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Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually

Open access
for the European Society for Blood and Marrow Transplantation (EBMT), Passweg, J R, Baldomero, H, Bader, P, Bonini, C, Cesaro, S, Dreger, P, Duarte, R F, Dufour, C, Kuball, J, Farge-Bancel, D, Gennery, A, Kröger, N, Lanza, F, Nagler, A, Sureda, A, Mohty, M·2016·Bone Marrow Transplantation

Abstract

A record number of 40 829 hematopoietic stem cell transplantation (HSCT) in 36 469 patients (15 765 allogeneic (43%), 20 704 autologous (57%)) were reported by 656 centers in 47 countries to the 2014 survey. Trends include: continued growth in transplant activity, more so in Eastern European countries than in the west; a continued increase in the use of haploidentical family donors (by 25%) and slower growth for unrelated donor HSCT. The use of cord blood as a stem cell source has decreased again in 2014. Main indications for HSCT were leukemias: 11 853 (33%; 96% allogeneic); lymphoid neoplasias; 20 802 (57%; 11% allogeneic); solid tumors; 1458 (4%; 3% allogeneic) and non-malignant disorders; 2203 (6%; 88% allogeneic). Changes in transplant activity include more allogeneic HSCT for AML in CR1, myeloproliferative neoplasm (MPN) and aplastic anemia and decreasing use in CLL; and more autologous HSCT for plasma cell disorders and in particular for amyloidosis. In addition, data on numbers of teams doing alternative donor transplants, allogeneic after autologous HSCT, autologous cord blood transplants are presented.

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Metadata

Authors
for the European Society for Blood and Marrow Transplantation (EBMT), Passweg, J. R., Baldomero, H., Bader, P., Bonini, C., Cesaro, S., Dreger, P., Duarte, R. F., Dufour, C., Kuball, J., Farge-Bancel, D., Gennery, A., Kröger, N., Lanza, F., Nagler, A., Sureda, A., & Mohty, M.
Venue
Bone Marrow Transplantation
Published
2016-02-22
Volume
51
Issue
6
Pages
786-792
ISSN
  • 0268-3369 (ISSN-L)
  • 1476-5365
OpenAlex
W2284574660
Cited by
402
References
1
FWCI
58.20
Type
journal article
Language
en
Open access
hybrid

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The paper
for the European Society for Blood and Marrow Transplantation (EBMT), Passweg, J. R., Baldomero, H., Bader, P., Bonini, C., Cesaro, S., Dreger, P., Duarte, R. F., Dufour, C., Kuball, J., Farge-Bancel, D., Gennery, A., Kröger, N., Lanza, F., Nagler, A., Sureda, A., & Mohty, M. (2016). Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually. Bone Marrow Transplantation. https://doi.org/10.1038/bmt.2016.20

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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