The DOI matches its Crossref record; 59 of the 59 references it cites were found in a registry or an index.
Microbial dark matter ecogenomics reveals complex synergistic networks in a methanogenic bioreactor
Open accessAbstract
Ecogenomic investigation of a methanogenic bioreactor degrading terephthalate (TA) allowed elucidation of complex synergistic networks of uncultivated microorganisms, including those from candidate phyla with no cultivated representatives. Our previous metagenomic investigation proposed that Pelotomaculum and methanogens may interact with uncultivated organisms to degrade TA; however, many members of the community remained unaddressed because of past technological limitations. In further pursuit, this study employed state-of-the-art omics tools to generate draft genomes and transcriptomes for uncultivated organisms spanning 15 phyla and reports the first genomic insight into candidate phyla Atribacteria, Hydrogenedentes and Marinimicrobia in methanogenic environments. Metabolic reconstruction revealed that these organisms perform fermentative, syntrophic and acetogenic catabolism facilitated by energy conservation revolving around H2 metabolism. Several of these organisms could degrade TA catabolism by-products (acetate, butyrate and H2) and syntrophically support Pelotomaculum. Other taxa could scavenge anabolic products (protein and lipids) presumably derived from detrital biomass produced by the TA-degrading community. The protein scavengers expressed complementary metabolic pathways indicating syntrophic and fermentative step-wise protein degradation through amino acids, branched-chain fatty acids and propionate. Thus, the uncultivated organisms may interact to form an intricate syntrophy-supported food web with Pelotomaculum and methanogens to metabolize catabolic by-products and detritus, whereby facilitating holistic TA mineralization to CO2 and CH4.
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Cites
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Insights into the phylogeny and coding potential of microbial dark matter
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Self-citationMethanogenic archaea: ecologically relevant differences in energy conservation
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Cited by
Huws, S. A., Creevey, C. J., Oyama, L. B., Mizrahi, I., Denman, S. E., Popova, M., Muñoz-Tamayo, R., Forano, E., Waters, S. M., Hess, M., et al. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02161 · Cited by 487
Westerholm, M., Moestedt, J., & Schnürer, A. (2016) · Applied Energy · doi:10.1016/j.apenergy.2016.06.061 · Cited by 339
Yan, M., Treu, L., Campanaro, S., Tian, H., Zhu, X., Khoshnevisan, B., Tsapekos, P., Angelidaki, I., & Fotidis, I. A. (2020) · Chemical Engineering Journal · doi:10.1016/j.cej.2020.126159 · Cited by 128
Metabolic strategies shared by basement residents of the lost City hydrothermal field
Brazelton, W. J., McGonigle, J. M., Motamedi, S., Pendleton, H. L., Twing, K. I., Miller, B. C., Lowe, W. J., Hoffman, A. M., Prator, C. A., Chadwick, G. L., et al. (2022) · Applied and Environmental Microbiology · doi:10.1128/aem.00929-22 · Cited by 36
Unique H2-utilizing lithotrophy in serpentinite-hosted systems
Nobu, M. K., Nakai, R., Tamazawa, S., Mori, H., Toyoda, A., Ijiri, A., Suzuki, S., Kurokawa, K., Kamagata, Y., & Tamaki, H. (2023) · The ISME Journal · doi:10.1038/s41396-022-01197-9 · Cited by 32
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Metadata
- Authors
- Nobu, M. K., Narihiro, T., Rinke, C., Kamagata, Y., Tringe, S. G., Woyke, T., & Liu, W.-T.
- Venue
- The ISME Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2015-01-23
- Volume
- 9
- Issue
- 8
- Pages
- 1710-1722
- ISSN
- 1751-7362 (ISSN-L)
- 1751-7370
- OpenAlex
- W2036972714
- Cited by
- 403
- References
- 59
- FWCI
- 50.49
- Type
- journal article
- Language
- en
- Open access
- bronze
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