A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration

Di Stefano, M, Nascimento-Ferreira, I, Orsomando, G, Mori, V, Gilley, J, Brown, R, Janeckova, L, Vargas, M E +15 more·2015·Cell Death & Differentiation
DOI 10.1038/cdd.2014.164

Cited by (250)

Items 101–200 of 250

  1. NMNAT2 supports vesicular glycolysis via NAD homeostasis to fuel fast axonal transport
    Sen Yang, Zhen‐Xian Niou, Andrea Enriquez, Jacob LaMar, Jui-Yen Huang, Karen Ling, Paymaan Jafar‐Nejad, Jonathan Gilley, Michael P. Coleman, Jason M. Tennessen et al. · 2024 · Molecular Neurodegeneration
  2. Nicotinamide Mononucleotide Alleviates Osteoblast Senescence Induction and Promotes Bone Healing in Osteoporotic Mice
    Zufu Lu, Liting Jiang, Pooria Lesani, WenJie Zhang, Ning Li, Danyang Luo, Yusi Li, Yulin Ye, Ji Bian, Guocheng Wang et al. · 2022 · The Journals of Gerontology Series A
  3. Phagocytosis and self-destruction break down dendrites of Drosophila sensory neurons at distinct steps of Wallerian degeneration
    Hui Ji, Maria L. Sapar, Ankita Sarkar, Bei Wang, Chun Han · 2022 · Proceedings of the National Academy of Sciences
  4. SARM1-Dependent Axon Degeneration: Nucleotide Signaling, Neurodegenerative Disorders, Toxicity, and Therapeutic Opportunities
    Helen Ying McGuinness, Weixi Gu, Yun Yu Shi, Boštjan Kobe, Thomas Ve · 2023 · The Neuroscientist
  5. Advancements in NMN biotherapy and research updates in the field of digestive system diseases
    Guanyi Liao, Yuchen Xie, Hong Peng, Tianke Li, Xinsen Zou, Faguo Yue, Jinjun Guo, Li Rong · 2024 · Journal of Translational Medicine
  6. The Axon-Protective WLDS Protein Partially Rescues Mitochondrial Respiration and Glycolysis After Axonal Injury
    Katharina Godzik, M. Coleman · 2014 · Journal of Molecular Neuroscience
  7. Recent Neurotherapeutic Strategies to Promote Healthy Brain Aging: Are we there yet?
    Chul-Kyu Kim, P. Sachdev, N. Braidy · 2022 · Aging and Disease
  8. Nicotinamide Mononucleotide Supplementation: Understanding Metabolic Variability and Clinical Implications
    Candace Benjamin, Rebecca Crews · 2024 · Metabolites
  9. Complex role of nicotinamide adenine dinucleotide in the regulation of programmed cell death pathways
    Nicolas Preyat, Oberdan Léo · 2015 · Biochemical Pharmacology
  10. Oral nicotinamide provides robust, dose-dependent structural and metabolic neuroprotection of retinal ganglion cells in experimental glaucoma
    Gloria Cimaglia, James R. Tribble, Marcela Votruba, Pete A. Williams, James E. Morgan · 2024 · Acta Neuropathologica Communications
  11. Brain Trauma and the Secondary Cascade in Humans: Review of the Potential Role of Vitamins in Reparative Processes and Functional Outcome
    Rebecca J. Denniss, Lynne Ann Barker · 2023 · Behavioral Sciences
  12. Corneal Denervation Causes Epithelial Apoptosis Through Inhibiting NAD + Biosynthesis
    Ya Li, Xiubin Ma, Jing Li, Lingling Yang, Xiaowen Zhao, Xia Qi, Xiaoping Zhang, Qingjun Zhou, Weiyun Shi · 2019 · Investigative Ophthalmology & Visual Science
  13. Increased ROS Level in Spinal Cord of Wobbler Mice due to Nmnat2 Downregulation
    Pascal Röderer, Lara Klatt, Felix John, Verena Theis, Konstanze F. Winklhofer, Carsten Theiß, Veronika Matschke · 2018 · Molecular Neurobiology
  14. The influence of BACE1 on macrophage recruitment and activity in the injured peripheral nerve
    John A. Fissel, Mohamed H. Farah · 2021 · Journal of Neuroinflammation
  15. An atypical ubiquitin ligase at the heart of neural development and programmed axon degeneration
    Satpal Virdee · 2022 · Neural Regeneration Research
  16. NAD + , Axonal Maintenance, and Neurological Disease
    Athanasios S. Alexandris, Vassilis E. Koliatsos · 2023 · Antioxidants and Redox Signaling
  17. Molecular mechanisms in the initiation phase of Wallerian degeneration
    Biao Chang, Qi Quan, Shibi Lu, Yu Wang, Jiang Peng · 2016 · European Journal of Neuroscience
  18. Development of abnormalities at the neuromuscular junction in the SOD1-G93A mouse model of ALS: dysfunction then disruption of postsynaptic structure precede overt motor symptoms
    Jayne McIntosh, Imane Mekrouda, Maryam Dashti, Claudiu V. Giuraniuc, Robert W. Banks, Gareth Brian Miles, Guy S. Bewick · 2023 · Frontiers in Molecular Neuroscience
  19. Discovery of a novel NAMPT inhibitor that selectively targets NAPRT-deficient EMT-subtype cancer cells and alleviates chemotherapy-induced peripheral neuropathy
    Min‐Jee Kim, Hyeyoung Kim, Bu-Gyeong Kang, Joo‐Young Lee, Taegun Kim, Hwanho Lee, Jane Jung, Myung Joon Oh, Seungyoon Seo, Myung‐Jeom Ryu et al. · 2023 · Theranostics
  20. Caffeine and NAD+ Improve Motor Neural Integrity of Dissociated Wobbler Cells In Vitro
    Mareike Zwilling, Carsten Theiß, Veronika Matschke · 2020 · Antioxidants
  21. Neurotoxin-mediated --potent activation of the axon degeneration regulator SARM1.
    Andrea Loreto, Angeletti, Carlo, Weixi Gu, Andrew Osborne, Bart Nieuwenhuis, Jonathan Gilley, Elisa Merlini, Peter Arthur‐Farraj, Adolfo Amici, Zhenyao Luo et al. · 2021 · Apollo (University of Cambridge)
  22. Augustus Waller’s foresight realized: SARM1 in peripheral neuropathies
    Stefanie Geisler · 2024 · Current Opinion in Neurobiology
  23. Quantitation of NAD+: Why do we need to measure it?
    Yue Liu, James Clement, Ross Grant, Perminder Singh Sachdev, Nady Braidy · 2018 · Biochimica et Biophysica Acta (BBA) - General Subjects
  24. A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria
    Konstantin Feinberg, Adelaida Kolaj, Chen Wu, Natalie Grinshtein, Jonathan R. Krieger, Michael F. Moran, Lee L. Rubin, Freda D. Miller, David R. Kaplan · 2017 · The Journal of Cell Biology
  25. The SARM1 TIR NADase: Mechanistic Similarities to Bacterial Phage Defense and Toxin-Antitoxin Systems
    Aaron DiAntonio, Jeffrey Milbrandt, Matthew D. Figley · 2021 · Frontiers in Immunology
  26. A conformation-specific nanobody targeting the nicotinamide mononucleotide-activated state of SARM1
    Yun Nan Hou, Yang Cai, Wan Hua Li, Wei He, Zhi Ying Zhao, Wenjie Zhu, Qiang Wang, Xinyi Mai, Jun Liu, Hon Cheung Lee et al. · 2022 · Nature Communications
  27. Application of virtual screening to the discovery of novel nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with potential for the treatment of cancer and axonopathies
    David E. Clark, Bohdan Waszkowycz, Melanie H.L. Wong, Peter M. Lockey, Róbert Adalbert, Jonathan Gilley, Jonathan P. Clark, Michael P. Coleman · 2016 · Bioorganic & Medicinal Chemistry Letters
  28. Acute exercise boosts NAD+ metabolism of human peripheral blood mononuclear cells
    David Walzik, Niklas Joisten, Alexander Schenk, Sina Trebing, Kirill Schaaf, Alan J. Metcalfe, Polyxeni Spiliopoulou, Johanna Hiefner, Adrian McCann, Carsten Watzl et al. · 2024 · Brain Behavior and Immunity
  29. SIRT1-dependent restoration of NAD+ homeostasis after increased extracellular NAD+ exposure
    Daniela Buonvicino, Giuseppe Ranieri, Maria Gloria Pittelli, Andrea Lapucci, Stefania Bragliola, Alberto Chiarugi · 2021 · Journal of Biological Chemistry
  30. Glaucoma: neuroprotection with NAD-based therapeutic interventions
    Alberto Chiarugi · 2023 · Trends in Pharmacological Sciences
  31. The SARM1 TIR domain produces glycocyclic ADPR molecules as minor products
    Jeremy Garb, Gil Amitai, Allen Lu, Gal Ofir, Alexander S. Brandis, Tevie Mehlman, Philip J. Kranzusch, Rotem Sorek · 2024 · PLoS ONE
  32. Deletion of CD38 and supplementation of NAD+ attenuate axon degeneration in a mouse facial nerve axotomy model
    Takaso, Yuji, Noda, Masao, Hattori, Tsuyoshi, Roboon, Jureepon, Hatano, Miyako, Sugimoto, Hisashi, Brenner, Charles, Yamamoto, Yasuhiko, Okamoto, Hiroshi, Higashida, Haruhiro et al. · 2020 · Scientific Reports
  33. Protective effects of NAMPT or MAPK inhibitors and NaR on Wallerian degeneration of mammalian axons
    Athanasios S. Alexandris, Jiwon Ryu, Labchan Rajbhandari, Robert Harlan, James McKenney, Yiqing Wang, Susan M. Aja, David R. M. Graham, Arun Venkatesan, Vassilis E. Koliatsos · 2022 · Neurobiology of Disease
  34. Zebrafish cutaneous injury models reveal that Langerhans cells engulf axonal debris in adult epidermis
    Eric Peterman, Elgene J. A. Quitevis, Erik C. Black, Emma C. Horton, Rune L. Aelmore, Ethan White, Alvaro Sagasti, Jeffrey P. Rasmussen · 2023 · Disease Models & Mechanisms
  35. Short-term diabetic hyperglycemia suppresses celiac ganglia neurotransmission, thereby impairing sympathetically mediated glucagon responses
    Thomas O. Mundinger, Ellis Cooper, Michael P. Coleman, Gerald J. Taborsky · 2015 · American Journal of Physiology-Endocrinology and Metabolism
  36. SARM1 can be a potential therapeutic target for spinal cord injury
    Qicheng Lu, Benson O. A. Botchway, Yong Zhang, Tian Jin, Xuehong Liu · 2022 · Cellular and Molecular Life Sciences
  37. Simultaneous quantification of nicotinamide mononucleotide and related pyridine compounds in mouse tissues by UHPLC–MS/MS
    Francesco M. Carpi, Manuela Cortese, Giuseppe Orsomando, Valeria Polzonetti, Silvia Vincenzetti, Benedetta Moreschini, Michael P. Coleman, Giulio Magni, Stefania Pucciarelli · 2018 · Separation Science Plus
  38. Progressive axonopathy when oligodendrocytes lack the myelin protein CMTM5
    Buscham, Tobias J, Eichel-Vogel, Maria A, Steyer, Anna M, Jahn, Olaf, Strenzke, Nicola, Dardawal, Rakshit, Memhave, Tor R, Siems, Sophie B, Müller, Christina, Meschkat, Martin et al. · 2022 · eLife
  39. NAD+ metabolism in peripheral neuropathic pain
    Yi Dai, Jiaqi Lin, Jinxuan Ren, Bin Zhu, Chengwei Wu, Lina Yu · 2022 · Neurochemistry International
  40. Therapeutic Effect of Nicotinamide Mononucleotide for Hypoxic–Ischemic Brain Injury in Neonatal Mice
    Takuya Kawamura, Gagandeep Singh‐Mallah, Maryam Ardalan, Tetyana Chumak, Pernilla Svedin, Lina Jönsson, Seyedeh Marziyeh Jabbari Shiadeh, Fanny Goretta, Tomoaki Ikeda, Henrik Hagberg et al. · 2023 · ASN NEURO
  41. Loss of highwire Protects Against the Deleterious Effects of Traumatic Brain Injury in Drosophila Melanogaster
    C. Hill, Jemeen Sreedharan, A. Loreto, D. Menon, M. Coleman · 2020 · Frontiers in Neurology
  42. SARM1 Depletion Slows Axon Degeneration in a CNS Model of Neurotropic Viral Infection
    Colin L. Crawford, Christina Antoniou, Lina Komarek, Verena Schultz, Claire L. Donald, Paul Montague, Susan Carol Barnett, Christopher Linington, Hugh John Willison, Alain Kohl et al. · 2022 · Frontiers in Molecular Neuroscience
  43. Activity-dependent degeneration of axotomized neuromuscular synapses in WldS mice
    Rosalind Brown, Antony M. Hynes-Allen, Amanda Swan, Kosala N. Dissanayake, Thomas Henry Gillingwater, Richard R. Ribchester · 2015 · Neuroscience
  44. SARM1 activation induces reversible mitochondrial dysfunction and can be prevented in human neurons by antisense oligonucleotides
    Andrea Loreto, Kaitlyn M. L. Cramb, Lucy McDermott, Christina Antoniou, Ilenia Cirilli, Maria Claudia Caiazza, Elisa Merlini, Peter Arthur‐Farraj, Willem Daniel du Preez, Elliot D. Mock et al. · 2025 · Neurobiology of Disease
  45. Die in pieces: How Drosophila sheds light on neurite degeneration and clearance
    Maria L. Sapar, Chun Han · 2019 · Journal of genetics and genomics/Journal of Genetics and Genomics
  46. SARM1 activation promotes axonal degeneration via a two-step phase transition
    Wenbin Zhang, Qinyi Zhou, Jun Zhang, Jiachen Wang, Qingcui Wu, Sanduo Zheng, Xiaodong Wang · 2025 · Nature Chemical Biology
  47. Alpha-synucleinopathy reduces NMNAT3 protein levels and neurite formation that can be rescued by targeting the NAD+ pathway
    Richard B. Parsons, Altin Kocinaj, Gustavo Ruiz-Pulido, Sarah A Prendergast, Anna E. Parsons, Paul D. Facey, Frank Hirth · 2022 · Human Molecular Genetics
  48. Nicotinamide mononucleotide (NMN) ameliorated Nonylphenol-induced learning and memory impairment in rats via the central 5-HT system and the NAD+/SIRT1/MAO-A pathway
    Huiying Huang, Jian Shi, Zhongyi Li, Yifeng Rang, Weiye Li, Xueman Xiao, Congying Chen, Chunhong Liu · 2023 · Food and Chemical Toxicology
  49. SARM1 is responsible for calpain-dependent dendrite degeneration in mouse hippocampal neurons
    Takashi Miyamoto, Chaeyoung Kim, Johann Chow, Jason C. Dugas, Jack DeGroot, Alex L. Bagdasarian, Arun P. Thottumkara, Martin Larhammar, Meredith Calvert, Brian M. Fox et al. · 2024 · Journal of Biological Chemistry
  50. NAD+ Anabolism Disturbance Causes Glomerular Mesangial Cell Injury in Diabetic Nephropathy
    Li, Xue, Li, Yankun, Li, Fengxia, Chen, Qi, Zhao, Zhonghua, Liu, Xueguang, Zhang, Nong, Li, Hui · 2022 · International Journal of Molecular Sciences
  51. NMN Alleviates NP-Induced Learning and Memory Impairment Through SIRT1 Pathway in PC-12 Cell
    Zhongyi Li, Huan Liu, Wenna Han, Siyu Zhu, Chunhong Liu · 2023 · Molecular Neurobiology
  52. Risks and rewards of targeting NAD+ homeostasis in the brain
    Catherine Li, Lindsay E. Wu · 2021 · Mechanisms of Ageing and Development
  53. Improving Mitochondrial Function in Skeletal Muscle Contributes to the Amelioration of Insulin Resistance by Nicotinamide Riboside
    Qiuyan Li, Xuye Jiang, Yujia Zhou, Yingying Gu, Yijie Ding, Jing Luo, Nengzhi Pang, Yan Sun, Lei Pei, Jie Pan et al. · 2023 · International Journal of Molecular Sciences
  54. Nicotinamide Adenine Dinucleotide (NAD + )-Dependent Signaling in Neurological Disorders
    Mariana Bresque, Daniel Esteve, Mariana Pehar, Marcelo R. Vargas · 2023 · Antioxidants and Redox Signaling
  55. Human serine racemase is allosterically modulated by NADH and reduced nicotinamide derivatives
    Stefano Bruno, Francesco Marchesani, Luca Dellafiora, Marilena Margiotta, Serena Faggiano, Barbara Campanini, Andrea Mozzarelli · 2016 · Biochemical Journal
  56. Neurophysiological functions and pharmacological tools of acidic and non-acidic Ca2+ stores
    Lora L. Martucci, José‐Manuel Cancela · 2022 · Cell Calcium
  57. SARM1 senses dsDNA to promote NAD+ degradation and cell death
    Lina Wang, Qiaoling Liu, Siru Li, Na Wang, Yan Chen, Junren Chen, Li Wang, Yuelin Huang, Zhen Sun, Ling Dong et al. · 2025 · Cell
  58. Natural variants of human SARM1 cause both intrinsic and dominant loss-of-function influencing axon survival
    Mirlinda Ademi, Xiuna Yang, Michael P. Coleman, Jonathan Gilley · 2022 · Scientific Reports
  59. Programmed axon death: a promising target for treating retinal and optic nerve disorders
    Andrea Loreto, Elisa Merlini, Michael P. Coleman · 2024 · Eye
  60. NAD+-dependent mechanism of pathological axon degeneration
    Ying Cao, Yi Wang, Jing Hui Yang · 2022 · Cell Insight
  61. Mitophagy suppresses motor neuron necroptotic mitochondrial damage and alleviates necroptosis that converges to SARM1 in acrylamide‐induced dying‐back neuropathy
    Shuai Wang, Yiyu Yang, Zhigang Yu, Mingxue Song, Z. Q. Liu, Shulin Shan, Hui Yong, Wenting Ni, Yalong Qiang, Cuiqin Zhang et al. · 2023 · Journal of Neurochemistry
  62. Exploring the Role of Axons in ALS from Multiple Perspectives
    Xiaosu Chen, Shujun Lv, Jinmeng Liu, Yingjun Guan, Chunjie Xu, Xiaonan Ma, Mu Li, Xue Bai, Kexin Liu, Haoyun Zhang et al. · 2024 · Cells
  63. SARM1 Activation Promotes Axonal Degeneration Via a Two-Step Liquid-to-Solid Phase Transition
    Zhang Wenbin, Zhou Qinyi, Jun Zhang, Jiachen Wang, Sanduo Zheng, Xiaodong Wang · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  64. Loss of SARM1 ameliorates secondary thalamic neurodegeneration after cerebral infarction
    Kun Zhou, Yan Zhi Tan, Guofen Zhang, Jingjing Li, Shihui Xing, Xinran Chen, Jiali Wen, Ge Li, Yuhua Fan, Jinsheng Zeng et al. · 2023 · Journal of Cerebral Blood Flow & Metabolism
  65. Quantitative dynamics of intracellular NMN by genetically encoded biosensor
    Liuqing Chen, Pei Wang, Guan Huang, Wenxiang Cheng, Kaijing Liu, Qiuliyang Yu · 2024 · Biosensors and Bioelectronics
  66. Axon Degeneration Assays in Superior Cervical Ganglion Explant Cultures
    Andrea Loreto, Jonathan Gilley · 2020 · Methods in molecular biology
  67. Salvage NAD+ biosynthetic pathway enzymes moonlight as molecular chaperones to protect against proteotoxicity
    Meredith Pinkerton, Andrea Ruetenik, Viktoriia Bazylianska, Eva Nývltová, Antoni Barrientos · 2021 · Human Molecular Genetics
  68. NAD+ metabolism and eye diseases: current status and future directions
    Siyuan Liu, Wenfang Zhang · 2023 · Molecular Biology Reports
  69. Programmed axon degeneration: mechanism, inhibition and therapeutic potential
    Andrea Loreto, Lukas Jakob Neukomm · 2025 · Nature reviews. Neuroscience
  70. Role of NAD+ and FAD in Ischemic Stroke Pathophysiology: An Epigenetic Nexus and Expanding Therapeutic Repertoire
    Parimala Narne, Prakash Babu Phanithi · 2022 · Cellular and Molecular Neurobiology
  71. Ex Vivo Integration of Human Stem Retinal Ganglion Cells into the Mouse Retina
    Louis‐Philippe Croteau, Michael L. Risner, Lauren Katie Wareham, Nolan R. McGrady, Xitiz Chamling, Donald J. Zack, David John Calkins · 2022 · Cells
  72. The Molecular Mechanisms Involved in Axonal Degeneration and Retrograde Retinal Ganglion Cell Death
    Zhaoyang Zuo, Zi-Yuan Zhang, Si‐Ming Zhang, Bin Fan, Guangyu Li · 2023 · DNA and Cell Biology
  73. Boosting NAD to Spare Hearing
    Charles Brenner · 2014 · Cell Metabolism
  74. Pivotal Roles for Membrane Phospholipids in Axonal Degeneration.
    Mohammadali Almasieh, Hannah Faris, L. Levin · 2022 · International Journal of Biochemistry and Cell Biology
  75. Regulation of degenerative spheroids after injury
    Yong Yu, Kanchana K. Gamage, Courtny Cushman, Anthony Spano, Christopher D. Deppmann · 2020 · Scientific Reports
  76. NAD+ Precursors Reverse Experimental Diabetic Neuropathy in Mice
    Krish Chandrasekaran, Neda Najimi, Avinash Rao Sagi, Sushuma Yarlagadda, Mohammad Salimian, Muhammed Ikbal Arvas, Ahmad F. Hedayat, Yanni Kevas, Anand Kadakia, Tibor Kristián et al. · 2024 · International Journal of Molecular Sciences
  77. Research advances in the function and anti-aging effects of nicotinamide mononucleotide
    Min Wang, Yuan Cao, Yun Li, Lu Wang, Yuyan Liu, Zihui Deng, Lianrong Zhu, Hongjun Kang · 2024 · Journal of Zhejiang University SCIENCE B
  78. Targeting SARM1: from inhibition for neuroprotection to activation for neuroablation
    Peter Arthur‐Farraj, Andrea Loreto · 2025 · Trends in Pharmacological Sciences
  79. Biotechnological production of reduced and oxidized NAD+ precursors
    Ruben Zapata Perez, Antonio Ginés García-Saura, Angelique M. L. Scantlebery, Bauke V. Schomakers, Rubén Rabadán-Ros, Michel van Weeghel, Riekelt H. Houtkooper, Álvaro Sánchez‐Ferrer · 2023 · Food Research International
  80. Preparation of Viable Human Neurites for Neurobiological and Neurodegeneration Studies
    Markus Brüll, Nils Geese, Ivana Celardo, Michael Laumann, Marcel Leist · 2024 · Cells
  81. P7C3-A20 neuroprotection is independent of Wallerian degeneration in primary neuronal culture
    Ciaran Scott Hill, David Krishna Menon, Michael P. Coleman · 2018 · Neuroreport
  82. Neuronal NMNAT2 Overexpression Does Not Achieve Significant Neuroprotection in Experimental Autoimmune Encephalomyelitis/Optic Neuritis
    Pingting Liu, Haoliang Huang, Fang Fang, Liang Liu, Liang Li, Xue Feng, Wei Chen, Roopa Dalal, Yang Sun, Yang Hu · 2021 · Frontiers in Cellular Neuroscience
  83. Differences in Extracellular NAD+ and NMN Metabolism on the Surface of Vascular Endothelial Cells
    Patrycja Jabłońska, Paulina Mierzejewska, Marta Tomczyk, Patrycja Koszałka, Marika Frańczak, Ada Kawecka, Barbara Anna Kutryb-Zając, Alicja Braczko, Ryszard Tomasz Smolenski, Ewa Maria Slominska · 2022 · Biology
  84. Gap junction intercellular communications regulates activation of SARM1 and protects against axonal degeneration
    Wenjie Zhu, Jun Liu, Wan Hua Li, Zhi Ying Zhao, Chongquan Huang, Jian Yuan Yang, Hon Cheung Lee, Yong Juan Zhao · 2025 · Cell Death and Disease
  85. The Physiologic Basis of Molecular Therapeutics for Peripheral Nerve Injury: A Primer
    Marie C. Spezia, Christopher J. Dy, David M. Brogan · 2024 · Journal of Hand Surgery Global Online
  86. A phase transition reduces the threshold for nicotinamide mononucleotide-based activation of SARM1, an NAD(P) hydrolase, to physiologically relevant levels
    Janneke D. Icso, Paul R. Thompson · 2023 · Journal of Biological Chemistry
  87. Avian axons undergo Wallerian degeneration after injury and stress
    J. Bramley, S. Collins, Karen B. Clark, W. Buchser · 2016 · Journal of Comparative Physiology
  88. Connexins and blood-brain barrier: Beyond the gap
    Audrey Chagnot, Axel Montagne · 2023 · Neuron
  89. Characterization of Two NMN Deamidase Mutants as Possible Probes for an NMN Biosensor
    Alessandra Camarca, Gabriele Minazzato, Angela Pennacchio, Alessandro Capo, Adolfo Amici, Sabato D’Auria, Nadia Raffaelli · 2021 · International Journal of Molecular Sciences
  90. Microinjection of Superior Cervical Ganglion Neurons for Studying Axon Degeneration
    Jonathan Gilley, Andrea Loreto · 2020 · Methods in molecular biology
  91. CD38-NAD(+) Axis: New Insights into Glaucoma Therapy
    Wenyige Zhang, Haina Zheng, Yulian Pang, Yujia Wang, Xu Zhang · 2025 · Molecular Neurobiology
  92. The rise and fall of SARM1 base-exchange inhibitors
    Thomas Lundbäck, Vijay Chandrasekar, Chendi Gu, Hyoungseok Ju, Robyn L. McAdam, Maria Palomero, Kasim Sader, Bradley Peter, Lisa Wissler, Philip Nevin et al. · 2026 · Communications Chemistry
  93. Comparison of anti-aging effect of PQQ (Pyrroloquinoline quinone) and NMN/NR (Nicotinamide mononucleotide /Nicotinamide riboside) – possible combination use
    Savani Ulpathakumbura, Sicong Lu, Rasika Gunarathne, John Zhiyong Yang, Johnson Liu, Xiaodong Jin, Qiang Zhou, Jun Lu · 2025 · Ageing Research Reviews
  94. Crystal structure determination of the armadillo repeat domain of Drosophila SARM1 using MIRAS phasing
    Weixi Gu, Zhenyao Luo, Clemens Vonrhein, Xinying Jia, Thomas Ve, Jeffrey D. Nanson, Boštjan Kobe · 2021 · Acta Crystallographica Section F Structural Biology Communications
  95. Glycolytic System in Axons Supplement Decreased ATP Levels after Axotomy of the Peripheral Nerve
    Tomofumi TAKENAKA, Yu‐ichiro Ohnishi, Masamichi Yamamoto, Daiki Setoyama, Haruhiko Kishima · 2023 · eNeuro
  96. Nicotinamide Adenine Dinucleotide Precursor Supplementation Modulates Neurite Complexity and Survival in Motor Neurons from Amyotrophic Lateral Sclerosis Models
    Haylee L. Hamilton, Mahbuba Akther, S. Anis, Christopher B. Colwell, Marcelo R. Vargas, Mariana Pehar · 2024 · Antioxidants and Redox Signaling
  97. NMNAT2 in cortical glutamatergic neurons exerts both cell and non-cell autonomous influences to shape cortical development and to maintain neuronal health
    Zhen‐Xian Niou, Sen Yang, Anoosha Sri, Hugo Rodriquez, Jonathan Gilley, Michael P. Coleman, Hui‐Chen Lu · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  98. Programmed neurite degeneration in human central nervous system neurons driven by changes in NAD+ metabolism
    Markus Brüll, Selina Multrus, Michael Schäfer, Ivana Celardo, Christiaan Karreman, Marcel Leist · 2025 · Cell Death and Disease
  99. Sodium dehydroacetate induces porcine oocyte toxicity by inhibiting TCA cycle activity and mitochondrial function, with nicotinamide mononucleotide as a potential protective agent
    Na Li, Yu Li, Guangjun Huang, Hongyu Sun, Jiaqi Wu, Qian Gao, Zhaokang Cui, Yilong Miao · 2025 · Food and Chemical Toxicology
  100. High cell density continuous production of nicotinamide mononucleotide by metabolically engineered Escherichia coli
    Giang Thi Thu Vo, Beom Soo Kim · 2025 · Chemical Engineering Science