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Prognostic significance of interleukin 6 serum levels in patients with ovarian cancer
Open accessAbstract
High levels of IL-6 were found in 50% of 114 patients with primary ovarian cancer. IL-6 sensitivity was lower than that of CA 125, and the combination of both assays did not increase the sensitivity of CA 125 alone. However, elevated IL-6 serum levels were correlated with a poor prognosis since patients with low IL-6 levels had a better survival than patients with high IL-6 levels (P = 0.0009). Multivariate analysis revealed that IL-6 positivity has an independent value.
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Citations
Cited by
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Balkwill, F. R., & Mantovani, A. (2012) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2011.12.005 · Cited by 685
Michalaki, V, Syrigos, K., Charles, P., & Waxman, J. (2004) · British Journal of Cancer · doi:10.1038/sj.bjc.6601814 · Cited by 406
Lippitz, B. E., & Harris, R. A. (2016) · OncoImmunology · doi:10.1080/2162402x.2015.1093722 · Cited by 248
Psychosocial factors and interleukin-6 among women with advanced ovarian cancer
Costanzo, E. S., Lutgendorf, S. K., Sood, A. K., Anderson, B., Sorosky, J., & Lubaroff, D. M. (2005) · Cancer · doi:10.1002/cncr.21147 · Cited by 217
Metadata
- Authors
- Scambia, G., Testa, U., Benedetti Panici, P., Foti, E., Martucci, R., Gadducci, A., Perillo, A., Facchini, V, Peschle, C., & Mancuso, S.
- Venue
- British Journal of Cancer
- Published
- 1995-02
- Volume
- 71
- Issue
- 2
- Pages
- 354-356
- ISSN
- 0007-0920 (ISSN-L)
- 1532-1827
- OpenAlex
- W2007876410
- Cited by
- 198
- References
- 0
- FWCI
- 3.24
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Scambia, G., Testa, U., Benedetti Panici, P., Foti, E., Martucci, R., Gadducci, A., Perillo, A., Facchini, V, Peschle, C., & Mancuso, S. (1995). Prognostic significance of interleukin 6 serum levels in patients with ovarian cancer. British Journal of Cancer. https://doi.org/10.1038/bjc.1995.71
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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