The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Acute lymphoblastic leukemia: a comprehensive review and 2017 update
Open accessAbstract
Acute lymphoblastic leukemia (ALL) is the second most common acute leukemia in adults, with an incidence of over 6500 cases per year in the United States alone. The hallmark of ALL is chromosomal abnormalities and genetic alterations involved in differentiation and proliferation of lymphoid precursor cells. In adults, 75% of cases develop from precursors of the B-cell lineage, with the remainder of cases consisting of malignant T-cell precursors. Traditionally, risk stratification has been based on clinical factors such age, white blood cell count and response to chemotherapy; however, the identification of recurrent genetic alterations has helped refine individual prognosis and guide management. Despite advances in management, the backbone of therapy remains multi-agent chemotherapy with vincristine, corticosteroids and an anthracycline with allogeneic stem cell transplantation for eligible candidates. Elderly patients are often unable to tolerate such regimens and carry a particularly poor prognosis. Here, we review the major recent advances in the treatment of ALL.
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Cites
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Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
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Cited by
Shah, B. D., Ghobadi, A., Oluwole, O. O., Logan, A. C., Boissel, N., Cassaday, R. D., Leguay, T., Bishop, M. R., Topp, M. S., Tzachanis, D., et al. (2021) · The Lancet · doi:10.1016/s0140-6736(21)01222-8 · Cited by 820
Integrating evolutionary dynamics into cancer therapy
Gatenby, R. A., & Brown, J. S. (2020) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-020-0411-1 · Cited by 227
Small Non-Coding RNAs in Leukemia
Balatti, V., & Croce, C. M. (2022) · Cancers · doi:10.3390/cancers14030509 · Cited by 14
Biology and Therapeutic Properties of Mesenchymal Stem Cells in Leukemia
Wu, C.-H., Weng, T.-F., Li, J.-P., & Wu, K.-H. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25052527 · Cited by 13
Flores-López, L. A., De la Mora-De la Mora, I., Malagón-Reyes, C. M., García-Torres, I., Martínez-Pérez, Y., López-Herrera, G., Hernández-Alcántara, G., León-Avila, G., López-Velázquez, G., Olaya-Vargas, A., et al. (2024) · Biomolecules · doi:10.3390/biom14101295 · Cited by 6
Metadata
- Authors
- Terwilliger, T., & Abdul-Hay, M.
- Venue
- Blood Cancer Journal
- Published
- 2017-06-30
- Volume
- 7
- Issue
- 6
- Pages
- e577-e577
- ISSN
- 2044-5385 (ISSN-L)
- OpenAlex
- W2725970815
- Cited by
- 1,288
- References
- 6
- FWCI
- 80.60
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
