Mutant p53 protein, master regulator of human malignancies: A report on the Fifth Mutant p53 Workshop

The p53 Pathway in Glioblastoma

Zhang, Y., Dube, C., Gibert, M., Cruickshanks, N., Wang, B., Coughlan, M., Yang, Y., Setiady, I., Deveau, C., Saoud, K., et al. (2018) · Cancers · doi:10.3390/cancers10090297 · Cited by 440 · see citing works

Mutant p53 in Cancer: Accumulation, Gain-of-Function, and Therapy

Yue, X., Zhao, Y., Xu, Y., Zheng, M., Feng, Z., & Hu, W. (2017) · Journal of Molecular Biology · doi:10.1016/j.jmb.2017.03.030 · Cited by 308 · see citing works

Tumor suppressor p53 and metabolism

Liu, J., Zhang, C., Hu, W., & Feng, Z. (2018) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjy070 · Cited by 298 · see citing works

The regulation of MDM2 oncogene and its impact on human cancers

Zhao, Y., Yu, H., & Hu, W. (2014) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmt147 · Cited by 173 · see citing works

TP53 Alterations Correlate with Response to VEGF/VEGFR Inhibitors: Implications for Targeted Therapeutics

Wheler, J. J., Jankú, F., Naing, A., Li, Y., Stephen, B., Zinner, R., Subbiah, V., Fu, S., Karp, D. D., Falchook, G. S., et al. (2016) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-16-0196 · Cited by 106 · see citing works

BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function

Yue, X., Zhao, Y., Liu, J., Zhang, C., Yu, H., Wang, J., Zheng, T., Liu, L., Li, J., Feng, Z., et al. (2015) · eLife · doi:10.7554/elife.08401 · Cited by 81 · see citing works

More targets, more pathways and more clues for mutant p53

Garritano, S., Inga, A., Gemignani, F., & Landi, S. (2013) · Oncogenesis · doi:10.1038/oncsis.2013.15 · Cited by 63 · see citing works

Targeting the LKB1 Tumor Suppressor

Zhao, R., & Xu, Z. (2014) · Current Drug Targets · doi:10.2174/1389450114666140106095811 · Cited by 61 · see citing works

The chemosensitivity of testicular germ cell tumors

Voutsadakis, I. A. (2014) · Cellular Oncology · doi:10.1007/s13402-014-0168-6 · Cited by 44 · see citing works

Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code

Ciribilli, Y., Monti, P., Bisio, A., Nguyen, H. T., Ethayathulla, A. S., Ramos, A., Foggetti, G., Menichini, P., Menéndez, D., Resnick, M. A., et al. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt657 · Cited by 43 · see citing works

Tumor suppressor WWOX binds to ΔNp63α and sensitizes cancer cells to chemotherapy

Salah, Z., Bar-Mag, T., Kohn, Y., Pichiorri, F., Palumbo, T., Melino, G., & Aqeilan, R. I. (2013) · Cell Death and Disease · doi:10.1038/cddis.2013.6 · Cited by 41 · see citing works

TAp73 promotes anabolism

Amelio, I., Antonov, A. A., Catani, M. V., Massoud, R., Bernassola, F., Knight, R. A., Melino, G., & Rufini, A. (2014) · Oncotarget · doi:10.18632/oncotarget.2667 · Cited by 40 · see citing works

Preferential Binding of Hot Spot Mutant p53 Proteins to Supercoiled DNA In Vitro and in Cells

Brázdová, M., Navrátilová, L., Tichý, V., Němcová, K., Lexa, M., Hrstka, R., Pečínka, P., Adámik, M., Vojtěšek, B., Paleček, E., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0059567 · Cited by 37 · see citing works

Gene and protein expression of O-GlcNAc-cycling enzymes in human laryngeal cancer

Starska, K., Forma, E., Brzezińska‐Błaszczyk, E., Lewy‐Trenda, I., Bryś, M., Jóźwiak, P., & Krześlak, A. (2014) · Clinical and Experimental Medicine · doi:10.1007/s10238-014-0318-1 · Cited by 33 · see citing works

Molecular dynamics of the full-length p53 monomer

Chillemi, G., Davidovich, P. B., D’Abramo, M., Mametnabiev, T. E., Garabadzhiu, A. V., Desideri, A., & Melino, G. (2013) · Cell Cycle · doi:10.4161/cc.26162 · Cited by 32 · see citing works

Evidence for anti-apoptotic roles of proteasome activator 28γ via inhibiting caspase activity

Moncsek, A., Gruner, M., Meyer, H., Lehmann, A. D., Kloetzel, P., & Stohwasser, R. (2015) · APOPTOSIS · doi:10.1007/s10495-015-1149-6 · Cited by 30 · see citing works

Exploring the molecular aspects associated with testicular germ cell tumors: a review

Facchini, G., Rossetti, S., Cavaliere, C., D’Aniello, C., Franco, R. D., Iovane, G., Grimaldi, G., Piscitelli, R., Muto, P., Botti, G., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.22373 · Cited by 29 · see citing works

Different impacts of TP53 mutations on cell cycle-related gene expression among cancer types

Sasaki, K., Takahashi, S. I., Ouchi, K., Otsuki, Y., Wakayama, S., & Ishioka, C. (2023) · Scientific Reports · doi:10.1038/s41598-023-32092-8 · Cited by 28 · see citing works

A review of gliomas-related proteins. Characteristics of potential biomarkers.

Pienkowski, T., Kowalczyk, T., Kretowski, A. J., & Ciborowski, M. (2021) · PubMed Central · Cited by 25 · see citing works

Context is key: Understanding the regulation, functional control, and activities of the p53 tumour suppressor

Moxley, A. H., & Reisman, D. (2020) · Cell Biochemistry and Function · doi:10.1002/cbf.3590 · Cited by 24 · see citing works

Non-disruptive mutation in TP53 DNA-binding domain is a beneficial factor of esophageal squamous cell carcinoma

Huang, M., Jin, J., Zhang, F., Wu, Y., Xu, C., Ying, L., & Su, D. (2020) · Annals of Translational Medicine · doi:10.21037/atm.2020.02.142 · Cited by 19 · see citing works

The p53 endoplasmic reticulum stress-response pathway evolved in humans but not in mice via PERK-regulated p53 mRNA structures

Fusée, L. T. S., Salomao, N., Ponnuswamy, A., Wang, L., López, I., Chen, S., Gu, X., Polyzoidis, S., Gnanasundram, S. V., & Fåhræus, R. (2023) · Cell Death and Differentiation · doi:10.1038/s41418-023-01127-y · Cited by 18 · see citing works

Association of the MDM2 SNP285 and SNP309 Genetic Variants with the Risk, Age at Onset and Prognosis of Breast Cancer in Central European Women: A Hospital-Based Case-Control Study

Miedl, H., Lebhard, J., Ehart, L., & Schreiber, M. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20030509 · Cited by 14 · see citing works

Loss of LZAP inactivates p53 and regulates sensitivity of cells to DNA damage in a p53-dependent manner

Wamsley, J. J., Gary, C., Biktasova, A., Hajek, M., Bellinger, G., Virk, R. K., Issaeva, N., & Yarbrough, W. G. (2017) · Oncogenesis · doi:10.1038/oncsis.2017.12 · Cited by 15 · see citing works

Constructing a Mouse Oct4 Promoter/EGFP Vector, as a Whole-Cellular Reporter to Monitor the Pluripotent State of Cells.

Ghorbani, R., Emamzadeh, A., Khazaie, Y., Dormiani, K., Ghaedi, K., Rabbani, M., Foruzanfar, M., Karbalaie, K., Karamali, F., Lachinani, L., et al. (2013) · Europe PMC (PubMed Central) · Cited by 11 · see citing works

Suppression of gain-of-function mutant p53 with metabolic inhibitors reduces tumor growthin vivo

Jung, C. L., Mun, H., Jo, S., Oh, J., Lee, C., Choi, E., Jang, S. J., & Suh, Y. (2016) · Oncotarget · doi:10.18632/oncotarget.12758 · Cited by 7 · see citing works

Cancer Genes and Chromosome Instability

Stepanenko, A., & Kavs, V. (2013) · InTech eBooks · doi:10.5772/54017 · Cited by 7 · see citing works

Sequential Treatment with Temozolomide Plus Naturally Derived AT101 as an Alternative Therapeutic Strategy: Insights into Chemoresistance Mechanisms of Surviving Glioblastoma Cells

Hellmold, D., Kubelt, C., Daunke, T., Beckinger, S., Janßen, O., Hauck, M., Schütt, F., Adelung, R., Lucius, R., Haag, J., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24109075 · Cited by 4 · see citing works

Cancer-associated synonymous mutations reveal stress signal-dependent mRNA folding that selectively modulates protein function.

Gnanasundram, S. V., Wang, L., Chen, S., Bonczek, O., Vojtěšek, B., & Fåhræus, R. (2026) · RNA · doi:10.1261/rna.080976.126 · Cited by 1 · see citing works

Prevalence and clinical implications of the TP53 p.R337H mutation in Brazilian breast cancer patients

Costa, E. S. V., Melazzo, I. F., Nogueira, N. A., Abreu, D. C. B., Ayres, F. M., & Saddi, V. A. (2020) · Mastology · doi:10.29289/25945394202020190013 · Cited by 1 · see citing works

Understanding p53 structure and targeting mutant p53 for improved cancer therapy

Zhang, Q. (2018) · Figshare

The role of P53 signaling pathway in aging and cancer

Zhao, Y. (2018) · doi:10.7282/t3-bzph-0b44

The regulation of the p53 isoform p47 following Endoplasmic Reticulum (ER) stress, and physiological implication of single cancer-derived synonymous mutations in initiation of p53 mRNA translation

Fusée, L. T. S. (2020) · doi:10.70675/7d11d779zac70z4ae9zba4bzd0c51b4ce40b

Regulation of cancer redox metabolism by mutant p53

Vargas-Navarro, J. L., Padilla-Flores, J. A., Granados-Rivas, J. C., Aguilar-Torres, L. A., Gregori-Fattel, S. A., Moreno‐Sánchez, R., & Rodríguez‐Enríquez, S. (2026) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2026.107029

The 5th International p63/p73 workshop: much more than just tumour suppression

Kadakia, M., de Fromentel, C. C., & Sabapathy, K. (2012) · Cell Death and Differentiation · doi:10.1038/cdd.2011.204 · Cited by 4 · see citing works

Deconstruction of p53 functions and regulation

Haupt, Y., Robles, A. I., Prives, C. L., & Rotter, V. (2002) · Oncogene · doi:10.1038/sj.onc.1206137 · Cited by 48 · see citing works

Deciphering the significance of p53 mutant proteins

Butera, A., & Amelio, I. (2026) · Trends in Cell Biology · doi:10.1016/j.tcb.2026.01.002

Stimulating p53 down-under: a report from the 1st Australian p53 Workshop

Neilsen, P. M., Braithwaite, A. W., Gamell, C., Haupt, S., Janic, A., Strasser, A., Wolyniec, K., & Haupt, Y. (2013) · Cell Death and Differentiation · doi:10.1038/cdd.2013.2

Proceedings of the p53 Workshop, Trieste, Italy, 1999.

(1999) · PubMed