The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.
Hypertriglyceridemic Pancreatitis: Presentation and Management
Abstract
Hypertriglyceridemia (HTG) is reported to cause 1-4% of acute pancreatitis (AP) episodes. HTG is also implicated in more than half of gestational pancreatitis cases. Disorders of lipoprotein metabolism are conventionally divided into primary (genetic) and secondary causes, including diabetes, hypothyroidism, and obesity. Serum triglyceride (TG) levels above 1,000 mg/dl are usually considered necessary to ascribe causation for AP. The mechanism for hypertriglyceridemic pancreatitis (HTGP) is postulated to involve hydrolysis of TG by pancreatic lipase and release of free fatty acids that induce free radical damage. Multiple small studies on HTGP management have evaluated the use of insulin, heparin, or both. Many series have also reported use of apheresis to reduce TG levels. Subsequent control of HTG with dietary restrictions, antihyperlipidemic agents, and even regular apheresis has been shown anecdotally in case series to prevent future episodes of AP. However, large multicenter studies are needed to optimize future management guidelines for patients with HTGP.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Mechanism of Action of Fibrates on Lipid and Lipoprotein Metabolism
Staels, B., Dallongeville, J., Auwerx, J., Schoonjans, K., Leitersdorf, E., & Fruchart, J.-C. (1998) · Circulation · doi:10.1161/01.cir.98.19.2088 · Cited by 1,786
Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis
Goldberg, I. J. (1996) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37569-6 · Cited by 1,010
Flier, J. S., Underhill, L. H., & Eckel, R. H. (1989) · New England Journal of Medicine · doi:10.1056/nejm198904203201607 · Cited by 971
CLEARING FACTOR, A HEPARIN-ACTIVATED LIPOPROTEIN LIPASE
Korn, E. D. (1955) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)66011-9 · Cited by 853
Warnick, G. R., Knopp, R. H., Fitzpatrick, V, & Branson, L. (1990) · Clinical Chemistry · doi:10.1093/clinchem/36.1.15 · Cited by 567
Szczepiorkowski, Z. M., Bandarenko, N., Kim, H. C., Linenberger, M. L., Marques, M. B., Sarode, R., Schwartz, J., Shaz, B. H., Weinstein, R., Wirk, A., et al. (2007) · Journal of Clinical Apheresis · doi:10.1002/jca.20129 · Cited by 546
Issues in Hyperlipidemic Pancreatitis
Yadav, D., & Pitchumoni, C. S. (2003) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-200301000-00016 · Cited by 435
(1995) · PubMed · Cited by 423
Toskes, P. P. (1990) · Gastroenterology Clinics of North America · doi:10.1016/s0889-8553(21)00513-6 · Cited by 339
Durrington, P. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14234-1 · Cited by 307
Cited by
Current knowledge of hypertriglyceridemic pancreatitis
Valdivielso, P., Ramírez-Bueno, A., & Ewald, N. (2014) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2014.08.008 · Cited by 439
Graham, M. J., Lee, R. G., Bell, T. A., Fu, W., Mullick, A. E., Alexander, V. J., Singleton, W., Viney, N., Geary, R., Su, J., et al. (2013) · Circulation Research · doi:10.1161/circresaha.111.300367 · Cited by 377
Nawaz, H., Koutroumpakis, E., Easler, J., Slivka, A., Whitcomb, D. C., Singh, V. P., Yadav, D., & Papachristou, G. I. (2015) · American Journal of Gastroenterology · doi:10.1038/ajg.2015.261 · Cited by 296
Severe hypertriglyceridemia and pancreatitis: presentation and management
Ewald, N., Hardt, P. D., & Kloer, H.-U. (2009) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e3283319a1d · Cited by 273
Hypertriglyceridemic pancreatitis: Epidemiology, pathophysiology and clinical management
de Pretis, N., Amodio, A., & Frulloni, L. (2018) · United European Gastroenterology Journal · doi:10.1177/2050640618755002 · Cited by 265
Metadata
- Authors
- Tsuang, W., Navaneethan, U., Ruiz, L., Palascak, J. B., & Gelrud, A.
- Venue
- The American Journal of Gastroenterology
- Published
- 2009-03-17
- Volume
- 104
- Issue
- 4
- Pages
- 984-991
- ISSN
- 0002-9270 (ISSN-L)
- 1572-0241
- OpenAlex
- W1982477772
- Cited by
- 395
- References
- 73
- FWCI
- 21.22
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Hypertriglyceridemic Pancreatitis: Presentation and Management. https://app.cochat.ai/papers/10.1038/ajg.2009.27
- The paper
- Tsuang, W., Navaneethan, U., Ruiz, L., Palascak, J. B., & Gelrud, A. (2009). Hypertriglyceridemic Pancreatitis: Presentation and Management. The American Journal of Gastroenterology. https://doi.org/10.1038/ajg.2009.27
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
