Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in β-islet cell hyperplasia

Rane, Sushil G., Dubus, Pierre, Mettus, Richard V., Galbreath, Elizabeth J., Boden, Guenther, Reddy, E. Premkumar, Barbacid, Mariano·1999·Nature Genetics

Cited by (702)

Items 301–400 of 702

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    Jérôme Artus, Michel Cohen‐Tannoudji · 2007 · Molecular and Cellular Endocrinology
  2. Gastroenteropancreatic endocrine tumors
    C. Weil · 1985 · Journal of Molecular Medicine
  3. Genetic Characterization of the Role of the Cip/Kip Family of Proteins as Cyclin-Dependent Kinase Inhibitors and Assembly Factors
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  4. DNA Methylation Patterning and the Regulation of Beta Cell Homeostasis
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  5. Type 2 diabetes and polymorphisms on chromosome 9p21: A meta-analysis
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  6. The Cell Cycle Inhibitory Protein p21cip Is Not Essential for Maintaining β-Cell Cycle Arrest or β-Cell Function In Vivo
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  7. Lack of p19INK4d in human testicular germ-cell tumours contrasts with high expression during normal spermatogenesis
    Jiřina Bártková, Minna Thullberg, Ewa Rajpert‐De Meyts, Niels Erik Skakkebæk, Jiri Bartek · 2000 · Oncogene
  8. Inducible deletion of CDK4 and CDK6 – deciphering CDK4/6 inhibitor effects in the hematopoietic system
    Barbara Maurer, Tania Brandstoetter, Sebastian Kollmann, Veronika Sexl, Michaela Prchal‐Murphy · 2020 · Haematologica
  9. Role of cell cycle regulators in adipose tissue and whole body energy homeostasis
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  10. A new era for Type 2 diabetes genetics
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  12. Conditional inactivation of Myc impairs development of the exocrine pancreas
    H. Nakhai, J. Siveke, L. Mendoza-Torres, R. Schmid · 2008 · Development
  13. Genetic Evidence for Functional Dependency of p18Ink4c on Cdk4
    Xin‐Hai Pei, Feng Bai, Tateki Tsutsui, Hiroaki Kiyokawa, Yue Xiong · 2004 · Molecular and Cellular Biology
  14. Role of key regulators of the cell cycle in maintenance of hematopoietic stem cells
    Akinobu Matsumoto, Keiichi I. Nakayama · 2012 · Biochimica et Biophysica Acta (BBA) - General Subjects
  15. The retinoblastoma protein—from bench to bedside
    Sibylle Mittnacht · 2005 · European Journal of Cell Biology
  16. p53-independent induction of p21waf1/cip1 contributes to the activation of caspases in GTP-depletion-induced apoptosis of insulin-secreting cells
    Jianxin Huo, Stewart A. Metz, G D Li · 2003 · Cell Death and Differentiation
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  18. Out of the cycle: Impact of cell cycle aberrations on cancer metabolism and metastasis
    Alvin H.K. Cheung, Chris Ho‐Lam Hui, Kit Yee Wong, Xiaoli Liu, Bonan Chen, Wei Kang, Ka Fai To · 2022 · International Journal of Cancer
  19. Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B
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  20. Regulating mitosis and meiosis in the male germ line: critical functions for cyclins
    Debra J. Wolgemuth, Shelby S. Roberts · 2010 · Philosophical Transactions of the Royal Society B Biological Sciences
  21. Agaricus bisporus lectins mediates islet β -cell proliferation through regulation of cell cycle proteins
    Yi Wang, Yuande Liu, Hailian Wang, Chunyang Li, Ping Qi, Jinku Bao · 2012 · Experimental Biology and Medicine
  22. An oncologist׳s friend: How Xenopus contributes to cancer research
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  23. JAK/STAT signaling regulates tissue outgrowth and male germline stem cell fate in Drosophila
    Shree Ram Singh, Xiu Chen, Xianyu Steven Hou · 2005 · Cell Research
  24. MEN1 tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2
    M P Gillam, Dipali Nimbalkar, Limin Sun, Konstantin T. Christov, Dipankar Ray, Philipp Kaldis, Xiaoqiu Liu, Hiroaki Kiyokawa · 2014 · Oncogene
  25. Cdk2 and Cdk4 cooperatively control the expression of Cdc2.
    Cyril Berthet, Philipp Kaldis · 2006 · Cell Division
  26. Inhibitor Selectivity for Cyclin‐Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study
    Pascale Hazel, Sebastian H. B. Kroll, Alexander Bondke, Marion Barbazanges, Hetal Patel, Matthew John Fuchter, R. Charles Coombes, Simak Ali, Anthony G. M. Barrett, Paul S. Freemont · 2017 · ChemMedChem
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  30. Cell Cycle and Cancer: Genetic Analysis of the Role of Cyclin-dependent Kinases
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  31. Regulation of the Embryonic Cell Cycle During Mammalian Preimplantation Development
    Nathan Palmer, Philipp Kaldis · 2016 · Current topics in developmental biology/Current Topics in Developmental Biology
  32. Loss of Cyclin-dependent Kinase 2 in the Pancreas Links Primary β-Cell Dysfunction to Progressive Depletion of β-Cell Mass and Diabetes
    So Yoon Kim, Ji-Hyeon Lee, Matthew J. Merrins, Oksana Gavrilova, Xavier Bisteau, Philipp Kaldis, Leslie S. Satin, Sushil G. Rane · 2017 · Journal of Biological Chemistry
  33. Conditional deletion of p53 and Rb in the renin-expressing compartment of the pancreas leads to a highly penetrant metastatic pancreatic neuroendocrine carcinoma
    Sean T. Glenn, Craig A. Jones, Sandra Sexton, Charles LeVea, Susan M Caraker, George Hajduczok, Kenneth W. Gross · 2013 · Oncogene
  34. Genetic cooperation between p21Cip1 and INK4 inhibitors in cellular senescence and tumor suppression
    Víctor Quereda, Jorge Martinalbo, Pierre R. Dubus, Amancio Carnero, Marcos Malumbres · 2007 · Oncogene
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    Fred Levine, Pamela Itkin‐Ansari · 2007 · Journal of Molecular Medicine
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    Hiroshi Nojima · 2004 · Humana Press eBooks
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    Moritani, Maki, Yamasaki, Seiji, Kagami, Mitsuhiro, Suzuki, Takao, Yamaoka, Takashi, Sano, Toshiaki, Hata, Jun-Ichi, Itakura, Mitsuo · 2005 · Molecular and Cellular Endocrinology
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  40. β-cell proliferation is the major source of new pancreatic β cells
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  41. Enrichment of Putative Pancreatic Progenitor Cells from Mice by Sorting for Prominin1 (CD133) and Platelet-Derived Growth Factor Receptor β
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    YUAN WANG, Haifeng Qiu, Hu Weixu, Shaoru Li, Jinjin Yu · 2014 · Oncology Reports
  45. Strong association of common variants in the CDKN2A/CDKN2B region with type 2 diabetes in French Europids
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  47. Cdk2 and Cdk4 Activities Are Dispensable for Tumorigenesis Caused by the Loss of p53
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  48. Cyclin‐Dependent Kinase 4 Regulates Adult Neural Stem Cell Proliferation and Differentiation in Response to Insulin
    Laura Chirivella, M. Kirstein, S. Ferrón, Ana Domingo-Muelas, Fabrice C. Durupt, Carlos Acosta-Umanzor, M. Cano-Jaimez, F. Pérez-Sánchez, M. Barbacid, Sagrario Ortega et al. · 2017 · Stem Cells
  49. How to make pancreatic β cells — prospects for cell therapy in diabetes
    T. Nir, Y. Dor · 2005 · Current Opinion in Biotechnology
  50. Expression of cyclin D1 and CDK4 causes hypertrophic growth of cardiomyocytes in culture: a possible implication for cardiac hypertrophy
    Mimi Tamamori‐Adachi, Hiroshi Ito, Kiyoshi Nobori, Kentaro Hayashida, Junya Kawauchi, Susumu Adachi, Masa-Aki Ikeda, Shigetaka Kitajima · 2002 · Biochemical and Biophysical Research Communications
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    Marcos Malumbres, Sarah L. Hunt, Rocı́o Sotillo, Javier Martín‐Broto, Jun Odajima, Alberto Lancina Martín, Pierre R. Dubus, Sagrario Ortega, Mariano Barbacid · 2003 · Advances in experimental medicine and biology
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  53. FTO, GCKR, CDKAL1 and CDKN2A/B gene polymorphisms and the risk of gestational diabetes mellitus: a meta-analysis
    Fang Guo, Wei Long, Wenbai Zhou, Bin Zhang, Jianbing Liu, Bin Yu · 2018 · Archives of Gynecology and Obstetrics
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    Jussara Hagen, Viviane Palhares Muniz, Kelly C. Falls, Sara M. Reed, Agshin F. Taghiyev, Frederick W. Quelle, Françoise A. Gourronc, Aloysius John Klingelhutz, Heather J. Major, Ryan W. Askeland et al. · 2014 · Cancer Research
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    Michelle L. Churchman, Ignasi Roig, Maria Jasin, Scott Keeney, Charles J. Sherr · 2011 · PLoS Genetics
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    Lin Wang, Rui Zhang, Xue You, Huanhuan Zhang, Siying Wei, Tingting Cheng, Qianqian Cao, Zhenzhen Wang, Yan Chen · 2017 · Journal of Molecular Cell Biology
  57. Activation of Caspase-2 Mediates the Apoptosis Induced by GTP-Depletion in Insulin-Secreting (HIT-T15) Cells
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    Józefa Węsierska‐Gądek, Gerald Schmid · 2005 · Expert Opinion on Investigational Drugs
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  89. Molecular Regulation of Pancreas Development in Zebrafish
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    Suzana Atanasoski, Matthias Boentert, Lukas De Ventura, Hartmut Pohl, Constanze Baranek, Konstantin Beier, Peter Young, Mariano Barbacid, Ueli Suter · 2007 · Molecular and Cellular Neuroscience
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