The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Animal Models of Atopic Dermatitis
Open accessAbstract
Summary Atopic Dermatitis (AD) is characterized by allergic skin inflammation. A hallmark of AD is a dry itchy skin, due at least in part, to defects in skin genes that are important for maintaning skin barrier function. The pathogenesis of AD remains incompletely understood. Since the description of the Nc/Nga mouse as a spontaneously occurring model of AD, a number of mouse models of AD have been developed. They can be categorized into three groups: 1) Models induced by epicutaneous application of sensitizers; 2) Transgenic mice that either over-express or lack selective molecules; 3) Mice that spontaneously develop AD-like skin lesions. These models have resulted in a better understanding of the pathogenesis of AD. This review discusses these models and emphasizes the role of mechanical skin injury and skin barrier dysfunction in eliciting allergic skin inflammation.
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Cites
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
Langrish, C. L., Chen, Y., Blumenschein, W. M., Mattson, J., Basham, B., Sedgwick, J. D., McClanahan, T., Kastelein, R. A., & Cua, D. J. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20041257 · Cited by 4,099
Veldhoen, M., Hocking, R. J., Atkins, C. J., Locksley, R. M., & Stockinger, B. (2006) · Immunity · doi:10.1016/j.immuni.2006.01.001 · Cited by 3,605
Palmer, C. N. A., Irvine, A. D., Terron-Kwiatkowski, A., Zhao, Y., Liao, H., Lee, S. P., Goudie, D. R., Sandilands, A., Campbell, L. E., Smith, F. J. D., et al. (2006) · Nature Genetics · doi:10.1038/ng1767 · Cited by 2,978
New insights into atopic dermatitis
Leung, D. Y. M., Boguniewicz, M., Howell, M. D., Nomura, I., & Hamid, Q. A. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21060 · Cited by 1,435
Atopic dermatitis and the atopic march
Spergel, J. M., & Paller, A. S. (2003) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2003.09.033 · Cited by 1,229
Cited by
Atopic dermatitis: a disease of altered skin barrier and immune dysregulation
Boguniewicz, M., & Leung, D. Y. M. (2011) · Immunological Reviews · doi:10.1111/j.1600-065x.2011.01027.x · Cited by 1,073
Imai, Y., Yasuda, K., Sakaguchi, Y., Haneda, T., Mizutani, H., Yoshimoto, T., Nakanishi, K., & Yamanishi, K. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1307321110 · Cited by 431
Mast cells in atopic dermatitis
Kawakami, T., Ando, T., Kimura, M., Wilson, B. S., & Kawakami, Y. (2009) · Current Opinion in Immunology · doi:10.1016/j.coi.2009.09.006 · Cited by 362
A Review of the Anti-Inflammatory Effects of Rosmarinic Acid on Inflammatory Diseases
Luo, C., Zou, L., Sun, H., Peng, J., Gao, C., Bao, L., Ji, R., Jin, Y., & Sun, S. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00153 · Cited by 336
Skin Barrier Disruption: A Requirement for Allergen Sensitization?
De Benedetto, A., Kubo, A., & Beck, L. A. (2012) · Journal of Investigative Dermatology · doi:10.1038/jid.2011.435 · Cited by 317
Metadata
- Authors
- Jin, H., He, R., Oyoshi, M., & Geha, R. S.
- Venue
- Journal of Investigative Dermatology
- Publisher
- Elsevier BV
- Published
- 2009-01
- Volume
- 129
- Issue
- 1
- Pages
- 31-40
- ISSN
- 0022-202X (ISSN-L)
- OpenAlex
- W2002797131
- Cited by
- 505
- References
- 5
- FWCI
- 15.48
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.