Integrin–TGF‐β crosstalk in fibrosis, cancer and wound healing

Margadant, Coert, Sonnenberg, Arnoud·2010·The EMBO Reports

DOI 10.1038/embor.2009.276

Cited by (654)

Items 201–300 of 654

Foxf2 is required for secondary palate development and Tgfβ signaling in palatal shelf mesenchyme
Ali Moussavi Nik, Jeanette Astorga Johansson, Mozhgan Ghiami, Azadeh Reyahi, Peter Carlsson · 2016 · Developmental Biology
Molecular Cues Guiding Matrix Stiffness in Liver Fibrosis
Takaoki Saneyasu, Riaz Akhtar, Takao Sakai · 2016 · BioMed Research International
Application of nintedanib and other potential anti-fibrotic agents in fibrotic diseases
Feng Liu, George P Bayliss, Shougang Zhuang · 2019 · Clinical Science
Impaired cornea wound healing in a tenascin C-deficient mouse model
Takayoshi Sumioka, Ai Kitano, Kathleen Corey Flanders, Yuka Okada, Osamu Yamanaka, Norihito Fujita, Hiroki Iwanishi, Winston W.‐Y. Kao, Shizuya Saika · 2012 · Laboratory Investigation
Hitting the Target! Challenges and Opportunities for TGF-β Inhibition for the Treatment of Cardiac fibrosis
Maria Vistnes · 2024 · Pharmaceuticals
The Role of Extracellular Matrix Quality in Pulmonary Fibrosis
Jacob Hull Kristensen, M.A. Karsdal, Federica Genovese, Simon R. Johnson, Birte Svensson, Susanne Jacobsen, Per Hägglund, Diana Julie Leeming · 2014 · Respiration
Epithelial Plasticity in Cancer: Unmasking a MicroRNA Network for TGF-β-, Notch-, and Wnt-Mediated EMT
Eugenio Zoni, Gabri van der Pluijm, Peter Clarke Gray, Marianna Kruithof‐de Julio · 2015 · Journal of Oncology
AGGF1 therapy inhibits thoracic aortic aneurysms by enhancing integrin α7-mediated inhibition of TGF-β1 maturation and ERK1/2 signaling
Xingwen Da, Ziyan Li, Xiaofan Huang, Zuhan He, Yubing Yu, Tongtong Tian, Chengqi Xu, Yufeng Yao, Qing Kenneth Wang · 2023 · Nature Communications
Zinc oxide nanoparticles for skin wound healing: A systematic review from the perspective of disease types
Di Xiao, Yingyi Huang, Zhonghan Fang, Danyang Liu, Qi Wang, Yichen Xu, Ping Li, Jiang Li · 2025 · Materials Today Bio
A novel role of BMP4 in adult hematopoietic stem and progenitor cell homing via Smad independent regulation of integrin-α4 expression
Satish Khurana, Shannon M. Buckley, Sarah Schouteden, Stephen Carl Ekker, Anna Petryk, Michel Delforge, An Zwijsen, Catherine M. Verfaillie · 2012 · Blood
Natural SIRT1 modifiers as promising therapeutic agents for improving diabetic wound healing
Pranav Kumar Prabhakar, Karmveer Singh, Dhiraj G. Kabra, Jeena Gupta · 2020 · Phytomedicine
Runx2 activates hepatic stellate cells to promote liver fibrosis via transcriptionally regulating Itgav expression
Zhong, Li, Zhao, Jinqiu, Huang, Lu, Liu, Yi, Pang, Xiaoxiao, Zhan, Ke, Li, Shan, Xue, Qian, Pan, Xiaoli, Deng, Liang · 2023 · Clinical and Translational Medicine
Exploration of tumor penetrating peptide iRGD as a potential strategy to enhance tumor penetration of cancer nanotherapeutics
Mohd Aslam Saifi, Gauri Sathish, Mohd Rabi Bazaz, Chandraiah Godugu · 2023 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Tissue-enhanced plasma proteomic analysis for disease stratification in amyotrophic lateral sclerosis
Irene Zubiri, Vittoria Lombardi, Michael Bremang, Vikram Mitra, Giovanni Nardo, Rocco Adiutori, Ching‐Hua Lu, Emanuela Leoni, Ping Kei Yip, Özlem Yildiz et al. · 2018 · Molecular Neurodegeneration
Mechanisms Underlying Adenomyosis-Related Fibrogenesis
Hiroshi Kobayashi, Yohei Kishi, Sho Matsubara · 2019 · Gynecologic and Obstetric Investigation
R e‐epithelialization of wounds
Leeni Koivisto, Lari Häkkinen, Hannu Larjava · 2011 · Endodontic Topics
Hyaluronan, Transforming Growth Factor β, and Extra Domain A-Fibronectin: A Fibrotic Triad
Paula J. McKeown‐Longo, Paul J. Higgins · 2020 · Advances in Wound Care
Bone-matrix mineralization dampens integrin-mediated mechanosignalling and metastatic progression in breast cancer
Siyoung Choi, Matthew A. Whitman, Adrian A. Shimpi, Nicole D. Sempertegui, Aaron E. Chiou, Joseph E. Druso, Akanksha Verma, Stephanie C. Lux, Zhu Cheng, Matthew J. Paszek et al. · 2023 · Nature Biomedical Engineering
TGF-β signaling pathway as a pharmacological target in liver diseases
Sen Zhang, Wu‐Yi Sun, Jingjing Wu, Wei Wei · 2014 · Pharmacological Research
Time-resolved dissection of early phosphoproteome and ensuing proteome changes in response to TGF-β
Rochelle C. J. D’Souza, Anna M. Knittle, Nagarjuna Nagaraj, Maarten van Dinther, Chunaram Choudhary, Peter ten Dijke, Matthias Mann, Kirti Sharma · 2014 · Science Signaling
Injectable Double-Network Hydrogel-Based Three-Dimensional Cell Culture Systems for Regenerating Dental Pulp
Bing Han, Chunling Cao, Aijing Wang, Yanran Zhao, Moran Jin, Yuhan Wang, Shuqin Chen, Min Yu, Zhenzhong Yang, Xiaozhong Qu et al. · 2023 · ACS Applied Materials & Interfaces
WNT1‐inducible signaling protein‐1 mediates TGF‐β1‐induced renal fibrosis in tubular epithelial cells and unilateral ureteral obstruction mouse models via autophagy
Yang, Xue, Wang, Huan, Tu, Yueju, Li, Yi, Zou, Yurong, Li, Guisen, Wang, Li, Zhong, Xiang · 2020 · Journal of Cellular Physiology
Transforming growth factor‐β impairs glucocorticoid activity in the A549 lung adenocarcinoma cell line
Saad Salem, T Harris, JSL Mok, Melody Li, Christine R. Keenan, Michael J. Schuliga, Alastair G. Stewart · 2012 · British Journal of Pharmacology
Altered β1,6‐GlcNAc branched N ‐glycans impair TGF‐β‐mediated Epithelial‐to‐Mesenchymal Transition through Smad signalling pathway in human lung cancer
Na Li, Haineng Xu, Kun Fan, Xijun Liu, Jingjing Qi, Chao Zhao, Peng Yin, Liying Wang, Zengxia Li, Xiliang Zha · 2014 · Journal of Cellular and Molecular Medicine
Heightened inflammation in severe malaria is associated with decreased IL-10 expression levels and neutrophils
Anusree Mahanta, Santosh Kumar Kar, Sanjeeb Kakati, Shravani Baruah · 2014 · Innate Immunity
A proteomics view on integrin‐mediated adhesions
Aki Manninen, Markku T Varjosalo · 2016 · PROTEOMICS
Suppression of integrin α3β1 by α9β1 in the epidermis controls the paracrine resolution of wound angiogenesis
Whitney M. Longmate, Scott P. Lyons, Sridar V. Chittur, Kevin M. Pumiglia, Livingston Van De Water, C. Michael DiPersio · 2017 · The Journal of Cell Biology
Decreased Expression of Decorin and p57(KIP2) Correlates with Poor Survival and Lymphatic Metastasis in Lung Cancer Patients
Rong Biaoxue, Cai Xiguang, Liu Hua, Hui Ma, Yang Shuanying, Wei Zhang, Shang Wenli, Jie Du · 2011 · The International Journal of Biological Markers
Molecular mechanisms of the effect of TGF-β1 on U87 human glioblastoma cells
Igor Bryukhovetskiy, В. Е. Шевченко · 2016 · Oncology Letters
Prostate cancer ETS rearrangements switch a cell migration gene expression program from RAS/ERK to PI3K/AKT regulation
Nagarathinam Selvaraj, Justin A. Budka, Mary W. Ferris, Travis J. Jerde, Peter C. Hollenhorst · 2014 · Molecular Cancer
Teaming Up for Trouble: Cancer Cells, Transforming Growth Factor-β1 Signaling and the Epigenetic Corruption of Stromal Naïve Fibroblasts
Sergio A. Lamprecht, Ina Sigal-Batikoff, Shraga Shany, Naim Abu‐Freha, Eduard Ling, George J. Delinasios, Keren Moyal-Atias, John G. Delinassios, Alexander Fich · 2018 · Cancers
Importance of the stem cell microenvironment for ophthalmological cell-based therapy
Pengxia Wan · 2015 · World Journal of Stem Cells
Integrin-Linked Kinase Is Required for TGF-β1 Induction of Dermal Myofibroblast Differentiation
Linda Vi, Cristina de Lasa, Gianni M. Di Guglielmo, Lina Dagnino · 2010 · Journal of Investigative Dermatology
A novel three-dimensional culture system maintaining the physiological extracellular matrix of fibrotic model livers accelerates progression of hepatocellular carcinoma cells
Yuya Miyauchi, Kentaro Yasuchika, Ken Fukumitsu, Takamichi Ishii, Satoshi Ogiso, Takahito Minami, Hidenobu Kojima, Ryoya Yamaoka, Hokahiro Katayama, Takayuki Kawai et al. · 2017 · Scientific Reports
EW‐7197 prevents ulcerative colitis‐associated fibrosis and inflammation
Maryam Moradi Binabaj, Fereshteh Asgharzadeh, Amir Avan, Farzad Rahmani, Atena Soleimani, Mohammad Reza Parizadeh, Gordon A. Ferns, Mikhail Ryzhikov, Majid Khazaei, Seyed Mahdi Hassanian · 2018 · Journal of Cellular Physiology
Induction of mesenchymal stem cell chondrogenesis by polyacrylate substrates
Laurence Glennon-Alty, Rachel Williams, Simon Dixon, Patricia A. Murray · 2012 · Acta Biomaterialia
Role of TGF-β and IL-6 in dendritic cells, Treg and Th17 mediated immune response during experimental cerebral malaria
Tarun Keswani, Samrat Sarkar, Anirban Sengupta, Arindam Bhattacharyya · 2016 · Cytokine
The Role of Focal Adhesion Kinase in Keratinocyte Fibrogenic Gene Expression
Michael Januszyk, Sun Hyung Kwon, VW Wong, Jagannath Padmanabhan, Zeshaan N. Maan, Alexander J. Whittam, Melanie R. Major, Geoffrey C. Gurtner · 2017 · International Journal of Molecular Sciences
Polydopamine-assisted BMP-2 immobilization on titanium surface enhances the osteogenic potential of periodontal ligament stem cells via integrin-mediated cell-matrix adhesion
Jeong Seok Lee, Jeong‐Chae Lee, Jung Sun Heo · 2018 · Journal of Cell Communication and Signaling
Molecular determinants of mesenchymal cell activation in fibroproliferative diseases
Loka Raghu Kumar Penke, Marc L. Peters-Golden · 2019 · Cellular and Molecular Life Sciences
Glycated Collagen Induces α11 Integrin Expression Through TGF‐β2 and Smad3
Ilana Talior‐Volodarsky, Pamma D. Arora, Yongqiang Wang, Cédric Zeltz, Kim Alexander Connelly, Donald Gullberg, Christopher A. McCulloch · 2014 · Journal of Cellular Physiology
Latent transforming growth factor binding protein 4 regulates transforming growth factor beta receptor stability
Su, C.-T., Huang, J.-W., Chiang, C.-K., Lawrence, E. C., Levine, K. L., Dabovic, B., Jung, C., Davis, E. C., Madan-Khetarpal, S., Urban, Z. · 2015 · Human Molecular Genetics
Elastic Fibre Proteins in Elastogenesis and Wound Healing
Xinyang Zhang, Yasmene F. Alanazi, Thomas A. Jowitt, Alan M. Roseman, Clair Baldock · 2022 · International Journal of Molecular Sciences
Material Strategies for Modulating Epithelial to Mesenchymal Transitions
Emily P. Mihalko, Ashley Carson Brown · 2017 · ACS Biomaterials Science & Engineering
Modulation of αVβ6 integrin in osteoarthritis-related synovitis and the interaction with VTN(381–397 a.a.) competing for TGF-β1 activation
Federica Ciregia, Céline Deroyer, Gaël Cobraiville, Zelda Plener, Olivier Malaise, Philippe Gillet, Marianne Fillet, Michel Malaise, Dominique de Seny · 2021 · Experimental & Molecular Medicine
Targeting the TGF-β signaling pathway for fibrosis therapy: a patent review (2015–2020)
Xuanyi Li, Zi’ang Ding, Zixuan Wu, Yinqiu Xu, Hequan Yao, Kejiang Lin · 2021 · Expert Opinion on Therapeutic Patents
Antioxidants Counteract Nicotine and Promote Migration via RacGTP in Oral Fibroblast Cells
Symone M. San Miguel, Lynne A. Opperman, Edward Pat Allen, JAN E. ZIELINSKI, Kathy K.H. Svoboda · 2010 · Journal of Periodontology
Roles of transforming growth factor‐β1 and OB‐cadherin in porcine cardiac valve myofibroblast differentiation
Huan Wang, Leslie Anne Leinwand, Kristi S. Anseth · 2014 · The FASEB Journal
Spontaneous Extracellular Matrix Accumulation in a Human in vitro Model of Renal Fibrosis Is Mediated by αV Integrins
Hélène Bon, Paul Hales, Simon Lumb, Gill Holdsworth, Timothy S. Johnson, Omar S. Qureshi, Breda M. Twomey · 2019 · The Nephron journals/Nephron journals
Cooperative signaling between integrins and growth factor receptors in fibrosis
Horacio Maldonado, James S. Hagood · 2021 · Journal of Molecular Medicine
Premetastatic niche: ready for new therapeutic interventions?
Alice Zoccoli, Michele Iuliani, Francesco Pantano, Marco Imperatori, Salvatore Intagliata, Bruno Vincenzi, Paolo Marchetti, Nicola Papapietro, Vincenzo Denaro, Giuseppe Tonini et al. · 2012 · Expert Opinion on Therapeutic Targets
Epigenetics and systemic sclerosis
Nezam Altorok, Bashar Kahaleh · 2015 · Seminars in Immunopathology
Dynamic cohesin‐mediated chromatin architecture controls epithelial–mesenchymal plasticity in cancer
Jiyeon Yun, Sang‐Hyun Song, Hwang‐Phill Kim, Sae‐Won Han, Eugene C. Yi, Tae‐You Kim · 2016 · EMBO Reports
Proteolytic and Non-proteolytic Activation of Keratinocyte-Derived Latent TGF-β1 Induces Fibroblast Differentiation in a Wound-Healing Model Using Rat Skin
Shozaburo Hata, Kazuhiko Okamura, Mitsutoki Hatta, Hiroyuki Tako Ishikawa, Jun Yamazaki · 2014 · Journal of Pharmacological Sciences
The interaction of Gα 13 with integrin β 1 mediates cell migration by dynamic regulation of RhoA
Bo Shen, Brian Estevez, Zheng Xu, Barry Kreutz, Andrei V. Karginov, Yanyan Bai, Feng Qian, Norifumi Urao, Deane F. Mosher, Xiaoping Du · 2015 · Molecular Biology of the Cell
Effect of Negative Pressure Wound Therapy on Cellular Fibronectin and Transforming Growth Factor-β1 Expression in Diabetic Foot Wounds
Shao Ling Yang, Lv Yun Zhu, Rui Han, Lei Sun, Jing Tao Dou · 2017 · Foot & Ankle International
An Insight into the Anti-Angiogenic and Anti-Metastatic Effects of Oridonin: Current Knowledge and Future Potential
Nurul Akmaryanti Abdullah, Nur Fariesha Md Hashim, Aula Ammar, Noraina Muhamad Zakuan · 2021 · Molecules
Inflammation and Cancer
Suniti Misra, Vincent Hascall, Roger R. Markwald, Paul E. O’Brien, Shibnath Ghatak · 2017 · Wiley eBooks
Deficiency of α7 Nicotinic Acetylcholine Receptor Attenuates Bleomycin-Induced Lung Fibrosis in Mice
Peiyu Sun, Ling Li, Caiqi Zhao, Mengyao Pan, Zhikang Qian, Xiao Su · 2017 · Molecular Medicine
VEGF , FGF ‐2 and TGF β expression in the normal and regenerating epidermis of geckos: implications for epidermal homeostasis and wound healing in reptiles
Noeline Subramaniam, Jim Petrik, Matthew Kenneth Vickaryous · 2018 · Journal of Anatomy
Shedding New Light on The Role of ανβ3 and α5β1 Integrins in Rheumatoid Arthritis
Arwa Morshed, Abdul Baset Abbas, Jialiang Hu, Hanmei Xu · 2019 · Molecules
Role of fibrillin-2 in the control of TGF-β activation in tumor angiogenesis and connective tissue disorders
Karlijn van Loon, Julia Yemelyanenko, Coert Margadant, Arjan W. Griffioen, Elisabeth J. M. Huijbers · 2020 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
IGFBP-5 enhances epithelial cell adhesion and protects epithelial cells from TGFβ1-induced mesenchymal invasion
Aneesh Vijayan, D. Guha, F. Ameer, Ibtisam Kaziri, Collin Mooney, L. Bennett, Angara Sureshbabu, Elizabeth Tonner, James Beattie, G.J. Allan et al. · 2013 · The International Journal of Biochemistry & Cell Biology
A 3D epithelial–mesenchymal co-culture model of human bronchial tissue recapitulates multiple features of airway tissue remodeling by TGF-β1 treatment
Shinkichi Ishikawa, Kanae Ishimori, Shigeaki Ito · 2017 · Respiratory Research
Secretory vimentin is associated with coronary artery disease in patients and induces atherogenesis in ApoE−/− mice
Dong Gong, Yang Dai, Shuai Chen, Xiao Qun Wang, Xiao Xiang Yan, Ying H. Shen, Jing Liu, ZHEN KUN YANG, Jian Hu, Lin Jun Yu et al. · 2019 · International Journal of Cardiology
Transgenic mice overexpressing CD 109 in the epidermis display decreased inflammation and granulation tissue and improved collagen architecture during wound healing
Joshua Vorstenbosch, Corrie L. Gallant‐Behm, Alissa J. Trzeciak, Stéphane Roy, Thomas A. Mustoe, Anie Philip · 2013 · Wound Repair and Regeneration
Vectorial secretion of CTGF as a cell-type specific response to LPA and TGF-β in human tubular epithelial cells
Jonathan Zuehlke, Astrid Ebenau, Bettina Krueger, Margarete Goppelt‐Struebe · 2012 · Cell Communication and Signaling
Targeting TGFβ Signaling to Address Fibrosis Using Antisense Oligonucleotides
James T. March, Golnoush Golshirazi, Viktorija Cernisova, Heidi Carr, Yee Leong, Ngoc Lu‐Nguyen, Linda J. Popplewell · 2018 · Biomedicines
Impaired healing of cornea incision injury in a TRPV1-deficient mouse
Yuka Nidegawa, Takayoshi Sumioka, Yuka Okada, Peter Sol Reinach, Kathleen Corey Flanders, Chia‐Yang Liu, Osamu Yamanaka, Winston W.‐Y. Kao, Shizuya Saika · 2018 · Cell and Tissue Research
Exploring microRNAs in diabetic chronic cutaneous ulcers: Regulatory mechanisms and therapeutic potential
Xuqiang Nie, Jiufeng Zhao, Hua Ling, Youcai Deng, Xiaohui Li, Yuqi He · 2020 · British Journal of Pharmacology
Multifaceted TGF‐β signaling, a master regulator: From bench‐to‐bedside, intricacies, and complexities
Sana Ahuja, Sufian Zaheer · 2023 · Cell Biology International
High-throughput mRNA and miRNA profiling of epithelial-mesenchymal transition in MDCK cells
Priyank Shukla, Claus Vogl, Barbara Wallner, Doris Rigler, Mathias M. Müller, Sabine Macho‐Maschler · 2015 · BMC Genomics
Galectin 3‐binding protein (LGALS3BP) depletion attenuates hepatic fibrosis by reducing transforming growth factor‐β1 (TGF‐β1) availability and inhibits hepatocarcinogenesis
Dae‐Hwan Kim, Minjeong Sung, Myong‐Suk Park, Eun Gene Sun, Sumin Yoon, Kyung Hyun Yoo, Kamalakannan Radhakrishnan, Sung Yun Jung, Woo‐Kyun Bae, Sang‐Hee Cho et al. · 2024 · 癌症：英文版
Activation of transforming growth factor‐β1 by thrombin via integrins αvβ1, αvβ3, and αvβ5 in buccal fibroblasts: Suppression by epigallocatechin‐3‐gallate
Jenny Zwei‐Chieng Chang, Yu‐Ping Hsieh, Wen‐Hsin Lin, Hsin‐Ming Chen, Mark Yen‐Ping Kuo · 2017 · Head & Neck
Del-1, an Endogenous Inhibitor of TGF-β Activation, Attenuates Fibrosis
Dong-Young Kim, Seung Hwan Lee, Yan Fu, Feifeng Jing, Won‐Young Kim, Sang‐Bum Hong, Jung-A Song, Han Choe, Hyun Jin Ryu, Min-Jung Kim et al. · 2020 · Frontiers in Immunology
Activin A and CCR2 regulate macrophage function in testicular fibrosis caused by experimental autoimmune orchitis
Wei Peng, Artem Kepsch, Till O. Kracht, Hiba Hasan, Rukmali Wijayarathna, Eva Wahle, Christiane Pleuger, Sudhanshu Bhushan, Stefan Günther, Anastasia Christine Kauerhof et al. · 2022 · Cellular and Molecular Life Sciences
Single-Cell Profiling Uncovers the Roles of Endometrial Fibrosis and Microenvironmental Changes in Adenomyosis
Weipin Niu, Yinuo Zhang, Hongyun Liu, Na Liang, Xu Li, Yalin Li, Wei Yao, Wei Shi, Zhiyong Liu · 2023 · Journal of Inflammation Research
Modulation of Smad signaling by non-TGFβ components in myofibroblast generation during wound healing in corneal stroma
Shizuya Saika, Osamu Yamanaka, Yuka Okada, Takayoshi Sumioka · 2015 · Experimental Eye Research
68Ga-Trivehexin PET/CT: a promising novel tracer for primary hyperparathyroidism
Serkan Kuyumcu, Dilara Denizmen, Duygu Has Şimşek, Arzu Poyanlı, Ayşe Kubat Üzüm, Fikret Büyükkaya, Emine Göknur Işık, Semen Yeşil Önder, Nihat Aksakal, Zeynep Gözde Özkan et al. · 2024 · European Journal of Nuclear Medicine and Molecular Imaging
Basement Membranes in the Worm
Matthew R. Clay, David R. Sherwood · 2015 · Current topics in membranes
Roles of Integrins in Gastrointestinal Cancer Metastasis
Sicong Hou, Jiaxin Wang, Wenqian Li, Xin Hao, Qinglei Hang · 2021 · Frontiers in Molecular Biosciences
Up-Regulation of Tension-Related Proteins in Keloids
Edna Suárez‐Pozos, Farhatullah Syed, Teresa A Alonso-Rasgado, Parthasarathi Mandal, Ardeshir Bayat · 2013 · Plastic & Reconstructive Surgery
Fibronectin regulates growth factor signaling and cell differentiation in primary lens cells
Judy K. VanSlyke, Bruce A. Boswell, Linda S. Musil · 2018 · Journal of Cell Science
Human Umbilical Cord Mesenchymal Stem Cells Extricate Bupivacaine-Impaired Skeletal Muscle Function via Mitigating Neutrophil-Mediated Acute Inflammation and Protecting against Fibrosis
Wen-Hong Su, Ching‐Jen Wang, Hung‐Chun Fu, Chien-Ming Sheng, Ching-Chin Tsai, Jai‐Hong Cheng, Pei-Chin Chuang · 2019 · International Journal of Molecular Sciences
Targeting integrins in hepatocellular carcinoma
Yanhua Wu, Xiaojing Qiao, Shouyi Qiao, Long Yu · 2011 · Expert Opinion on Therapeutic Targets
Mechanotransduction for therapeutic approaches: Cellular aging and rejuvenation
Hye-Min Han, Su-Yeon Kim, Dong‐Hwee Kim · 2025 · APL Bioengineering
Bulbine Natalensis and Bulbine Frutescens promote cutaneous wound healing
Nalini Pather, Beverley Kramer · 2012 · Journal of Ethnopharmacology
Dependence of fibroblast infiltration in tumor stroma on type IV collagen-initiated integrin signal through induction of platelet-derived growth factor
Sheng-Yi Chen, Jo-Shi Lin, Huan-Ching Lin, Yan‐Shen Shan, Yu-Jung Cheng, Bei-Chang Yang · 2015 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Myofibroblasts: Biochemical and Proteomic Approaches to Fibrosis
Eiko Honda, Ah-Mee Park, Kōji Yoshida, Masaki Tabuchi, Hiroshi Munakata · 2013 · The Tohoku Journal of Experimental Medicine
Sensory neurons shape local macrophage identity via TGF-β signaling
Julia Kolter, Clarissa-Laura Döring, Samah Sarout, Sebastian Baasch, Lloyd Steele, Reem Alsumati, Gabriel Victor Lucena da Silva, Conceição Elidianne Aníbal Silva, Isadora Marques Paiva, Zohreh Mansoori Moghadam et al. · 2025 · Immunity
The Emerging Role of Cell Adhesion Molecules on Benign Prostatic Hyperplasia
Jiang Liu, Junchao Zhang, Xun Fu, Shu Yang, Yan Li, Jianmin Liu, Michael E. DiSanto, Ping Chen, Xinhua Zhang · 2023 · International Journal of Molecular Sciences
The extracellular matrix regulates the effect of decorin and transforming growth factor beta-2 (TGF-β2) on myoblast migration
Kyle Peter Goetsch, Carola Ulrike Niesler · 2016 · Biochemical and Biophysical Research Communications
The mechanotransduction-immune axis in organ fibrosis: dual regulatory mechanisms and translational therapeutic perspectives
2025
An overview of mechanical microenvironment and mechanotransduction in intervertebral disc degeneration
Wencan Ke, Hanpeng Xu, Chengyi Zhang, Zhiwei Liao, Huaizhen Liang, Bide Tong, Feijun Yuan, Kun Wang, Wenbin Hua, Bingjin Wang et al. · 2025 · Experimental & Molecular Medicine
Induction of integrin β3 by sustained ERK activity promotes the invasiveness of TGFβ-induced mesenchymal tumor cells
Soon-Ki Hong, Jeongrak Park, Ok‐Seon Kwon, Keun-Tae Kim, Gab-Yong Bae, Hyuk‐Jin Cha · 2016 · Cancer Letters
Characterisation of a novel, high affinity and selective αvβ6 integrin RGD-mimetic radioligand
Eleanor R. Hall, Lloyd I. Bibby, Robert J. Slack · 2016 · Biochemical Pharmacology
Integrin α3β1 Represses Reelin Expression in Breast Cancer Cells to Promote Invasion
Abibatou Ndoye, Rakshitha Pandulal Miskin, C. Michael DiPersio · 2021 · Cancers
KYP-2047, an Inhibitor of Prolyl-Oligopeptidase, Reduces GlioBlastoma Proliferation through Angiogenesis and Apoptosis Modulation
Sarah Adriana Scuderi, Giovanna Casili, Alessio Ardizzone, Stefano Forte, Lorenzo Colarossi, Serena Sava, Irene Paterniti, Emanuela Esposito, Salvatore Cuzzocrea, Michela Campolo · 2021 · Cancers
Therapeutic potential of P irfenidone for treating equine corneal scarring
Michael K Fink, Elizabeth A. Giuliano, Ashish Tandon, Rajiv R. Mohan · 2014 · Veterinary Ophthalmology
Interstitial lung disease: Physiopathology in the context of lung growth
Nadia Nathan, Guillaume Thouvenin, Brigitte Fauroux, Harriet Corvol, Annick Clément · 2011 · Paediatric Respiratory Reviews