IAPs limit activation of RIP kinases by TNF receptor 1 during development

Cited by (193)

Items 101–193 of 193

1. Death in the fast lane: what's next for necroptosis?
   Andrew Oberst · 2015 · FEBS Journal
2. Inhibitor of Apoptosis Proteins (IAPs) and Their Antagonists Regulate Spontaneous and Tumor Necrosis Factor (TNF)-induced Proinflammatory Cytokine and Chemokine Production
   Conor J. Kearney, Clare Sheridan, Sean P. Cullen, Graham A. Tynan, Susan E. Logue, Inna S. Afonina, Domagoj Vucic, Ed C. Lavelle, Séamus J. Martin · 2012 · Journal of Biological Chemistry
3. Apoptosis in schistosomes: toward novel targets for the treatment of schistosomiasis
   Erinna F. Lee, Neil David Young, Nicholas T. Y. Lim, Robin B. Gasser, Walter Douglas Fairlie · 2014 · Trends in Parasitology
4. 25 years of research put RIPK1 in the clinic
   Lin Liu, Najoua Lalaoui · 2020 · Seminars in Cell and Developmental Biology
5. CNOT3 suppression promotes necroptosis by stabilizing mRNAs for cell death-inducing proteins
   Toru Suzuki, Chisato Kikuguchi, Sahil Sharma, Toshio Sasaki, Miho Tokumasu, Shungo Adachi, Tohru Natsume, Yumi Kanegae, Tadashi S. Yamamoto · 2015 · Scientific Reports
6. IAPs and Cell Death
   John Silke, James Edward Vince · 2016 · Current topics in microbiology and immunology
7. Two Coordinated Mechanisms Underlie Tumor Necrosis Factor Alpha-Induced Immediate and Delayed IκB Kinase Activation
   Ken Blackwell, Laiqun Zhang, Lauren M. Workman, Adrian T. Ting, Kazuhiro Iwaï, Hasem Habelhah · 2013 · Molecular and Cellular Biology
8. Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation
   Holly Anderton, James A. Rickard, George Andrew Varigos, Najoua Lalaoui, John Silke · 2017 · Journal of Investigative Dermatology
9. Formation and removal of poly‐ubiquitin chains in the regulation of tumor necrosis factor‐induced gene activation and cell death
   Sebastian Kupka, Matthias Reichert, Peter Dráber, Henning Walczak · 2016 · FEBS Journal
10. A new perspective of triptolide-associated hepatotoxicity: the relevance of NF- B and NF- B-mediated cellular FLICE-inhibitory protein
    Ziqiao Yuan, Zihang Yuan, Muhammad Hasnat, Haoran Zhang, Peishi Liang, Lixin Sun, Zhenzhou Jiang, Luyong Zhang · 2020 · Acta Pharmaceutica Sinica B
11. The Inhibitor of Apoptosis (IAPs) in Adaptive Response to Cellular Stress
    Arthur Marivin, Jean Berthelet, Stéphanie Plenchette, Laurence Dubrez · 2012 · Cells
12. Characterization of the Ripoptosome and Its Components
    Ramon Schilling, Peter Geserick, Martin Leverkus · 2014 · Methods in enzymology on CD-ROM/Methods in enzymology
13. IAPs Regulate Distinct Innate Immune Pathways to Co-ordinate the Response to Bacterial Peptidoglycans
    Che A. Stafford, Kate E. Lawlor, Valentin J. Heim, Aleksandra Bankovacki, Jonathan P. Bernardini, John Silke, Ueli Nachbur · 2018 · Cell Reports
14. TNFR2 induced priming of the inflammasome leads to a RIPK1-dependent cell death in the absence of XIAP
    Janin Knop, Lisanne M. Spilgies, Stefanie Rufli, Ramona Reinhart, Lazaros Vasilikos, Monica Yabal, Erika Owsley, Philipp Jakob Jost, Rebecca A. Marsh, Harald Wajant et al. · 2019 · Cell Death and Disease
15. Regulatory mechanisms of RIPK1 in cell death and inflammation
    Zhijun Liu, Francis Ka-Ming Chan · 2020 · Seminars in Cell and Developmental Biology
16. The serine threonine kinase RIP3: lost and found
    Michael J. Morgan, You‐Sun Kim · 2015 · BMB Reports
17. Predication of the underlying mechanism of Bushenhuoxue formula acting on knee osteoarthritis via network pharmacology-based analyses combined with experimental validation
    Huihui Xu, Suo-Mi Li, Rui Xu, Liang Fang, Hui Ying Xu, Peijian Tong · 2020 · Journal of Ethnopharmacology
18. The FLIP Side of Life
    John Silke, Andreas Strasser · 2013 · Science Signaling
19. RIP1 post-translational modifications
    Eugene Varfolomeev, Domagoj Vucic · 2022 · Biochemical Journal
20. IAP gene deletion and conditional knockout models
    John Silke, David Lawrence Vaux · 2014 · Seminars in Cell and Developmental Biology
21. The small molecule that packs a punch: ubiquitin-mediated regulation of RIPK1/FADD/caspase-8 complexes
    Rebecca Feltham, John Silke · 2017 · Cell Death and Differentiation
22. Cell death in cancer
    Marcus Conrad, Andreas Strasser, Philipp Jakob Jost, Junying Yuan, Feng Shao, Peter Vandenabeele, Adam Wahida · 2026 · Cell
23. Targeting RIP Kinases in Chronic Inflammatory Disease
    Mary Speir, Tirta Mario Djajawi, Stephanie A. Conos, Hazel Tye, Kate E. Lawlor · 2021 · Biomolecules
24. The flick of a switch: which death program to choose?
    Peter Vandenabeele, Gerry Melino · 2012 · Cell Death and Differentiation
25. RIPK1 ubiquitination: Evidence, correlations and the undefined
    Daniel S. Simpson, Anna Gabrielyan, Rebecca Feltham · 2020 · Seminars in Cell and Developmental Biology
26. Developmental checkpoints guarded by regulated necrosis
    Christopher P. Dillon, Bart Tummers, Katherine Baran, Douglas R. Green · 2016 · Cellular and Molecular Life Sciences
27. A unique death pathway keeps RIPK1 D325A mutant mice in check at embryonic day 10.5
    Yingying Zhang, Kai Huang, Yuxia Zhang, Han Tao, Lang Li, Chenchen Ruan, Ye-hsuan Sun, Wenke Shi, Wei Han, Suqin Wu et al. · 2021 · PLoS Biology
28. A Discrete Ubiquitin-Mediated Network Regulates the Strength of NOD2 Signaling
    Justine T. Tigno-Aranjuez, Xiaodong Bai, Derek W. Abbott · 2012 · Molecular and Cellular Biology
29. Cytoplasmic and Nuclear Functions of cIAP1
    Aymeric Zadoroznyj, Laurence Dubrez · 2022 · Biomolecules
30. cIAPs control RIPK1 kinase activity‐dependent and ‐independent cell death and tissue inflammation
    Fabian Schorn, J Paul Werthenbach, M. Hoffmann, Mila Daoud, Johanna Stachelscheid, Lars Mortimer Schiffmann, Ximena Hildebrandt, Su Ir Lyu, Nieves Peltzer, Alexander Quaas et al. · 2023 · The EMBO Journal
31. Tumor Necrosis Factor Receptor Superfamily in T Cell Priming and Effector Function
    James Muller, Audrey Baeyens, Michael Loran Dustin · 2018 · Advances in immunology
32. cIAP2 supports viability of mice lacking cIAP1 and XIAP
    Kristen N. Heard, Mathieu J.M. Bertrand, Philip A. Barker · 2015 · The EMBO Journal
33. TNF controls a speed-accuracy tradeoff in the cell death decision to restrict viral spread
    Jennifer E. Oyler, Alon Oyler‐Yaniv, Evan Maltz, Roy Wollman · 2021 · Nature Communications
34. Cleavage of cFLIP restrains cell death during viral infection and tissue injury and favors tissue repair
    Kristel Martinez Lagunas, Deniz Pinar Savcigil, Matea Zrilić, Carlos Carvajal Fraile, Andrew Craxton, Emily L. Self, Iratxe Uranga-Murillo, Diego de Miguel, Maykel A. Arias, Sebastian Willenborg et al. · 2023 · Science Advances
35. Applications and considerations for the use of genetically engineered mouse models in drug development
    Joshua D. Webster, Sara Francesca Santagostino, Oded Foreman · 2019 · Cell and Tissue Research
36. A critical role for cellular inhibitor of protein 2 (cIAP2) in colitis-associated colorectal cancer and intestinal homeostasis mediated by the inflammasome and survival pathways
    Maryse Dagenais, Jeremy Dupaul-Chicoine, Claudia Champagne, Alexander M. Skeldon, Alexandre Morizot, Maya Saleh · 2015 · Mucosal Immunology
37. RIPK3 in necroptosis and cancer
    Michael John Morgan, You‐Sun Kim · 2025 · Molecules and Cells
38. The Antigastric Cancer Effect of Triptolide is Associated With H19/NF-κB/FLIP Axis
    Weiwei Yuan, Jinxi Huang, Shanshan Hou, Huahua Li, Liangyu Bie, Beibei Chen, Gaofeng Li, Yang Zhou, Xiaobing Chen · 2022 · Frontiers in Pharmacology
39. Fn14 and TNFR2 as regulators of cytotoxic TNFR1 signaling
    Daniela Siegmund, Olena Zaitseva, Harald Wajant · 2023 · Frontiers in Cell and Developmental Biology
40. Reduced-Intensity/Reduced-Toxicity Conditioning Approaches Are Tolerated in XIAP Deficiency but Patients Fare Poorly with Acute GVHD
    Danielle E. Arnold, Rofida Nofal, Connor Wakefield, Kai Lehmberg, Katharina Wustrau, Michael H. Albert, Emma C. Morris, Jennifer R. Heimall, Nancy Bunin, Ashish R. Kumar et al. · 2021 · Journal of Clinical Immunology
41. Programmed cell death with a necrotic-like phenotype
    Michael J. Morgan, Zheng-gang Liu · 2013 · BioMolecular Concepts
42. Close Relationship between cIAP2 and Human ARDS Induced by Severe H7N9 Infection
    Chu Qin, Xiaoyan Sai, Xiu-fen Qian, Wu Shui Yan, Li-fei Zou, Hongmei Wang, Tao Bian, Zheng Yan · 2019 · BioMed Research International
43. Structural insights of homotypic interaction domains in the ligand-receptor signal transduction of tumor necrosis factor (TNF)
    Young-Hoon Park, Mi Suk Jeong, Se Bok Jang · 2016 · BMB Reports
44. Ubiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of Homeostasis
    Pascal Meier, Otto Morris, Meike Broemer · 2015 · Current topics in developmental biology/Current Topics in Developmental Biology
45. Ethanol induces necroptosis in gastric epithelial cells in vitro
    Jian‐Ning Liu, Meng Guo, Xiaotong Fan · 2021 · Journal of Food Biochemistry
46. Manifold role of ubiquitin in Helicobacter pylori infection and gastric cancer
    Olga V. Sokolova, Michael Naumann · 2021 · Cellular and Molecular Life Sciences
47. IAPs protect host target tissues from graft-versus-host disease in mice
    Tomomi Toubai, Corinne Rossi, Katherine I. Oravecz-Wilson, Chen Liu, Cynthia K. Zajac, Shin-Rong Julia Wu, Yaping Sun, Hideaki Fujiwara, Hiroya Tamaki, Daniel Peltier et al. · 2017 · Blood Advances
48. Immune dysregulation in SHARPIN-deficient mice is dependent on CYLD-mediated cell death
    Rosalind L. Ang, Mark Chan, Diana Legarda, John P. Sundberg, Shao‐Cong Sun, Virginia Gillespie, Nicholas H. Chun, Peter S. Heeger, Huabao Xiong, Sérgio A. Lira et al. · 2021 · Proceedings of the National Academy of Sciences
49. c-IAP1 and c-IAP2 Redundancy Differs between T and B Cells
    Maria Letizia Giardino Torchia, Dietrich B. Conze, Jonathan D. Ashwell · 2013 · PLoS ONE
50. c‐IAP ubiquitin protein ligase activity is required for 4‐1BB signaling and CD8+ memory T‐cell survival
    Maria Letizia Giardino Torchia, Ivana Munitić, Ehydel Castro, Jasmin Herz, Dorian B. McGavern, Jonathan D. Ashwell · 2015 · European Journal of Immunology
51. Cellular inhibitor of apoptosis-2 is a critical regulator of apoptosis in airway epithelial cells treated with asthma-related inflammatory cytokines
    Eugene Roscioli, Rhys Hamon, Richard E. Ruffin, Susan Elizabeth Lester, Peter D. Zalewski · 2013 · Physiological Reports
52. IAP antagonization promotes inflammatory destruction of vascular endothelium
    Axel Witt, Jens Michael Seeger, Oliver Coutelle, Paola Zigrino, Pia Nora Broxtermann, Maria Andree, Kerstin Brinkmann, Christian Jüngst, Astrid C Schauss, Stephan Schüll et al. · 2015 · EMBO Reports
53. New Insights into the Role of Ubiquitin Networks in the Regulation of Antiapoptosis Pathways
    Tomoko Asaoka, Fumiyo Ikeda · 2015 · International review of cytology
54. Ripoptocide – A Spark for Inflammation
    Rosalind L. Ang, Mark Chan, Adrian T. Ting · 2019 · Frontiers in Cell and Developmental Biology
55. Receptor-interacting protein kinase 3-mediated programmed cell necrosis in rats subjected to focal cerebral ischemia-reperfusion injury
    YANRU DONG, CUIFEN BAO, Jingwei Yu, Xia Liu · 2016 · Molecular Medicine Reports
56. IAPs cause resistance to TRAIL-dependent apoptosis in follicular thyroid cancer
    Thomas Artur Werner, Inga Nolten, Levent Dizdar, Jasmin C. Riemer, Sina C. Schütte, Pablo Emilio Verde, Katharina Raba, Matthias Schott, Wolfram Trudo Knoefel, Andreas H. Krieg · 2018 · Endocrine Related Cancer
57. BIRC3 single nucleotide polymorphism associate with asthma susceptibility and the abundance of eosinophils and neutrophils
    Eugene Roscioli, Rhys Hamon, Richard E. Ruffin, Janet F. Grant, Sandra J. Hodge, Peter D. Zalewski, Susan Elizabeth Lester · 2016 · Journal of Asthma
58. BV6 enhances apoptosis in Lung cancer cells by ameliorating caspase expressions through attenuation of XIAP, cIAP-1, and cIAP-2 proteins
    Irfan S. Ahmad, Ayed A. Dera, Safia Irfan, Prasanna Rajagopalan, Mirza Masroor Ali Beg, Mohammad Yahya Alshahrani, Mushtaq Ahmad Mir, Mohammed Abohashrh, Mohammad Mahtab Alam, Shadma Wahab et al. · 2021 · Journal of Cancer Research and Therapeutics
59. XIAP deletion sensitizes mice to TNF-induced and RIP1-mediated death
    Axel Witt, Tatiana Goncharov, Yujung Michelle Lee, Matthias Kist, Monika Dohse, Jeff Eastham, Debra L. Dugger, Kim Newton, Joshua D. Webster, Domagoj Vucic · 2023 · Cell Death and Disease
60. Modulation of apoptotic response by LAR family phosphatases–cIAP1 signaling during urinary tract morphogenesis
    Katherine S. Stewart, You Chi Tang, Maxwell E. R. Shafer, Adda-Lee Graham-Paquin, Maxime Bouchard · 2017 · Proceedings of the National Academy of Sciences
61. Necroptosis in obesity: a complex cell death event
    Zunhai Liu, Simeng Wang, Wentao Wang, Rui Lv, Chao Sun · 2024 · APOPTOSIS
62. Unique BIR domain sets determine inhibitor of apoptosis protein–driven cell death and NOD2 complex signal specificity
    Steven M. Chirieleison, Joseph K. Rathkey, Derek W. Abbott · 2018 · Science Signaling
63. Monogenic disorders of the TNF signalling pathway
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64. Rosiglitazone attenuates hypoxia-induced renal cell apoptosis by inhibiting NF-κB signaling pathway in a PPARγ-dependent manner
    Junyu Wei, Miaoyue Hu, Xiu-Qi Chen, Feng-Ying Lei, Jinshuang Wei, Jie Chen, Xuankai Qin, Yuan‐Han Qin · 2022 · Renal Failure
65. Loss of cIAP1 in Endothelial Cells Limits Metastatic Extravasation through Tumor-Derived Lymphotoxin Alpha
    Lazaros Vasilikos, Kay Hänggi, Lisanne M. Spilgies, Samanta Kisele, Stefanie Rufli, Wendy Wei-Lynn Wong · 2021 · Cancers
66. Cell Death and Cancer
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67. Response to Heard et al
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68. Expanding the toolbox to develop IAP-based degraders of TEAD transcription factors
    Nishma Gupta, Nicole B. Trainor, Mona Radwan, Stephanie Nguyen, Luke J. Duncan, Andrew X. Tang, Julia G. Beveridge, Natasha Silke, Jumana M. Yousef, Ceren Bilgilier et al. · 2026 · Communications Chemistry
69. Endothelial Cell Killing by TAK1 Inhibition: A Novel Anti-angiogenic Strategy in Cancer Therapy
    Nieves Peltzer, Henning Walczak · 2019 · Developmental Cell
70. IAPs and Necroptotic Cell Death
    John Silke, David Lawrence Vaux · 2014 · Springer eBooks
71. Necroptosis
    Ben A. Croker, James A. Rickard, Inbar Shlomovitz, Arshed Al‐Obeidi, Akshay A. D’Cruz, Motti Gerlic · 2018 · Wiley eBooks
72. IAP Proteins and Their Therapeutic Potential
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73. Reconstitution of human pyroptotic cell death in Saccharomyces cerevisiae
    Yanhao Ji, Christine J. Hawkins · 2023 · Scientific Reports
74. cIAPs and XIAP reduce RIPKs to silence
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75. Mechanisms, regulation and clinical relevance of necroptosis
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76. NOX1, Reactive Oxygen Species, JNK, and Necrotic Cell Death
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77. SMAC IAP Addiction in Cancer
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78. InFLUencing Host Survival: cIAP2 Tips the Scales
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79. Dead if You Do, Dead if You Don’t: How Caspase-8 Causes and Prevents Cell Death
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80. Holding RIPK1 on the Ubiquitin Leash in TNFR1
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81. IAPs and Resistance to Death Receptors in Cancer
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82. The cIAP ubiquitin ligases sustain type 3 γδ T and innate lymphoid cells during aging to allow normal cutaneous and mucosal responses
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83. Divergent Effect of Birinapant, BV6 SMAC Mimetic on TNFα induced NF-κB Signaling and Cell Viability in Activated Hepatic Stellate Cell
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84. Apoptosis and inflammasome regulation
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85. Divergent effect of Birinapant, and BV6 SMAC mimetic on TNFα induced NF-κB signaling and cell viability in activated hepatic stellate cells
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86. Influência dos inibidores de apoptose na resposta ao furoato de mometasona em pacientes com rinossinusite crônica com pólipo nasal
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88. Zbtb38 transcriptionally activates XIAP to regulate apoptosis in development and cancer
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89. IAP-based biodegraders can convert necroptosis to apoptosis and eliminate cancer driving protein complexes
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90. Role of RIPK1 in the survival and death of hepatocytes : its involvement in murine hepatitis models
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92. Death domain-mediated higher-order oligomerization of RIPK1 drives TNF-induced signaling
    Ying Chen, Li Jianwei, Yaw Bia Tan, Lihua Lai, Ping Liu, Ita Novita Sari, Anandhkumar Raju, Vinh Thang Huynh, Amhed Missael Vargas Velazquez, Samuel Jianjie Yeo et al. · 2026 · Cell Death and Differentiation
93. Single-gRNA CRISPR/eCas9-mediated simultaneous targeting of cIAP1 and cIAP2 in colorectal cancer cells: RNA-seq reveals distinct transcriptomic and apoptotic responses
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