HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications

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Items 201–300 of 477

1. Synthesis and biological evaluation of santacruzamate A analogues for anti-proliferative and immunomodulatory activity
   Samantha M. Gromek, James A. deMayo, Andrew T. Maxwell, Ashley M. West, Christopher M. Pavlik, Ziyan Zhao, Jin Li, Andrew J. Wiemer, Adam Zweifach, Marcy J. Balunas · 2016 · Bioorganic & Medicinal Chemistry
2. Targeting Head and Neck Cancer Stem Cells
   Andrew C. Birkeland, John Henry J. Owen, Mark E. Prince · 2015 · Journal of Dental Research
3. Vascular endothelial growth factor receptor-3 expression in mycosis fungoides
   Ida J. Pedersen, Andreas Willerslev-Olsen, Claudia S. Vetter‐Kauczok, Thorbjørn Krejsgaard, Britt Thyssing Lauenborg, Katharina Kopp, Carsten Geisler, Charlotte Menne Bonefeld, Qian Zhang, Mariusz A. Wasik et al. · 2012 · Leukemia & lymphoma/Leukemia and lymphoma
4. Histone Acetyltransferase p300/CREB-binding Protein-associated Factor (PCAF) Is Required for All-trans-retinoic Acid-induced Granulocytic Differentiation in Leukemia Cells
   Yoshitaka Sunami, Marito Araki, Shin Kan, Akihiro Ito, Yumi Hironaka, Misa Imai, Soji Morishita, Akimichi Ohsaka, Norio Komatsu · 2017 · Journal of Biological Chemistry
5. Total synthesis of bicyclic depsipeptides spiruchostatins C and D and investigation of their histone deacetylase inhibitory and antiproliferative activities
   Kôichi Narita, Yurie Fukui, Yui Sano, Takao Yamori, Akihiro Ito, Minoru Yoshida, Tadashi Katoh · 2012 · European Journal of Medicinal Chemistry
6. The histone deacetylase inhibitor panobinostat is a potent antitumor agent in canine diffuse large B-cell lymphoma
   Joana Dias, Sandra Isabel Aguiar, Diane M. Pereira, A André, Lurdes Gano, João D. G. Correia, Belmira Carrapiço, Barbara C. Rütgen, Rui Malhó, Conceição Peleteiro et al. · 2018 · Oncotarget
7. Targeting host cell proteases as a potential treatment strategy to limit the spread of SARS‐CoV‐2 in the respiratory tract
   Ismail Amr El‐Shimy, Mahmoud M. A. Mohamed, Syed Shahzad Hasan, Muhammad Abdul Hadi · 2020 · Pharmacology Research & Perspectives
8. cAMP signalling inhibits p53 acetylation and apoptosis via HDAC and SIRT deacetylases
   Martine Müller Kloster, Elin Hallan Naderi, Ingvild Haaland, Bjørn Tore Gjertsen, Heidi Kiil Blomhoff, Soheil Naderi · 2013 · International Journal of Oncology
9. Evaluation of Long-term Transgene Expression in piggyBac-Modified Human T Lymphocytes
   Yozo Nakazawa, Sunandan Saha, Daniel L. Galvan, Leslie E. Huye, Lisa A. Rollins, Cliona M. Rooney, Matthew H. Wilson · 2012 · Journal of Immunotherapy
10. Suberoylanilide hydroxamic acid (vorinostat): its role on equine corneal fibrosis and matrix metalloproteinase activity
    Kevin S. Donnelly, Elizabeth A. Giuliano, Ajay Sharma, Rajiv R. Mohan · 2013 · Veterinary Ophthalmology
11. Dual inhibition of PI3K signaling and histone deacetylation halts proliferation and induces lethality in mantle cell lymphoma
    Hui Guo, Dongfeng Zeng, Hui Zhang, Taylor Bell, Jun Yao, Yang Liu, Shengjian Huang, Carrie J. Li, Elizabeth Lorence, Shouhao Zhou et al. · 2018 · Oncogene
12. Quisinostat is a brain-penetrant radiosensitizer in glioblastoma
    Costanza Lo Cascio, Tigran Margaryan, Ernesto Luna Melendez, James McNamara, Connor I. White, William Knight, Saisrinidhi Ganta, Zorana Opachich, Claudia Cantoni, Wonsuk Yoo et al. · 2023 · JCI Insight
13. Regulatory Effects of Histone Deacetylase Inhibitors on Myeloid-Derived Suppressor Cells
    Yudan Cui, Jingshan Cai, Wenxin Wang, Shengjun Wang · 2021 · Frontiers in Immunology
14. ERK inhibition enhances TSA-induced gastric cancer cell apoptosis via NF-κB-dependent and Notch-independent mechanism
    Jun Yao, Cuijuan Qian, Bei Ye, Xin Zhang, Yong Liang · 2012 · Life Sciences
15. Histones: Controlling Tumor Signaling Circuitry
    Manoela D. Martins Rogerio M. Castilho · 2013 · Journal of Carcinogenesis & Mutagenesis
16. Clinically Applicable Inhibitors Impacting Genome Stability
    Anu Prakash, Juan F. García-Moreno, James A. L. Brown, Emer Bourke · 2018 · Molecules
17. Bridged bicyclic peptides: Structure and function
    Varsha Jagannath Thombare, Craig A. Hutton · 2018 · Peptide Science
18. MEF-2 isoforms' (A-D) roles in development and tumorigenesis
    Kiran Madugula, Ria Mulherkar, Zafar K. Khan, DeGaulle I. Chigbu, Dip Patel, Edward William Harhaj, Pooja Jain · 2019 · Oncotarget
19. Epigenetic targeting of cancer stem cells by polyphenols (cancer stem cells targeting)
    Sorayya Ghasemi, Suowen Xu, Seyed Mohammad Nabavi, Mohammad Amir Amirkhani, Antoni Sureda, Silvia Tejada, Zahra Lorigooini · 2021 · Phytotherapy Research
20. Comprehensive gene expression profiles of NK cell neoplasms identify vorinostat as an effective drug candidate
    Kennosuke Karube, Shinobu Tsuzuki, Noriaki Yoshida, Kotaro Arita, Harumi Kato, Miyuki Katayama, Young Hyeh Ko, Koichi Ohshima, Shigeo Nakamura, Tomohiro Kinoshita et al. · 2013 · Cancer Letters
21. Overview of cancer vaccines
    Alex Kudrin · 2012 · Human Vaccines & Immunotherapeutics
22. The HDAC6‐selective inhibitor is effective against non‐Hodgkin lymphoma and synergizes with ibrutinib in follicular lymphoma
    Dong Hoon Lee, Go Woon Kim, So Hee Kwon · 2019 · Molecular Carcinogenesis
23. HDAC inhibitors induce proline dehydrogenase (POX) transcription and anti-apoptotic autophagy in triple negative breast cancer
    Huan Fang, Guangshi Du, Wu Qiuju, Rong Liu, Ceshi Chen, Jing Chun Feng · 2019 · Acta Biochimica et Biophysica Sinica
24. HDAC4 Regulates the Proliferation, Differentiation and Apoptosis of Chicken Skeletal Muscle Satellite Cells
    Jing Zhao, Xiaoxu Shen, Xinao Cao, Haorong He, Shunshun Han, Yuqi Chen, Can Cui, Yuanhang Wei, Yan Wang, Diyan Li et al. · 2020 · Animals
25. Deregulated Chromatin Remodeling in the Pathobiology of Brain Tumors
    Anastasia Spyropoulou, Christina Piperi, Christos Adamopoulos, Athanasios G. Papavassiliou · 2012 · NeuroMolecular Medicine
26. Sodium valproate potentiates staurosporine‐induced apoptosis in neuroblastoma cells via Akt/survivin independently of HDAC inhibition
    Reecha D. Shah, Jayashree C. Jagtap, S. Mruthyunjaya, Ganesh Vilas Shelke, Radha Pujari, Gowry Das, Padma Shastry · 2012 · Journal of Cellular Biochemistry
27. Resistance to Chemotherapy
    Kevin J. Basile, Andrew E. Aplin · 2012 · Advances in pharmacology
28. Role of epigenome in tumorigenesis and drug resistance
    Qidong Hu, Gyeong Hun Baeg · 2017 · Food and Chemical Toxicology
29. The clinical significance of histone deacetylase-8 in human breast cancer
    Golebagh Rahmani, Saba Sameri, Nooshin Abbasi, Mohammad Abdi, Rezvan Najafi · 2021 · Pathology - Research and Practice
30. Novel histone deacetylase 8 ligands without a zinc chelating group: Exploring an ‘upside-down’ binding pose
    Aditya Sudheer Vaidya, Raghupathi Neelarapu, Antonett Madriaga, He Bai, Emma L. Mendonca, Hazem Abdelkarim, Richard Bruce van Breemen, Sylvie Y. Blond, Pavel A. Petukhov · 2012 · Bioorganic & Medicinal Chemistry Letters
31. Paradoxical Regulation of Hypoxia Inducible Factor-1α (HIF-1α) by Histone Deacetylase Inhibitor in Diffuse Large B-Cell Lymphoma
    Savita Bhalla, Andrew M. Evens, Sheila Prachand, Paul T. Schumacker, Leo I. Gordon · 2013 · PLoS ONE
32. Trichostatin A potentiates TRAIL-induced antitumor effects via inhibition of ERK/FOXM1 pathway in gastric cancer
    Lin Li, Biao Fan, Lian-Hai Zhang, Xiaofang Xing, Xiaojing Cheng, Xiaohong Wang, Ting Guo, Hong Du, Xianzi Wen, Jiafu Ji · 2016 · Tumor Biology
33. Design and synthesis of benzodiazepine analogs as isoform-selective human lysine deacetylase inhibitors
    D. Rajasekhar Reddy, Flavio Ballante, Nancy Zhou, Garland R. Marshall · 2016 · European Journal of Medicinal Chemistry
34. Targeting Type 1 Diabetes: Selective Approaches for New Therapies
    Daniel F. Sheehy, Sean P. Quinnell, Arturo J. Vegas · 2019 · Biochemistry
35. Class I/IIb-Selective HDAC Inhibitor Exhibits Oral Bioavailability and Therapeutic Efficacy in Acute Myeloid Leukemia
    Andrew E. Shouksmith, Justyna M. Gawel, Nabanita Nawar, Diana Sina, Yasir S. Raouf, Shazreh Bukhari, Liying He, Alexandra E Johns, Pimyupa Manaswiyoungkul, Olasunkanmi O. Olaoye et al. · 2019 · ACS Medicinal Chemistry Letters
36. HDAC5 promotes osteosarcoma progression by upregulation of Twist 1 expression
    Jie Chen, Jun Xia, Yong-lin Yu, Siqun Wang, Yibing Wei, Fei-yan Chen, Gangyong Huang, Jingsheng Shi · 2013 · Tumor Biology
37. Phase 1 dose-escalation study of oral abexinostat for the treatment of patients with relapsed/refractory higher-risk myelodysplastic syndromes, acute myeloid leukemia, or acute lymphoblastic leukemia
    Norbert Vey, Thomas Prébet, Claire Thalamas, Aude Charbonnier, Jérôme Rey, Ioana Kloos, Emily Liu, Ying Luan, Remus N. Vezan, Thorsten T. Graef et al. · 2016 · Leukemia & lymphoma/Leukemia and lymphoma
38. Discovery of Novel HDAC3 Inhibitors with PD-L1 Downregulating/Degrading and Antitumor Immune Effects
    Zhiqiang Sun, Chenglong Xu, Jinmei Cheng, Zichao Yang, Ting Liu, Bulian Deng, Xuewen Zhang, Xiaopeng Peng, Jianjun Chen · 2024 · Journal of Medicinal Chemistry
39. Discovery of the First-in-Class Dual-Target ROCK/HDAC Inhibitor with Potent Antitumor Efficacy in Vivo That Trigger Antitumor Immunity
    Churu Mao, Jiebin Fang, Shijie Zou, Yun Yan Huang, Xiaoming Chen, Xia Ding, Zhangyun Fang, Ningjing Zhang, Yijie Lou, Zhe Chen et al. · 2024 · Journal of Medicinal Chemistry
40. Fluorescent analogs of the marine natural product psammaplin A: synthesis and biological activity
    Fabia Hentschel, Florenz Sasse, Thomas Lindel · 2012 · Organic & Biomolecular Chemistry
41. Synthesis, structure activity relationship and biological evaluation of a novel series of quinoline–based benzamide derivatives as anticancer agents and histone deacetylase (HDAC) inhibitors
    Negar Omidkhah, Farzin Hadizadeh, Khalil Abnous, Razieh Ghodsi · 2022 · Journal of Molecular Structure
42. Histone Modifications in Acute Kidney Injury
    Jun Wang, Fengchen Shen, Feng Liu, Shougang Zhuang · 2022 · Kidney Diseases
43. Current understanding of structural and molecular changes in diabetic cardiomyopathy
    Md Sayeed Akhtar, Sirajudeen Shaik Alavudeen, Asif Raza, Mohammad Tarique Imam, Ziad Saeed Almalki, Fauzia Tabassum, Mir Javid Iqbal · 2023 · Life Sciences
44. Manipulating the epigenome for the treatment of urological malignancies
    Colm J. O’Rourke, Vinicius Knabben, Eva M. Bolton, Diarmaid C. Moran, Thomas Hugh Lynch, Donal P. Hollywood, Antoinette Sabrina Perry · 2013 · Pharmacology & Therapeutics
45. Discovery of 1,3-Disubstituted 2,5-Diketopiperazine Derivatives as Potent Class I HDACs Inhibitors
    Guoliang Gong, Jianzhao Qi, Ye Lv, Shuai Dong, Chenyu Cao, Ding Li, Ru Song Zhao, Zhen Li, Xin Chen · 2020 · Chemical and Pharmaceutical Bulletin
46. A novel coumarin-TPA based fluorescent probe for turn-on hypochlorite detection and lipid-droplet-polarity bioimaging in cancer cells
    Xuefeng Wang, Zhiming Gou, Jingjing Lv, Yujing Zuo · 2022 · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy
47. Trichostatin A Modulates Thiazolidinedione-Mediated Suppression of Tumor Necrosis Factor α-Induced Lipolysis in 3T3-L1 Adipocytes
    Juu‐Chin Lu, Yu‐Tzu Chang, Chih‐Tien Wang, Yu‐Chun Lin, Chun-Ken Lin, Zhong-Sheng Wu · 2013 · PLoS ONE
48. Epigenetic modifiers synergize with immune-checkpoint blockade to enhance long-lasting antitumor efficacy
    Marina Baretti, Mark M. Yarchoan · 2021 · Journal of Clinical Investigation
49. Evaluation of Anti-Tumor Efficacy of Vorinostat Encapsulated Self-Assembled Polymeric Micelles in Solid Tumors
    Sri Vishnu Kiran Rompicharla, Prakruti Trivedi, Preeti Kumari, Omkara Swami Muddineti, Sowmya Theegalapalli, Balaram Ghosh, Swati Biswas · 2018 · AAPS PharmSciTech
50. New insights on chromatin modifiers and histone post‐translational modifications in renal cell tumours
    Márcia Vieira‐Coimbra, Rui Henrique, Cármen Jerónimo · 2014 · European Journal of Clinical Investigation
51. Zyflamend, a polyherbal mixture, down regulates class I and class II histone deacetylases and increases p21 levels in castrate-resistant prostate cancer cells
    E‐Chu Huang, Yi Zhao, Guoxun Chen, Seung Joon Baek, Michael F. McEntee, Steven C. Minkin, John Biggerstaff, Jay N. Whelan · 2014 · BMC Complementary and Alternative Medicine
52. Incorporation of histone deacetylase inhibitory activity into the core of tamoxifen – A new hybrid design paradigm
    Anthony F. Palermo, Marine Diennet, Mohamed El Ezzy, Benjamin M. Williams, David Cotnoir‐White, Sylvie Mader, James L. Gleason · 2018 · Bioorganic & Medicinal Chemistry
53. Novel epi-virotherapeutic treatment of pancreatic cancer combining the oral histone deacetylase inhibitor resminostat with oncolytic measles vaccine virus
    Tim Patrick Ellerhoff, Susanne Berchtold, Sascha Venturelli, Markus Burkard, Irina Smirnow, Tanja Wulff, Ulrich M. Lauer · 2016 · International Journal of Oncology
54. Inhibition of breast cancer progression by a novel histone deacetylase inhibitor, LW 479, by down‐regulating EGFR expression
    Jingjie Li, Tao Zhang, Feifei Yang, Yuan He, Fujun Dai, Dan Gao, Yihua Chen, Mingyao Liu, Zhengfang Yi · 2015 · British Journal of Pharmacology
55. Single-Cell Atlas Reveals Fatty Acid Metabolites Regulate the Functional Heterogeneity of Mesenchymal Stem Cells
    Jiayi Xie, Qi Lou, Yunxin Zeng, Yingying Liang, Siyu Xie, Quanhui Xu, Lisha Yuan, Jin Wang, Linjia Jiang, Lisha Mou et al. · 2021 · Frontiers in Cell and Developmental Biology
56. Anticancer Study of a Novel Pan-HDAC Inhibitor MPT0G236 in Colorectal Cancer Cells
    Feng-Lung Tsai, Han-Li Huang, Mei-Jung Lai, Jing‐Ping Liou, Shiow‐Lin Pan, Chia‐Ron Yang · 2023 · International Journal of Molecular Sciences
57. HDAC inhibitors, MS-275 and salermide, potentiates the anticancer effect of EF24 in human pancreatic cancer cells
    Atiye Seda Yar Sağlam, Akın Yılmaz, Hacer İlke Önen, Ebru Alp, Handan Kayhan, Abdullah Ekmekçi · 2016 · EXCLI journal
58. Trichostatin A decreases the levels of MeCP2 expression and phosphorylation and increases its chromatin binding affinity
    Katrina Good, Alexia Martínez de Paz, Monica Varun Tyagi, Manjinder S. Cheema, Anita A. Thambirajah, Taylor L. Gretzinger, Gilda Stefanelli, Robert L. Chow, Oliver A. Krupke, Michael J. Hendzel et al. · 2017 · Epigenetics
59. Supramolecularly self-assembled nano-twin drug for reversing multidrug resistance
    Chenwei Wu, Xu Li, Leilei Shi, Xihui Gao, Jing Li, Xinyuan Zhu, Chuan Zhang · 2018 · Biomaterials Science
60. Inhibition of histone deacetylases, topoisomerases and epidermal growth factor receptor by metal-based anticancer agents: Design & synthetic strategies and their medicinal attributes
    Manpreet Kaur, Loveleen, Raj Kumar · 2020 · Bioorganic Chemistry
61. Dietary control of chromatin
    Zhi‐Guang Huang, Ling Cai, Benjamin P. Tu · 2015 · Current Opinion in Cell Biology
62. Loss of Stat6 affects chromatin condensation in intestinal epithelial cells causing diverse outcome in murine models of inflammation-associated and sporadic colon carcinogenesis
    Tiago De Oliveira, Mallika Ramakrishnan, Michaela A. Diamanti, Paul K. Ziegler, Frank Brombacher, Florian R. Greten · 2018 · Oncogene
63. A novel histone deacetylase inhibitor exerts promising anti‐breast cancer activity via triggering AIFM1‐dependent programmed necrosis
    Peipei Shan, Feifei Yang, Jie Yu, Lirong Wang, Yuhua Qu, Huiran Qiu, Hua Zhang, Sujie Zhu · 2022 · 癌症：英文版
64. Total synthesis of burkholdacs A and B and 5,6,20-tri-epi-burkholdac A: HDAC inhibition and antiproliferative activity
    Yurie Fukui, Kôichi Narita, Singo Dan, Takao Yamori, Akihiro Ito, Minoru Yoshida, Tadashi Katoh · 2014 · European Journal of Medicinal Chemistry
65. Design, Synthesis and Biological Evaluation of Novel Benzoylimidazole Derivatives as Raf and Histone Deacetylases Dual Inhibitors
    Xin Chen, Guoliang Gong, Xinyang Chen, Ruihu Song, Mei Duan, Ruizhi Qiao, Yu Jiao, Jianzhao Qi, Yadong Chen, Yong Zhu · 2019 · Chemical and Pharmaceutical Bulletin
66. MHY218-induced apoptotic cell death is enhanced by the inhibition of autophagy in AGS human gastric cancer cells
    Pyoung Rak Choi, Yong Jung Kang, Bokyung Sung, Jae Hyun Kim, Hyung Ryong Moon, Hae Young Chung, Sung Eun Kim, Moo In Park, Seun Ja Park, Nam Deuk Kim · 2015 · International Journal of Oncology
67. Regulation of retinoic acid synthetic enzymes by WT1 and HDAC inhibitors in 293 cells
    Yifan Li, Lei Wang, Weipeng Ai, Nianhui He, Lin Zhang, Jihui Du, Yong Wang, Xingjian Mao, Junqi Ren, Dan Xu et al. · 2017 · International Journal of Molecular Medicine
68. Getting in (and out of) the loop: regulating higher order telomere structures
    Sarah Luke-Glaser, Heiko Poschke, Brian Luke · 2012 · Frontiers in Oncology
69. Synthesis and Cytotoxicity of a Diazirine‐Based Photopsammaplin
    Fabia Hentschel, Björn Raimer, Gerhard Kelter, Heinz‐Herbert Fiebig, Florenz Sasse, Thomas Lindel · 2014 · European Journal of Organic Chemistry
70. Animacroxam, a Novel Dual-Mode Compound Targeting Histone Deacetylases and Cytoskeletal Integrity of Testicular Germ Cell Cancer Cells
    Gustav Steinemann, Alexandra Dittmer, Weronika Kuzyniak, Björn Hoffmann, Mark G. Schrader, Rainer Schobert, Bernhard Biersack, Bianca Nitzsche, Michael Höpfner · 2017 · Molecular Cancer Therapeutics
71. Studies on the antiproliferative effects of tropolone derivatives in Jurkat T-lymphocyte cells
    Sophia N. Ononye, Michael D. VanHeyst, Charles A. Giardina, Dennis L. Wright, Amy C. Anderson · 2014 · Bioorganic & Medicinal Chemistry
72. Clinical and molecular insights into adenoid cystic carcinoma: Neural crest‐like stemness as a target
    Wendell Gray Yarbrough, Alexander Panaccione, Michael T. Chang, Sergey V. Ivanov · 2016 · Laryngoscope Investigative Otolaryngology
73. HDAC Inhibitors
    Heidi Olzscha, Mina Bekheet, Semira Sheikh, Nicholas Barrie La Thangue · 2016 · Methods in molecular biology
74. Design, synthesis, biological evaluation and molecular docking study of novel chalcone-based hydroxamic acids possessing a central 2, 4-dimethy pyrrole linker as potential HDAC (Histone Deacetylase) inhibitors and anticancer agents
    Mozhdeh Yousefian, Maryam Hashemi, Vahid Eskandarpour, Farzin Hadizadeh, Afshin Zarghi, Razieh Ghodsi · 2024 · Journal of Molecular Structure
75. Design and conduct of early-phase radiotherapy trials with targeted therapeutics: Lessons from the PRAVO experience
    Anne Hansen Ree, Donal P. Hollywood · 2013 · Radiotherapy and Oncology
76. The effects of selected inhibitors of histone modifying enzyme on C6 glioma cells
    Marta Maleszewska, Aleksandra Steranka, Bozena Kaminska · 2014 · Pharmacological Reports
77. The effects of a histone deacetylase inhibitor on biological behavior of diffuse large B-cell lymphoma cell lines and insights into the underlying mechanisms
    Ying Cai, Wenli Cui, Weixiang Chen, Ping Wei, Yayun Chi, Ping Zhang, Rui Bi, Xiaoyan Zhou · 2013 · Cancer Cell International
78. Valproic acid (VPA) promotes the epithelial mesenchymal transition of hepatocarcinoma cells via transcriptional and post-transcriptional up regulation of Snail
    Lei Wu, Hua Feng, Jinhua Hu, Xiangguo Tian, Chunqing Zhang · 2016 · Biomedicine & Pharmacotherapy
79. CCR 20th Anniversary Commentary: Vorinostat—Gateway to Epigenetic Therapy
    Wm. Kevin Kelly, Paul A. Marks, Victoria M. Richon · 2015 · Clinical Cancer Research
80. Antineoplastic activity of plant-derived compounds mediated through inhibition of histone deacetylase: a review
    N. Divya Rajaselvi, M. D. Jida, Kizhakkeppurath Kumaran Ajeeshkumar, Suresh Nair, Preethy John, Zarina Aziz, A. R. Nisha · 2023 · Amino Acids
81. Epigenetic regulation of liver fibrosis
    Agata Page, Derek A. Mann · 2015 · Clinics and Research in Hepatology and Gastroenterology
82. Quantitative Profiling of Lysine Acetylation Reveals Dynamic Crosstalk between Receptor Tyrosine Kinases and Lysine Acetylation
    Bryan D. Bryson, Forest M. White · 2015 · PLoS ONE
83. Design, synthesis, modeling, biological evaluation and photoaffinity labeling studies of novel series of photoreactive benzamide probes for histone deacetylase 2
    Aditya Sudheer Vaidya, Bhargava Karumudi, Emma L. Mendonca, Antonett Madriaga, Hazem Abdelkarim, Richard Bruce van Breemen, Pavel A. Petukhov · 2012 · Bioorganic & Medicinal Chemistry Letters
84. Anticancer potential of the histone deacetylase inhibitor-like effects of flavones, a subclass of polyphenolic compounds: a review
    Prabhat Kumar Singh, Raghuvir Singh Tomar, Srikanta Kumar Rath · 2015 · Molecular Biology Reports
85. Valproic acid exhibits different cell growth arrest effect in three HPV-positive/negative cervical cancer cells and possibly via inducing Notch1 cleavage and E6 downregulation
    Shuyu Feng, Yue Yang, Jingyi Lv, Lichun Sun, Mingqiu Liu · 2016 · International Journal of Oncology
86. A phase I study to determine the pharmacokinetics and urinary excretion of belinostat and metabolites in patients with advanced solid tumors
    Hanna Bailey, Jordan P. McPherson, Erin B. Bailey, Theresa Louise Werner, Sumati V. Gupta, Julia Anne Batten, Guru Reddy, Gajanan Bhat, Sunil Sharma, Neeraj Agarwal · 2016 · Cancer Chemotherapy and Pharmacology
87. Hydroxamic acid derivatives as histone deacetylase inhibitors: a DFT study of their tautomerism and metal affinities/selectivities
    Diana Cheshmedzhieva, Nikolay Toshev, Mariana S. Gerova, Ognyan Petrov, Todor Dudev · 2018 · Journal of Molecular Modeling
88. QSAR Classification Models for Prediction of Hydroxamate Histone Deacetylase Inhibitor Activity against Malaria Parasites
    Eva Hesping, Ming Jang Chua, Marc Pflieger, Yunan Qian, Lilong Dong, Prabhakar Bachu, Ligong Liu, Thomas Kurz, Gillian M. Fisher, Tina S. Skinner‐Adams et al. · 2022 · ACS Infectious Diseases
89. RETRACTED: Profiling of Circulating Tumor Cells for Screening of Selective Inhibitors of Tumor‐Initiating Stem‐Like Cells
    Chia‐Lin Chen, Juan Carlos Hernandez, Dinesh Babu Uthaya Kumar, Tatsuya Machida, Stanley M. Tahara, Anthony B. El-Khoueiry, Meng Li, Vasu Punj, Suresh Kumar Swaminathan, Ameya R. Kirtane et al. · 2023 · Advanced Science · Retracted
90. Stat3 Inhibits PTPN13 Expression in Squamous Cell Lung Carcinoma through Recruitment of HDAC5
    Xiujuan Han, Xue Li, Li Gong, Shaojun Zhu, Yao Li, Shumei Wang, Lan Miao, Wei Zhang, Yanhong Li · 2013 · BioMed Research International
91. Histone deacetylase 5 promotes Wilms' tumor cell proliferation through the upregulation of c-Met
    Xu Cao, DE-HONG LIU, Yun Fei Zhou, Xiangming Yan, Liqun Yuan, Jian Gang Pan, Mingcui Fu, Ting Zhang, JIAN WANG · 2016 · Molecular Medicine Reports
92. Minireview: Therapeutic Implications of Epigenetic Signaling in Breast Cancer
    Tae Gyu Oh, Shu-Ching Wang, George E.O. Muscat · 2016 · Endocrinology
93. Immunomodulatory Effects of Histone Deacetylation Inhibitors in Graft-vs.-Host Disease After Allogeneic Stem Cell Transplantation
    Xiaoxiao Xu, Xiaoqin Li, Yanmin Zhao, He Huang · 2021 · Frontiers in Immunology
94. Epigenetic alterations and advancement of lymphoma treatment
    Shuhui Zhuang, Zhaobo Yang, Zhuangzhuang Cui, Yuanyuan Zhang, Fengyuan Che · 2023 · Annals of Hematology
95. First-in-Human Dose-Escalation Study of the Novel Oral Depsipeptide Class I-Targeting HDAC Inhibitor Bocodepsin (OKI-179) in Patients with Advanced Solid Tumors
    Anna Schreiber, Jodi A. Kagihara, Bradley R. Corr, Sarah Lindsey Davis, Christopher Hanyoung Lieu, Sunnie S. Kim, Antonio Jimeno, D. Ross Camidge, Jud Williams, Amy M. Heim et al. · 2023 · Cancers
96. Epigenetic therapies - a new direction in clinical medicine
    Richard Albert Stein · 2014 · International Journal of Clinical Practice
97. Naturally occurring small molecule compounds that target histone deacetylases and their potential applications in cancer therapy
    Yuki Maemoto, Yuki Shimizu, Ryu Katoh, Akihiro Ito · 2021 · The Journal of Antibiotics
98. Antiproliferation and Antiencystation Effect of Class II Histone Deacetylase Inhibitors on Acanthamoeba castellanii
    Ki‐Back Chu, Hae‐Ahm Lee, Marc Pflieger, Fabian Fischer, Yodita Asfaha, Leandro A. Alves Avelar, Alexander Jan Skerhut, Matthias Ulrich Kassack, Finn K. Hansen, Andrea Schöler et al. · 2022 · ACS Infectious Diseases
99. Codelivery of vorinostat and chloroquine by autophagy-inhibitory hollow ZrO2 nanoshells for synergistic combination chemotherapy
    Jianli Chen, Xiao-Hui Jia, Xinyue Xia, Xuan Wu, Yanneng Xu, Gang Yuan, Zeyun Gu, Kathy Qian Luo, Ming‐Heng Yuan, Ruibin Jiang et al. · 2023 · Chemical Engineering Journal
100. Sequence-Dependent Radiosensitization of Histone Deacetylase Inhibitors Trichostatin A and SK-7041
     Jin Ho Kim, Il Han Kim, Jin Hee Shin, Hak Jae Kim, In Ah Kim · 2013 · Cancer Research and Treatment