The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Inflammatory bowel disease, irritable bowel syndrome, or what: a challenge to the functional-organic dichotomy.
Abstract
Many patients with inflammatory bowel disease (IBD) in clinical remission continue to have symptoms of pain and diarrhea despite minimal or no ongoing inflammation. These patients may be considered to have an overlap of IBD and irritable bowel syndrome (IBD-IBS). In this month's Journal, a proposal is made that continued symptoms in patients with elevated calprotectin, a marker of inflammation, is related to IBD. We propose an alternate biopsychosocial model whereby mutual effects of peripheral and central factors influence symptom generation in both IBD and IBS. Understanding this model has important implications for treatment of patients with IBD-IBS.
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“Given this prevalence, it is unlikely that IBD patients are protected from IBS.2”
From Tricyclic Antidepressants for Management of Residual Symptoms in Inflammatory Bowel Disease (2014) · cites this paper as [2]
Citations
Cites
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Self-citationStress and Exacerbation in Ulcerative Colitis: A Prospective Study of Patients Enrolled in Remission
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Self-citationWhat determines severity among patients with painful functional bowel disorders?
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Self-citationGrover, M., Herfarth, H., & Drossman, D. (2009) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2008.08.032 · Cited by 131
Self-citationDrossman, D. A. (2005) · Gut · doi:10.1136/gut.2004.058446 · Cited by 74
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Effects of Stress on Intestinal Mucosal Functions
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Enck, P., Aziz, Q., Barbara, G., Farmer, A. D., Fukudo, S., Mayer, E. A., Niesler, B., Quigley, E. M. M., Rajilić-Stojanović, M. D., Schemann, M., et al. (2016) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2016.14 · Cited by 1,102
Halpin, S. J., & Ford, A. C. (2012) · American Journal of Gastroenterology · doi:10.1038/ajg.2012.260 · Cited by 607
A comprehensive review and update on Crohn's disease
Gajendran, M., Loganathan, P., Catinella, A. P., & Hashash, J. G. (2017) · Disease-a-Month · doi:10.1016/j.disamonth.2017.07.001 · Cited by 553
Gracie, D. J., Hamlin, P. J., & Ford, A. C. (2019) · The Lancet. Gastroenterology & hepatology · doi:10.1016/s2468-1253(19)30089-5 · Cited by 362
Pellissier, S., Dantzer, C., Mondillon, L., Trocme, C., Gauchez, A.-S., Ducros, V., Mathieu, N., Toussaint, B., Fournier, A., Canini, F., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0105328 · Cited by 212
Metadata
- Authors
- Long, M. D., & Drossman, D. A.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- Corresponding author
- Drossman, Douglas A
- Venue
- American Journal of Gastroenterology
- Published
- 2010-08
- Volume
- 105
- Issue
- 8
- Pages
- 1796-1798
- ISSN
- 0002-9270 (ISSN-L)
- OpenAlex
- W47476788
- Cited by
- 101
- References
- 22
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 1 · 2022: 6 · 2021: 7 · 2020: 6 · 2019: 10 · 2018: 8 · 2017: 9 · 2016: 7 · 2015: 7 · 2014: 8 · 2013: 8 · 2012: 9
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The American Journal of Gastroenterology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Gastroenterology › Microscopic Colitis
- Keywords
- inflammatory bowel disease, irritable bowel syndrome, calprotectin, biopsychosocial model, chronic pain, diarrhea, clinical remission, symptom generation
- MeSH terms
- Colitis, Ulcerative, Crohn Disease, Diagnosis, Differential, Feces, Humans, Quality of Life, Risk Factors, Stress, Psychological, Biomarkers, Cytokines, Leukocyte L1 Antigen Complex, Irritable Bowel Syndrome
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