The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Implications of Obesity for Drug Therapy: Limitations and Challenges
Abstract
Obesity has become a worldwide challenge with significant health and socioeconomic implications. One of the major implications is its impact on drug therapy. In order to gain a better understanding of this impact, we surveyed the regulatory guidances, the newly approved molecular entity drug products, and drug product labels in the Physician's Desk Reference. This review summarizes the findings of the survey along with the existing knowledge on pharmacokinetic and pharmacodynamic changes associated with obesity.
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Citations
Cites
Anthropometric Reference Data for Children and Adults: United States, 2003-2006: (623932009-001)
McDowell, M. A., Fryar, C. D., Ogden, C. L., & Flegal, K. M. (2008) · PsycEXTRA Dataset · doi:10.1037/e623932009-001 · Cited by 1,378
Functional and Structural Changes in the Kidney in the Early Stages of Obesity
HENEGAR, J. R., BIGLER, S. A., HENEGAR, L. K., TYAGI, S. C., & HALL, J. E. (2001) · Journal of the American Society of Nephrology · doi:10.1681/asn.v1261211 · Cited by 549
Sudden cardiac arrest in morbidly obese surgical patients unexplained after autopsy
Drenick, E. J., & Fisler, J. S. (1988) · The American Journal of Surgery · doi:10.1016/s0002-9610(88)80029-1 · Cited by 107
Cited by
Obesity and the risk and outcome of infection
Huttunen, R., & Syrjänen, J. (2013) · International Journal of Obesity · doi:10.1038/ijo.2012.62 · Cited by 594
The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection
Mazuski, J. E., Tessier, J. M., May, A. K., Sawyer, R. G., Nadler, E. P., Rosengart, M. R., Chang, P. K., O'Neill, P. J., Mollen, K. P., Huston, J. M., et al. (2017) · Surgical Infections · doi:10.1089/sur.2016.261 · Cited by 573
Adipocyte and lipid metabolism in cancer drug resistance
Cao, Y. (2019) · Journal of Clinical Investigation · doi:10.1172/jci127201 · Cited by 522
Impact of Obesity on Drug Metabolism and Elimination in Adults and Children
Brill, M. J. E., Diepstraten, J., van Rongen, A., van Kralingen, S., van den Anker, J. N., & Knibbe, C. A. J. (2012) · Clinical Pharmacokinetics · doi:10.2165/11599410-000000000-00000 · Cited by 382
Metadata
- Authors
- Jain, R., Chung, S. M., Jain, L., Khurana, M., Lau, S. W. J., Lee, J. E., Vaidyanathan, J., Zadezensky, I., Choe, S., & Sahajwalla, C. G.
- Venue
- Clinical Pharmacology & Therapeutics
- Publisher
- Wiley
- Published
- 2011-06-01
- Volume
- 90
- Issue
- 1
- Pages
- 77-89
- ISSN
- 0009-9236 (ISSN-L)
- 1532-6535
- OpenAlex
- W2060709791
- Cited by
- 210
- References
- 3
- FWCI
- 8.76
- Type
- journal article
- Language
- en
- Open access
- closed
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- Jain, R., Chung, S. M., Jain, L., Khurana, M., Lau, S. W. J., Lee, J. E., Vaidyanathan, J., Zadezensky, I., Choe, S., & Sahajwalla, C. G. (2011). Implications of Obesity for Drug Therapy: Limitations and Challenges. Clinical Pharmacology & Therapeutics. https://doi.org/10.1038/clpt.2011.104
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
