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Cited by 509

The DOI matches its Crossref record.

The Effects of the Inhalation of Asbestos in Rats

Open access
Wagner, J C, Berry, G, Skidmore, J W, Timbrell, V·1974·British Journal of Cancer
DOI 10.1038/bjc.1974.65
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Abstract

Two experiments in which SPF Wistar rats were exposed by inhalation to dust clouds of the UICC standard reference samples for periods of between one day and 2 years are described. All the samples of asbestos produced asbestosis which continued to progress after removal from exposure but only a little fibrosis was observed in control rats. Lung tumours, ranging in severity from adenomata to squamous carcinomata, were produced by all samples but in the controls there were only a few adenomata and none of the more serious tumours. Of the 20 tumours which metastasized, 16 occurred after exposure to one or other of the 2 chrysotile samples. In addition, a total of 11 mesotheliomata occurred, 4 of which were with crocidolite and 4 with Canadian chrysotile. Two of the mesotheliomata occurred with only one day's exposure to asbestos. There was a positive association between asbestosis and lung tumours.

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Metadata

Authors
Wagner, J. C., Berry, G., Skidmore, J. W., & Timbrell, V
Venue
British Journal of Cancer
Publisher
Springer Science and Business Media LLC
Published
1974-03
Volume
29
Issue
3
Pages
252-269
ISSN
  • 0007-0920 (ISSN-L)
  • 1532-1827
DOI
10.1038/bjc.1974.65
OpenAlex
W2030647754
Cited by
509
References
0
FWCI
12.80
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The Effects of the Inhalation of Asbestos in Rats. https://app.cochat.ai/papers/10.1038/bjc.1974.65
The paper
Wagner, J. C., Berry, G., Skidmore, J. W., & Timbrell, V. (1974). The Effects of the Inhalation of Asbestos in Rats. British Journal of Cancer. https://doi.org/10.1038/bjc.1974.65

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.