynolds, Simon Sherman, В. М. Писарев, Vladislav Tsiperson, Craig Nemachek, Pawel S. Ciborowski, Serge Przedborski, Rodney Lee Mosley et al. · 2008 · PLoS ONE
21. Therapeutic approaches to Alzheimer's disease
    Hans‐Wolfgang Klafki, Matthias Staufenbiel, Johannes Kornhuber, Jens Wiltfang · 2006 · Brain
22. Scavenger receptors in neurobiology and neuropathology: Their role on microglia and other cells of the nervous system
    Jens Husemann, John D. Loike, Roman Anankov, Maria Febbraio, Samuel C. Silverstein · 2002 · Glia
23. Cerebrospinal Fluid Tau and β-Amyloid: How Well Do These Biomarkers Reflect Autopsy-Confirmed Dementia Diagnoses?
    Clark, Christopher M., Xie, Sharon, Chittams, Jesse, Ewbank, Douglas, Peskind, Elaine, Galasko, Douglas, Morris, John C., McKeel, Daniel W., Farlow, Martin, Weitlauf, Sharon L. et al. · 2003 · Archives of Neurology
24. Evaluation of the safety and immunogenicity of synthetic Aβ42 (AN1792) in patients with AD
    Bayer, A. J., Bullock, R., Jones, R. W., Wilkinson, D., Paterson, K. R., Jenkins, L., Millais, S. B., Donoghue, S. · 2005 · Neurology
25. Clinical practice with anti-dementia drugs: A revised (third) consensus statement from the British Association for Psychopharmacology
    John Tiernan O'Brien, Clive Holmes, Matthew S. Jones, Roy W. Jones, Gill Livingston, Ian Grant McKeith, Peter J. Mittler, Peter Passmore, Craig William Ritchie, Louise A. Robinson et al. · 2017 · Journal of Psychopharmacology
26. Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition
    Colombo, Alessio Vittorio, Sadler, Rebecca Katie, Llovera, Gemma, Singh, Vikramjeet, Roth, Stefan, Heindl, Steffanie, Sebastian Monasor, Laura, Verhoeven, Aswin, Peters, Finn, Parhizkar, Samira et al. · 2021 · eLife
27. Naturally occurring phytochemicals for the prevention of Alzheimer’s disease
    Jiyoung Kim, Hyong Joo Lee, Ki Won Lee · 2009 · Journal of Neurochemistry
28. Can Alzheimer disease be prevented by amyloid-β immunotherapy?
    Lemere, Cynthia A., Masliah, Eliezer · 2010 · Nature Reviews Neurology
29. Immune Signaling in Neurodegeneration
    Hammond, Timothy R., Marsh, Samuel E., Stevens, Beth · 2019 · Immunity
30. Passive Immunization with Anti-Tau Antibodies in Two Transgenic Models
    Xiyun Chai, Su Wu, Tracey K. Murray, Robert D. Kinley, Claire V. Cella, Helen Sims, Nicola Buckner, Jenna M. Hanmer, Peter Davies, Michael J. O’Neill et al. · 2011 · Journal of Biological Chemistry
31. Vaccination with soluble Aβ oligomers generates toxicity‐neutralizing antibodies
    Lambert, Mary P., Viola, Kirsten L., Chromy, Brett A., Chang, Lei, Morgan, Todd E., Yu, Jiaxin, Venton, Duane L., Krafft, Grant A., Finch, Caleb E., Klein, William L. · 2001 · Journal of Neurochemistry
32. Microglia Function in Alzheimer’s Disease
    Egle Solito, Magdalena Sastre · 2012 · Frontiers in Pharmacology
33. LPS receptor (CD14): a receptor for phagocytosis of Alzheimer's amyloid peptide
    Yang Liu, Silke Walter, Massimiliano Stagi, Dmitry Cherny, Maryse Letièmbre, Walter Schulz‐Schaeffer, Holger Heine, Botond Penke, Harald Neumann, Klaus C Fassbender · 2005 · Brain
34. Microglia receptors and their implications in the response to amyloid β for Alzheimer’s disease pathogenesis
    Doens, Deborah, Fernández, Patricia L · 2014 · Journal of Neuroinflammation
35. Massive gliosis induced by interleukin‐6 suppresses Aβ deposition <i>in vivo:</i> evidence against inflammation as a driving force for amyloid deposition
    Chakrabarty, Paramita, Jansen‐West, Karen, Beccard, Amanda, Ceballos‐Diaz, Carolina, Levites, Yona, Verbeeck, Christophe, Zubair, Abba C., Dickson, Dennis, Golde, Todd E., Das, Pritam · 2010 · The FASEB Journal
36. Amyloid-β plaque reduction, endogenous antibody delivery and glial activation by brain-targeted, transcranial focused ultrasound
    Jordão, Jessica F., Thévenot, Emmanuel, Markham-Coultes, Kelly, Scarcelli, Tiffany, Weng, Ying-Qi, Xhima, Kristiana, O'Reilly, Meaghan, Huang, Yuexi, McLaurin, JoAnne, Hynynen, Kullervo et al. · 2013 · Experimental Neurology
37. Targeting amyloid-β in glaucoma treatment
    Li Guo, T.E. Salt, Vy Luong, Nicholas William Wood, William Cheung, Annelie Maaß, Giulio Ferrari, Françoise Russo‐Marie, Adam Murdin Sillito, Michael E. Cheetham et al. · 2007 · Proceedings of the National Academy of Sciences
38. Microglial Activation and β-Amyloid Deposit Reduction Caused by a Nitric Oxide-Releasing Nonsteroidal Anti-Inflammatory Drug in Amyloid Precursor Protein Plus Presenilin-1 Transgenic Mice
    Paul T. Jantzen, Karen E. Connor, Giovanni DiCarlo, Gary L. Wenk, John Lawrence Wallace, Amyn M. Rojiani, Domenico Coppola, David Morgan, Marcia N. Gordon · 2002 · Journal of Neuroscience
39. Transgenic mouse models of Alzheimer’s disease.
    Elder, Gregory A., Gama Sosa, Miguel A., De Gasperi, Rita · 2010 · Mount Sinai Journal of Medicine A Journal of Translational and Personalized Medicine
40. Drug development for CNS disorders: strategies for balancing risk and reducing attrition
    Menelas N. Pangalos, Lee E. Schechter, Orest Hurko · 2007 · Nature Reviews Drug Discovery
41. Immunology and immunotherapy of Alzheimer's disease
    Weiner, Howard L., Frenkel, Dan · 2006 · Nature Reviews Immunology
42. Glatiramer acetate fights against Alzheimer’s disease by inducing dendritic-like microglia expressing insulin-like growth factor 1
    Butovsky, Oleg, Koronyo-Hamaoui, Maya, Kunis, Gilad, Ophir, Eran, Landa, Gennady, Cohen, Hagit, Schwartz, Michal · 2006 · Proceedings of the National Academy of Sciences
43. Increased T cell reactivity to amyloid β protein in older humans and patients with Alzheimer disease
    Monsonego, Alon, Zota, Victor, Karni, Arnon, Krieger, Jeffery I., Bar-Or, Amit, Bitan, Gal, Budson, Andrew E., Sperling, Reisa, Selkoe, Dennis J., Weiner, Howard L. · 2003 · Journal of Clinical Investigation
44. Conformational Abs recognizing a generic amyloid fibril epitope
    Brian O’Nuallain, Ronald B. Wetzel · 2002 · Proceedings of the National Academy of Sciences
45. Microglial activation and amyloid‐β clearance induced by exogenous heat‐shock proteins
    Jun‐ichi Kakimura, Yoshihisa Kitamura, Kazuyuki Takata, Masaaki Umeki, Sanae Suzuki, Keiichi Shibagaki, Takashi Taniguchi, Yasuyuki Nomura, Peter J. Gebicke‐Haerter, Mark A. Smith et al. · 2002 · The FASEB Journal
46. Ineffective phagocytosis of amyloid-β by macrophages of Alzheimer's disease patients
    Milan Fiala, Justin Lin, John Matthew Ringman, Vali Kermani-Arab, George Tsao, Amish J. Patel, A. S. Lossinsky, Michael C. Graves, Andrew R. Gustavson, James William Sayre et al. · 2005 · Journal of Alzheimer s Disease
47. Inflammaging as a prodrome to Alzheimer's disease
    Giunta, Brian, Fernandez, Francisco, Nikolic, William V, Obregon, Demian, Rrapo, Elona, Town, Terrence, Tan, Jun · 2008 · Journal of Neuroinflammation
48. Novel Therapeutic Approach for the Treatment of Alzheimer's Disease by Peripheral Administration of Agents with an Affinity to β-Amyloid
    Yasuji Matsuoka, Mitsuo Saito, John J. LaFrancois, Mariko Saito, Kate Gaynor, Vicki Olm, Lili Wang, Evelyn Casey, Yifan Lu, Chiharu Shiratori et al. · 2003 · Journal of Neuroscience
49. New pharmacological strategies for treatment of Alzheimer's disease: focus on disease modifying drugs
    Salvatore Salomone, Filippo Caraci, Gian Marco Leggio, Julia Fedotova, Filippo Drago · 2011 · British Journal of Clinical Pharmacology
50. IFN-γ Production by Amyloid β–Specific Th1 Cells Promotes Microglial Activation and Increases Plaque Burden in a Mouse Model of Alzheimer’s Disease
    Tara C. Browne, Keith McQuillan, Róisín M. McManus, Julie-Ann O’Reilly, Kingston H. G. Mills, Marina A. Lynch · 2013 · The Journal of Immunology
51. Amyloid β Protein Dimer-Containing Human CSF Disrupts Synaptic Plasticity: Prevention by Systemic Passive Immunization
    Klyubin, Igor, Betts, Vicki, Welzel, Alfred T., Blennow, Kaj, Zetterberg, Henrik, Wallin, Anders, Lemere, Cynthia A., Cullen, William K., Peng, Ying, Wisniewski, Thomas et al. · 2008 · The Journal of Neuroscience
52. Exacerbation of Cerebral Amyloid Angiopathy-Associated Microhemorrhage in Amyloid Precursor Protein Transgenic Mice by Immunotherapy Is Dependent on Antibody Recognition of Deposited Forms of Amyloid β
    Racke, Margaret M., Boone, Laura I., Hepburn, Deena L., Parsadainian, Maia, Bryan, Matthew T., Ness, Daniel K., Piroozi, Kathy S., Jordan, William H., Brown, Donna D., Hoffman, Wherly P. et al. · 2005 · The Journal of Neuroscience
53. Antibody-Aided Clearance of Extracellular α-Synuclein Prevents Cell-to-Cell Aggregate Transmission
    Bae, Eun-Jin, Lee, He-Jin, Rockenstein, Edward, Ho, Dong-Hwan, Park, Eun-Bi, Yang, Na-Young, Desplats, Paula, Masliah, Eliezer, Lee, Seung-Jae · 2012 · The Journal of Neuroscience
54. Intravenous immunoglobulins containing antibodies against -amyloid for the treatment of Alzheimer's disease
    Richard C. Dodel · 2004 · Journal of Neurology Neurosurgery & Psychiatry
55. Distinct and Non-Redundant Roles of Microglia and Myeloid Subsets in Mouse Models of Alzheimer's Disease
    Mildner, Alexander, Schlevogt, Bernhard, Kierdorf, Katrin, Böttcher, Chotima, Erny, Daniel, Kummer, Markus P., Quinn, Michael, Brück, Wolfgang, Bechmann, Ingo, Heneka, Michael T. et al. · 2011 · The Journal of Neuroscience
56. Consequence of Aβ immunization on the vasculature of human Alzheimer's disease brain
    Delphine Boche, E. Zotova, Roy O. Weller, Seth Love, Jim W. Neal, Ruth M. Pickering, D. Wilkinson, Clive Holmes, James A. R. Nicoll · 2008 · Brain
57. Role of complement in neurodegeneration and neuroinflammation
    Domenico Marco Bonifati, Uday Kishore · 2006 · Molecular Immunology
58. The LPS receptor (CD14) links innate immunity with Alzheimer's disease
    Fassbender, K., Walter, S., Kühl, S., Landmann, R., Ishii, K., Bertsch, T., Stalder, A.K., Muehlhauser, F., Liu, Y., Ulmer, A.J. et al. · 2004 · The FASEB Journal
59. The Binding of 2-(4′-Methylaminophenyl)Benzothiazole to Postmortem Brain Homogenates Is Dominated by the Amyloid Component
    William Edward Klunk, Yanming Wang, Guo-Feng Huang, Manik L. Debnath, Daniel P. Holt, Li Shao, Ronald L. Hamilton, Miloš D. Ikonomović, Steven Trent DeKosky, Chester A. Mathis · 2003 · Journal of Neuroscience
60. Targeting soluble Aβ peptide with Tramiprosate for the treatment of brain amyloidosis
    Francine Gervais, Julie Paquette, Céline Morissette, Pascale Krzywkowski, Mathilde W. N. Yu, Mounia Azzi, Diane Lacombe, Xianqi Kong, Ahmed M. Aman, Julie Laurin et al. · 2006 · Neurobiology of Aging
61. Passive immunization targeting pathological phospho‐tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain
    Boutajangout, Allal, Ingadottir, Johanna, Davies, Peter, Sigurdsson, Einar M. · 2011 · Journal of Neurochemistry
62. 18-Month study of intravenous immunoglobulin for treatment of mild Alzheimer disease
    Norman R. Relkin, Paul Szabo, Basia Adamiak, Tuna Burgut, Carmen Monthé, Richard W. Lent, Steven G. Younkin, Linda H. Younkin, Richard I. Schiff, Marc E. Weksler · 2008 · Neurobiology of Aging
63. BACE1 inhibitors: Current status and future directions in treating Alzheimer's disease
    Nour M. Moussa‐Pacha, Shifaa M. Abdin, Hany A. Omar, Hasan Yaser Alniss, Taleb H. Al‐Tel · 2019 · Medicinal Research Reviews
64. Microglia actions in Alzheimer's disease
    Prokop, Stefan, Miller, Kelly R., Heppner, Frank L. · 2013 · Acta Neuropathologica
65. Passive Amyloid Immunotherapy Clears Amyloid and Transiently Activates Microglia in a Transgenic Mouse Model of Amyloid Deposition
    Donna M. Wilcock, Amyn M. Rojiani, Arnon Rosenthal, Gil Levkowitz, Sangeetha Subbarao, Jennifer Alamed, David H. Wilson, Nedda Wilson, Melissa J. Freeman, Marcia N. Gordon et al. · 2004 · Journal of Neuroscience
66. Microglial phagocytosis induced by fibrillar β-amyloid is attenuated by oligomeric β-amyloid: implications for Alzheimer’s disease
    Pan, Xiao-dong, Zhu, Yuan-gui, Lin, Nan, Zhang, Jing, Ye, Qin-yong, Huang, Hua-pin, Chen, Xiao-chun · 2011 · Molecular Neurodegeneration
67. Amyloid-β: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-β
    Craig Atwood, Mark E. Obrenovich, Tianbing Liu, Hsien Chan, George L. Perry, Mark A. Smith, Ralph Nigel Martins · 2003 · Brain Research Reviews
68. Passive Immunization with Tau Oligomer Monoclonal Antibody Reverses Tauopathy Phenotypes without Affecting Hyperphosphorylated Neurofibrillary Tangles
    Castillo-Carranza, Diana L., Sengupta, Urmi, Guerrero-Muñoz, Marcos J., Lasagna-Reeves, Cristian A., Gerson, Julia E., Singh, Gurpreet, Estes, D. Mark, Barrett, Alan D. T., Dineley, Kelly T., Jackson, George R. et al. · 2014 · The Journal of Neuroscience
69. Immunotherapeutic Approaches for Alzheimer’s Disease
    Wisniewski, Thomas, Goñi, Fernando · 2015 · Neuron
70. Spontaneous Hemorrhagic Stroke in a Mouse Model of Cerebral Amyloid Angiopathy
    David T. Winkler, Luca Bondolfi, Martin C. Herzig, Lukas Jann, Michael E. Calhoun, Karl‐Heinz Wiederhold, Markus Tolnay, Matthias Staufenbiel, Mathias Jucker · 2001 · Journal of Neuroscience
71. Generation of antibodies specific for β-amyloid by vaccination of patients with Alzheimer disease
    Christoph Höck, Uwe Konietzko, Andreas Papassotiropoulos, Axel Wollmer, Johannes Rolf Streffer, Ruth C. von Rotz, Gabriela E. Davey, Eva Moritz, Roger M. Nitsch · 2002 · Nature Medicine
72. Reduction of Soluble Aβ and Tau, but Not Soluble Aβ Alone, Ameliorates Cognitive Decline in Transgenic Mice with Plaques and Tangles
    Salvatore Oddo, Vitaly Vasilevko, Antonella Caccamo, Masashi Kitazawa, David H. Cribbs, Frank M. LaFerla · 2006 · Journal of Biological Chemistry
73. Tau-based therapies in neurodegeneration: opportunities and challenges
    Li, Chuanzhou, Götz, Jürgen · 2017 · Nature Reviews Drug Discovery
74. Adjuvant-dependent modulation of Th1 and Th2 responses to immunization with beta-amyloid
    David H. Cribbs · 2003 · International Immunology
75. Safety and biomarker effects of solanezumab in patients with Alzheimer's disease
    Martin Rhys Farlow, Steven Edward Arnold, Christopher H. van Dyck, Paul S. S. Aisen, B. Joy Snider, Anton P. Porsteinsson, Stuart W. Friedrich, Robert A. Dean, Celedon Gonzales, Gopalan Sethuraman et al. · 2012 · Alzheimer s & Dementia
76. Vascular Dysfunction in Alzheimer’s Disease: A Prelude to the Pathological Process or a Consequence of It?
    Karan Govindpani, Laura G McNamara, Nicholas R Smith, Chitra Vinnakota, Henry John Waldvogel, Richard L. M. Faull, Andrea Kwakowsky · 2019 · Journal of Clinical Medicine
77. A critique of the drug discovery and phase 3 clinical programs targeting the amyloid hypothesis for Alzheimer disease
    Eric H. Karran, John Hardy · 2014 · Annals of Neurology
78. Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy
    Jürgen Götz, Johannes Rolf Streffer, Della C. David, A Schild, Frédéric J. Hoerndli, Luis Pennanen, Pascal Kurosinski, F Chen · 2004 · Molecular Psychiatry
79. Monoclonal antibodies that target pathological assemblies of Aβ
    Lambert, Mary P., Velasco, Pauline T., Chang, Lei, Viola, Kirsten L., Fernandez, Sara, Lacor, Pascale N., Khuon, Daliya, Gong, Yuesong, Bigio, Eileen H., Shaw, Pamela et al. · 2007 · Journal of Neurochemistry
80. Neurotrophic cross‐talk between the nervous and immune systems: Implications for neurological diseases
    Martin Kerschensteiner, Christine Stadelmann, Georg Dechant, Hartmut Wekerle, Reinhard Hohlfeld · 2003 · Annals of Neurology
81. Structural pathways for macromolecular and cellular transport across the blood-brain barrier during inflammatory conditions. Review.
    A. S. Lossinsky, Richard R. Shivers · 2004 · PubMed
82. Inhibition of Amyloid Formation
    Torleif Härd, Christofer Lendel · 2012 · Journal of Molecular Biology
83. Biomarkers of Alzheimer disease in plasma
    Michael C. Irizarry · 2004 · NeuroRx
84. Expression of the neonatal Fc receptor (FcRn) at the blood–brain barrier
    Felix Schlachetzki, Chunni Zhu, William M. Pardridge · 2002 · Journal of Neurochemistry
85. Aβ-degrading enzymes: potential for treatment of Alzheimer disease
    Miners, James Scott, Barua, Neil, Kehoe, Patrick Gavin, Gill, Steven, Love, Seth · 2011 · Journal of Neuropathology &amp; Experimental Neurology
86. Aβ Species Removal After Aβ ₄₂ Immunization
    Nicoll, James A. R., Barton, Edward, Boche, Delphine, Neal, Jim W., Ferrer, Isidro, Thompson, Petrina, Vlachouli, Christina, Wilkinson, David, Bayer, Antony, Games, Dora et al. · 2006 · Journal of Neuropathology &amp; Experimental Neurology
87. Immunotherapy for Alzheimer’s disease: targeting β-amyloid and beyond
    Song, Chenghuan, Shi, Jiyun, Zhang, Pingao, Zhang, Yongfang, Xu, Jianrong, Zhao, Lanxue, Zhang, Rui, Wang, Hao, Chen, Hongzhuan · 2022 · Translational Neurodegeneration
88. Non-Fc-Mediated Mechanisms Are Involved in Clearance of Amyloid-β<i>In Vivo</i>by Immunotherapy
    Bacskai, Brian J., Kajdasz, Stephen T., McLellan, Megan E., Games, Dora, Seubert, Peter, Schenk, Dale, Hyman, Bradley T. · 2002 · The Journal of Neuroscience
89. Microglia and neuroprotection: From in vitro studies to therapeutic applications
    Elisabetta Polazzi, Barbara Monti · 2010 · Progress in Neurobiology
90. Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy
    Theunis, Clara, Crespo-Biel, Natalia, Gafner, Valérie, Pihlgren, Maria, López-Deber, María Pilar, Reis, Pedro, Hickman, David T., Adolfsson, Oskar, Chuard, Nathalie, Ndao, Dorin Mlaki et al. · 2013 · PLoS ONE
91. Partial Reduction of BACE1 Has Dramatic Effects on Alzheimer Plaque and Synaptic Pathology in APP Transgenic Mice
    McConlogue, Lisa, Buttini, Manuel, Anderson, John P., Brigham, Elizabeth F., Chen, Karen S., Freedman, Stephen B., Games, Dora, Johnson-Wood, Kelly, Lee, Michael, Zeller, Michelle et al. · 2007 · Journal of Biological Chemistry
92. Plaque‐associated disruption of CSF and plasma amyloid‐β (Aβ) equilibrium in a mouse model of Alzheimer's disease
    Ronald Bradley Demattos, Kelly R. Bales, Maia Parsadanian, Mark A. O'Dell, Eric M. Foss, Steven M. Paul, David M. Holtzman · 2002 · Journal of Neurochemistry
93. Inflammation in Alzheimer's disease: relevance to pathogenesis and therapy
    Elina Zotova, James A. R. Nicoll, Raj N. Kalaria, Clive Holmes, Delphine Boche · 2010 · Alzheimer s Research & Therapy
94. Immunization with a Nontoxic/Nonfibrillar Amyloid-β Homologous Peptide Reduces Alzheimer's Disease-Associated Pathology in Transgenic Mice
    Einar M. Sigurdsson, Henrieta Scholtzova, Pankaj D Mehta, Blas Frangione, Thomas Wısnıewskı · 2001 · American Journal Of Pathology
95. Lymphatic drainage system of the brain: A novel target for intervention of neurological diseases
    Bao‐liang Sun, Li-hua Wang, Tuo Yang, Jingyi Sun, Leilei Mao, Mingfeng Yang, Hui Yuan, Robert A. Colvin, Xiaoyi Yang · 2017 · Progress in Neurobiology
96. Inflammatory components in human Alzheimer’s disease and after active amyloid-β42 immunization
    Zotova, Elina, Bharambe, Viraj, Cheaveau, Matthew, Morgan, William, Holmes, Clive, Harris, Scott, Neal, James W., Love, Seth, Nicoll, James A. R., Boche, Delphine · 2013 · Brain
97. Inflammation and therapeutic vaccination in CNS diseases
    Howard L. Weiner, Dennis J. Selkoe · 2002 · Nature
98. Targeting Amyloid-β Peptide (Aβ) Oligomers by Passive Immunization with a Conformation-selective Monoclonal Antibody Improves Learning and Memory in Aβ Precursor Protein (APP) Transgenic Mice
    Edward B. Lee, Lewis Z. Leng, Bin Zhang, Linda K. Kwong, John Q. Trojanowski, Ted G. Abel, Virginia M.‐Y. Lee · 2005 · Journal of Biological Chemistry
99. First‐in‐human assessment of PRX002, an anti–α‐synuclein monoclonal antibody, in healthy volunteers
    Dale B. Schenk, Martin Koller, DANIEL K. NESS, Sue G. Griffith, Michael Grundman, Wagner M. Zago, Jay Soto, George J. Atiee, Susanne Ostrowitzki, Gene G. Kinney · 2016 · Movement Disorders
100. Biological markers for therapeutic trials in Alzheimer’s disease
     Richard Frank, Douglas Galasko, Harald Juergen Hampel, John Hardy, Mony J. de Leon, Pankaj D Mehta, Joseph Rogers, Eric Siemers, John Q. Trojanowski · 2003 · Neurobiology of Aging