Epigallocatechin-3-Gallate Improves Acne in Humans by Modulating Intracellular Molecular Targets and Inhibiting P. acnes

Yoon, Ji Young, Kwon, Hyuck Hoon, Min, Seong Uk, Thiboutot, Diane M., Suh, Dae Hun·2013·Journal of Investigative Dermatology

Cited by (183)

Items 101–183 of 183

  1. Tea ( Camellia sinensis ) Seed Saponins Act as Sebosuppression Agents via the AMPK / mTOR Pathway
    Jian Li, Yuan‐cheng Huang, Jian‐ming Deng, Min Yu, Christos C. Zouboulis, Guangli Wang, Jing Wang · 2025 · Journal of Cosmetic Dermatology
  2. Phytochemicals as emerging therapeutics for acne vulgaris: a comprehensive review
    Riham A. El‐Shiekh, Rana M. Merghany, Nada Fayez, Mariam Hassan, Alaa F. Bakr, Omneya Eid, Dalia E. Ali, Sherouk Hussein Sweilam · 2025 · Future Journal of Pharmaceutical Sciences
  3. Emerging drugs for the treatment of acne: a review of phase 2 & 3 trials
    Siddharth Bhatt, Rohit Sanjay Kothari, Durga Madhab Tripathy, Sunmeet Sandhu, Mahsa Babaei, Mohamad Goldust · 2022 · Expert Opinion on Emerging Drugs
  4. Plant-Derived Compounds in Cancer Therapy: Traditions of Past and Drugs of Future
    Bee Ling Tan, Mohd Esa Norhaizan · 2018 · Springer eBooks
  5. Addressing the Unmet Need in Acne Management: A Novel Dermocosmetics Guideline Tailored to Asian Patient Subgroups
    Hei Sung Kim, Joo Yeon Ko, Dong Hye Suh, Hwa Jung Ryu, Eunsun Baek, Soyun Cho · 2024 · Cosmetics
  6. Tea and Its Active Ingredients in Preventing and Alleviating Depression: A Comprehensive Review
    Shuangling Xiao, Yi Li, Haiyan Jiang, Sitong Hou, Yaoyao Wang, Di Wang, Jie Teng · 2025 · Foods
  7. Potential of cannabidiol as acne and acne scar treatment: novel insights into molecular pathways of pathophysiological factors
    Jun Hyo Lee, Ji Young Yoon, Dong Hyo Kim, Yoon Gyung Kwon, Geun-Hyeong Kim, Byoung Jun Park, Dae Hun Suh · 2024 · Archives of Dermatological Research
  8. Oral Aqueous Green Tea Extract and Acne Vulgaris: A Placebo-Controlled Study
    Jaclyn M. Forest, Naser Rafikhah · 2014 · Asian Journal of Clinical Nutrition
  9. Effect of afzelin on inflammation and lipogenesis in particulate matter-stimulated C. acnes-treated SZ95 sebocytes
    Ji Yeon Hong, Yong Hee Choi, Yoon Jin Roh, Mi‐Kyung Lee, Christos C. Zouboulis, Kui Young Park · 2025 · Frontiers in Medicine
  10. Herbal bioactive–based cosmetics
    Kenneth Chinedu Ugoeze, Oluwatoyin A. Odeku · 2022 · Elsevier eBooks
  11. The role of mTORC1 in acne pathogenesis and treatment
    Bodo Clemens Melnik · 2013 · Expert Review of Dermatology
  12. An overview of the effect of diet on the allergenicity of cats to susceptible humans
    Charles Gregory Aldrich, Júlia Guazzelli Pezzali, Spencer C Smith · 2018 · SOJ Veterinary Sciences
  13. Alterations in IL-4, IL-10 and IFN-γ levels synergistically decrease lipid content and protein expression of FAS and mature SREBP-1 in human sebocytes
    Jihye Shin, Kun‐Pyo Kim, Hee Yoon Ahn, Bongjoon Kim, Yunhi Cho · 2019 · Archives of Dermatological Research
  14. Efficacy and Safety of Epigallocatechin Gallate in the Treatment and Prevention of Dermatitis: A Systematic Review
    Katarzyna Śladowska, Paweł Moćko, Tomasz Brzostek, Iwona Malinowska‐Lipień, Michał Owca, Paweł Kawalec · 2025 · Biomedicines
  15. Study of EGCG composite hydrogel for the treatment of radiation-induced skin injuries
    Jingying Wang, Lin Gao, Jianbo Song, Sijin Li · 2023 · Journal of Applied Biomaterials & Functional Materials
  16. Plant Extracts in Acne Management: A Narrative Review
    Mathieu Leti, Lucile Garidou, Stéphane V. Cuisiat, Aline Stennevin, Gautier Doat, Céline Mias · 2025 · Dermatology
  17. Complementary and Alternative Methods for Treatment of Acne Vulgaris: a Systematic Review
    Molly R. Marous, Hania K. Flaten, Brigitte Sledge, Hope R Rietcheck, Robert Paul Dellavalle, Tina Suneja, Cory A. Dunnick · 2018 · Current Dermatology Reports
  18. Chlorin e6 and halogen light as a sebostatic photomedicine modulates linoleic acid-induced lipogenesis
    A‐Reum Ryu, Yong‐Wan Kim, Mi-Young Lee · 2018 · Molecular & Cellular Toxicology
  19. Hydroxyproline-Modified Chitosan-Based Hydrogel Dressing Incorporated with Epigallocatechin-3-Gallate Promotes Wound Healing Through Immunomodulation
    Peng Ding, Yanfang Sun, Guohua Jiang, Lei Nie · 2025 · Gels
  20. Rebalancing the Skin: The Microbiome, Acne Pathogenesis, and the Future of Natural and Synthetic Therapies
    M. Beatriz P.P. Oliveira, Ana Colette Maurício, Ana Barros, Cláudia Botelho · 2025 · Molecules
  21. Akne Vulgaris ile Beslenme İlişkisi
    Begümhan Ömeroğlu, Fatma Esra Güneş · 2018 · Hacettepe Üniversitesi Sağlık Bilimleri Fakültesi Dergisi
  22. Efficacy of anti‐sebum moisturizing cream containing 2% l ‐carnitine and 5% epigallocatechin gallate in seborrhea: A randomized clinical trial
    Pipatpong Detudom, Nanticha Kamanamool, Anon Paichitrojjana, Pawat Udompataikul, Montree Udompataikul · 2023 · Journal of Cosmetic Dermatology
  23. Therapeutic potential of r esveratrol: n ovel b iological and p harmacological p erspectives
    Milad Ashrafizadeh · 2025 · Journal of Basic and Clinical Physiology and Pharmacology
  24. Acne and Nutrition
    Gerd Plewig, Bodo Clemens Melnik, WenChieh Chen · 2019 · Springer eBooks
  25. Luteolin ameliorates skin lipid hypersecretion, inflammation and oxidative stress in vivo and in vitro
    Jie Li, Bingyong Mao, Botao Wang, Xin Tang, Qiuxiang Zhang, Tianmeng Zhang, Jianxin Zhao, Hao Zhang, Shumao Cui · 2025 · The Journal of Nutritional Biochemistry
  26. Polyphenol Microneedles for Dermatological Therapy
    Chubao Liu, Jinhui Ran, Zhiping Xie, Xiong Lu, Xiaojing Liu, Chaoming Xie · 2025 · Macromolecular Bioscience
  27. Pleiotropic effects of a Camellia sinensis leaf extract on in vitro and in vivo skin health characteristics
    Daniel D. Shill, Hannah N. Stade, Kayla C. Goodson, Monica A. Beltran, Deana Haller, Meg Benson, Maureen D. Drumwright, Durant Scholz · 2025 · International Journal of Cosmetic Science
  28. Efficacy and Safety of the Traditional Japanese Medicine Keigairengyoto in the Treatment of Acne Vulgaris
    Kotaro Ito, Saori Masaki, Manabu Hamada, Tetsuo Tokunaga, Hisashi Kokuba, Kenji Tashiro, Ichiro Yano, Shinichiro Yasumoto, Shinichi Imafuku · 2018 · Dermatology Research and Practice
  29. Acne Vulgaris and Acne Rosacea
    Hana Grobel, Sarah A. Murphy · 2017 · Elsevier eBooks
  30. Skin-soothing Effects of Oenothera biennis Flower Extract
    Yeji Im, Kyung‐Baeg Roh, Jiyoung You, Suwon Jeon, Eunae Cho, Hong Bae Kim, Deokhoon Park, Eunsun Jung · 2024 · Asian Journal of Beauty and Cosmetology
  31. Medicina alternativa à base de plantas medicinais no tratamento da acne
    Verônica Marin Cubas, João Luiz Coelho Ribas · 2021 · Research Society and Development
  32. Natural products in regeneration
    Rachel B. Wilson, Jason J. Lee, J. Geoffrey Pickering, Nica M. Borradaile · 2021 · Elsevier eBooks
  33. Phytopharmacology of herbal biomolecules
    Rituparna Chaki, Nilanjan Ghosh, Subhash Chandra Mandal · 2021 · Elsevier eBooks
  34. Effect and Tolerability of the Combined Plant Extract (PAC) in Treatment of Acne Vulgaris
    Haesun Park, Sujung Woo, Jinsook Hyun, Hyeonji Kim, Jiyoung You, Hyunju Woo, Eunsun Jung, Kwangseon Jung, Myungok Kim · 2018 · Journal of Cosmetics Dermatological Sciences and Applications
  35. The stimulating effect of extracts of South African plants on melanin production and their antibacterial activity against Cutibacterium acnes
    Namrita Lall, A. G. W. Steyn, Analike Blom van Staden, Thobeka Kentane, Danielle Twilley · 2024 · South African Journal of Botany
  36. Formulation and Physicochemical Characterisation of Niosomes Containing Standardized Hydroalcoholic Extracts of Eucalyptus (Eucalyptus galbie) and Green Tea (Camellia sinensis L.) with Potential Anti-Acne Effect
    Himidreza Bigham, Abbas Pardakhty, Salehe Sabouri, Soodeh Salarpour, Fariba Sharififar · 2025 · Journal of Pharmaceutical Innovation
  37. Comparison of Efficacy of Intradermal Stromal Vascular Fraction Injection Versus Saline Injection in the Treatment of Atrophic Acne Scar: A 10-Week, Prospective, Randomized, Split-Face, Single-Blind Controlled Trial
    Joong Heon Suh, Ji Young Kim, Ji Young Yoon, Jun Hyo Lee, Dong Hyo Kim, Ung Sik Jin, Dae Hun Suh · 2025 · Dermatology and Therapy
  38. Medicinal Plants in the Space Exploration Era: Opportunities and Challenges for Mitigating Spaceflight-Induced Health Hazards
    Francesca Pettinau, Alessandro Orrù · 2026 · Applied Sciences
  39. Adjunctive Antioxidant Benefits in Periodontal Therapy: A Systematic Review and Network Meta‐Analysis
    Jiang Tianle, Haofu Jiang, Wu Jiayu, Yifan Ping, Ma Xinyi, Chen Shuomin, Li Bin, Chen Yang, Mao Yixin, Maria Febbraio et al. · 2026 · Oral Diseases
  40. Polyherbal Antiacne Gel: In Vitro Antibacterial Activity and Efficacy Evaluation Against Cutibacterium acnes
    Praveen Kumar Gaur, Rosaline Mishra, Rahul Kaushik, Krishan Kumar Verma, Nitin Kumar, Kank Lata · 2024 · Assay and Drug Development Technologies
  41. Exploring the potential of herbal bioactives to treat acne: A perspective review
    Pratibha Dhiwar, Trilochan Satapathy, Arun Kumar Sahu, Nikita T. Patel · 2025 · Pharmacological Research - Natural Products
  42. Dietary Inflammatory Index and its relationship with inflammation, metabolic biomarkers and mortality
    Nitin Shivappa · 2014 · Scholar Commons (University of South Carolina)
  43. Protective role of epigallocatechin gallate, a dietary antioxidant against oxidative stress in various diseases
    Punniyakoti Veeraveedu Thanikachalam, S Ramamurthy, Anoop Kumar, Meenakshi Gupta, Garima Bansal · 2020 · Elsevier eBooks
  44. Scientific Connection Between Acne and Diet
    Ji Hoon Yang, Dae Hun Suh · 2021 · Updates in clinical dermatology
  45. Phytotherapy for Acne Vulgaris - a Review
    Adrianna Kruczkowska, Mateusz Pakuła, Wojciech Urbański, Natalia Dolata, Agnieszka Cebula, Emil Bulzacki, Aleksandra Stosiek, Bartosz Balcer, Andrzej Kanturski, Paweł Liszka · 2025 · Journal of Education Health and Sport
  46. Nature’s Remedy: A Comprehensive Review Exploring Herbal Treatments and Natural Approaches for Preventing Acne Vulgaris
    Muskan Shingari, Anjali Sharma, Vishnu Mittal · 2025 · Recent Advances in Anti-Infective Drug Discovery
  47. A Comprehensive Review of Acne Treatments: Unpacking the Chemical Structures and Effective Bioactive Compounds
    Mobina Tajdari, Setare Abolghasemi, Elham Khanniri, Maryam Bayanati, Rahil Hakimimofrad, Mohammad Mahboubi‐Rabbani · 2026 · Health Science Reports
  48. Antimicrobial Blue Light and Acne Vulgaris: Unraveling Therapeutic Insights
    Mara Lúcia Gonçalves Diogo · 2026 · Springer eBooks
  49. Lactobacillus-derived extracellular vesicles provide multi-target acne treatment by enriched proteins and skin microbiota protection
    Liu, Ke, Zhang, Zhiqi, Su, Yuting, Ma, Xinyi, Wang, Jing, Yang, Qianqian, Nie, Qingqing, Mo, Zihao, Zhou, Hong, Zouboulis, Christos C. et al. · 2026 · Journal of Nanobiotechnology
  50. Controlling Staphylococcus aureus skin infections by targeting biofilm and virulence properties using FDA-approved antiseptics and skin care products
    Abirami Karthikeyan, Nazia Tabassum, Aqib Javaid, Taehun Kim, Won-Kyo Jung, Fazlurrahman Khan · 2026 · Folia Microbiologica
  51. Akne Tedavisinde Tamamlayıcı ve Alternatif Tedavi Yöntemleri
    Filiz Topaloğlu Demir · 2020 · TURKDERM
  52. Insulin Resistance Associated Acne
    Raj Kubba · 2021 · Updates in clinical dermatology
  53. Characterisation and Antibacterial Activity of Green Tea Extract-Enriched Solid Goat’s Milk Soap
    Uswatun Chasanah, Dian Eka Ermawati, Utami, Dwi Putri, Hayati, Angela Nora · 2022 · Pharmaceutical Sciences and Research
  54. Epigallocatechin gallate-rich fraction alleviates histamine-induced neurotoxicity in rats via inactivating caspase-3/JNK signaling pathways
    Eman Ibrahim Hassanen, Hayam A. Mansour, Marwa Yousry Issa, Marwa A. Ibrahim, Wafaa A. Mohamed, Mahmoud A. Mahmoud · 2024 · Food and Chemical Toxicology
  55. Targeting the Diet–Gut–Skin Axis for Acne Amelioration: Unveiling Regulatory Mechanisms of Dietary Components and Future Perspectives
    Jie Li, Bingyong Mao, Xin Tang, Qiuxiang Zhang, Jianxin Zhao, Hao Zhang, Shumao Cui · 2025 · Food Reviews International
  56. Does Acute Improvement in Muscle Recovery with Curcumin Supplementation Translate to Long-Term Training?
    Brian Keith McFarlin, E Tanner, Melody A. Gary, Asheal A. Davis, Erin M. Bowman, Richard S. Gary · 2019 · Journal of Science in Sport and Exercise
  57. Green Tea Dregs (Camellia sinensis (L.) Extraction Method Effect on Cutibacterium acnes and Development of Spot Cream
    Maria Odelia Vania Arief, Caroline Lieanto, Jessica Mei Sabani, Purwanto Purwanto · 2023 · JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
  58. Influence du microenvironnement sur la virulence et la formation de biofilm de Cutibacterium acnes.
    Valérie Borrel · 2019
  59. The Effect of Curcumin Supplementation on Physical and Biological Indices of Delayed Onset Muscle Soreness and Inflammation Following Muscle Injury
    Adam S. Venable · 2015
  60. Effects of Green Tea Catechin Polyphenon 60 on the Improvement of Acne Symptoms
    박정혜, Byung-Rae Lee · 2017 · Daehan miyong hakoeji
  61. Complementary Alternative Therapies
    Patrick M. Zito, Robert D. Murgia · 2019 · Journal of the Dermatology Nurses’ Association
  62. Aknede Deri Bakımı
    İlknur Balta, Esra Kıratlı Nalbant · 2020 · TURKDERM
  63. Importance of dermocosmetics in the management of acne
    C. Diehl · 2020 · Ukrainian Journal of Dermatology Venerology Cosmetology
  64. Topical Botanicals in Acne and Rosacea
    Joanna N. Hooten, Lauren Schwartzberg · 2021 · Springer eBooks
  65. Does supplementation with green tea extract improve acne in post-adolescent women? A randomized, double-blind, and placebo-controlled clinical trial
    C.H. Hsua · 2016
  66. Avaliação da pele e cabelos oleosos, desenvolvimento e eficácia clínica de formulações cosméticas contendo extrato de guaraná
    Marcella Gabarra Almeida Leite · 2020
  67. Skin metabolic syndrome and phytonutrients
    Antoni Sureda, Silvia Tejada · 2022 · Elsevier eBooks
  68. Cosmetici per seborrea e acne
    Marie‐Ange Dagnelie, Brigitte Dréno · 2023 · EMC - Cosmetologia Medica e Medicina degli Inestetismi Cutanei
  69. In vitro Anti-acne Properties of Plant Extract Complex Composed of Camellia sinensis L. Leaf and Castanea crenata Bur
    Ji-Young You, Kyung‐Baeg Roh, Song-Ah Choi, Eun-Ae Cho, Se‐Young Oh, Deok-Hoon Park, Eunsun Jung · 2023 · Journal of the Korean Society of Cosmetology
  70. Wybrane zagadnienia z zakresu produkcji surowców, żywności i kosmetyków, t. 3
    2023
  71. Dermatology Life Quality Index (DLQI) Score in Acne Vulgaris after Epigallocatechin-3-Gallate (EGCG) 3% as an Adjuvant of Tretinoin 0,025% Cream
    Farah Meriana Fajrin, Irmadita Citrashanty, M. Yulianto Listiawan, Rahmadewi Rahmadewi, Budi Utomo, Dwi Murtiastutik, Cita Rosita Sigit Prakoeswa · 2023 · Berkala Ilmu Kesehatan Kulit dan Kelamin
  72. Discussion on Targeted Regulation Strategy of Scalp Sub-Health
    嘉莹 梁 · 2024 · Advances in Clinical Medicine
  73. Bioprospecting Nutraceuticals for Human Welfare
    Mangala Hegde, Anamika Mishra, Ajaikumar Bahulayan Kunnumakkara, Bharat Bhushan Aggarwal · 2024 · Springer eBooks
  74. An Extensive Analysis of Acne and Herbal Treatments
    Mapari Akanksha U., F. B., Supekar Rohini K, Bhor Vaishnavi R · 2025 · International Journal of Advanced Research in Science Communication and Technology
  75. International expert consensus recommendations for the use of dermatocosmetics in acne
    Albina N. Khlebnikova · 2025 · Medical alphabet
  76. Nutritional Cosmetology: A Comprehensive Review of Dietary Interventions, supplements, prebiotics, normal flora, and daily habits
    Mohamed Abdelrahman Soliman, Youssef Basem, Hadeel Mohamed, Sara Mansour, Rehab Abdelmonem · 2025 · International Journal of Clinical Medical Research
  77. Truncal Acne: Pathophysiology, Clinical Features, and Management Strategies
    Xiaoyue Feng, Yong Chen, Youting Liu · 2026 · Journal of Cosmetic Dermatology
  78. Valorisation de l'huile de Galba (Calophyllum calaba L.) : isolement, caractérisation et propriétés biologiques de ses actifs
    Leïla Lesaffre · 2016
  79. Effectiveness Test of Epigallocatechin Gallate Cream Formula in Acne Vulgaris Therapy
    Naniek Widyaningrum, Alda Dhea, Alina Rofi, Thendi Abdul Arief, Willi Wahyu Timur · 2026 · Sciences of Pharmacy
  80. Inhibitory Effects of Litchi Extract on Sebum Secretion and Its Mechanism: Evidence From a Mouse Model and Sebaceous Gland Cell Transcriptomics
    Qinqian Tao, Xingmei Chen, Xian Chen, Xiang Yang, Erping Yan · 2026 · Journal of Cosmetic Dermatology
  81. Polyphenol-based nanoparticles enhancing doxycycline efficacy for acne therapy
    Lian Wang, Junmei Song, Hao Wang, Tianyou Wang, Jiaqi Li, Ningrui Cao, Yiwen Li, Zhipeng Gu, Xian Jiang · 2026 · Journal of Materials Chemistry B
  82. Emerging therapies for acne: from metabolic targets to microbiome modulation and precision delivery
    Dongyu Hou, Tengfei Feng, Shuangshuang Wang, Qi Xu, Yuxin Shi, Dexuan Zhuang, Jing Guo, Xunwei Wu · 2026 · Archives of Dermatological Research
  83. Wybrane zagadnienia z zakresu produkcji surowców, żywności i kosmetyków. T. 2
    2022 · Jagiellonian Digital Library (Jagiellonian University)