The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Extracellular matrix structure governs invasion resistance in bacterial biofilms
Open accessAbstract
Many bacteria are highly adapted for life in communities, or biofilms. A defining feature of biofilms is the production of extracellular matrix that binds cells together. The biofilm matrix provides numerous fitness benefits, including protection from environmental stresses and enhanced nutrient availability. Here we investigate defense against biofilm invasion using the model bacterium Vibrio cholerae. We demonstrate that immotile cells, including those identical to the biofilm resident strain, are completely excluded from entry into resident biofilms. Motile cells can colonize and grow on the biofilm exterior, but are readily removed by shear forces. Protection from invasion into the biofilm interior is mediated by the secreted protein RbmA, which binds mother–daughter cell pairs to each other and to polysaccharide components of the matrix. RbmA, and the invasion protection it confers, strongly localize to the cell lineages that produce it.
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Cites
Bacterial Biofilms: A Common Cause of Persistent Infections
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Beachey, E. H. (1981) · Journal of Infectious Diseases · doi:10.1093/infdis/143.3.325 · Cited by 1,411
Oral multispecies biofilm development and the key role of cell–cell distance
Kolenbrander, P. E., Palmer, R. J., Periasamy, S., & Jakubovics, N. S. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2381 · Cited by 1,309
Biofilm Dispersal: Mechanisms, Clinical Implications, and Potential Therapeutic Uses
Kaplan, J. B. (2010) · Journal of Dental Research · doi:10.1177/0022034509359403 · Cited by 949
Should we stay or should we go: mechanisms and ecological consequences for biofilm dispersal
McDougald, D., Rice, S. A., Barraud, N., Steinberg, P. D., & Kjelleberg, S. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2695 · Cited by 881
Rendueles, O., Kaplan, J. B., & Ghigo, J. (2013) · Environmental Microbiology · doi:10.1111/j.1462-2920.2012.02810.x · Cited by 271
Cited by
Bacterial Quorum Sensing and Microbial Community Interactions
Abisado, R. G., Benomar, S., Klaus, J. R., Dandekar, A. A., & Chandler, J. R. (2018) · mBio · doi:10.1128/mbio.02331-17 · Cited by 674
The Mechanical World of Bacteria
Persat, A., Nadell, C. D., Kim, M. K., Ingremeau, F., Siryaporn, A., Drescher, K., Wingreen, N. S., Bassler, B. L., Gitai, Z., & Stone, H. A. (2015) · Cell · doi:10.1016/j.cell.2015.05.005 · Cited by 615
Self-citationEcology and evolution of antimicrobial resistance in bacterial communities
Bottery, M. J., Pitchford, J. W., & Friman, V.-P. (2021) · The ISME Journal · doi:10.1038/s41396-020-00832-7 · Cited by 396
Liu, J., Wu, Y., Wu, C., Muylaert, K., Vyverman, W., Yu, H.-Q., Muñoz, R., & Rittmann, B. (2017) · Bioresource Technology · doi:10.1016/j.biortech.2017.06.054 · Cited by 339
Mechanomicrobiology: how bacteria sense and respond to forces
Dufrêne, Y. F., & Persat, A. (2020) · Nature Reviews Microbiology · doi:10.1038/s41579-019-0314-2 · Cited by 299
Metadata
- Authors
- Nadell, C. D., Drescher, K., Wingreen, N. S., & Bassler, B. L.
- Venue
- The ISME Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2015-01-20
- Volume
- 9
- Issue
- 8
- Pages
- 1700-1709
- ISSN
- 1751-7362 (ISSN-L)
- 1751-7370
- OpenAlex
- W1992699035
- Cited by
- 217
- References
- 6
- FWCI
- 6.82
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Nadell, C. D., Drescher, K., Wingreen, N. S., & Bassler, B. L. (2015). Extracellular matrix structure governs invasion resistance in bacterial biofilms. The ISME Journal. https://doi.org/10.1038/ismej.2014.246
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
