The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Ski and SnoN, potent negative regulators of TGF-β signaling
Open accessAbstract
Ski and the closely related SnoN were discovered as oncogenes by their ability to transform chicken embryo fibroblasts upon overexpression. While elevated expressions of Ski and SnoN have also been reported in many human cancer cells and tissues, consistent with their pro-oncogenic activity, emerging evidence also suggests a potential anti-oncogenic activity for both. In addition, Ski and SnoN have been implicated in regulation of cell differentiation, especially in the muscle and neuronal lineages. Multiple cellular partners of Ski and SnoN have been identified in an effort to understand the molecular mechanisms underlying the complex roles of Ski and SnoN. In this review, we summarize recent findings on the biological functions of Ski and SnoN, their mechanisms of action and how their levels of expression are regulated.
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Cites
The Ski protein family is required for MeCP2-mediated transcriptional repression.
Kokura, K., Kaul, S. C., Wadhwa, R., Nomura, T., Khan, M. M., Shinagawa, T., Yasukawa, T., Colmenares, C., & Ishii, S. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105747200 · Cited by 222
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EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
Shibue, T., & Weinberg, R. A. (2017) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2017.44 · Cited by 2,539
Specificity, versatility, and control of TGF-β family signaling
Derynck, R., & Budi, E. H. (2019) · Science Signaling · doi:10.1126/scisignal.aav5183 · Cited by 785
TGF-β Family Signaling in the Control of Cell Proliferation and Survival
Zhang, Y., Alexander, P. B., & Wang, X.-F. (2017) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a022145 · Cited by 626
The TGFbeta Superfamily Signaling Pathway
Weiss, A., & Attisano, L. (2013) · WIREs Developmental Biology · doi:10.1002/wdev.86 · Cited by 561
Transcriptional Control by the SMADs
Hill, C. S. (2016) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a022079 · Cited by 351
Metadata
- Authors
- Deheuninck, J., & Luo, K.
- Venue
- Cell Research
- Published
- 2008-12-30
- Volume
- 19
- Issue
- 1
- Pages
- 47-57
- ISSN
- 1001-0602 (ISSN-L)
- 1748-7838
- OpenAlex
- W1971093570
- Cited by
- 257
- References
- 1
- FWCI
- 5.34
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Deheuninck, J., & Luo, K. (2009). Ski and SnoN, potent negative regulators of TGF-β signaling. Cell Research. https://doi.org/10.1038/cr.2008.324
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
