Autophagy‐based unconventional secretory pathway for extracellular delivery of IL‐1β

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Items 301–400 of 967

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  3. NLRP3 inflammasome in cardiovascular diseases: Pathophysiological and pharmacological implications
    Carolina Pellegrini, Alma Martelli, Luca Antonioli, Matteo Fornai, Corrado Blandizzi, Vincenzo Calderone · 2021 · Medicinal Research Reviews
  4. Secretory autophagy-induced bladder tumour-derived extracellular vesicle secretion promotes angiogenesis by activating the TPX2-mediated phosphorylation of the AURKA-PI3K-AKT axis
    Xinyuan Li, Zongjie Wei, Haitao Yu, Yingjie Xu, Weiyang He, Xiang Zhou, Xin Gou · 2021 · Cancer Letters
  5. Regulation Where Autophagy Intersects the Inflammasome
    Mary A. Rodgers, James W. Bowman, Qiming Liang, Jae Ung Jung · 2013 · Antioxidants and Redox Signaling
  6. Proteomic and Bioinformatic Characterization of Extracellular Vesicles Released from Human Macrophages upon Influenza A Virus Infection
    Wojciech Cypryk, Martina B. Lorey, Anne Puustinen, Tuula A. Nyman, Sampsa Matikainen · 2016 · Journal of Proteome Research
  7. Autophagy and the endo/exosomal pathways in health and disease
    Margarita‐Elena Papandreou, Nektarios Tavernarakis · 2016 · Biotechnology Journal
  8. Autophagy Protects Against Developing Increased Lung Permeability and Hypoxemia by Down Regulating Inflammasome Activity and IL-1β in LPS Plus Mechanical Ventilation-Induced Acute Lung Injury
    Nobuyuki Nosaka, Daisy Martinon, Debbie Moreira, Timothy R. Crother, Moshe Arditi, Kenichi Shimada · 2020 · Frontiers in Immunology
  9. Atg8ylation as a general membrane stress and remodeling response
    Suresh G. Kumar, Jingyue Jia, Vojo P. Deretic · 2021 · Cell Stress
  10. Biological Functions and Therapeutic Potential of Autophagy in Spinal Cord Injury
    Hai-Yang Liao, Zhi-Qiang Wang, Rui Ran, Kai‐Sheng Zhou, Chun-Wei Ma, Haihong Zhang · 2021 · Frontiers in Cell and Developmental Biology
  11. New insights into autophagy in hepatocellular carcinoma: mechanisms and therapeutic strategies.
    Shuo Yang, Liang Yang, Xinyu Li, Bowen Li, Yan Li, Xiaodong Zhang, Yingbo Ma, Xueqiang Peng, Hongyuan Jin, Hangyu Li · 2019 · PubMed Central
  12. Inhibition of endolysosome fusion increases exosome secretion
    Ganesh Vilas Shelke, Chad D. Williamson, Michal Jarník, Juan S. Bonifacino · 2023 · The Journal of Cell Biology
  13. The Journey of the Autophagosome through Mammalian Cell Organelles and Membranes
    Diana Molino, Naïma Zemirli, Patrice Codogno, Étienne Morel · 2016 · Journal of Molecular Biology
  14. How Autophagy Shapes the Tumor Microenvironment in Ovarian Cancer
    Alessandra Ferraresi, Carlo Girone, Andrea Esposito, Chiara Vidoni, Letizia Vallino, Eleonora Secomandi, Danny N. Dhanasekaran, Ciro Isidoro · 2020 · Frontiers in Oncology
  15. 14,15-Epoxyeicosatrienoic acid suppresses cigarette smoke condensate-induced inflammation in lung epithelial cells by inhibiting autophagy
    Yunxiao Li, Ganggang Yu, Shaopeng Yuan, Chunting Tan, Jianlin Xie, Yasi Ding, Puqiao Lian, Lixia Fu, Qi Hou, Bo Xu et al. · 2016 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  16. A Mechanism Coupling Systemic Energy Sensing to Adipokine Secretion
    Akhila Rajan, Benjamin E. Housden, Frederik Wirtz‐Peitz, Laura Holderbaum, Norbert Perrimon · 2017 · Developmental Cell
  17. Autophagy’s secret life: secretion instead of degradation
    Aurore Claude‐Taupin, Jingyue Jia, Michal H. Mudd, Vojo P. Deretic · 2017 · Essays in Biochemistry
  18. Impact of Autophagy of Innate Immune Cells on Inflammatory Bowel Disease
    Tomoya Iida, Yoshihiro Yokoyama, Kohei Wagatsuma, Daisuke Hirayama, Hiroshi Nakase · 2018 · Cells
  19. GRASP55 and UPR Control Interleukin-1β Aggregation and Secretion.
    M. Chirițoiu, N. Brouwers, Gabriele Turacchio, Marinella Pirozzi, V. Malhotra · 2019 · Developmental Cell
  20. Exosomes, autophagy and ER stress pathways in human diseases: Cross-regulation and therapeutic approaches
    Babak Jahangiri, Ali Kian Saei, Patience O. Obi, Narjes Asghari, Shahrokh Lorzadeh, Shirin Hekmatirad, Marveh Rahmati, Fatemeh Velayatipour, Mohammad Hosseni Asghari, Ayesha Saleem et al. · 2022 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  21. Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation
    Sunmin Park, Michael D. Buck, Chandni Desai, Xin Zhang, Ekaterina Loginicheva, Jennifer Martinez, Michael L. Freeman, Tatsuya Saitoh, Shizuo Akira, Jun‐Lin Guan et al. · 2016 · Cell Host & Microbe
  22. Calpain Activity Is Essential for ATP-Driven Unconventional Vesicle-Mediated Protein Secretion and Inflammasome Activation in Human Macrophages
    Elina Välimäki, Wojciech Cypryk, Juhani Virkanen, Katariina Nurmi, Pauli M. Turunen, Kari K. Eklund, Karl E.O. Åkerman, Tuula A. Nyman, Sampsa Matikainen · 2016 · The Journal of Immunology
  23. Autophagy pathways in autoimmune diseases
    Christian W. Keller, Iannis E. Adamopoulos, Jan D. Lünemann · 2023 · Journal of Autoimmunity
  24. Cathepsin B Contributes to Autophagy-related 7 (Atg7)-induced Nod-like Receptor 3 (NLRP3)-dependent Proinflammatory Response and Aggravates Lipotoxicity in Rat Insulinoma Cell Line
    Shali Li, Leilei Du, Lu Zhang, Yue Hu, Wenchun Xia, Jia Wu, Jing Zhu, Ling‐Ling Chen, Fengqi Zhu, Chunxian Li et al. · 2013 · Journal of Biological Chemistry
  25. Tryptophan Depletion and the Kinase GCN2 Mediate IFN-γ–Induced Autophagy
    Sophie Fougeray, Iadh Mami, Gildas Bertho, Philippe H. Beaune, Éric Thervet, Nicolas Pallet · 2012 · The Journal of Immunology
  26. Modulation of plant autophagy during pathogen attack
    Alexandre Y Leary, Nattapong Sanguankiattichai, Cian Duggan, Yasin Tümtaş, Pooja Pandey, María Eugenia Segretin, Jose Salguero Linares, Zachary Savage, Rui Jin Yow, Tolga O. Bozkurt · 2017 · Journal of Experimental Botany
  27. Autophagy genes function in apoptotic cell corpse clearance duringC. elegansembryonic development
    Shu‐Yi Huang, Kailiang Jia, Ying Wang, Zheng Zhou, Beth Levine · 2012 · Autophagy
  28. The Roles of Autophagy and the Inflammasome during Environmental Stress-Triggered Skin Inflammation
    Rong-Jane Chen, Yu‐Hsuan Lee, Ya-Ling Yeh, Ying‐Jan Wang, Bour-Jr Wang · 2016 · International Journal of Molecular Sciences
  29. CPTP: A sphingolipid transfer protein that regulates autophagy and inflammasome activation
    Shrawan Kumar Mishra, Yong‐Guang Gao, Yibin Deng, Charles Edward Chalfant, Edward H. Hinchcliffe, Rhoderick E. Brown · 2017 · Autophagy
  30. 1-Deoxysphingolipids cause autophagosome and lysosome accumulation and trigger NLRP3 inflammasome activation
    Mario Lauterbach, Víctor Saavedra, Matthew Mangan, Anke Penno, Christoph Thiele, Eicke Latz, Lars Kuerschner · 2020 · Autophagy
  31. The Cell Biology of Tau Secretion
    Maria Merezhko, Riikka‐Liisa Uronen, Henri J. Huttunen · 2020 · Frontiers in Molecular Neuroscience
  32. Myocardial ischemia-reperfusion injury: The balance mechanism between mitophagy and NLRP3 inflammasome
    Li Chen, Linshen Mao, Jin-Yi Xue, Yu-Hong Jian, Zi-Wen Deng, Maryam Mazhar, Yuan Zou, Ping Liu, Mingtai Chen, Gang Luo et al. · 2024 · Life Sciences
  33. Podocyte injury and repair mechanisms
    Francesco Cellesi, Min Li, Maria Pia Rastaldi · 2015 · Current Opinion in Nephrology & Hypertension
  34. Mpl Traffics to the Cell Surface Through Conventional and Unconventional Routes
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  35. The Interplay between NLRs and Autophagy in Immunity and Inflammation
    Letícia A. M. Carneiro, Leonardo Holanda Travassos · 2013 · Frontiers in Immunology
  36. Autophagy and Inflammasome Interplay
    João Demétrio Martins, Joana Manuela Torres Liberal, Ana Beatriz Gonçalves da Silva, Isabel Ferreira, Bruno Miguel Neves, Maria Teresa Cruz · 2015 · DNA and Cell Biology
  37. “Repair Me if You Can”: Membrane Damage, Response, and Control from the Viral Perspective
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  38. Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation
    Allison K. Meyers, Zhan Wang, Wenzheng Han, Qingxia Zhao, Manal Zabalawi, Likun Duan, Juan Liu, Qianyi Zhang, Rajesh Manne, Felipe Lorenzo et al. · 2023 · Cell Reports
  39. Ménage à Trois in stress: DAMPs, redox and autophagy
    Guanqiao Li, Daolin Tang, Michael T. Lotze · 2013 · Seminars in Cancer Biology
  40. The role of autophagy in intracellular pathogen nutrient acquisition
    Shaun P. Steele, Jason Brunton, Thomas H. Kawula · 2015 · Frontiers in Cellular and Infection Microbiology
  41. The specific PKR inhibitor C16 prevents apoptosis and IL-1β production in an acute excitotoxic rat model with a neuroinflammatory component
    Claire Tronel, Guylène Page, Sylvie Bodard, Sylvie Chalon, Daniel Antier · 2013 · Neurochemistry International
  42. Prdx4 limits caspase‐1 activation and restricts inflammasome‐mediated signaling by extracellular vesicles
    Simone Lipinski, Steffen Pfeuffer, Philipp Arnold, Christian Treitz, Konrad Aden, Henriette Ebsen, Maren Falk‐Paulsen, Nicolas Gisch, Antonella Fazio, J. W. Kuiper et al. · 2019 · The EMBO Journal
  43. Extracellular microvesicles promote microglia‐mediated pro‐inflammatory responses to ethanol
    Fulton T. Crews, Jian Zou, Leon G. Coleman · 2021 · Journal of Neuroscience Research
  44. Glia-specific autophagy dysfunction in ALS
    Laura Strohm, Christian Behrends · 2019 · Seminars in Cell and Developmental Biology
  45. The UPR in Neurodegenerative Disease: Not Just an Inside Job
    A. V. van Ziel, W. Scheper · 2020 · Biomolecules
  46. Autophagy and metabolism
    Pei‐Wen Lin, Man‐Ling Chu, Hsiao‐Sheng Liu · 2020 · The Kaohsiung Journal of Medical Sciences
  47. Differential regulation of acid sphingomyelinase in macrophages stimulated with oxidized low‐density lipoprotein (LDL) and oxidized LDL immune complexes: role in phagocytosis and cytokine release
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  48. Structural Insight into Golgi Membrane Stacking by GRASP65 and GRASP55 Proteins
    Yanbin Feng, Wenying Yu, Xinxin Li, Shao‐Yu Lin, Ying Mei Zhou, Junjie Hu, Xinqi Liu · 2013 · Journal of Biological Chemistry
  49. Autophagy Biomarkers Beclin 1 and p62 are Increased in Cerebrospinal Fluid after Traumatic Brain Injury
    Alicia K. Au, Rajesh K. Aneja, Hülya Bayır, Michael J. Bell, Keri L. Janesko‐Feldman, Patrick Michael Kochanek, Robert S. B. Clark · 2016 · Neurocritical Care
  50. Autophagy-Mediated Secretory Pathway is Responsible for Both Normal and Pathological Tau in Neurons
    Seokjo Kang, Sung Min Son, Sung Hoon Baik, Jinhee Yang, Inhee Mook‐Jung · 2019 · Journal of Alzheimer s Disease
  51. The interplay of autophagy and non-apoptotic cell death pathways
    2020 · International Review of Cell and Molecular Biology
  52. GRASP55 regulates the unconventional secretion and aggregation of mutant huntingtin
    Erpan Ahat, Sarah Bui, Jianchao Zhang, Felipe da Veiga Leprevost, Lisa M. Sharkey, Whitney Reid, Alexey I. Nesvizhskii, Henry Lauris Paulson, Yanzhuang Wang · 2022 · Journal of Biological Chemistry
  53. The interplay between autophagy and cGAS-STING signaling and its implications for cancer
    Maximilian Schmid, Patrick Fischer, Magdalena Engl, Joachim Widder, Sylvia Gruber, Dea Slade · 2024 · Frontiers in Immunology
  54. The Microtubule-associated Protein EB1 Links AIM2 Inflammasomes with Autophagy-dependent Secretion
    Lijie Wang, Hsin‐Yi Huang, Meng-Pin Huang, Willisa Liou, Ya‐Ting Chang, Chih‐Ching Wu, David M. Ojcius, Yu‐Sun Chang · 2014 · Journal of Biological Chemistry
  55. Autophagy: a new target or an old strategy for the treatment of Crohn's disease?
    Kris Nys, Patrizia Agostinis, Séverine Vermeire · 2013 · Nature Reviews Gastroenterology & Hepatology
  56. Autophagy in Plasma Cell Ontogeny and Malignancy
    Enrico Milan, Monica Fabbri, Simone Cenci · 2016 · Journal of Clinical Immunology
  57. The Parkinson’s disease-linked protein TMEM230 is required for Rab8a-mediated secretory vesicle trafficking and retromer trafficking
    Myung Jong Kim, Han‐Xiang Deng, Yvette C. Wong, Teepu Siddique, Dimitri Krainc · 2016 · Human Molecular Genetics
  58. FGF2 and IL-1β – explorers of unconventional secretory pathways at a glance
    Maria Teresa Pallotta, Walter Nickel · 2020 · Journal of Cell Science
  59. Fisetin inhibits inflammation and induces autophagy by mediating PI3K/AKT/mTOR signaling in LPS-induced RAW264.7 cells
    Yue Sun, Hong Qin, Huihui Zhang, Xiangling Feng, Lina Yang, De‐Xing Hou, Jihua Chen · 2021 · Food & Nutrition Research
  60. Recent advances in conventional and unconventional vesicular secretion pathways in the tumor microenvironment
    I.-Ying Kuo, Chih‐Hsiung Hsieh, Wan‐Ting Kuo, Chih‐Peng Chang, Yi‐Ching Wang · 2022 · Journal of Biomedical Science
  61. NLRP3 promotes autophagy of urate crystals phagocytized by human osteoblasts
    Isabelle Allaeys, François Marceau, Patrice E. Poubelle · 2013 · Arthritis Research & Therapy
  62. Secretory carrier membrane protein 5 is an autophagy inhibitor that promotes the secretion of α-synuclein via exosome
    Yi An Yang, Meiling Qin, Puhua Bao, Wangchao Xu, Jin Xu · 2017 · PLoS ONE
  63. Sight of Aged Microplastics Adsorbing Heavy Metal Exacerbated Intestinal Injury: A Mechanistic Study of Autophagy-Mediated Toxicity Response
    Weike Shaoyong, Sun Lu, Yujie Gan, Hongli Jin, Wusu Wang, Lin Yin, Yizhen Wang, Mingliang Jin · 2024 · ACS Nano
  64. The Autophagic Machinery in Viral Exocytosis
    Christian Münz · 2017 · Frontiers in Microbiology
  65. A diacidic motif determines unconventional secretion of wild-type and ALS-linked mutant SOD1
    David Cruz-García, Nathalie Brouwers, Juan M. Durán, Gabriel Mora, Amy J. Curwin, Vivek Malhotra · 2017 · The Journal of Cell Biology
  66. Shear stress induces noncanonical autophagy in intestinal epithelial monolayers
    Sun Wook Kim, Jonathan D. Ehrman, Mok‐Ryeon Ahn, Jumpei Kondo, Andrea A. Lopez, Yun Sik Oh, Xander H. Kim, Scott William Crawley, James R. Goldenring, Matthew J. Tyska et al. · 2017 · Molecular Biology of the Cell
  67. HMGB1/IL-1β complexes in plasma microvesicles modulate immune responses to burn injury
    Leon G. Coleman, Robert Maile, Samuel Jones, Bruce A. Cairns, Fulton T. Crews · 2018 · PLoS ONE
  68. Unconventional Pathways of Secretion Contribute to Inflammation
    Michael J. D. Daniels, David Brough · 2017 · International Journal of Molecular Sciences
  69. An emerging case for membrane pore formation as a common mechanism for the unconventional secretion of FGF2 and IL-1β
    David Brough, Pablo Pelegrı́n, Walter Nickel · 2017 · Journal of Cell Science
  70. Autophagy and cancer therapy
    Julio M. Pimentel, Jun Ying Zhou, Gen Sheng Wu · 2024 · Cancer Letters
  71. Checks and Balances between Autophagy and Inflammasomes during Infection
    Stephanie M. Seveau, Joanne Turner, Mikhail A. Gavrilin, Jordi Bertran Torrelles, Luanne Hall‐Stoodley, Jacob S. Yount, Amal O. Amer · 2017 · Journal of Molecular Biology
  72. Unconventional protein secretion triggered by nutrient starvation
    David Cruz-García, Vivek Malhotra, Amy J. Curwin · 2018 · Seminars in Cell and Developmental Biology
  73. Autophagy Enhancing Contributes to the Organ Protective Effect of Alpha-Lipoic Acid in Septic Rats
    Jia Jia, Xiaoying Gong, Yang Zhao, Zhenyu Yang, Kaiqiang Ji, Ting Luan, Bin Zang, Guo‐Fu Li · 2019 · Frontiers in Immunology
  74. Interplay between Cellular and Molecular Mechanisms Underlying Inflammatory Bowel Diseases Development—A Focus on Ulcerative Colitis
    Iuliana Samoilă, Sorina Dinescu, Marieta Costache · 2020 · Cells
  75. LC3B upregulation by NANOG promotes immune resistance and stem-like property through hyperactivation of EGFR signaling in immune-refractory tumor cells
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  76. Patulin induces pyroptosis through the autophagic-inflammasomal pathway in liver
    Qian Chu, Shaopeng Wang, Liping Jiang, Yuhang Jiao, Xiance Sun, Jing Li, Ling Yang, Yunfeng Hou, Ningning Wang, Xiaofeng Yao et al. · 2020 · Food and Chemical Toxicology
  77. Effects of quercetin on diabetic retinopathy and its association with NLRP3 inflammasome and autophagy
    Rong Li, Guomin Yao, Honglin Yan, Li Wang · 2021 · International Journal of Ophthalmology
  78. Podocytes Degrade Endocytosed Albumin Primarily in Lysosomes
    John M. Carson, Kayo Okamura, Hidefumi Wakashin, Kim McFann, Evgenia Dobrinskikh, Jeffrey B. Kopp, Judith Tamara Blaine · 2014 · PLoS ONE
  79. Protein disulfide isomerase externalization in endothelial cells follows classical and unconventional routes
    Thaı́s L. S. Araujo, Julianna D. Zeidler, Percíllia Oliveira, Matheus Henrique Dias, Hugo A. Armelin, Francisco Rafael Martins Laurindo · 2016 · Free Radical Biology and Medicine
  80. Intricate relationships between naked viruses and extracellular vesicles in the crosstalk between pathogen and host
    Susanne G. van der Grein, Kyra A. Y. Defourny, Erik F. J. Slot, Esther N. M. Nolte‐‘t Hoen · 2018 · Seminars in Immunopathology
  81. Autophagy Modulators and Neuroinflammation
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  82. Lysosomal regulation of extracellular vesicle excretion during d-ribose-induced NLRP3 inflammasome activation in podocytes
    Jinni Hong, Owais Mohammad Bhat, Guangbi Li, Sara K. Dempsey, Qinghua Zhang, Joseph K. Ritter, Weiwei Li, Pin‐Lan Li · 2019 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  83. An inverted CAV1 (caveolin 1) topology defines novel autophagy-dependent exosome secretion from prostate cancer cells
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  84. Homing of Antigen-Presenting Cells in Head Kidney and Spleen – Salmon Head Kidney Hosts Diverse APC Types
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  85. Macrophage secretory IL-1β promotes docetaxel resistance in head and neck squamous carcinoma via SOD2/CAT-ICAM1 signaling
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  87. Atg5 but not Atg7 in dendritic cells enhances IL-2 and IFN-γ production by Toxoplasma gondii-reactive CD4+ T cells
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  88. Evolution, role in inflammation, and redox control of leaderless secretory proteins
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  89. Autophagy mediates tumor necrosis factor-α-induced phenotype switching in vascular smooth muscle A7r5 cell line
    Marina García-Miguel, Jaime A. Riquelme, Ignacio Norambuena‐Soto, Pablo Esteban Morales, Fernanda Sanhueza‐Olivares, Constanza Núñez-Soto, David Mondaca‐Ruff, Nicole Cancino-Arenas, Alejandra San Martín, Mario Chiong · 2018 · PLoS ONE
  90. Autophagy and Its Role in Protein Secretion: Implications for Cancer Therapy
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  91. New Insights Into the Golgi Stacking Proteins
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  92. Targeting pyroptosis to regulate ischemic stroke injury: Molecular mechanisms and preclinical evidences
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  93. Comprehensive view of macrophage autophagy and its application in cardiovascular diseases
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  95. The Induction of Endothelial Autophagy and Its Role in the Development of Atherosclerosis
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  96. Autophagy drives plasticity and functional polarization of tumor‐associated macrophages
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  97. Targeting autophagy and neuroinflammation pathways with plant‐derived natural compounds as potential antidepressant agents
    Tahmineh Mokhtari · 2022 · Phytotherapy Research
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  100. Alternaria extract activates autophagy that induces IL-18 release from airway epithelial cells
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